Name: ___________________________ Period: _________ Date: ________________ Ms. Hartnett Chapter 5, Lessons 4 & 5 HUMAN INHERITANCE What are the Functions of the Sex Chromosomes? Body cells of humans have 23 chromosome pairs, or 46 chromosomes The sex chromosomes are the 23rd pair of chromosomes Sex chromosomes carry genes that determine a person’s sex as being either male or female Sometimes, other genes are on these chromosomes too Girl or Boy? Sex chromosomes are the only pair that don’t always match Girls have two sex chromosomes that do match These are called X chromosomes Boys have two chromosomes that don’t match They have an X chromosome and a Y chromosome The Y is much smaller than the X Sex Chromosomes and Fertilization All egg cells carry one X chromosome Sperm cells can carry either an X or a Y If the sperm that fertilizes the egg has an X chromosome, the egg will then have two X chromosomes Egg will develop into a girl If the sperm that fertilizes the egg has a Y chromosome, the egg will have an X and a Y Egg will develop into a boy Sex-Linked Genes Some genes are carried on sex chromosomes Sex-linked genes = alleles are passed from parent to child on sex chromosomes Remember: the Y chromosome is much smaller than the X chromosome This means they will have different genes Sex-linked genes also have dominant and recessive alleles A dominant allele on an X chromosome will hide a recessive allele on the other X chromosome But for males, there isn’t a matching allele on the Y chromosome to hide the X chromosome allele Any allele on the X chromosome will produce a trait in a male who inherits it Inheritance of Colorblindness Colorblindness = a trait controlled by a recessive allele on X chromosome Many more males than females have red-green colorblindness This is because females can carry the recessive trait and not express it Carrier = person who has one recessive allele and one dominant allele The carrier can pass on the recessive trait ADVANCES IN GENETICS How Can Organisms Be Produced with Desirable Traits? Everyone’s DNA is different DNA can show us how families are related and how we can make organisms with desirable traits Three methods for developing organisms: 1. Selective breeding 2. Cloning 3. Genetic engineering 1. Selective Breeding Selective breeding = process of selecting organisms with desired traits to be parents of the next generation Anyone have cows, goats, or farms? Which traits do you choose? Two ways to selectively breed: 1. Inbreeding 2. Hybridization Inbreeding Inbreeding = crossing two individuals that have similar desirable characteristics Crossing two golden retrievers that are both friendly and have the same coloring This produces organisms that are very similar This type of selective breeding also increases the chance of getting two recessive alleles Can lead to genetic disorders like cancer Hybridization Hybridization = breeders cross two genetically different individuals Hybrid organism that results is likely to have the best traits from both parents A farmer might cross corn that produces many kernels with corn that is resistant to disease The farmer is hoping to get corn that produces many kernels and is resistant to disease 2. Cloning Clone = organism that has exactly the same genes as the organism it came from Bacteria and plants are much easier to clone than animals For plants: cut the stem from one plant, put it in soil, soon you’ll have a brand new plant that is identical to the first one 3. Genetic Engineering Genetic engineering = genes from one organism are transferred into the DNA of another organism This can produce medicines and improve food crops Genetic Engineering in Bacteria Some bacteria can be genetically engineered to produce a human protein called insulin This is for people with diabetes and need insulin shots Scientists just insert the gene for insulin into the DNA of the bacteria and the bacteria will start making insulin Gene Therapy Someday we might be able to use genetic engineering to correct genetic disorders in humans Gene therapy = inserting copies of a gene directly into a person’s cells