Dispatcher Recognition of cardiac arrest Author(s): Christian Vaillancourt, Manya Charette, Mike Smyth Date: 06 November 2014 Question: Among adults and children who are in cardiac arrest outside of a hospital (P), does the description of any specific symptoms to the dispatcher (I), compared with the absence of any specific description (C), change increase the likelihood of cardiac arrest recognition (O)? Settings: Out of hospital Bibliography: Studies added since 2010 Deakin, C; Evans, S; King, P. Evaluation of telephone-cardiopulmonary resuscitation advice for paediatric cardiac arrest. Resuscitation 2010; 81 (7): 853-6. Clawson, J; Barron, T; Scott, G; Siriwardena, N; Patterson, B; Olola, C. Medical Priority Dispatch System breathing problems protocol key question combinations are associated with patient acuity. Prehosp Disaster Med 2012; 27 (4): 375-80. Tanaka, Y; Taniguchi, J; Wato, Y; Yoshida, Y; Inaba, H. The continuous quality improvement project for telephone-assisted instruction of cardiopulmonary resuscitation increased the incidence of bystander CPR and improved the outcomes of out-of-hospital cardiac arrests. Resuscitation 2012; 83 (10): 1235-41. Lewis, M; Stubbs, B; Eisenberg, M. Dispatcher-assisted cardiopulmonary resuscitation: time to identify cardiac arrest and deliver chest compression instructions. Circulation 2013; 128 (14): 1522-30. Weiser, C; van Tulder, R; Stöckl, M; Schober, A; Herkner, H; Chwojka, C; Hopfgartner, A; Novosad, H; Schreiber, W; Sterz, F; Dispatchers impression plus Medical Priority Dispatch System reduced dispatch centre times in cases of out of hospital cardiac arrest. Pre-alert--a prospective, cluster randomized trial. Resuscitation 2013; 84 (7): 883-8. Stipulante, S; Tubes, R; Fassi, M; Donneau, A; Van Troyen, B; Hartstein, G; D'Orio, V; Ghuysen, Al. Implementation of the ALERT algorithm, a new dispatcher-assisted telephone cardiopulmonary resuscitation protocol, in non-Advanced Medical Priority Dispatch System (AMPDS) Emergency Medical Services centres. Resuscitation 2014; 85 (2):177-81. Dami, F; Fuchs, V; Praz, L; Vader, J. Introducing systematic dispatcher-assisted cardiopulmonary resuscitation (telephone-CPR) in a non-Advanced Medical Priority Dispatch System (AMPDS): implementation process and costs. Resuscitation 2010; 81 (7): 848-52. Bång, A; Herlitz, J; Martinell, S. Interaction between emergency medical dispatcher and caller in suspected out-of-hospital cardiac arrest calls with focus on agonal breathing. A review of 100 tape recordings of true cardiac arrest cases. Resuscitation 2003; 56 (1): 25-34. 2010 studies included: Bohm, K; Stålhandske, B; Rosenqvist, M; Ulfvarson, J; Hollenberg, J; Svensson, L. Tuition of emergency medical dispatchers in the recognition of agonal respiration increases the use of telephone assisted CPR. Resuscitation 2009; 80 (9): 1025-8. Clawson, J; Olola, C; Scott, G; Heward, A; Patterson, B. Effect of a Medical Priority Dispatch System key question addition in the seizure/convulsion/fitting protocol to improve recognition of ineffective (agonal) breathing. Resuscitation 2008; 79 (2): 257-64. Eisenberg, M; Hallstrom, A; Carter, W; Cummins, R; Bergner, L; Pierce, J. Emergency CPR instruction via telephone. Am J Public Health 1985; 75 (1): 47-50. Heward, A; Damiani, M; Hartley-Sharpe, C. Does the use of the Advanced Medical Priority Dispatch System affect cardiac arrest detection? Emerg Med J 2004; 21 (1): 115-8. Roppolo, L; Westfall, A; Pepe, P; Nobel, L; Cowan, J; Kay, J; Idris, A. Dispatcher assessments for agonal breathing improve detection of cardiac arrest. Resuscitation 2009; 80 (7): 769-772. Vaillancourt, C; Verma, A; Trickett, J; Crete, D; Beaudoin, T; Nesbitt, L; Wells, G; Stiell, I. Evaluating the effectiveness of dispatch-assisted cardiopulmonary resuscitation instructions. Acad Emerg Med 2007; 14 (10): 877-83. Bång, A; Biber, B; Isaksson, L; Lindqvist, J; Herlitz, J. Evaluation