Curriculum Vitae
Name: Chun-Han Hou M.D. Ph.D.
Birth: July 3rd, 1976.
Education:
1. High school: Taipei Municipal Jeng-Kuo High School
1991-1994.
2. Medical school: National Taiwan University School of Medicine, MD Degree
1994-2001.
3. Master, Graduate Institute of Clinical Medicine, Medical College, National
Taiwan University
Sep. 2004~July 2006.
4. PhD, Institute of Biomedical Engineering, National Taiwan University
Sep. 2006~ July 2009.
Position:
1. Internship, National Taiwan University Hospital
July, 2000 ~ June, 2001.
2. Residency, Department of Orthopedic Surgery of National Taiwan University
Hospital.
July, 2001 ~ Dec. 2005.
3. Chief Resident, Department of Orthopedic Surgery of National Taiwan University
Hospital.
Jan. 2005 ~ Dec. 2005.
4. Fellow, Department of Orthopedic Surgery of National Taiwan University
Hospital.
Jan. 2006 ~ July 2007.
5. Attending Physician, Department of Orthopedic Surgery of National Taiwan
University Hospital, Yun-Lin Branch.
July 2007~ Oct. 2009.
6. Adjunct Lecturer, Department of Orthopedic Surgery of National Taiwan
University Hospital. Feb 2008~Jan 2010
1
7. Attending Physician, Department of Orthopedic Surgery of National Taiwan
University Hospital Nov. 2009~ Now (CURRENT POSITION)
8. Adjunct Assistant Professor, Department of Orthopedic Surgery of Natioznal
Taiwan University Hospital. Feb 2010~Now
Honors and Awards:
1. Young Investigator’s Award in School of Medicine, National Taiwan University –
May 1999.
2.
3.
4.
5.
“ Ultrasound Examination of Patellar Tendon after Harvest for Anterior Cruciate
Ligament Reconstruction”
Best Intern Award- Oct., 2000.
By Department of Orthopedic Surgery, National Taiwan University Hospital.
Excellent Paper Award of Taiwan Orthopedic Association- Oct. 2002.
“Hospital – Based Allogenic Bone Bank- Ten Year Experience”.
Best Orthopedic Resident Award of the Year
National Taiwan University Hospital, Year 2002, 2003, 2004, and 2005.
Best Paper Award of Taiwan Orthopedic Association- Oct. 2004.
“Clinical Application of Proton MR Spectroscopy of the Femoral Head on
Patients of Osteonecrosis
6. Elite Youth Award of Taipei City
April 2006.
7. “Scholarship for Medical and Master Degree” in Academic Sinica, Taiwan
December 2006.
8. First-Place Award of Excellent Paper Competition, Taiwan Orthopaedic Research
Association, Year 2009
October 2009.
9. Elite paper Award, Taiwan Orthopaedic Association, Year 2009
October 2009.
10. International Symposium of Materials on Regenerative Medicine (ISOMRM)，
Young Investigator Award, Year 2010
November 2010.
Fellowship & Exchange programs:
1. English training course July 1997 in King’s College, UK
2
2. Exchange student of Harvard Medical School, USA, March-May 2000
-One-month clerkship in Brigham & Women’s Hospital
-One-month clerkship in Beth Israel Hospital
3. Japan visiting fellow of Year 2007, Asia Pacific Orthopedic Association (APOA),
Fukuoka, Japan, July 2007
- visiting lab
- studying Musculoskeletal oncology and spine surgery
3
Research Project
Title of Research Project
Study the role of EGF ligand in
bone disease— (I) Investigation of
EGF ligand in ICAM
Study the role of EGF ligand in
bone disease— (I) Investigation of
EGF ligand in ICAM
Role/
Position
Duration
Supporting
Institution
CoPrincipal
Investigator
Shin Kong
2013/01/01~ Wu Ho-Su
2013/12/31
Memorial
Hospital
Co-
Shin Kong
2013/01/01~ Wu Ho-Su
Principal
Investigator
2013/12/31
Memorial
Hospital
Project
Status
Amount of
Funding
Ongoing
659,280
Ongoing
600,000
Principal
Investigator
2012/01/01~ National
2012/12/31
Taiwan
University
Hospital
Ongoing
350,000
CoStudy the role of CCN3 in
osteoarthritis— (I) Investigation of Principal
Investigator
CCN3 in ICAM-1 expression in
2012/01/01~ Shin Kong
2012/12/31
Wu Ho-Su
Memorial
Ongoing
695,680
The mechanism of Benzimidazole
derivatives induces
chondrosarcoma cell apoptosis
osteoblasts
Hospital
Study the role of CCN3 in
osteoarthritis— (II) Investigation
of CCN3 in MMP-13 expression
in chondrocytes
CoPrincipal
Investigator
2012/01/01~ Shin Kong
2012/12/31
Wu Ho-Su
Memorial
Hospital
Ongoing
695,680
Fabrication of greigite and its
applications for cancer
hyperthermia
Principal
Investigator
2011/08/01~
2014/07/31
National
Science
Council
Ongoing
2,862,000
The application of biodegradable
magnetic ‘Dicalcium Phosphate
Principal
Investigator
2010/08/01~ National
2013/07/31
Science
Ongoing
3,381,000
Ongoing
3,274,000
Dihydrate’ nanoparticles as
thermoseeds for hyperthermia
cancer therapy.
