1 Student’s Name: Morgan Whitmore Unit:DT8 Date: 4-5-2011 History/Physical and Summary of Hospitalization Init. RMcC Age 72 years old Gender male Rm. # 65-2 Ethnicity Caucasian Admit Date 4-1-2011 Admitting Diagnosis Chemotherapy for recurrent Primary CNS lymphoma. Past Medical History (This should include information on any other medical problems the pt. may have such as heart disease, diabetes, HTN, etc. as identified in physician's H&P, progress, consultations and medications.) Patient has a history of benign paroxysmal positional vertigo, bilateral sensorineural hearing loss, lymphoma of central nervous system, removal of prostate, pulmonary embolism, and craniotomy tumor. History of Current Illness/Injury (What precipitated this hospitalization): Patient had last round of chemotherapy 3/11-3-18. He is back for his continuation of chemotherapy treatment to treat his recurring CNS lymphoma. Vital Sign Trends for Previous 24 hours: T max. 36.3-36.5 P 6-71 R 14-18 BP 132/80-160/90 O2 Sat 95-97 Intake last 24/hrs 6,023.5 mL Output last 24/hrs 4,475 mL Wt today 70.7 Kg; Wt yesterdays 70.7 Admit wt 70.217 Kg, Braden scale score 21; Fall risk score 35 Abnormal Physical Assessment findings: (Use Prep day data) Patient was very nauseated and vomited frequently. Nursing Care: Activity: as desired Nutrition/Route: regular diet DVT Prophylaxis: continuous alternating leg pressure devices Type of IV / IV solution: NS 0.9% 20 mL/hour continuous Pulmonary Care/Airway: pulse oximetry with vital signs Code Status: Full Code Tubes/Drains: None Allergies: Dilantin/Phenytonin Sodium, Contrast Dye, Heparin Agents Wound Care: None Special Precautions: None Misc: Vital signs every 4 hours, methotrexate lab values every 12 hours, weigh daily Nursing Diagnoses: 1. Risk for imbalanced nutrition related to chemotherapy. 2. Risk for infection related to chemotherapy. 3. Risk for fluid overload related to chemotherapy. 2 Laboratory Results Explanations Lab Test Decreased potassium Decreased BUN Decreased glucose Increased glucose Decreased calcium Decreased protein Increased AST Increased ALT Decreased WBC Significance/Explanation As It Relates to Your Patient He is on chemotherapy, he has had nausea and vomiting due to the chemotherapy which decreases one’s potassium levels. This is decreased because his protein is decreased related to his chemotherapy. This indicates the patient’s malnutrition. He has cancer therefore is on chemotherapy – which decreased the patient’s appetite. Stress, medications, and his illness caused her glucose to increase. Patient has a decreased appetite related to chemotherapy. Patient’s appetite and oral intake are decreased due to chemotherapy. Patient is on chemotherapy. Patient is on chemotherapy. WBC’s decreased due to the patient being on chemotherapy. Nursing Diagnoses 1. Risk for infection related to chemotherapy 2. Risk for malnutrition related to chemotherapy 3 Nursing Implications: Drug: Generic Name Trade Name Sennosides (Senokot) Drug Class / Mechanism of Action Laxative Senna alters water and electrolyte transport into large intestine causing increased peristalsis Leucovorin Folinic Acid Antidotes for methotrexate Vitamins Normal Dosage Range Frequency 12-50 mg/day; once or twice daily 200 mg followed by 370 mg fluorouracil Docusate (Colace) Laxative/stool softener Adds water into the stool and electrolytes and water into the colon Current Prescribed Dosage / Time / Route Why is your patient taking this medication? 17.2 mg tablet Daily at bedtime oral He may become constipated from decreased nutritional intake and chemotherapy. Diarrhea Cramping Nausea 200 mg every three hours Minimize hematologic effects of high doses of methotrexate therapy Thrombocytosis IV increase dose according to parameters. Reduces form of folic acid that serves as a cofactor in the synthesis of DNA and RNA. 50-400 mg/day in 1 -4 doses three most common side effects 100 mg Twice daily Oral Nursing Diagnoses List one nursing diadiagnosis for each memedication Drug effectiveness: How will you know if the drug is working for the your patient? Interactions with other meds? Risk for constipation related to chemotherapy. He has a bowel movement Risk for imbalanced nutrition. Patient’s lab values are within normal ranges and patient doesn’t develop complications related