PARTNERSHIP HEALTHPLAN OF CALIFORNIA GUIDELINE/ PROCEDURE Guideline/Procedure Number: MPXG5002 (previously XG100502) Guideline/Procedure Title: Clinical Practice Guidelines for Diabetes Mellitus Original Date: 04/19/2000 – Medi-Cal 04/21/2010 – Healthy Kids Lead Department: Health Services ☒External Policy ☐ Internal Policy Next Review Date: 06/18/2015 Last Review Date: 06/18/2014 Applies to: ☒ Medi-Cal ☒ Healthy Kids ☐ Employees Reviewing Entities: ☒ IQI ☐P&T ☒ QUAC ☐ OPERATIONS ☐ EXECUTIVE ☐ COMPLIANCE ☐ DEPARTMENT ☐ BOARD ☐ COMPLIANCE ☐ FINANCE ☒ PAC ☐ CREDENTIALING ☐ DEPT. DIRECTOR/OFFICER Approving Entities: ☐ CEO ☐ COO Approval Signature: Robert Moore, MD, MPH Approval Date: 06/18/2014 I. RELATED POLICIES: A. N/A II. IMPACTED DEPTS: A. .. III. DEFINITIONS: A. N/A IV. ATTACHMENTS: A. N/A V. PURPOSE: Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels. (Diabetes Care, January 2012; 35(Supplement 1) VI. GUIDELINE / PROCEDURE: A. KEY POINTS IN DIAGNOSIS AND MANAGEMENT 1. Diagnosis Criteria for the diagnosis of diabetes a. A1C> 6.5%;or b. Fasting plasma glucose > 126 mg/ dL; or c. 2-h plasma glucose > 200 mg/dL during an oral glucose tolerance test d. In a patient with classic symptoms of hyperglycemia or hyperglycemic crisis, a random plasma glucose > 200 mg/dL; e. In the absence of unequivocal hyperglycemia, the result should be confirmed by repeat testing 2. Treatment. The glycemic goal in adults is the lowering of Hemoglobin A1C to below or around 7%, with the exception of patients with limited life expectancy, repeated episodes of severe hypoglycemia, advanced cardiovascular disease, advanced kidney disease and advanced neuropathy, for whom the goal is between 7-8%. The principles of treatment consist of lifestyle changes (physical activity, nutrition, smoking cessation), pharmacotherapy, appropriate weight loss, diabetes self-management education, depression screening, management of co-morbidities (hypertension, dyslipidemia), screening for and treatment of complications of diabetes (CHD, nephropathy, retinopathy, neuropathy, foot care) Page 1 of 2 Guideline/Procedure Number: MPXG5002 (previously Lead Department: Health Services XG100502) ☒ External Policy Guideline/Procedure Title: Clinical Practice Guidelines for Diabetes Mellitus ☐ Internal Policy Original Date: 04/19/2000 – Medi-Cal Next Review Date: 06/18/2015 04/21/2010 – Healthy Kids Last Review Date: 06/18/2014 Applies to: ☒ Medi-Cal ☒ Healthy Kids ☐ Employees B. PHC FORMULARY AND MEDICATIONS 1. Oral Hypoglycemics; a. Formulary -No TAR required; glimepiride (Amaryl), tolbutamide (Orinase), glyburide (Micronase, DiaBeta), glipizide (Glucotrol), metformin (Glucophage, Glucophage XR), acarbose (Precose), nateglinide (Starlix), miglitol (Glyset) b. Formulary – STEP required; alogliptin (Nesina), Alogliptin-metformin ( Kazano), linagliptin (Tradjenta), linagliptin-metformin (Jentadueto),rosiglitazone (Avandia), rosiglitazone/glimepiride (Avandaryl), saxagliptin (Onglyza), saxagliptin-metformin (Kombiglyze XR), sitagliptin (Januvia), sitagliptin/metformin (Janumet, Janumet XR), pioglitazone (Actos), pioglitazone/metformin (Actoplus Met), pioglitazone/glimepiride (Duetact), 2. Insulin; Insulin (vials), Insulin (PFS, Pen, or CRT), Insulin Pump C. INDICATORS MONITORED BY PHC: These indicators will be monitored for measurement of adherence to this guideline. 1. Quality Improvement Program for 2014-2015 a. A1C testing b. LDL testing c. Retinal eye exam d. A1C good control (< 9%) e. Blood pressure< 140/90 f. Nephropathy screening test or evidence of nephropathy VII. REFERENCES: A. PHC has adopted the diabetes guidelines entitled American Diabetes Association Clinical Practice Recommendations published in Diabetes Care, January 2014; 37(Supplement 1). A copy of the guideline is available at http://care.diabetesjournals.org/content/37/Supplement_1/S1.full.pdf+html VIII. DISTRIBUTION: A. HS Department UM Staff B. PHC Provider and Practitioner Manuals C. PHC Department Directors IX. POSITION RESPONSIBLE FOR IMPLEMENTING PROCEDURE: X. REVISION DATES: Medi-Cal 12/19/01; 09/18/02; 09/15/04; 11/17/04; 03/21/07; 04/21/10; 06/20/12; 06/18/14 Healthy Kids 06/20/12; 06/18/14 PREVIOUSLY APPLIED TO: PartnershipAdvantage MPXG5002 - 03/21/2007 to 01/01/2015 Healthy Families MPXG5002 - 05/18/2007 to 03/01/2013 Page 2 of 2