Administer unit: National Taiwan
University Hospital
The anti-cancer effect of human
placenta-derived mesenchymal
stem cells and
Council
CoPrincipal
Investigator
2010/08/01~ National
2013/07/31
Science
Council
4
bone-marrow-derived
mesenchymal stem cells after
hyperthermia.
Administer unit: National Taiwan
University Hospital
The optimal strategy of the animal
model with novel HAP-based
biodegradable magnetic
nanoparticles for hyperthermia
anti-cancer therapy
Administer unit: National Taiwan
Principal
Investigator
Completed
590,000
Eastern
Memorial
Hospital)
University Hospital
A Novel HAP-based
biodegradable magnetic
nanoparticle on hyperthermia
cancer therapy
Administer unit: National Taiwan
University Hospital, Yun-Lin
2010/07/01~ National
2011/06/30
Taiwan
University
Hospital
(coopered
with Far
Principal
Investigator
2009/01/01~ National
2009/12/31
Taiwan
University
Hospital,
Yun-Lin
Branch
Completed
150,000
The study of adiponectin receptor
and its effect on chondrosarcoma
metastasis.
Administer unit: National Taiwan
University Hospital, Yun-Lin
Branch
Principal
Investigator
2009/01/01~ National
2009/12/31
Taiwan
University
Hospital,
Yun-Lin
Branch
Completed
100,000
Study of Bio-mechanisms of
Researching
staff
2008/12/01~ National
2011/12/31
Science
Council
Ongoing
CoPrincipal
Investigator
2008/01/01~ National
2008/12/31
Taiwan
University
Hospital,
Completed
Branch
Placenta-derived Multi-potent
46,720,000
Stem Cell Therapy in Diseased
Animal Models
Administer unit: National Taiwan
University Hospital
Study of the possible therapeutic
effects of ultrasound stimulation
on fracture healing-- Effects of
ultrasound stimulation on MMP-9
150,000
5
expression in osteoblasts
Yun-Lin
Administer unit: National Taiwan
University Hospital, Yun-Lin
Branch
Branch
Study of the possible therapeutic
effects of ultrasound stimulation
on degenerative joint disease-Effects of ultrasound stimulation
on iNOS expression and NO
production in chondrocytes
Administer unit: National Taiwan
CoPrincipal
Investigator
2008/01/01~ National
2008/12/31
Taiwan
University
Hospital,
Yun-Lin
Branch
Completed
300,000
Study the effects of stromal
Principal
cell-derived factor-1 in lung cancer Investigator
metastasis to bone
Administer unit: National Taiwan
University Hospital, Yun-Lin
Branch
2008/01/012008/12/31
Completed
200,000
A Novel Nd-Fe-SiO2
Researching
2007/08/01~ National
Completed
3,210,000
biodegradable magnetic bioglass
on hyperthermia cancer therapy
Administer unit: National Taiwan
University Hospital
staff
2010/07/31
The Development and Application
of a Novel Canine Modular Total
Hip Prosthesis and Implantation
System
Administer unit: School of
Veterinary Medical National
Researching
staff
2006/01/01~ National
2007/12/31
Science
Council
Completed
3,780,000
University Hospital, Yun-Lin
Branch
National
Taiwan
University
Hospital,
Yun-Lin
Branch
Science
Council
Taiwan University Hospital
6
Publication List
Refereed papers:
1.
