Schuab 4:00, L07 TREATING PROSTATE CANCER: CAN WE TRUST ROBOTICS IN SURGERY? Thomas Skamai (tjs85@pitt.edu) prostate and surrounding tissues. Although there are benefits and deficits to either method, I have found that the laparoscopic method is not the wisest choice. Laparoscopic prostatectomies are a poor choice due to the long term side effects after surgery. I fear that some patients are unaware of the risk that they are putting themselves into when they choose this method over the open surgery. Who is to blame for this: the engineer and/or the surgeon? Before we start pointing fingers, it is imperative for you to gain a greater understanding of the issue. A RISK CLOSE TO HOME About a month ago, my family threw a surprise birthday party for my father. He reached a milestone as he turned a whopping sixty years old. The day was filled with family, friends, laughter, dancing, hugs, cake, presents, good times, and worry. Yes, it was filled with worry. There is always concern for the health of your loved ones; and as age increases, poor health almost seems inevitable. With my father now sixty years of age, one concern really conquers my mind: prostate cancer. Family history and genetics are a factor that can put men at risk for prostate cancer [1], which is frightening since my grandpa is a survivor of prostate cancer. Also, 1 in 6 men are affected by prostate cancer (1 in 15 for ages 60 to 69) [1]. One study estimated that by the end of 2012 there will be over 28,000 deaths from prostate cancer in the United States [2]. With so many reasons to worry, I knew there must be a glimpse of hope to cling on to. I found this hope when I researched the treatment methods for prostate cancer. PROSTATECTOMY: OPEN SURGERY vs. LAPAROSCOPIC As previously stated, a prostatectomy is a surgery in which the prostate gland is removed along with some tissue around it. Open surgery is the more customary route to take for a prostatectomy. The incision can be made in one of two places, depending on the situation. One is the lower belly, and the other is the perineum between the anus and the scrotum. The more modern way to perform a prostatectomy is through laparoscopic surgery, which is also known as minimally invasive surgery. This form uses many small incisions to reach and remove the prostate [3]. Recently, the use of robotics in laparoscopic surgery is increasing. Prostate Cancer: Treatment Techniques Prostate cancer is very treatable when it is detected before it spreads outside the prostate. The most common procedure in this scenario is a radical prostatectomy, an operation to remove the prostate gland and some of the tissue around it [3]. Open and laparoscopic surgeries are the two methods used to complete a radical prostatectomy. Open surgery involves a larger incision while laparoscopic uses many smaller incisions and, at times, the help of a da Vinci surgical robot. Using either an electrical or a mechanical engineering degree, I wish to eventually work with medical equipment. I could end up striving to improve surgical robots that perform radical prostatectomies. However, first I must question if there is any value in working with these particular surgical robots. In an attempt to ease my mind and determine my possible career, I went on a search for this answer, and my discoveries were abundant. I realized how complicated matters are in engineering fields. I was reminded of the purpose behind all the work I have been putting into school. And most importantly, I discovered that both open and laparoscopic methods are known to be very effective in removing the cancerous The da Vinci Surgical System A common robot used in laparoscopic prostatectomies is the da Vinci surgical robot. In this scheme, the surgery is executed by a surgeon who sits at a console separate from the patient and controls every move of the robot. The main parts of the system are a cart for the patient, a console for the surgeon, a high-definition 3D vision system, and four robotic arms equipped with “EndoWrist” instruments. “EndoWrist” technology provides many advantages. Their range of motion is superior to a human wrist. Clamping, suturing, manipulating tissue, and other surgical movements can be done by respective “EndoWrist” instruments. University of Pittsburgh, Swanson School of Engineering Oct. 9th, 2012 1 Thomas Skamai Within the first 30 days after surgery, men who had laparoscopic surgery were more likely to report problems with genital or urinary functions. The erectile dysfunction and incontinence rates remained heavier from laparoscopic patients even after 18 months [4]. The rate of genital or urinary complications is twice as frequent in laparoscopic surgery as it is with open surgery [9]. This is an astonishing rate. Yet, some doctors do not seem to notice it; and this is where ethical concerns come into play. FIGURE 1, “ENDOWRIST” INSTRUMENTS These instruments are a diverse and vital part in the da Vinci system [7]. WHO IS BEING UNETHICAL? Many men choose laparoscopic surgeries that include the use of robots, and then suffer the consequences of their decision. The first question that comes to mind is whether or not the patients knew about the differences in risks between the two options. If they did know the consequences and chose the laparoscopic surgery anyway, then neither engineer nor doctor was being unethical. But, if the patient was never aware of the heightened risks with the laparoscopic surgery, then someone made a mistake. These arms are controlled by a surgeon who sits behind a console near