of dispatcher-assisted cardiopulmonary resuscitation. Eur J Emerg Med 1999; 6 (3): 175-83. Bohm, K; Rosenqvist, M; Hollenberg, J; Biber, B; Engerström, L; Svensson, L. Dispatcher-assisted telephone-guided cardiopulmonary resuscitation: an underused lifesaving system. Eur J Emerg Med 2007; 14 (5): 256-9. Cairns, K J; Hamilton, A J; Marshall, A H; Moore, M J; Adgey, A A J; Kee, F. The obstacles to maximising the impact of public access defibrillation: an assessment of the dispatch mechanism for out-of-hospital cardiac arrest. Heart 2008; 94 (3): 349-53. Castrén, M; Kuisma, M; Serlachius, J; Skrifvars, M. Do health care professionals report sudden cardiac arrest better than laymen? Resuscitation 2001; 51 (3): 265-8. Clark, J; Culley, L; Eisenberg, M; Henwood, D. Accuracy of determining cardiac arrest by emergency medical dispatchers. Ann Emerg Med 1994; 23 (5): 1022-6. Hallstrom, A; Cobb, L; Johnson, E; Copass, M. Dispatcher assisted CPR: Implementation and potential benefit. A 12-year study. Resuscitation 2003; 57 (2): 123-129. Hauff, S; Rea, T; Culley, L; Kerry, F; Becker, L; Eisenberg, M. Factors Impeding Dispatcher-Assisted Telephone Cardiopulmonary Resuscitation. Ann Emerg Med 2003; 42 (6): 731-737. Nurmi, J; Pettilä, V; Biber, B; Kuisma, M; Komulainen, R; Castrén, M. Effect of protocol compliance to cardiac arrest identification by emergency medical dispatchers. Resuscitation 2006; 70 (3): 463-9. Flynn, J; Archer, F; Morgans, A. Sensitivity and specificity of the medical priority dispatch system in detecting cardiac arrest emergency calls in Melbourne. Prehosp Disaster Med 2006; 21 (2): 72-6. Garza, A; Gratton, M;Chen, J; Carlson, B. The accuracy of predicting cardiac arrest by emergency medical services dispatchers: The calling party effect. Acad Emerg Med 2003; 10 (9): 955-960. Kuisma, M; Boyd, J; Väyrynen, T; Repo, J; Nousila-Wiik, M; Holmström, P. Emergency call processing and survival from out-of-hospital ventricular fibrillation. Resuscitation 2005; 67 (1): 89-93. Ma, M; Lu, T; Ng, J; Lin, C; Chiang, W; Ko, P; Shih, F; Huang, C; Hsiung, K; Chen, S; Chen, W. Evaluation of emergency medical dispatch in out-of-hospital cardiac arrest in Taipei. Resuscitation 2007; 73 (2): 236-45. Berdowski, J; Beekhuis, F; Zwinderman, A; Tijssen, J; Koster, R. Importance of the first link: description and recognition of an out-of-hospital cardiac arrest in an emergency call. Circulation 2009; 119 (15): 2096-102. 2010 studies excluded: Eisenberg, M; Carter, W; Hallstrom, A; Cummins, R; Litwin, P; Hearne, T. Identification of cardiac arrest by emergency dispatchers. Am J Emerg Med 1986; 4 (4): 299301. [contains very little of use regarding identification of cardiac arrest beyond reporting that if patient is over 50 and caller is emotional then there is a higher probability of cardiac arrest] Bobrow, B; Zuercher, M; Ewy, G; Clark, L; Chikani, V; Donahue, D; Sanders, A; Hilwig, R; Berg, R; Kern, K. Gasping during cardiac arrest in humans is frequent and associated with improved survival. Circulation 2008; 118 (24): 2550-4. [paper addresses incidence of gasping, does not address identification of cardiac arrest] Clawson, J; Olola, C; Heward, A; Patterson, B; Scott, G. Profile of emergency medical dispatch calls for breathing problems within the medical priority dispatch system protocol. Prehosp Disaster Med 2008; 23 (5): 412-9. [paper addresses call prioritisation of breathing problems, does not seek to identify cardiac arrest only to determine if high dispatch priority was assigned] Clawson, J; Olola C; Heward, A; Patterson, B. Cardiac arrest predictability in seizure patients based on emergency medical dispatcher identification of previous seizure or epilepsy history. Resuscitation 2007; 75: 298-304. [paper addresses whether querying callers about prior history of seizure can help predict cardiac arrest, but does not report on cardiac arrest recognition] Quality assessment № of patients Impact № of studies Study design Risk of bias Inconsistency Indirectness not serious very serious 1 Imprecision Other considerations intervention control none 103/256 pre-alerts 98/262 pre-alerts Quality Importance ⨁◯◯◯ VERY LOW CRITICAL ⨁◯◯◯ VERY LOW CRITICAL ⨁◯◯◯ VERY LOW CRITICAL ⨁◯◯◯ VERY LOW CRITICAL Dispatcher recognition of cardiac arrest 1 3 Randomised trial (cluster) Before-After (observational studies) 5 Before-after (observational studies) 9 Prospective (observational studies) not serious serious not serious serious very serious 6 not serious not serious serious not serious very serious very serious 2 not serious 3 3 serious very serious none 4 7 none none After Before 2312/3108 (74.4%) 1780/3000 (59.3%) After Before 512/8275 (61.9%) 296/5885 (50.3%) 4,357 Weiser (2013) Compared “gut feeling”: MPDS code not actual patient status. Gut feeling correct 40% (pre-alert days) and 37% (non-pre-alert days). Words "dead" & "is dead" seemed to help dispatchers recognize CA more quickly. Relative Risk: 1.08 (95% CI, 0.87 to 1.33) Absolute Difference: 2.8% (95% CI, -5.5% to 11.1%) Three studies investigated the impact of additional education for dispatchers: Bohm (2009) education on agonal breathing; increase in provision of T-CPR from 47% to 68%; T-CPR with agonal breathing present 23% before training vs. 56% after; Relative Risk: 1.44 (95% CI, 1.09 to 1.91); Absolute Difference: 21.1% (95% CI, 5.4% to 35.4%) Roppolo (2009) education on agonal breathing; missed cases decreased from 28% to 18.8% following education; agonal breathing described as slow, barely breathing, noisy, gurgling, gasping; timing of breathing allowed dispatchers to identify additional cases; Relative Risk: 1.13 (95% CI, 1.05 to 1.21); Absolute Difference: 9.26% (95% CI, 3.72% to 14.51%) Tanaka (2012) education on agonal breathing, emesis and seizure; cases where T-CPR not attempted decreased following education 44% v. 26%, as did preventable factors where T-CPR not offered 25% v. 12%; Relative Risk: 1.30 (95% CI, 1.25 to 1.36); Absolute Difference: 17.16% (95% CI, 14.53 to 19.76) Five studies investigated the impact of scripted protocols, or additions to scripted protocols: Heward (2004) recognition increased from 15 to 50% (actual numbers not reported) Eisenberg (1985) Bystander CPR: 45% (before) v. 56%; Relative Risk: 4.32 (95% CI, 2.67 to 6.98); Absolute Difference: 29.53% (95% CI, 21.98% to 36.45%) Vaillancourt (2007); sensitivity: 56.3%; agonal respiration accounted for 50% of non-identified CA (after) (no data on recognition in before group) Clawson (2008); new question added to seizure protocol; 53% high acuity to 77%; increased provision of T-CPR; Relative Risk: 1.47 (95% CI, 1.16 to 1.84); Absolute Difference: 24.65% (95% CI, 10.65% to 37.51%) Stipulante (2014); recognition decreased from 81.5% to 74.8%; rates of T-CPR increased; Relative Risk: 1.09 (95% CI, 1.00 to 1.19); Absolute Difference: 6.63% (-0.02% to 13.14%) Focus of questioning on consciousness (is patient awake, can they be awakened) and breathing pattern (is patient breathing, breathing normally, listen to breathing over phone, count breaths).Recognition was reported in a variety of ways. We have attempted to group by outcome below. Quality assessment № of patients Impact № of studies Study design Risk of bias Inconsistency Indirectness Imprecision Other considerations intervention Quality Importance ⨁◯◯◯ VERY LOW CRITICAL control Sensitivity: Sensitivity was reported in one study as 68.9% (Cairns, 2008). Cardiac Arrest Recognition: Recognition was reported or could be calculated in six studies (Bohm, 2007; Bång, 2003; Dami, 2010; Hallstrom, 2003; Nurmi, 2006; Castrén, 2001) and ranged from 18% (Bång, 2003) to 83% (Nurmi, 2006). Noteworthy: 1. Presence of agonal breathing was reported as a potential issue in cardiac arrest recognition in four studies (Bohm, 2007; Bång, 2003; Dami, 2010; Nurmi, 2006). Bohm (2007) reported that CPR was offered to 23% with signs of breathing vs. 92% described as not breathing. Only 4/38 patients with abnormal breathing were offered T-CPR in Bång (2003). Dami (2010) reported 21 cases of unrecognized OHCA where the bystander reported normal breathing. In the Nurmi (2006) paper, the identification rate was 80% when there was abnormal breathing vs. 83% overall. 