CRSS 8871: Genome Analysis and Comparative Genomics
Introduction:
This 1-credit hour course introduces graduate students to the methodologies used in
genetic mapping, genome analyses and comparative genomics. The material is presented
as formal lectures and is enhanced by hands-on mapping exercises. You will learn how
to construct a genetic map, conduct comparative analysis at the map and DNA sequence
level, and become conversant with the cutting-edge technologies that exist in genome
analysis. Key papers related to genetic mapping will be discussed in an accompanying 1credit hour Graduate Seminar class (PBIO 8820)..
All academic work must meet the standards contained in ‘A Culture of Honesty’.
Students are responsible for informing themselves about those standards before
performing any academic work. The link to more detailed information about academic
honesty can be found at: http://www.uga.edu/ovpi/honesty/acadhon.htm
Instructor:
Katrien M. Devos
Office: Miller Plant Sciences Bldg. Rm. 4107
Phone: 542-0925
Email: kdevos@uga.edu
Office hours:
Drop-in’s will be accommodated whenever possible, but better to make an appointment
Miscellaneous:
When: Spring 2014, Weeks 6-10.
Class times: Wednesdays from 11.05 am – 12.20 pm and Fridays from 11.05 am –
12.20 pm (class times are chosen to accommodate, where possible, registered
students)
Where: Miller Plant Sciences Bldg., Rm 1503
Grading:
A-F
60% on class participation and class/home work (includes final Jeopardy quiz)
40% on final exam (take-home)
Tentative schedule
Wedn 12th February:
Fri 14th February:
Wedn 19th February:
Fri 21st February:
Wedn 26th February:
Fri 28th February:
Wedn 5th March:
Fri 7th March:
Markers: Lecture
Markers (cont.): Lecture
Mapping: Lecture
Practical exercise: using Mapmaker to construct a linkage map
Practical exercise: using Mapmaker to construct a linkage map
Map-based cloning: Lecture
Map-based cloning: Lecture
Comparative genomics: Lecture
Wedn 12th March & Fri 14th March: Spring Break
Wedn 19th March:
Discussion of mapping issues
Fri 23rd March:
Jeopardy – Questions related to the course
For Mapmaker practice:
Please download Mapmaker from:
http://www.plantbio.uga.edu/~russell/index.php?s=1&n=5&r=0
The information given in class pertains to the PC version of Mapmaker
There is a Mapmaker version available for Macs; commands may vary from PC version
Please bring your lap tops with Mapmaker installed to class