to methotrexate. Risk of constipation related to chemotherapy. He has a bowel movement. Many decrease absorption of other oral drugs because of decrease transit time Allergic reactionsRash/wheezing/ Urticaria Be careful with barbiturates, alcohol, sulfamethoxazole, fluorouracil. He may be constipated from chemotherapy. Throat irritation Mild craps Rashes No drug to drug interaction 4 Bisacodyl Laxative (Dulcolax) Stimulates peristalsis by changing fluid and electrolyte transport to go to the colon Sodium Bicarbonate 5-15 mg in a single dose 10 mg= 2 tablets 30 mg/day max Daily at 1300 Anti-ulcer agent Antiemetic Zofran Blocks effects of serotonin and the chemoreceptor trigger zone in the CNS. Abdominal cramps Nausea Risk of constipation related to chemotherapy. He has a bowel movement Cramping Orally Be cautious with antacids, histamine H-2 receptor antagonists, gastric acid-pump inhibitors, may decrease absorption of oral drugs because of increase motility and decreased transit time. 2-5 mEq/kg Acts as an alkalinizing agent by releasing bicarbonate ions. Following oral administration releases bicarbonate which is capable of neutralizing gastric acid. Ondansetron In case he becomes constipated. 0.15 mg/kg 15-30 minutes prior to chemotherapy. Repeat four and 8 hours later= 32 mg/day 150 mEq D5W 1,000 mL 200 mL/hour IV Continuous To decrease his risk of developing a ulcer from chemotherapy. Also used to alkaline urine due to his chemotherapy. Metabolic alkalosis Hypocalcemia Hypokalemia 4 mg every 6 hours PRN In case he has nausea or vomits. Headache IV push over 2 minutes Risk for excess fluid volume. Patient doesn’t develop an ulcer. Urine is within normal lab ranges for alkaline. Risk for constipation. Patient doesn’t develop nausea and vomiting. Salicylate or barbiturates may have decreased effects, increases blood levels of quinidine, mexiletine, flecainide, amphetamines. Constipation Diarrhea May affect drugs altering the activity of the liver enzymes. 5 Reglan Antiemetic Metoclopramide Blocks dopamine receptors in chemoreceptor trigger zone. Stimulates motility of the upper GI tract and accelerates gastric emptying. NaCl 0.9% Acetaminophen Tylenol Mineral and electrolyte replacements and supplements Sodium is a major cation in extracellular fluid and helps maintain water distribution ,fluid, acid base balance, osmotic pressure, and electrolyte balance. Chloride is a major anion in extracellulr fluid and used in maintaining acid base balance. Antipyretic Non-opioid analgesics Inhibits the synthesis of prostaglandins hat my serve as mediators of pain and fever. 10-20 mg four times daily 10 mg tablet four times daily IV Push every six hours PRN He is having chemotherapy and has nausea and vomiting. Drowsiness Restlessness Risk for imbalanced nutrition. Patient doesn’t develop nausea and vomiting and maintains an healthy weight, with electrolytes in normal ranges. Patient’s electrolyte and mineral lab values are within desired limits. Neuroleptic malignant syndrome Additive CNS depression with other CNS depressants. May increase absorption and risk of toxicity from cyclosporine. 1 Liter contains 150 mEq sodim/L Rate and amount determined by condition being treated 20 mL/hour from 1,000 mL bag Continuous IV He is in the hospital for chemotherapy having a continuous IV helps keep him hydrate and his electrolytes balanced. Congestive heart failure Pulmonary edema Hypervolemia Risk for deficient fluid volume. 1 gram 3-4 times daily 650 mg tablet every 4 hours PRN Oral In case he experiences mild pain. Hepatic failure Neutropenia Rash Risk for pain. May increase risk of bleeding with warfarin. Concurrent use of sulfinpyrazone and barbiturates may increase liver Risk for excessive fluid volume. Patient doesn’t develop pain or pain is tolerable. 6 Aluminum and Magnesium Hydroxide DBL Str with Simethicone Maalox Max Liquid Hydrocodone/Acetaminophen Vicodin Lorazepam Ativan Anti-ulcer agent Neutralizes gastric acid following dissolution in gastric content. Inactivates pepsin if pH is raised to greater or equal to 4. Opioid analgesic Binds to opiate receptors in the CNS. Alters perception of painful stimuli while producing generalized CNS depression. Sedative/hypnotic Anti-anxiety Benzodiazepines Depresses the CNS by potentiating GABA. Magnesium Sulfate Mineral and electrolyte replacement Essential for many enzyme activities. 