University of Bradford Postgraduate Programme specification UNIVERSITY OF BRADFORD School of Life Sciences Institute of Cancer Therapeutics Programme Title: Cancer Drug Discovery Awarding and teaching institution: University of Bradford Final and interim awards: Master of Science Postgraduate Diploma Postgraduate Certificate [Framework for Higher Education Qualifications level 7] Programme title: Programme approved / accredited by: Cancer Drug Discovery N/A Relevant subject benchmark statement(s): N/A Duration: UCAS code: FHEQ Level: Date produced: Last updated : 1 year full-time N/A 7 May 2008 January 2014 Background Based upon a greater understanding of the molecular aspects of cancer progression, new opportunities for chemical intervention in this disease have emerged. Medicinal chemists provide the expertise required in translating that understanding to the identification of suitable chemical entities, and to the process of optimisation that ultimately leads to the discovery of new cancer medicines. This programme is designed to provide you with a ‘state of the art’ education in modern drug discovery, which meets the demand of employers in pharmaceutical industry. Opportunities to learn the latest innovations in drug discovery, including computer-aided drug design and techniques in parallel synthesis as well as electronic data management are provided in the programme. In addition, an extended project in drug discovery will not only provide you with first-hand experience of the challenges in original research, but also gives you an opportunity to put in practice the knowledge you have gained. For career progression within this sector a postgraduate qualification is highly desirable. For the pursuit of this type of programme, you must have a degree qualification, usually in chemical or biological sciences. The programme promotes advanced scholarship within specialised areas concomitant with the development of key transferable skills (in IT and bioinformatics) and research techniques. The programme uses a range of teaching strategies to promote independent study and research; to develop a systematic and critical understanding of the molecular basis of disease progression; and to enhance autonomous learning and personal transferable skills. This programme will facilitate the development of the skills you require for careers in academia, industry or for further research. Enhancement of your independent learning skills during the programme will equip you with the skills to succeed as lifelong learners. Programme Aims The programme is intended to: A1 Enable you to develop a systematic understanding, critical awareness, and skills in selected disciplines within the field of cancer drug discovery. A2 Provide you with a detailed knowledge of common strategies and methods for the design and discovery of new cancer medicines. A3 Provide a strong knowledge base in the theory and practical skills of synthetic organic chemistry and their application in cancer drug discovery. A4 Develop within the context of drug discovery, a comprehensive understanding of communication, research skills and scientific method. A5 Provide learning opportunities to enable you to think critically and to further develop as an autonomous and lifelong learner. A6 Further develop your ability in a range of personal and key skills. Programme Learning Outcomes On successful completion of the programme you will be able to: LO1 critically evaluate specialized areas of cancer drug discovery. LO2 critically evaluate scientific literature and communicate scientific data. LO3 critically evaluate and appraise experimental laboratory techniques with specific emphasis on those relevant for efficient preparation of pure organic compounds. LO4 implement a research project, employ appropriate experimental approaches and report your findings in relation to current knowledge and understanding. LO5 LO6 LO7 LO8 demonstrate critical thinking through an ability to independently: recognise, define and prioritise problems; analyse, interpret, objectively evaluate and prioritise information, recognising its limitations; demonstrate a conceptual understanding of research and scientific method through ability to independently: critically evaluate methodology; critically analyse and interpret data; formulate conclusions based on complete and incomplete data. critically evaluate strategies for experimental design and drug synthesis. critically analyse a therapeutic target and current therapeutic approaches to that specific target. Prepare and implement a programme of independent learning through reflective study Apply skills in time-management, oral presentation, written communication specifically by: writing and interpreting scientific reports. giving an oral scientific presentation. The Curriculum The Postgraduate Diploma is studied over two semesters, each comprising of 60 Credits studied as double (20 Credit) or linked (10+10 Credits) modules. The programme is designed as a core curriculum amounting to 40 Credits in semester 1 and 20 Credits in semester 2. A further 20 Credits in semester 1 and 40 Credits in semester 2 are studied from optional curriculum offered at ICT and other SLS departments. The Masters programme follows on from this and incorporates an additional 60 Credit research project. Learning, Teaching and Assessment Strategies A wide variety of teaching methods appropriate to the learning outcomes of the individual modules is employed throughout the programme, which is supported by Blackboard, the virtual learning environment, provided by the University. A seminar program involving external speakers, with international reputations in the field, will be established and