2. There is evidence from two studies (Dami, 2010; Hallstrom 2003) to indicate that cardiac arrest recognition decreases when the protocol is not followed. Dami (2010) reported 60 unrecognized cases (20.4%) because protocol questions about consciousness and breathing were not asked. Hallstrom (2003) reported protocol deviations in 69% of unrecognized cases vs. 5.3% of recognized cases. 3. Bång (2003) reported an incidence of agonal breathing of ~30% and noted the following descriptors: difficulty, poorly, gasping, wheezing, impaired, occasional breathing. Cardiac arrest recognition was reported heterogeneously across the studies. We have grouped the studies below by the outcome used. 8 Retrospective (observational studies) very serious 6 not serious very serious 3 very serious 7 none 3,417 Sensitivity: Sensitivity was reported in four studies (Deakin, 2010; Flynn, 2006; Garza, 2003; Ma, 2007) and ranged from 68.3% (Garza, 2003) to 96.9% (Ma, 2007). Specificity: Specificity was reported in two studies and exceeded 99% in both (Deakin, 2010; Flynn, 2006). Cardiac Arrest Recognition: Cardiac arrest recognition was reported or could be calculated in three studies (Deakin, 2010; Lewis, 2013; Kuisma, 2005) and ranged from 45.2% (Deakin, 2010) to 80% (Lewis, 2013). Noteworthy: The presence of agonal breathing was reported to decrease cardiac arrest recognition in two studies (Lewis, 2013; Hauff, 2003). Lewis (2012) reported recognition of cardiac arrest increases if a dispatcher is able to assess consciousness and breathing. Quality assessment № of studies Study design Case control (observational study) 1 1. 2. 3. 4. 5. 6. 7. 8. 9. Risk of bias serious 8 Inconsistency not serious № of patients Indirectness not serious Imprecision very serious 9 Other considerations none intervention Impact Quality Importance Berdowski (2009) EMDs to ask about consciousness and breathing. Recognition: 71.2%; sensitivity: 71% (95% CI, 0.67-0.75) Failure to ID CA 42/82 calls did not ask about breathing, 16/82 did not ask about type of breathing. Trigger words: "is dead", "not breathing", "abnormal breathing". Facial colour "blue", "gray" or "pale" highly associated with CA. "Abnormal breathing" desrcibed as "occasional breathing, barely/hardly breathing, heavy breathing, laboured or noisy breathing, sighing, strange breathing". ⨁◯◯◯ VERY LOW CRITICAL control 285 cases (confirmed and suspected CA) 9230 controls Matches to MPDS dispatch code, does not address patients in cardiac arrest Large number of cases excluded for 'technical reason' without adequate explanation. Pre-alert not performed in 480/736 cases – no assessment of accuracy in cases where no pre-alert was performed Several of the studies were concerned with outcomes post introduction of t-CPR, primary intention not to identify factors associated with recognition of cardiac arrest. Several studies with small number of participants limiting accuracy. One study reported outcomes by percentage only and did not present actual numbers. The denominator for the After group for Vaillancourt 2007 does not include 42 eligible cases for which there was no recording. There is no information available on cardiac arrest recognition for the 295 cases from the Before group, so they were not included in the denominator. Majority of studies suffer methodologic flaws Several studies with small numbers, some with many excluded cases Confounding not adequately controlled for Sample reported as 9230 confirmed not cardiac arrest, but this is based on sample of 506 cases