CLINICAL CHARACTERISTICS AND DIAGNOSIS OF SCHIZOPHRENIA To read up on clinical characteristics and diagnosis of schizophrenia, refer to pages 378–386 of Eysenck’s A2 Level Psychology. Ask yourself What are the difficulties in diagnosing schizophrenia? What are the symptoms of schizophrenia? Can we distinguish the sane from the insane? What you need to know CLINICAL CHARACTERISTICS OF SCHIZOPHRENIA The physical and psychological symptoms of schizophrenia including the positive and negative symptoms and the types of schizophrenia ISSUES SURROUNDING THE CLASSIFICATION AND DIAGNOSIS OF SCHIZOPHRENIA In particular you must consider the issues of reliability and validity Further issues you may consider are: culture bias; social issues, such as public and political attitudes to abnormality; and the economic implications of diagnosis Schizophrenia is a psychotic disorder because it involves a loss of contact with reality (sufferers cannot distinguish between inner experience and external reality) and a lack of self-insight (sufferers do not realise or accept that they are ill). It is based on two Greek words: schizo meaning “split” and phren meaning “mind”, which refers to the splitting of the normal associations between mental processes such as perception, cognition, and emotion. CLINICAL CHARACTERISTICS OF SCHIZOPHRENIA The onset of schizophrenia is typically between the late teens and the mid-30s. About 1% of the population across cultures suffers from schizophrenia during their lives. The symptoms vary somewhat but typically include problems with attention, thinking, social relationships, motivation, and emotion. Physical and Psychological Symptoms of Schizophrenia Physical/behavioural symptoms: Schizophrenics may experience psychomotor poverty (lack of movement) and in extreme cases catatonia, when awkward postures are assumed and the schizophrenic remains motionless in this position for hours at a time. They can exhibit “waxy flexibility” during which their body can be manipulated into different positions. Schizophrenics may fall into a catatonic stupor, during which they lie motionless and appear unaware of their surroundings but are fully conscious throughout. Or increased motor activity can occur, such as stereotypy, purposeless, and repetitive movement. Disorganised, chaotic, and bizarre behaviour can be linked to other symptoms, e.g. covering up all the windows with black paper as a result of cognitive disturbance. Perceptual symptoms: Hallucinations: auditory hallucinations are most common, when the schizophrenic hears voices that are often abusive or offer a critical running commentary on their behaviour. Visual, smell, and taste hallucinations may also be experienced but are less common. Cognitive symptoms: Thought disorders include delusions and thought interference. Delusions of grandeur, persecution, paranoia, and control (sometimes known as alien control symptoms as the schizophrenic believes that their behaviour is under external control) can occur, which can develop during the course of the illness into an increasingly complex web of delusion. Thought insertion (belief that ideas are being planted in their mind), withdrawal (belief that thoughts are being removed from their mind), and broadcasting (belief that others can “tune into” their thoughts) can occur— these are collectively known as thought interference symptoms. Cognitive impairments include intellectual deficits in learning and memory. Most evident are the language impairments such as repeating sounds (echolalia), inventing words (neologisms), jumbled speech (word salad), and nonsensical rhyming (clang associations). The speech is characterised by incoherence and abrupt changes of topic due to cognitive distractibility (inability to maintain a train of thought). Social symptoms: Schizophrenics usually show social withdrawal and may have always lacked social skills. They have little interest in social interactions and do not gain pleasure from them, and so may be aloof, reclusive, and emotionally distant even before the onset of the disorder. Emotional/mood symptoms: Symptoms can include a lack of emotion (emotional blunting) or inappropriate affect (e.g. giggling when told of bereavement). One third of patients suffer depressive symptoms and one in eight patients meet the criteria for a mood disorder as well as schizophrenia and so tend to be diagnosed with schizo-affective disorder. Apathy and a lack of drive, interest, personal care, and hygiene are common and can be linked to the depressed state. Classification of Schizophrenia DSM-IV (Diagnostic and Statistical Manual, 4th edition; see A2 Level Psychology page 378), which is the American classification system, and ICD-10 (International Classification of Diseases), the tenth edition of which was published by the World Health Organization in 1992 (ICD-10; see A2 Level Psychology page 378), are the two most common classification systems. The DSM-IV diagnostic criteria are: 1. Two or more of the symptoms identified above for a period of over 1 month. One symptom only is needed if the delusions are bizarre or if the hallucination is critical and abusive of the individual’s behaviour. 2. The disturbance must be evident over a significant period of time, at least 6 months, including 1 month of pronounced symptoms. 