the patient. The doctor’s surgical vision is provided by an endoscope, a flexible tube with a camera and light at the tip. This tool gathers the visual display of the area under operation and displays it on a high-definition 3D screen for the surgeon. This image is also shown on a large widescreen display for the rest of the operating room to see [8]. The Engineer did it! Comparing the Basics Blame the engineer, right? It’s the easy thing to do. After all, we’re just a bunch of arrogant nerds that always play on our computers and don’t have any real friends; so few are hurt when we take the fall. First of all, the previous statement is not true. Second, the engineer is not to blame in this situation. I thoroughly read the “Code of Ethics for Engineers” from the National Society of Professional Engineers [10] as well as “A Code of Ethics for Robotics Engineers” [11]. Neither document held any evidence that engineers were at fault for the sufferings of men who were treated by a laparoscopic prostatectomy. At first glance, I thought the robotics engineer may have done wrong. The code of ethics for robotics engineering states, “As an ethical robotics engineer, I understand I have the responsibility to keep in mind at all times… the expectations and the safety of the customer”[11]. I thought that if these robots are causing harm to the patients, then the engineer should have done a better job to eliminate that. The reason the engineer is NOT at fault is because these troubles cannot be controlled by the engineer. Their job was to create a machine that removes the prostate with reasonable safety, which they did. Therefore, the engineers of these surgical robots did not cross any ethical boundaries. My feeling of innocence toward the engineer was confirmed by the National Society of Professional Engineers’ code of ethics. Part of this code stated that “engineers shall avoid the use of statements containing a material misrepresentation of fact” [10]. Through all of While the goal of either prostatectomy process is the same, the two options differ in numerous ways. On average, three nights are spent in the hospital after an open prostatectomy as compared to two for laparoscopic [4]. A laparoscopic procedure consists of five small incisions that are 5 to 10 millimeters long, whereas open consists of one incision that is 4 to 5 inches long [5, 6]. This incision size is significant since it is directly related to the amount of blood loss during surgery. As expected, the small incisions combine for less blood loss opposed to the one large incision. On the other hand, due to the locations of the small incisions, they often cause problems that can be more unfavorable for the patient than blood loss. Later portions of this paper contain more detail on this matter. Last, open surgery usually implements traditional tools and laparoscopic uses modern surgical technologies such as the da Vinci robotic system. The Laparoscopic Downfall Nowadays, people tend to be attracted to modern technology. This makes it easy for somebody to miss the drawbacks that take place when fresh technology is used for laparoscopic surgery. The problems that occur after either method of a prostatectomy are fairly similar. Typical complications are difficulties getting erections, involuntary urination, internal scarring, damage to the urethra, or damage to the rectum [4, 3]. The point that people seem to be over-looking when debating the two types of surgeries is the frequency of glitches. 2 Thomas Skamai my research on surgical robots used for laparoscopic prostatectomies, I did not see any claims from the companies that mentioned a lowered risk of erectile dysfunction or urinary incontinence. The problems lie within the method itself, not the tools used to complete it. Hence, the engineer did no wrong. If I were offered a job in the area of surgical robotics, there is a decent chance I would accept it. With how much room this region has for improvement, it would be very exciting to have the opportunity to contribute to future success. Nonetheless, at the moment I do not trust surgical robots for prostatectomies. They cause too many long lasting problems. Surgeons must enlighten their patients of the facts in order to help them avoid making a choice that will have a negative impact on the rest of their lives. Ignorant Doctors If men choose laparoscopic prostatectomies without knowing all of the risks, the doctors are at fault. According to the College of Physicians and Surgeons of New Brunswick’s code of ethics, surgeons acknowledge the responsibility to “provide [their] patients with the information they need to make informed decisions about their medical care” [12]. I was unable to find statistics of the number of men who fully knew the long term risks of laparoscopic prostatectomy before they picked that method. Thus, I am unable to definitively state that the surgeon broke ethical guidelines when their patients had laparoscopic prostatectomies. If the surgeon informed the patient of the severity of risks, then the surgeon followed the code of ethics. On the contrary, if the patient was never informed of the increased potential for malfunctions after surgery (which is what I suspect), then the surgeon broke the code of ethics. Molding For the final portion of this assignment, I was instructed to assess the educational value of my task. When I first heard of this, I was excited. I was finally given the opportunity to inform the engineering department of how “stupid” this assignment was. Then, I really started to