5-30 mL 2.5-10 mg every 3-6 hours PRN 15 mL every 6 hours PRN Oral 5 mg/500 mg= 1-2 tablets every 6 hours PRN Oral In case he experiences indigestion, help prevent him from developing an ulcer related to his nausea and vomiting from the chemotherapy. For moderate to severe pain. damage, concurrent use of NSAIDS increase the risk of adverse renal effects. Constipation Diarrhea Hypomagnesaemia Absorption of tetracyclines, itraconazole, iron salts may be decreased. Hypotension Constipation Sedation Risk for imbalanced nutrition related to chemotherapy. Patient doesn’t develop an ulcer and his electrolyte labs remain stable. Risk for pain related to lymphoma. Patient’s pain levels are controlled or no pain is experienced. Risk for injury related to Ativan’s side effects. Patient doesn’t develop nausea and vomiting, nausea and vomiting are reduced, patient doesn’t injury self. Risk for injury. Patient doesn’t injury himself. Patient’s lab values increase. Be careful with MAO inhibitors, antihistamines, and sedative/hypnotics. 2 mg 30 minutes prior to chemotherapy Repeated every 4 hours PRN 0.5-1 mg every 4 hours PRN IV 1 gram every 6 hours for 4 doses or 250 mg/kg over 4 hours 2 grams PRN IV For breakthrough nausea and vomiting For hypomagnesaemia Dizziness Drowsiness Apnea Levodopa may have decreased efficacy, valproate can increase serum concentrations, additive with other CNS depressants. Drowsiness Diarrhea Arrhythmias May potentiate calcium channel blockers and neuromuscular blocking agents. 7 Potassium Chloride Mineral and electrolyte replacement 10-20 mEq/dose max 40 mEq/dose 10 mEq IV PRN For hypokalemia Maintains acid base balance and electrophysiological balance of the cell. Activates many enzyme reactions, helps with muscle contraction, tissue synthesis, and carbohydrate metabolism. Prochlorperazine Compazine Zolpidem Ambien Antiemetic Alters the effects of dopamine in the CNS. Possess significant anticholinergic and alpha adrenergic blocking activity. Depresses chemoreceptor trigger zone in the CNS. Sedative/hypnotic Produces CNS depression by binding to GABA receptors. 5-10 mg- can repeat once Arrhythmias Confusion Paralysis Imbalanced nutrition. Used with potassium sparing diuretics or ace inhibitors or angiotensin 11 may lead to hyperkalemia. 5-10 mg every 6 hours PRN IV push For nausea and vomiting Constipation Dry mouth Blurred vision Risk for deficient fluid volume. Patient doesn’t develop worsening of nausea and vomiting. Patient states he is not nauseated or vomited. Risk for ineffective sleep patterns. Patient is able to sleep through the night. Patient isn’t tired during the day. Additive hypotension with antihypertensive, nitrates, or alcohol. Antacids may decrease absorption. 10 mg at bedtime 5 mg tablet daily at bedtime Oral For insomnia Daytime drowsiness Dizziness Anaphylactic reactions Increased CNS depression with use of additional sedatives, alcohol, opioids, tricyclic’s. Patient doesn’t develop hyperkalemia. Lab values increase into normal ranges. 8 Critical Assessment Cardiovascular: Assess BP, heart tones, capillary refill, pulses Respiratory: Assess breath sounds, oxygen saturation, encourage ambulation, deep breathing, and coughing Immune- trend WBC labs, assess for signs of infection/SIRS/Sepsis- VS frequently and trend them Skeletal- assess movement and strength Integument- Assess for pressure ulcers, dry, warm, intact, assess IV site Neurological- assess pain level, LOC, assess for dizziness Digestive- assess nausea, vomiting, electrolyte labs and trend them, assess abdomen- look, listen, and palpate, assess last bowel movement. Endocrine- trend blood glucose levels Urinary- assess input and output Reproductive - N/A Assessment of Knowledge Deficit: Patient’s knowledge deficit related to importance of nutrition as evidenced by patient’s decreased appetite from chemotherapy. Outcomes/Evaluation Parameter: Patient verbalizes importance of nutrition for healing and decreasing risks for complications. Patient’s intake of nutrition increases and is adequate for discharge. Patient drinks adequate fluids. Patient identifies foods he can tolerate. Patient understands importance of food pyramid and how it applies to him. Planning and intervention with rationale: Weigh the