2.
3.
4.
5.
6.
7.
8.
Sheng-Mou Hou, Chun-Han Hou. Prefabricated vascularized bone graft on
rats. Proceedings of 6th Congress of the International Federation of
Societies for Surgery of the Hand (IFSSH), 957-61, 1995.
Chun-Han Hou, Chung-Li Wang, Chi-Chang Lin. Ultrasound examination
of patellar tendon after harvest for anterior cruciate ligament reconstruction.
Journal of the Formosan Medical Association. 100(8): 315-318, 2001 May
(SCI) IF: 1.132(Medicine, General & Internal: 76/153=49.7%)
Chun-Han Hou, Chin-Hao Chang. Neuropathy in Elbow Arthroplasty.
Journal of Orthopedic Surgery Taiwan. 20(2): 58-63, 2003
Chun-Han Hou, Sheng-Mou Hou, Rong-Sen Yang. Clinical application of
proton MR spectroscopy of the femoral head in patients with osteonecrosis.
Journal of Orthopedic Surgery Taiwan. 21:153-159, 2004.
Chun-Han Hou, Rong-Sen Yang, Sheng-Mou Hou. Hospital-based
allogenic bone bank--10-year experience. Journal of Hospital Infection.
2005 Jan;59(1):41-5.(SCI) IF: 3.393 (Infectious diseases: 21/70=30%)
Pei-Yu Chen, Chen-Tu Wu, Chun-Han Hou, Sheng-Mou Hou. Loosening
of total arthroplasty with a prosthesis employing a skirted femoral head.
Journal of the Formosan Medical Association. 2005 May;104(5):370-3.
(SCI) IF: 1.132(Medicine, General & Internal: 76/153=49.7%)
Chun-Han Hou, Chieh-Yu Liu, Ying-Ding Li, Tony Enright, Tiffany
Ting-Fang Shih. Proton MR Spectroscopy of the Femoral Head ─
Evaluation of Patients at Risk for Avascular Necrosis. Journal of Magnetic
Resonance Imaging. 2006 Aug;24(2):409-17. (SCI) IF: 2.698 (Radiology,
Nuclear Medicine & Medical Imaging :34/116=29.3%)
Chun-Han Hou, Wei-Dean Wang, Kai-Kuen Leung, Sheng-Mou Hou. An
Analysis of the Practice Outcome and Opinions of Physicians from the Last
Ten Years of the Government Sponsored General Physician Training
Program. Journal of Medical Education. 2007 Mar ; 11:47-57.
9. Chun-Han Hou, Tzu-Wei Tan, Chih-Hsin Tang. AMP-activated protein
kinase is involved in COX-2 expression in response to ultrasound in
cultured osteoblasts. Cellular Signalling. 2008 May;20(5):978-88 (SCI)
IF: 4.058 (Cell biology: 67/180=37.2%)
10. Karl Wu, Chun-han Hou, Rong-sen Yang. Clinical Management Strategies
of musculoskeletal oncology. Formosan Journal of Medicine. 2008 July;
7
12(4): 408-415.