3. The symptoms must have led to a failure to function in social and occupational roles. The ICD-10 criteria are very similar to those used in DSM-IV. The main difference being DSM-IV requires evidence of continuous disturbance for at least 6 months, whereas ICD-10 requires that symptoms must be present for most of the time over a 1-month period. Types of schizophrenia DSM-IV identifies five types of schizophrenia: disorganised, catatonic, paranoid, undifferentiated, and residual. Another common classification is into the positive symptoms (hallucinations, delusions, thought disturbances) of type I schizophrenia or acute disturbance; and the negative symptoms (lack of interest, emotion, motivation, social withdrawal) or type II schizophrenia or chronic disturbance. ISSUES SURROUNDING THE CLASSIFICATION AND DIAGNOSIS OF SCHIZOPHRENIA For any diagnostic system to work effectively, it must possess reliability and validity. Reliability means that there is good consistency over time and between different people’s diagnosis of the same patient; the latter is known as inter-judge (or inter-rater) reliability. If a diagnosis of schizophrenia is valid then patients who are diagnosed as suffering from schizophrenia must have the disorder. If a diagnostic system is to be valid, it must also have high reliability. Clearly if a disorder cannot be agreed upon (so low reliability) then all of the different views cannot be correct (so low validity). Whereas a diagnostic system can be reliable but not valid—it can produce consistently wrong diagnoses. In terms of classification, DSM-IV and ICD-10 take a categorical approach, which assumes that all mental disorders are distinct from each other, and that patients can be categorised with a disorder based on their having particular symptoms. However, diagnosing abnormality is not as straightforward as this approach suggests. Issues in the classification and diagnosis of schizophrenia: Comorbidity This refers to a patient who suffers from two or more mental disorders at the same time. Patients with schizophrenia often have other disorders such as major depressive disorder or bipolar disorder or an anxiety disorder. Comorbidity happens because some symptoms are the same across disorders. This creates problems of reliability as there can be inconsistency in which disorder is diagnosed. RESEARCH EVIDENCE Sim et al.’s (2006) study of 142 hospitalised schizophrenic patients, 32% of whom had an additional mental disorder. Issues in the classification and diagnosis of schizophrenia: The continuity approach This suggests that there is a continuum between schizophrenia and normality. RESEARCH EVIDENCE Chapman et al. (1994, see A2 Level Psychology page 381) have found evidence for schizotypy, which is a proneness to developing psychosis (especially schizophrenia). This supports the continuity hypothesis and reduces the reliability with which schizophrenia is diagnosed. The five types of schizophrenia The five types raise issues of reliability and validity: Some of the types of schizophrenia have no symptoms in common, which questions if they can be the same disorder. The undifferentiated schizophrenia type raises issues of reliability and validity because it is basically a “rag bag” category for all those patients with schizophrenia who are hard to classify. There is such diversity of symptoms that two patients with undifferentiated schizophrenia might have no common symptoms. Another issue is residual schizophrenia. There can be inconsistency in judgements as to whether schizophrenia cases have reduced sufficiently to be categorised as residual. It can also be difficult to decide if the patient has recovered or still has residual schizophrenia. Rosenhan’s (1973) research on “being sane in insane places” RESEARCH EVIDENCE Rosenhan (1973, see A2 Level Psychology pages 382–383) found hospital staff could not distinguish between the sane and the insane. This was because they failed to detect pseudo-patients who had faked symptoms (reported hearing indistinct voices saying “empty”, “hollow”, and “thud”) to gain admittance to 12 different psychiatric hospitals and once admitted behaved in a normal manner and said they had no further symptoms to the hospital staff. Seven out of eight participants were diagnosed with schizophrenia. This clearly questions the reliability and validity of diagnosis. EVALUATION Errors made in diagnosis may not be representative of diagnosis under more typical circumstances as psychiatrists do not expect people to fake mental illness. Kety (1974, see A2 Level Psychology pages 382–383) has countered this by pointing out that if a patient faked physical symptoms, then they may similarly be mistakenly diagnosed with a physical illness. The psychiatrists may not have been completely convinced. The pseudopatients were given a very rare diagnosis of “schizophrenia in remission” and most were released in a few days, which suggests the psychiatrists were unconvinced that the patients had really suffered from schizophrenia. Content validity This refers to the extent to which an assessment measure covers the range of symptoms of schizophrenia. Thus, the diagnostic manuals have content validity if they provide detailed information regarding all of the symptoms of schizophrenia. RESEARCH EVIDENCE Jakobsen et al. (2005, see A2 Level Psychology pages 383–384) used the Operational Criteria Checklist (OPCRIT), a symptom checklist with a glossary providing clear and explicit descriptions of the symptoms, to study patients with a history of psychosis. There was good agreement on the diagnosis of schizophrenia when the diagnoses of OPCRIT were compared against those of ICD-10, indicating a high level of reliability. EVALUATION There was also good agreement (and thus high reliability) when ICD-10 and DSM-IV diagnoses were compared. Both