patient daily and trend results. Encourage food and fluids. Teach patient about nutrition, food pyramid, and risks related to his personal nutrition. Diagnosis: Chemotherapy for reoccurring CNS Lymphoma Secondary Dx: History of pulmonary embolism, positional vertigo, bilateral sensoineural hearing loss, removal of prostate, and craniotomy tumor. Critical Assessments: See Above List of all actual and potential physiological and psychosocial nursing diagnosis: Risk for infection, imbalanced nutrition, imbalanced electrolytes, risk for deficient fluid volume knowledge deficit regarding discharge needs, Risk for impaired gas exchange, risk for sexual dysfunction, risk for ineffective coping, risk for caregiver role strain, , impaired urinary elimination. : Nursing Diagnosis with assessment parameters Risk for infection related to Chemotherapy. Outcomes/Evaluation Parameter: Patient doesn’t develop an infection. Patient can verbalize sign and symptoms of infection. Vital signs are stable. Patient verbalizes how he will protect himself from unnecessary germs in the environment. Patient’s skin remains intact. Planning and intervention with rationale: Teach patient signs and symptoms of infection. Teach patient how to protect himself in the environment from germs. Monitor vital signs for SIRS/sepsis, trend lab reports- WBCs. Nursing Diagnosis with assessment parameters Imbalanced electrolytes related to chemotherapy as evidenced by patient’s decreased potassium and calcium. Outcomes/Evaluation Parameter: Patient doesn’t develop cardiac complications related to decreased potassium levels. Patient’s lab values increase into normal ranges. Patient no longer needs supplements. Patient is able to eat meals without vomiting. Patient verbalizes signs and symptoms of myocardial infarction. Planning and intervention with rationale: Provide electrolyte supplements according to MD’s orders. Trend electrolyte labs, provide nausea medication before meals so that electrolytes increase through his diet. Patient’s heart remain stablesmonitor VS and regular EKG assessments. Teach patient signs and symptoms of myocardial infarction. Assessment of Discharge Planning needs: Patient’s vital signs, hemodynamics, and labs 9 are stable. Patient doesn’t develop complications from chemotherapy. Patient no longer vomiting or it decreases. Electrolytes are increased and supplements are no longer needed. Patient completes chemotherapy. Outcomes/Evaluation Parameter: Patient verbalizes understanding on medications and side effects. Patient’s vital signs and labs are stable. Planning and intervention with rationale: Trend patient lab values and assess for imbalance electrolytes and infection. Administer medications according to MD’s orders. Teach patient about medications and side effects about discharge medications. Nursing Diagnosis with assessment parameters Imbalanced nutrition related to chemotherapy as evidenced by patient’s decrease appetite, emesis, and skipping meals. Outcomes/Evaluation Parameter: Patient is able to tolerate meals without vomiting. Patient eats 75% of meals. Patient’s fluid intake is adequate. Patient no longer needs nausea medication or only takes oral nausea medication. Lab values are stable. Planning and intervention with rationale: Encourage eating and drinking fluids throughout the shift. Assess frequently for nausea and vomiting, administer nausea medication according to MD’s orders. Trend patient’s lab values. Call for dietitian consult-advocate for Ensure or another type of calories. Nursing Diagnosis with assessment parameters Risk for deficient fluid volume related to chemotherapy. Outcomes/Evaluation Parameter: Patient doesn’t develop dehydration. Patient’s body and oral fluids are adequate. Patient doesn’t display any physical signs of deficit fluid volume. Patient’s urine is 30 mL/hour. Patient’s vomiting decreased or is no longer a concern. Patient’s blood pressure remains stable Patient’s urine pH is within normal range. Planning and intervention with rationale: Encourage patient to drink fluids. Patient’ Administer IV solutions according to MD’s orders. Assess skin, mucous membranes, and LOC. Assess urine output hourly and document amounts. Assess urine pH due to chemotherapy. Measure emesis and document amounts. Assess and record blood pressures. 10