you will have the opportunity to discuss scientific issues with them. In addition, the Institute of Cancer Therapeutics has regular internal research seminars and attendance at these is encouraged. The teaching methods focus on student-centred approaches to learning. In this way you will develop the attributes needed for life-long learning and continued professional development. All students will be supported by a dedicated Programme Tutor for the duration of the programme. Academic support is also provided by individual tutors / supervisors for the Critical Appraisal and Research Project through regular meetings for the duration of these activities. Module Code Module Title Module Credits Level Type Sem Postgraduate Certificate CR-4016D CR-4008L CR-4014L CR-4006D CR-4001D Principles of Drug Discovery Research & Analytical Methods Critical Appraisal of a Current Topic in Drug Discovery Toxicology and Safety Pharmacology Molecular Basis of Cancer & Cancer Therapy Core Core Core 20 10 10 7 7 7 1 1&2 1&2 Optional Optional 20 20 7 7 1 1 If you have achieved the regulatory credit points at Level 7 and have achieved learning outcomes LO 1-3 and 5-8, you may exit the programme and are eligible for the award of Postgraduate Certificate Postgraduate Diploma CR-4008L CR-4014L CR-4013D CR-4012D CR-4010D Research & Analytical Methods Critical Appraisal of a Current Topic in Drug Discovery Case Studies in Drug Discovery Chemical Toolbox for Drug Discovery Molecular Mechanisms of Toxicity Core Core 10 10 7 7 1&2 1&2 Optional Optional Optional 20 20 20 7 7 7 2 2 2 If you have achieved the regulatory credit points at Level 7 and have achieved learning outcomes LO 1-3 and 5-8, you may exit the programme and are eligible for the award of Postgraduate Diploma. Master of Science CR-4015Z Research Project in Drug Discovery 60 7 3 If you have achieved the regulatory credit points at Level 7 and have achieved learning outcomes LO 1-8, you are eligible for the award of Master of Science. The curriculum may change subject to the university programme approval, monitoring and review procedures. Learning outcome LO1 will be developed through a series of lectures, workshops and directed study and assessed by unseen written examination questions, critical appraisal, and course work assignments. Learning outcome LO2 will be developed and assessed by critical appraisal and course work. Acquisition of learning outcomes LO3 and LO4 will occur gradually and cumulatively through a number of modules employing a mix of lectures, investigations, workshops, individual project work and directed private study. They will be assessed by an unseen written examination using constructed-response (essay) type questions, course work, assignments, oral presentation, dissertation and project work. Directed private study will involve you in a variety of activities, which include directed reading of selected textbooks and specified source literature, Blackboard (directed Web-based materials), report writing and other assignments. The development of learning outcomes LO5 and LO6 will be through involvement in small-group seminars, laboratory investigations and individual project-based work and assessed by critical appraisal, course work, seminar paper, written assignment, oral presentation and project work. Key skills are embedded in the curriculum and some modules develop or consolidate and assess one or more of the key skills listed in learning outcomes LO7 and LO8. More detailed description of the way that learning is related to assessment in the modules that make up this programme can be found on the module descriptors. Assessment regulations This Programme conforms to the standard University Assessment Regulations for Postgraduate Programmes which are available at the following link: http://www.bradford.ac.uk/aqpo/ordinances-and-regulations/ Admission requirements The University welcomes applications from all potential students regardless of their previous academic experience; offers are made following detailed consideration of each individual application. Most important in the decision to offer a place is our assessment of a candidate’s potential to benefit from their studies and of their ability to succeed on this particular programme. Entrance requirements for each programme will vary but consideration of your application will be based on a combination of your formal academic qualifications and other relevant experience. If you have prior certificated learning or professional experience which may be equivalent to parts of this programme, the University has procedures to evaluate this learning in order to provide you with exemptions from specified modules contained within the curriculum. Please talk to us if you do not fit the standard pattern of entry qualifications. We are continually reviewing and developing our practices and policies to make the University more inclusive, but if you are disabled we may need to make some adjustments to make sure that you are not disadvantaged. We would advise you to contact the programme leader before you apply to discuss these. Up to 30 students can be admitted to the Masters programme in Drug discovery, and this may include a significant number of applicants from outside the EU. Offers are made following detailed consideration of each individual application. Most important in the decision to offer a place is our assessment of a candidate’s potential to benefit from their studies and of their ability to succeed on this particular programme. Entrance requirements will vary, but are set after consideration of each applicant’s academic background and achievements and other relevant experience. As a general guideline, acceptance on