Lead
Genome
Centre
Alberta
Project Leader
Oliver Bathe
Co-Project Leader
Hans Vogel
Lead
Organization
University of
Calgary
Alberta
Vickie Baracos
Sambasivarao
Damaraju
University of
Alberta
Alberta
Cyril Frank
Derrick Rancourt
University of
Calgary
Alberta
Philip Halloran
Michael Mengel,
Bertus Eksteen
Alberta
David W ishart
Liang Li
Lorne Tyrrell
Michael Houghton
Alberta
University of
Alberta
Title of Project
Research Areas
Keywords
Methodologies and Technologies
Efficient Guidance of
Biomarkers, cancer, systemic
Cancer Therapeutics using therapy, personalized medicine
Serum Metabolomics
Metabolomics, clinical trials,
translational research
Genomic markers for
cancer cachexia and pain:
Targeted therapies to
improve quality of life and
to reduce socio-economic
burden
Genome-wide association studies,
Next Generation Sequencing,
biobanking, mutational screening,
machine learning
Cancer, cachexia, pain,
personalized therapies, genetic
predisposition, health service
utilization and cost
Prediction of Osteoarthritis Osteoarthritis, Diagnostics,
Proteomics, Metabolomics,
Progression through
Health System, Multidisciplinary, Transcriptomics, Stem Cell Biology,
Proteomics, Metabolomics Bio-partnering
Data Integrations (Systems biology),
and Transcriptomics using
Diagnostic Imaging, Health Systems
an Integrative Approach
Modeling
Precision diagnostics for a Precision molecular diagnostics;
cost-effective healthcare
inflammatory and immune
system
diseases; evidence-based costeffective personalized
healthcare; legal and ethics;
molecular data and clinical
material; health system
readiness
Metabolomic devices for
Cancer, cardiovascular disease,
companion diagnostics
diabetes, maternal health,
University of and personalized medicine diagnostics, biomarkers, kits and
Alberta
devices
University of
Alberta
Hepatitis C-New Therapies- Emerging and persistent viral
The Canadian Challenge infections, host response, viral
genomics, therapeutics
Transcriptomics, metabolomics,
advanced pathology; biostatistics;
clinical research; economic
modeling; decision analytic cost
effectiveness, machine learning;
policy development; information
systems
Metabolomics, nanotechnology,
analytical chemistry, protein
engineering, microfluids, mass
spectrometry, NMR,
chromatography
RNAi, Metabolomics, Genomic
Sequencing
Alberta
Jack Tuszynski
Sharon Marsh
University of
Alberta
Alberta
Anthony Schryvers
James Kellner
University of
Calgary
David Murray
University of
Alberta
Alberta
Matthew Parliament
Alberta
David Olson
Benedikt Hallgrimsson,
Christoph Sensen
University of
Alberta
Alberta
Christopher McCabe
Tania Bubela
University of
Alberta
Personalized cancer
treatment by optimization
of chemotherapy through
drug target profiling
cancer chemotherapy,
personalized medicine, taxanes,
vinca alkaloids,
pharmacogenomics, clinical
communication
Computational drug design, DNA
profiling, metabolomics, pre-clinical
testing, genotyping, point of care
case studies, bioinformatics
Development of Predictive
Tests of Vaccine
Outcomes Using
Microbiome, Epigenetic,
and Immunological
Analyses
immunological responses to
vaccination; host epigenetics
and microbiome; public attitudes
towards vaccination;
socioeconomic factors guiding
public vaccination programs;
Birth cohort study; immunological
response to vaccination; paediatric
microbiome and epigenome
analysis; surveys and focus groups;
socioeconomic and legal analysis of
personalized vaccination schedule.
Molecular Toolkits for
Detection, Imaging and
Treatment of Cancer
Cancer, molecular diagnostics,
treatment resistance, individual
sensitivity, genetic variants
Immunohistochemistry, DNA/RNA
sequencing, metabolomics,
molecular imaging, epigenetics
Canadian Integrated
Genomics Accessible
Resource
Single Nucleotide
Polymorphisms, Epigenetics,
maternal and child health,
circulating nucleic acids,
database legacies, gene x
environment interactions
Bioinformatics, longitudinal
developmental cohorts, rat bevioural
and developmental epigenetics,
CAN-ARIES (Canadian Accessible
Resource for Integrated
Epigenomics Studies)
PACE - 'Omics:
Personalized, Accessible,
Cost-Effective applications
of 'Omics technologies
Evidence-based cost-effective
personalized healthcare: Health
technology assessment;
resource allocation modeling;
socio-economic, legal and
ethical issues in the clinical
translation of 'omics research;
governance and regulation of
innovation and technology
Economic modeling; health
technology assessment;
comparative case study analysis;
public preference elicitation;
Bibliometrics; Patent landscaping
Alberta
Walter Maksymowych
Alberta
Luanne Metz
Marcus Koch,
Olga Kovalchuk,
Ruth Ann Marrie
University of
Alberta
Personalized Medicine
RA Biomarker for Personalized
Applications of Proteomic Medicine
Biomarkers that are
Predictive of Joint Damage
Progression in Rheumatoid
Arthritis
Omics, Biomarkers, Reduce Social
and Economic Burden of a Chronic,
Debilitative Disease, Early
Diagnosis, Prognosis, Therapy
Selection/Monitoring, Validation
Criteria Defined - OMERACT
(Internationally) Endorsed, Clinical
Applications and Commercial
Feasibility
University of
Calgary
Epigenetics of Treatment
response in Multiple
Sclerosis
Epigenetics, DNA methylation, small
RNA sequencing, gene expression,
exome sequencing
University of
Calgary
Cancer Genomics:
Cancer, copy number variation,
Diagnostic Tests for Breast circulating nucleic acids,
and Ovarian Cancer
detection
Alberta
Randal Johnston
Christoph
Sensen
Alberta
Dustin Hittel
Eric Hoffman
University of
Calgary
Multiple Sclerosis, Treatment
response, biomarkers
High throughput sequencing,
chromatin genomic hydridization,
bioinformatics, functional genomics
AIMMY:A populationHeart, Kidney, Type 2 Diabetes, Genotype-stratified intervention,
clinical trials, metabolomics
based clinical trial network Prevention, Prediction,
designed for proof of
Perception, Intervention
principle testing of
preventative genomic
medicine