Clinical Expert Series Identification of Candidates for Progesterone: Why, Who, How, and When? Jay D. Iams, MD Obstet Gynecol 2014;123:1317–26 Continuing Medical Education credit is provided through joint sponsorship with The American College of Obstetricians and Gynecologists. ACCME Accreditation The American College of Obstetricians and Gynecologists (the College) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. AMA PRA Category 1 Credit(s)™ The American College of Obstetricians and Gynecologists designates this enduring material for a maximum of 2 AMA PRA Category 1 Credits.™ Physicians should claim only the credit commensurate with the extent of their participation in the activity. College Cognate Credit(s) The American College of Obstetricians and Gynecologists designates this enduring material for a maximum of 2 Category 1 College Cognate Credits. The College has a reciprocity agreement with the AMA that allows AMA PRA Category 1 Credits™ to be equivalent to College Cognate Credits. Disclosure Statement Current guidelines state that continuing medical education (CME) providers must ensure that CME activities are free from the control of any commercial interest. All authors, reviewers, and contributors have disclosed to the College all relevant financial relationships with any commercial interests. The authors, reviewers, and contributors declare that neither they nor any business associate nor any member of their immediate families has financial interest or other relationships with any manufacturer of products or any providers of services discussed in this program. Any conflicts have been resolved through group and outside review of all content. Submission Before submitting this form, please print a completed copy as confirmation of your program participation. College Fellows: To obtain credits, complete and return this form by e-mail (obgyn@greenjournal.org) or fax (202-479-0830). Your score, and a copy of the answer key, will be e-mailed to you after receipt of a completed quiz. Credit will be recorded for those participants answering 80–100% of questions correctly. College Fellows may check their transcripts online at http://www.acog.org, and any questions related to transcripts may be directed to educationcme@acog.org. For other queries, please contact the Obstetrics & Gynecology Editorial Office, 202-314-2317 (phone) or obgyn@greenjournal.org (e-mail). Non–College Fellows: To obtain credits, submit the printout of the completed quiz to your accrediting institution. The printout of the completed quiz is documentation for your continuing medical education credits. Continuing medical education credit for “Identification of Candidates for Progesterone: Why, Who, How, and When?” will be available through June 2017. 1. The author asserts that responsibility for the prevention of death from preterm birth is now in the hands of: State health departments The federal government Obstetrician–gynecologists Perinatologists Pediatricians CME Quiz for the Clinical Expert Series Obstet Gynecol 2014;123(6) Credit available through June 2017 Page 1 of 3 2. The greatest contributor to overall infant mortality is: Septicemia Maternal drug addiction Prematurity Parental abuse Sudden infant death syndrome (SIDS) 3. The greatest impediment to implementing the results of research regarding the use of progesterone to delay delivery is: Lack of insurance funding Conflicting guidelines for different sources Uncertainty about how to implement guidelines Patient resistance to treatment Cost of treatment 4. Which of the following patients would be a candidate for vaginal progesterone therapy? A patient with a history of a stillbirth at 37 weeks of gestation considering pregnancy A patient currently at 12 weeks of gestation with a history of two prior deliveries at 32 weeks and 28 weeks A patient with a cervical length of 18 mm at 20 weeks of gestation A patient with a cervical length of 26 mm at 22 weeks of gestation A patient with a cervical length of 12 mm at 30 weeks of gestation 5. The author asserts that the optimal gestational age for the initiation of indicated 17αhydroxyprogesterone caproate prophylaxis is: 8–10 weeks 12–15 weeks 16–20 weeks 21–25 weeks 26–30 weeks 6. Women with a prior preterm birth receiving 17α-hydroxyprogesterone caproate whose cervical length falls below 25 mm before 23 weeks are candidates for: Dose escalation Conversion to vaginal progestin therapy Cervical cerclage Continued monitoring Immediate delivery CME Quiz for the Clinical Expert Series Obstet Gynecol 2014;123(6) Credit available through June 2017 Page 2 of 3 7. The first step in the author’s proposed algorithm for identifying patients who might benefit from progestin therapy is: Past obstetric history Family history Transabdominal ultrasonographic measurement of cervical length Transvaginal ultrasonographic measurement of cervical length Review of current symptoms 8. The highest rate of preterm birth occurs in women who are: Caucasian Asian Black (African American and Afro-Caribbean) Hispanic American Indian 9. A “screening out” approach to limiting the number of cervical length measures performed would include such factors as: Race Maternal age Paternal age Past obstetric history Social disadvantage 10. What is the proposed threshold cervical length to initiate progesterone treatment? 10 mm 15 mm 20 mm 25 mm 30 mm College ID Number: Name: Address: City/State/Zip: E-mail Address: Actual time spent completing this activity (you may record up to 2 hours): CME Quiz for the Clinical Expert Series Obstet Gynecol 2014;123(6) Credit available through June 2017 Page 3 of 3