Test 4 Review Chapters 12 - 15 Chapter 12 • Mitosis Stages • Parts of the chromosome – Centromere – center of chromosome – Centrosome – in the cell – Kinetochore – proteins that spindle fibers attach to…all around the chromosome • Cyclin, kinase activity, cell cycle • What is the difference between a cell that is haploid and a cell that is diploid? • Which cells in the body would be haploid and which would be diploid? • How are chromatids and homologous chromosomes different? Chapter 13 • Meiosis • Sex determination • SRY gene • Why are Mendel’s laws of segregation and independent assortment important? • When does crossing over occur and why is it important? What is it called when the separation of chromosomes does not occur properly? Chapter 14 & 15 • Genetics • Punnet squares • Pedigrees • • • • X inactivation Linked genes Chromosome problems Genomic Imprinting • If a scientists crosses a homozygous tall plant with a homozygous short plant, what will be the genotype and phenotype ratio for the F1 and F2 generation? • You inherit a race horse and decide to put him to stud. In looking over the stud book, however, you discover that the horse’s grandfather exhibited a rare disorder that causes brittle bones. The disorder is hereditary and results from homozygosity for a recessive allele. If your horse is heterozygous for the allele, it will not be possible to use him for stud because the genetic defect may be passed on. How might you determine whether your horse carries the allele? • Four babies are born in a hospital, and each has a different blood type: A, B, AB, O. • The parents of these babies have the following pairs of bloog types: – A and B – O and O – AB and O – B and B • Which baby belongs to which parents?