11. Chun-Han Hou, Yi-Chin Fong, Jung-Tsan Chen, Ju-Fang Liu, Min-Sheng
Lin, Chih-Shiang Chang, Chih-Hsin Tang. The novel isoflavone
7-hydroxy-3',4'-benzoisoflavone induces cell apoptosis in human
osteosarcoma cells. Cancer letters. 2008 Nov; 271(1):117-28 (SCI) IF:
4.238 (Oncology: 42/194=21.6%)
12. Chun-Han Hou, Sheng-Mou Hou, Chih-Hsin Tang. Ultrasound increased
BMP-2 expression via PI3K, Akt, c-Fos/c-Jun and AP-1 pathways in
cultured osteoblasts. Journal of Cellular Biochemistry. 2009 Jan;
106(1):7-15 (SCI) IF:2.868 (Biochemistry & Molecular Biology:
142/289=49.1%)
13. Chun-Han Hou, Yu-Chun Hsiao, Yi-Chin Fong, Chih-Hsin Tang. Bone
morphogenetic protein-2 enhances the motility of chondrosarcoma cells via
activation of matrix metalloproteinase-13. Bone. 2009 Feb;44(2):233-42
(SCI) IF: 4.023 (Endocrine & Metabolism: 34/121=28.1%)
14. Chun-Han Hou, Jinn Lin, Shier-Chieg Huang, Sheng-Mou Hou, Chih-Hsin
Tang. Ultrasound stimulates NF-κB activation and iNOS expression via the
Ras/Raf/MEK/ERK signaling pathway in cultured preosteoblasts. Journal of
Cellular Physiology. 2009 Jul;220(1):196-203. (SCI) IF: 3.874
(Physiology: 12/79=15%)
15. Chun-Han Hou, Sheng-Mou Hou, Yu-Sheng Hsueh, Jinn Lin, Hsi-Chin
Wu, Feng-Huei Lin. The in vivo performance of biomagnetic
hydroxyapatite nanoparticles in cancer hyperthermia therapy. Biomaterials.
2009 Aug; 30(23-24):3956-60. IF: 7.404 (Engineering, Biomedical:
2/72=2.7%)
16. Chun-Han Hou, Ching-Wei Chen, Sheng-Mou Hou, Yu-Ting Li,
Feng-Huei Lin. The fabrication and characterization of dicalcium phosphate
dihydrate-modified magnetic nanoparticles and their performance in
hyperthermia processes in vitro. Biomaterials. 2009 Sept; 30(27):4700-07
IF: 7.404 (Engineering, Biomedical: 2/72=2.7%)
17. Yu-Min Huang, Chun-Han Hou, Sheng-Mou Hou, Rong-Sen Yang. The
Metastasectomy and Timing of Pulmonary Metastases on the Outcome of
Osteosarcoma Patients. Clinical Medicine: Oncology 2009 Sep. 3:99-105
18. Chun-Han Hou, Rong-Sen Yang, Sheng-Mou Hou , Chih-Hsin Tang.
TNF-α increases αvβ3 integrin expression and migration in human
chondrosarcoma cells. Journal of Cellular Physiology. 2011 Mar;
226(3):792-9 (SCI) IF: 3.874 (Physiology: 12/79=15%)
19. Chun-Han Hou, Yi-Chun Chiang, Yi-Chin Fong, Chih-Hsin Tang. WISP-1
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increases MMP-2 expression and cell motility in human chondrosarcoma
cells. Biochemical Pharmacology. 2011 Jun 1;81(11):1286-95. (SCI) IF:
4.705(Pharmacology & Pharmacy:28/261=10.7%)
20. Chun-Han Hou, Yi-Chin Fong and Chih-Hsin Tang. HMGB-1 induces
IL-6 production in human synovial fibroblasts through c-Src, Akt and
NF-kB pathways. Journal of Cellular Physiology. 2011
Aug;226(8):2006-2015. (SCI) IF: 3.874 (Physiology: 12/79=15%)
21. Men-Luh Yen, Chun-Han Hou, Kai-Yen Peng, Pei-Chi Tseng, Shih-Sheng
Jiang, Chia-Tung Shun, Yao-Chang Chen, and Min-Liang Kuo. Efficient
Derivation & Concise Gene Expression Profiling of Human Embryonic
Stem Cell-Derived Mesenchymal Progenitors (EMPs). Cell Transplantation.
2011 Mar; 20:1529-1545 (SCI) IF: 6.204 (Transplantation: 1/25=4%)
22. Cheng-Ta Yang, Sheng-Mou Hou, Chun-Han Hou, Feng-Ling Lin,
Chen-Chiang Lin, Rong-Sen Yang. Does the Complication Rate and
Treatment Effect of Balloon Kyphoplasty and Vertebroplasty Differ in
Countries or Specialties of Operators? Formosan Journal of Musculoskeletal
Disorders. 2011 Aug;2(3):79-84, doi:10.1016/j.fjmd.2011.06.001
23. Chun-Han Hou, Chih-Hsin Tang, Chin-Jung Hsu, Sheng-Mon Hou* and
Ju-Fang Liu*. CCN4 induces IL-6 production through avb5 receptor, PI3K,
Akt, and NF-kB singling pathway in human synovial fibroblasts. Arthritis
Research & Therapy. 2013 Jun (SCI) IF:4.445 (RHEUMATOLOGY:
7/29=24.1%) (accepted)
Conference papers:
1. Hou SM, Hou CH: Prefabricated vascularized bone graft on rats
6th Congress of the International Federation of Societies for Surgery of the
Hand(IFSSH), Helsinki (Finland), 1995
2. Hou CH, Wang CL, Lin CC: Ultrasound examination of patellar tendon
after harvest for anterior cruciate ligament reconstruction.