think about everything I have gained through this assignment. Sure, I learned a lot about prostatectomies, but that was not the most beneficial part. This assignment taught me how complicated the engineering field is outside the aspects of the actual product. I realized that many things must be considered, such as cost, efficacy, demand, and ethics, among others. This assignment inspired me. During the grind of this semester my focus has become selfish. I have only been concerned about getting the next assignment done, doing decent on the upcoming test, etc. Now I’ve been reminded of the reason I am here: to help others by fulfilling my potential in life. This paper made me consider the fact that my efforts today will set me up with the opportunity to positively impact society in the future; and that is a great source of motivation. I absolutely recommend that this assignment be a part of the future freshman engineering curriculums here at the University of Pittsburgh and in engineering schools around the world. I will admit that I feel sorry for the future freshman that must complete it, because it was brutal. However, students truly benefit from assignments like this. Two of the course goals listed on the Swanson School of Engineering webpage are “to introduce [students] to what engineering is” and “introduce [students] to required library research skills and communication skills used by all engineers”[13]. I strongly believe that this assignment took a big step toward fulfilling these objectives. This is encouraging, since I am finally noticing evidence that I am being molded into the person and engineer that I dream to be. CONCLUSION: THE CHOICE IS CLEAR It is unnecessary to go into detail about how sexual or urinary problems would distress a man. We all understand that this would be horrific. And if you cannot relate, please take my word for it. These problems would be incredibly depressing. When all the factors are taken into consideration, the choice between open and laparoscopic surgery is obvious. The temporal sufferings are definitely less for laparoscopic surgery. The hospital stay is shorter and the pain is less among other minor benefits. On the other hand, the long lasting effects of laparoscopic surgery are more likely to be detrimental. If men know they have a greater chance to avoid long term erectile dysfunction and urinary incontinence, their choice will be easy to predict. Open surgery is clearly the best choice of methods for prostatectomies. This procedure can be trusted to cure a man and return him to his “manly” stature. Hypothetically Speaking… If I had to make the choice between an open or laparoscopic prostatectomy, I have no doubt that I would choose open. The benefits simply do not outweigh the deficits. I refuse to be deceived by how “great” this modern da Vinci system is. 3 Thomas Skamai http://www.engineering.pitt.edu/Freshman/ENGR_0011/F all_2012/Layouts/Course_Objectives/ REFERENCES [1] (2012). “Prostate Cancer Risk Factors.” Prostate Cancer Foundation. (Online article). http://www.pcf.org/site/c.leJRIROrEpH/b.5802027/k.D27 1/Prostate_Cancer_Risk_Factors.htm [2] (2012). Cancer Facts and Figures. Atlanta, GA: American Cancer Society. (Online book). p. 6. http://www.cancer.org/acs/groups/content/@epidemiolog ysurveilance/documents/document/acspc-031941.pdf [3] C. Nickel. G. Thompson. (2010). “Radical Prostatectomy.” WebMD. (Online article). http://www.webmd.com/prostate-cancer/radicalprostatectomy-operation [4] (2009). “Robotic prostate surgery comes with tradeoff.” NBC NEWS. (Online article). http://www.msnbc.msn.com/id/33291388/ns/healthcancer/t/robotic-prostate-surgery-comes-tradeoff/#.UGu1YE070WI [5] J. Zatzkin. (2011) “Prostate Cancer: Laparoscopic Prostate Surgery”. WebMD. (Online article). http://www.webmd.com/prostate-cancer/laparoscopicprostate-surgery [6] W. See. (2009). “Open Prostatectomy.” Medical College of Wisconsin. (Online Article). http://www.froedtert.com/SpecialtyAreas/ProstateCanc erProgram/ProgramsAndServices/OpenProstatectomy.ht m [7] (2012). “Cardiac Surgery in the Age of IT.” Hospitalmanagement.net. (Online Photo). http://www.hospitalmanagement.net/features/feature1067 10/feature106710-3.html [8] (2012). “The da Vinci Surgical System”. Intuitive Surgical. (Online article). http://www.intuitivesurgical.com/products/davinci_surgic al_system/#components [9] P. Peck. (2009) “Shorter Hospital Stays but More ED with Robotic Prostatectomy”. MedPage Today. (Online article). http://www.medpagetoday.com/Urology/ProstateCancer/1 6406 [10](2003). “Code of Ethics for Engineers”. National Society of Professional Engineers. (Online article). http://www.mtengineers.org/pd/NSPECodeofEthics.pdf [11]B. Ingram. D. Jones. A. Lewis. M. Richards. C. Rich. L. Schachterle. (2010). ”A Code of Ethics for Robotics Engineers”. Worcester Polytechnic Institute. (Online article). http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=054 53245 [12] “Code of Ethics”. College of Physicians and Surgeons of New Brunswick. (Online article). http://www.cpsnb.org/english/code-of-ethics.html [13] (2012). “Course Objectives”. Swanson School of Engineering. (Online article). ACKNOWLEDGMENTS First and foremost I would like to acknowledge my parents. They have sacrificed so much for me throughout the years. I would like to thank Dr. Schuab for the constant motivation he provides. Last, but certainly not least, I would like to thank my excellent writing instructor, Janine Carlock, for generously giving her time and advice in order to improve my writing skills. 4