of these findings support content validity as the findings suggest they have sufficient detail of symptoms for accurate diagnosis. Measures such as standard semi-structured interviews or the Operational Criteria Checklist possess good content validity. This is because they involve working through all of the symptoms associated with schizophrenia and with other related mental disorders. Criterion validity Any form of assessment for schizophrenia possesses good criterion validity if those diagnosed as having schizophrenia differ in predictable ways from those not diagnosed as schizophrenic. RESEARCH EVIDENCE Comer (2001, see A2 Level Psychology page 384) found that people with schizophrenia are much less likely than non-schizophrenics to be in full-time employment and to have a strong social network. EVALUATION This provides some support for criterion validity but it is not especially convincing. This is because individuals suffering from almost any mental disorder are more likely than healthy individuals to experience social, relationship, and job problems, and so this doesn’t distinguish schizophrenics from patients with other mental disorders. Construct validity This type of validity involves testing hypotheses based on the diagnosis of schizophrenia. RESEARCH EVIDENCE The dopamine hypothesis suggests that schizophrenia is linked to high levels of dopamine and so if individuals with schizophrenia have high levels of dopamine then this would provide some evidence for construct validity. EVALUTION This type of validity raises issues when it is not supported. This is because it is not clear if this is because the diagnosis is wrong or the hypothesis is wrong. The genetic hypothesis offers support. The genetic hypothesis (that schizophrenia has a genetic basis) has reasonable construct validity because it is supported by numerous twin and family studies and genetic factors are probably more important in the development of schizophrenia than almost any other mental disorder. Predictive validity This refers to our ability to predict the eventual outcome for patients who receive a diagnosis of schizophrenia. RESEARCH EVIDENCE The predictive validity of a diagnosis of schizophrenia is reasonable, but not good because there is too much variety in the outcomes of schizophrenia. For example, 20% recover and never have another episode whereas 10% of schizophrenics commit suicide (Birchwood & Jackson, 2001, see A2 Level Psychology page 384). EVALUATION Predictive validity is lowered by the fact there are so many diverse symptoms of schizophrenia that patients’ experiences of the disorder are very different. Mason et al. (1997, see A2 Level Psychology page 385) found predictive validity was higher when a 6-month period of symptoms was used as the basis for diagnosis because this cuts out individuals who have a brief, neverto-be-repeated psychotic disturbance. Social class bias and culture bias Two possible biases, social class bias and culture bias, could reduce reliability and validity. RESEARCH EVIDENCE FOR SOCIAL CLASS BIAS Keith et al. (1991, see A2 Level Psychology page 385) reported that 1.9% of lower-class people, 0.9% of middle-class people, and only 0.4% of upperclass people were diagnosed with schizophrenia. Some experts argue that these differences reflect social class bias. This suggests that lower-class individuals are more likely to be diagnosed with schizophrenia than are middle-class and upper-class individuals who present with the same symptoms. EVALUATION However, we cannot be absolutely certain that this is class bias because there may be differences in incidence of schizophrenia across the classes. RESEARCH EVIDENCE FOR CULTURE BIAS Keith et al. (1991, see A2 Level Psychology page 385) found that 2.1% of African–Americans are diagnosed with schizophrenia, compared with 1.4% of white Americans. McGovern and Cope (1987, see A2 Level Psychology page 385) found twothirds of psychotic patients held in hospitals in Birmingham were African– Caribbean, compared with only one-third who were white and Asian. EVALUATION These findings suggest culture bias, however when adverse life circumstances such as poverty and marital separation were controlled for there was no difference in the incidence of schizophrenia in the two groups. So What Does This Mean? The various symptoms and types of schizophrenia can make this a difficult disorder to diagnose. The Schizophrenia Association of Great Britain (SAGB) uses an umbrella as a symbol to represent schizophrenia in the sense that it is an umbrella term that covers so many forms of mental illness. The many forms of schizophrenia inevitably raise issues of reliability and validity in diagnosis. Yet the two main systems of diagnosis, DSM-IV and ICD-10, have reasonably good content validity as the research findings suggest they have sufficient detail of symptoms for accurate diagnosis. However, there are many issues that question the reliability and validity of diagnosis such as: comorbidity; the continuity between psychosis and normality; criterion, construct, and predictive validity; social class and culture bias; and of course Rosenhan’s (1974) research, which questions whether we can distinguish the sane from the insane. Remember that the issues can be questioned so don’t just focus on the negatives in terms of diagnosis as it is not completely without reliability and validity. Over to you 1. Outline the clinical characteristics of schizophrenia. (5 marks) 2. Discuss the issues associated with classification and diagnosis of schizophrenia. (20 marks)