42nd Annual meeting, Taiwan Orthopedic Association, 2001.
3. Hou CH, Yang RS, Hou SM: Hospital –Based Allogenic bone bank-ten-year
experience.
43rd Annual meeting, Taiwan Orthopedic Association, 2002.
4. Hou CH, Hou SM: Shoulder arthrodesis following brachial plexus injury.
45th Annual meeting, Taiwan Orthopedic Association, 2003.
5. Hou CH, Wu CD, Hou SM: Scaphoid cyst caused by crystal-induced
tenosynovitis- a case report.
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45th Annual meeting, Taiwan Orthopedic Association, 2003.
6. Hou SM, Yeh LS, Hou CH, Yang LS: Allograft Transplantation of
Extremities.
96th Annual meeting of Formosan Medical Association, 2003.
7. Hou CH, Yang RS, Hou SM: Hospital –Based Allogenic bone bank-ten-year
experience.
71st Annual meeting of American Academy of Orthopedic Surgery, 2004.
8. Hou CH, Yang RS, Hou SM: A ten-year retrospective study of allogenic
bone bank at a medical center in Taiwan.
77th Annual meeting of Japanese Orthopedics Association, 2004.
9. Hou CH, Shih TF: Clinical Application of Proton MR Spectroscopy of the
Femoral Head on Patients of Osteonecrosis.
47th Annual meeting, Taiwan Orthopedic Association, 2004.
10. SM Hou, Hou CH, TK Liu, DH Lin: Clinical outcome of
minimally-invasive hip arthroplasty.
78th Annual meeting of Japanese Orthopedics Association, 2005.
11. Hou CH, Yang RS, Mau TJ, Lung CY, Chen CC, Hou SM Comparison of
the augmentation effects of polymethyl methacrylate and cortical bone
allograft on the screw fixation strength.
13th International Symposium on Limb Salvage (ISOLS), Korea, 2005
12. Huang YM, Hou CH, Yang RS, Hou SM: The therapeutic value of
thoracotomy and timing of pulmonary metastases identification for
osteosarcoma patients.
73rd Annual meeting of American Academy of Orthopedic Surgery, 2006.
13. Hou CH, Ku YF, Yeh LS, Yang RS, Hou SM: Study of End-to-Side
Neurorrhaphy in Rat Myocutaneous Iso- and Allo-transplantation.
73rd Annual meeting of American Academy of Orthopedic Surgery, 2006.
14. Hou CH, Li YD, Liu CY, Hou SM, Yang RS, Chiang CC, Hu MH, Shih
TTF,: Proton magnetic resonance spectroscopy as a prognostic factor of
femoral head avascular necrosis
74rh Annual meeting of American Academy of Orthopedic Surgery, 2007.
15. Hou CH, Li YD, Liu CY, Hou SM, Shih TTF,: Fat Composition Change as a
Prognostic Factor of Femoral Head Avascular Necrosis ? The Clinical Value
of Proton Magnetic Resonance Spectroscopy
6th Annual meeting of Combined Orthopedic Research Society, 2007.
16. Yang CT, Hou CH, LinJ, Huang SC, Hou SM. Balloon kyphoplasty and
vertebroplasty in the management of vertebral compression fracture- a
systemic review
10
55th Annual meeting, Taiwan Orthopedic Association, 2008.
17. Hou CH, Hou SM, Shieh YS, Lin J, Wu SC, Lin FH. The application of a
novel biomagnetic nanoparticle based on hydroxyapatite for cancer
hyperthermia: an in vivo study
55th Annual meeting, Taiwan Orthopedic Association, 2008
18. Hou CH, Fong YC, Chen JT, Liu JF, Lin MS, Chang CS, Tang CH. The new
isoflavone derived, HBI, induces cell apoptosis in human osteosarcoma cells.