the Masters programme requires an Honours degree in chemical or biological sciences, or related disciplines. The expectation is that this would be at 2.2 classification or above. Applicants whose first language is not English will need to demonstrate proficiency in English in accordance with University Regulations. For further details, see http://www.bradford.ac.uk/international/before-you-apply/english-language-requirements/. Students with prior certificated learning or prior experiential learning may be accredited on a case by case basis by a claim for recognition of prior learning (RPL). Learning Resources The JB Priestley Library on the city campus and our specialist library in the School of Management provide a wide range of printed and electronic resources to support your studies. We offer quiet study space if you want to work on your own, and group study areas for the times when you need to discuss work with fellow students. Subject librarians for each School provide training sessions and individual guidance in finding the information you need for your assignment, and will help you organise your references properly. Student PC clusters can be found in both our libraries and elsewhere on the campus. Many of these are open 24/7. You can also use the University's wireless network to access the internet from your own laptop. Most of our journals are available online (both on and off campus), and you can also access your University email account, personal information and programme-related materials this way. Staff are on hand during the daytime to help you if you get stuck, and there is a 24/7 IT helpline available. Student Support and Guidance Programme Team Support for you personally and in your programme of study, will be provided both by the University and the Programme Team. You will be allocated a personal tutor who is someone with whom you will be able to talk about any academic or personal concerns. The School will ensure that there is someone available with whom you feel comfortable to help and support you. You will be provided with a comprehensive series of handbooks that you can consult on a range of learning issues and your programme tutors will be available to consult on subject specific queries. Students’ Union We value the feedback provided by students and collaborate with the Students’ Union, through a system of student representatives and formal staff student liaison committees, so that any issues you wish to raise are addressed rapidly. The Students Union provide professional academic representation and advice. The Students’ Union and the University of Bradford work in partnership to provide confidential counselling and welfare services where you can get help with any aspect of your personal or academic life. Student Financial and Information Services (part of the Hub) will provide you with information about a diverse range of issues such as council tax, personal safety and tourist information. International Students can access a range of additional advice and support services through the Student’s Union. Learner Development Unit for Academic Skills Advice For postgraduate students on taught programmes who are looking to improve their marks during their time at university, study skills and maths advice is available to all regardless of degree discipline. Students can access a programme of interactive workshops and clinics which is delivered throughout the year. This is in addition to our extremely popular face-to-face guidance from our advisers, who also offer a wide range of online and paper based materials for self-study. http://www.bradford.ac.uk/learner-development/ Disability Disabled students will find a supportive environment at Bradford where we are committed to ensuring that all aspects of student life are accessible to everyone. The Disability Service can help by providing support, advice and equipment to help you get the most out of your time at Bradford. It is a place where you can discuss any concerns you may have about adjustments that you may need, whether these relate to study, personal care or other issues. For more information contact the Disability Service by phoning: 01274 233739 or via email: disabilities@bradford.ac.uk University policies and initiatives Ecoversity Ecoversity is a strategic project of the University which aims to embed the principles of sustainable development into our decision-making, learning and teaching, research activities campus operations and lives of our staff and students. We do not claim to be a beacon for sustainable development but we aspire to become a leading University in this area. The facilities we create for teaching and learning, including teaching spaces, laboratories, IT labs and social spaces, will increasingly reflect our commitments to sustainable development. Staff and student participation in this initiative is crucial to its success and its inclusion in the programme specification is a clear signal that it is at the forefront of our thinking in programme development, delivery, monitoring and review. For more details see www.bradford.ac.uk/ecoversity/ Further Information: For further information, please check the University prospectus or contact Admissions. The Admissions Office The University of Bradford Richmond Road Bradford, BD7 1DP UK +44 (0)1274 233054 http://www.brad.ac.uk/courses/ The Postgraduate Admissions Tutor Institute of Cancer Therapeutics School of Life Sciences The University of Bradford Richmond Road Bradford, BD7 1DP UK +44 (0)1274 233226 http://www.cancer.brad.ac.uk/ The contents of this programme specification may change, subject to the University's regulations and programme approval, enhancement and review procedures.