1 Recall the Phases of the Cell Cycle Phase Interphase Stage G1 S G2 Mitotic Phase Mitosis cytokinesis Description Growth and cellular functions; organelle replication Growth and chromosome replication; organelle replication Preparation for cell division Division of nucleus Division of cytoplasm to give 2 daughter cells Recall the 4 Phases of Mitosis Phase Prophase Metaphase Anaphase Telophase Description DNA condenses; spindle fibers begin to form Chromosomes line up in a single file at the middle of the cell Sister chromatids separate and pull to opposite sides Nuclear membrane reforms, chromosomes unwind 2 CHAPTER 4 REPRODUCTION OF ORGANISMS LESSON 1 – SEXUAL REPRODUCTION AND MEIOSIS What is Sexual Reproduction? Observation - The individual kittens in a litter can have different colors. Reason – Sexual reproduction In sexual reproduction the genetic material (DNA) from two different cells combine, producing an offspring. Sex cells are required. The female sex cell is called an egg (ovum). The male sex cell is a sperm. Fertilization is the joining of an egg cell and a sperm cell. Fertilization produces a new cell called a zygote. In a litter of 4 kittens, each kitten began as a zygote. Each zygote had its own combination of genes in its DNA. 3 Diploid Cells Multicellular organisms that undergo sexual reproduction have two general types of cells. Diploid cells are the great majority of the cells – body cells. (Somatic Cells) Diploid cells have pairs of chromosomes. Chromosomes in Diploid Cells Recall – DNA coiled up forms a chromosome. A duplicated chromosome has two sister chromatids joined by the centromere. Page 118 shows matched pairs of chromosomes. These are the homologous pairs in a human diploid cell: 4 Pairs of chromosomes that have genes for the same traits arranged in the same order are called homologous chromosomes. Each organism has a particular number of chromosomes, and half of the number of homologous pairs. (p. 118) o One chromosome in a pair is inherited from the mother, and the other from the father. 5 Humans have 23 pairs of chromosomes in diploid cells (body cells). o If the number of chromosomes is different, there are problems. o Down syndrome occurs when there is an extra copy of chromosome 21. o For a male, the last pair is an X chromosome and a Y chromosome. For a female, the last pair is two X (long) chromosomes. Haploid Cells Sex cells are haploid cells. Haploid cells are cells that have only one chromosome from each pair. 6 To produce the haploid cells, a special cell division called meiosis takes place. In meiosis, one diploid cell divides and makes four haploid cells. Meiosis occurs only during the formation of sex cells. How do diploid cells differ from haploid cells? Comparison of Mitosis and Meiosis Mitosis One cell divides once to produce 2 identical daughter cells. The daughter cells have the same number of chromosomes as the original cell. All the cells are diploid. Meiosis One reproductive cell divides twice to produce 4 haploid cells. The 4 haploid cells have half the number of chromosomes as the original cell. The four cells are sex cells for reproduction. 7 Before Meiosis A reproductive cell goes through the interphase. Duplicated chromosomes – two sister chromatids joined by a centromere – are produced. Summary of Meiosis (pages 120 – 121) Meiosis I The Division of One Diploid Cell into Two Cells Stage of Meiosis Description I Prophase I Nuclear membrane breaks apart. Homologous chromosomes come together and form pairs. Metaphase I Homologous chromosome pairs line up along at the middle of the cell. Spindle fibers attach to the chromosomes. Anaphase I Chromosome pairs separate and are pulled to opposite ends of the cell. Sister chromatids stay together. Telophase I Nuclear membrane forms around each set of duplicated chromosomes. Cytoplasm divides 8 during cytokinesis, forming two daughter cells. Meiosis II The Division of Two Cells into Four Haploid Cells Stage of Meiosis II Prophase II Metaphase II Anaphase II Telophase II Description Nuclear membrane breaks apart within each cell. Sister chromatids line up at the center of the cells. Sister chromatids of each duplicated chromosome begin to separate and are pulled to opposite ends of the cells. A nuclear membrane forms around each set of chromatids (again called chromosomes). With cytokinesis the cytoplasm of the 2 cells divides, giving 4 haploid cells. Advantages of Sexual Reproduction It gives genetic variation. Selective breeding is possible. Organisms with desired traits are chosen and bred. 9 Disadvantages of Sexual Reproduction Takes time and energy What You Must Know About Mitosis and Meiosis Mitosis Begins with one diploid cell – a body cell Has 4 phases – prophase, metaphase, anaphase, telophase After mitosis, the cell divides in two (by cytokinesis) to give 2 identical daughter cells that are diploid. Meiosis It begins with one reproductive cell that is diploid. o The cell contains duplicated chromosomes. A duplicated chromosome has two identical sister chromatids joined by a centromere. o The duplicated chromosomes are found in pairs called homologous chromosomes. 10 Each duplicated chromosome in the pair has genes for the same traits arranged in the same order. The original reproductive cell undergoes meiosis I with these phases: o prophase I, metaphase I, anaphase I, telophase I This gives two daughter cells. o Each daughter cell has half the number of chromosomes as the original cell. o The chromosomes are duplicated chromosomes. The two daughter cells undergo meiosis II with these phases: o prophase II, metaphase II, anaphase II, telophase II This gives 4 new cells. o The new cells are haploid, having half the chromosomes of the original reproductive cell. 11 o The chromosomes are chromatids. Reason: during anaphase II the sister chromatids of each duplicated chromosome are separated.