55th Annual meeting, Taiwan Orthopedic Association, 2008
19. Hou CH, Cheng CW, Hsu CK, Hou SM, Yang RS, Lin FH. The
performance of magnetic dicalcium phosphate dihydrate nanoparticles for
cancer hyperthermia.
56th Annual meeting, Taiwan Orthopedic Association, 2009
20. Hou CH, Hou SM, Hsueh YS, Lin J, Yang RS, Huang SC, Liu HC, Lin FH.
An in vivo study of biomagnetic hydroxyapatite-based nanoparticles for
cancer hyperthermia therapy.
American Academy of Orthopaedic Surgeons（AAOS）, 2010.
21. Hou CH, Hou SM, Hsueh YS, Lin J, Wu HC, Lin FH. The in vitro
performance of biomagnetic hydroxyapatite based nanoparticles in cancer
hyperthermia.
56th Annual Meeting of the Orthopaedic Research Society, 2010.
22. Hou CH, Chen CW, Hsu CK, Hou SM, Yang RS, Liu HC, Li YT, Lin FH.
The fabrication and characterization of dicalcium phosphate
dihydrate-modified magnetic nanoparticles and their performance in
hyperthermia processes in vitro.
56th Annual Meeting of the Orthopaedic Research Society, 2010.
23. Hou SM, Lin FH, Yang KC, Yang CT, Yang RS, Li YT, Tseng CL, Wu HC
Hou CH. The biocompatibility and in vitro performance of biomagnetic
hydroxyapatite nanoparticles for cancer hyperthermia therapy. 56th Annual
Meeting of the Orthopaedic Research Society, 2010
24. Hou CH, Hou SM, Lin FL, Lin J, Yang RS, Lin FH. The animal model of
biomagnetic hydroxyapatite-based nanoparticles in cancer hyperthermia.
7th Annual meeting of Combined Orthopedic Research Society, 2010
25. Hou CH, Hou SM, Yang CT, Yang KC, Yang RS, Lin FH. The in vitro
application of biomagnetic hydroxyapatite nanoparticles for cancer
hyperthermia therapy.
7th Annual meeting of Combined Orthopedic Research Society, 2010
26. Chen CS, Hou CH, Hou SM, Wang WC, Yang RS, Lin FH. A new
thermoseeds -dicalcium phosphate dihydrate-based magnetic nanoparticles
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and their performance in hyperthermia processes in vitro.
7th Annual meeting of Combined Orthopedic Research Society, 2010
27. Chen CS, Hou CH, Wang WC, Hou SM, Yang TH. Comparison of the
Osteogenetic differentiation Effects of Human Placenta-derived and Bone
Marrow-derived Stem Cells on Biodegradable Materials
7th Annual meeting of Combined Orthopedic Research Society, 2010
28. Hou CH. The in vivo Performance of Biomangetic Hydroxyapatite
Nanoparticles in Cancer Hyperthermia Therapy.
International Symposium Of Materials On Regenerative Medicine, 2010
29. Hou CH. Calcium phosphate-based magnetic nanoparticles as thermoseeds
for cancer hyperthermia therapy.
Regeneration Medicine Symposium on Orthopedic Material Science, 2010
30. Hou CH, Hsieh FK, Guo FS, Yang RS, Chen CS. Hyperthermia-treated
Human Placenta-derived Mesenchymal Stem Cells Induce Apoptosis of
Tumor Cells
Formosan Medical Association, 2010
31. Ting-Chun Huang, Cheng-Kuang Chen, Sheng-Mou Hou, Feng-Ling Lin,
Chun-Han Hou. The Acute Side-effect of Zolendronic Acid Treatment for
Osteoporotic Patients
IOF Regionals – 1st Asia-Pacific Osteoporosis Meeting in Singapore, 2010
32. CT Yang, SM Hou, CH Hou, FL Lin, CC Lin, RS Yang. Balloon
Kyphoplasty and Vertebroplasty in the Management of Vertebral
Compression Fracture: Does the Complication Rate and Treatment Effect
Differ in Countries or Specialties of Operators?
IOF Regionals - 1st Asia Pacific Osteoporosis Meeting, Singapore, 2010
33. Cheng-kuang Chen, Chun-Han Hou, Sheng-Mou Hou. The Management
Of Anti-platelet Therapy Before The Total Knee Arthroplasty.
58th Annual meeting, Taiwan Orthopedic Association, 2011
34. Liu, J F; Tang, C H; Hou, S M; Hou, C H. WISP-1 induces IL-6 production
in human synovial fibroblasts through PI3K, AKT and NF-κB pathways.
58th Annual Meeting of the Orthopaedic Research Society, 2012.
35. Liu, J F; Tang,C H; Hou, S M; Hou, C H. WISP-1 induces VCAM-1
expression in human synovial fibroblasts through Syk, PKCd, JNK and AP-1
pathway.
58th Annual Meeting of the Orthopaedic Research Society, 2012.
36. Hou, C H; Tang, C H; Chang, C S; Hou,S M; Liu J F.
1-Benzyl-2-phenylbenzimidazole, a benzimidazole derivative, triggers
chondrosarcoma cell apoptosis via caspase-dependent and independent
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pathways.
58th Annual Meeting of the Orthopaedic Research Society, 2012.
37. Jia-Zhe Li, Chun-Han Hou. Image-Guided Calf muscle Biopsy as a Method
in Diagnosing Sarcoidosis: Review and a Case Report.
63rd Annual meeting, Taiwan Orthopaedic Association, 2012
38. Shu-Hao Chang, Chun-Han Hou. The longterm safety and adverse effect of
zoledronic acid in osteoporotic patients.
63rd Annual meeting, Taiwan Orthopaedic Association, 2012
39. De-Kai Xu, Chun-Han Hou. Primary diffuse large B cell lymphoma over
femoral supracondyle on an 80-year-old woman : case report and literature
review.
63rd Annual meeting, Taiwan Orthopaedic Association, 2012
40. Shu-Hao Chang, Chun-Han Hou. The acute phase reaction of zoledronic acid
in Asian population: a Taiwan case series.
The 2012 Annual Meeting of The Taiwanese Osteoporosis Association &
2012 IOF/ISCD FRAX Initiatives in Asia-Pacific Region
41. Shu-Hao Chang, Chun-Han Hou. The unusual adverse reaction after second
zoledronic acid injection in Taiwanese osteoporotic patients.
3rd Asia- Pacific Osteoporosis Meeting, 2012
Invited Speeches (Special or Keynote Lectures):
1. Chun-Han Hou, Rong-Sen Yang. Bone bank: our ten-year experience.
Taiwan Regenerative Medicine Society, 2009 Annual meeting
2. Chun-Han Hou. The animal model of cancer hyperthermia with magnetic
nanoparticles.
Animal oncology and pathology meeting, Taiwan, 2009.
3. Chun-han Hou. “The anti-tumor effect of human mesenchymal stem cells
(MSCs) after hyperthermia. “ (Symposium)
103rd Annual meeting of Formosa Medical Association, 2010
4. Hou CH. Hyperthermia-treated Human Mesenchymal Stem Cells induce
Apoptosis of Tumor Cells.
The 4th Pan Pacific Symposium on Stem Cells Research, 2011
Other publications:
1. Chun-Han Hou：The past, present and future of proton magnetic resonance
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spectroscopy- and its application on femoral head avascular necrosis.
Taiwan Orthopedic Research Society Communication, July 2006
2. Chun-Han Hou： Proton Magnetic Resonance Spectroscopy ─ Evaluation
of lipid Composition and Assessment of Avascular Necrosis of the Femoral
Head.
Master thesis, Graduate Institute of Clinical Medicine, Medical College,
National Taiwan University
3. Chun-Han Hou ： Calcium Phosphate-Based Magnetic Nanoparticles as
Thermoseeds for Cancer Hyperthermia Therapy
Doctoral Dissertation, Institute of Biomedical Engineering, College of
Medicine and College of Engineering, National Taiwan University
4. Chun-Han Hou：Bone Density Measurement, Health word, Vol.413, p52-55,
May,2010
Research Interest：
1.
2.
3.
4.
Metabolic bone disease, including osteonecrosis of femoral head.
Orthopedic oncology.
Hyperthermia cancer therapy
Musculoskeletal ultrasound.
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