Proposed Data Element Query Parameters for Basic DAF over DIRECT Use Case Submitted by Stephen Beller on 7/12/14 – updated 7/31/14, 8/5/14 I attended the 7/9/14 Data Elements WG meeting and viewed to the 7/2 recording. In the meetings, presenters discussed several query parameter logic, data and profile models—including QUICK & QIDAM, CQL, FHIR, QED, QDM, vMR and QBPv3—and efforts to map these models to CDA/C-CDA and to each other (more or less). Much work has been going into development of these standards and considerably more is needed. There are few implementations acutally using them, partly due to technical complexities and non-technical (business layer) issues. Definitions With this in mind, let’s consider the differing needs of the two primary use cases for implementing data element queries via DAF Direct: 1. “Basic” use case includes situations in which: (a) a Responder’s EHR system cannot effectively handle CDA OIDs or codes, parse XML, and/or utilize value sets stored only on the Web; (b) a Responder does not want to rely on Web services for transport; or (c) a Responder does not have an EHR, but can do patient chart reviews to supply the requested data. The Direct transport protocol for this use case would typically be the “Simple SMTP” model (as per the Applicability Statement for Secure Health Transport). 2. “Complex” use case includes situations in which EHR system performs automated queries. The Direct transport protocol for this use case would typically be the “SMTP with Full Service HISPs” model (as per the Applicability Statement) and rely on SOAP or RESTful web-service transport protocols. Rationale The Basic use case would benefit many long term healthcare facilities, providers using CDA readers, EHR systems that lack required querying capabilities, and Responders who prefer not to implement automated web-service queries. Since the main DAF WG has not focused on the Basic use case, I now propose a model that defines query parameters for the Basic use case. This Basic parameter definition model would: Store the query parameters in a human readable file and in a standardized layout/structure using a simple expression language Map the query parameters to HL7 CDA clinical concepts using standardized vocabularies and value sets. In addition, it was proposed that the human readable file for Basic queries also be included in the payload sent to responders of Complex queries to provide a description what is to be done (even when a query is automated). This would avoid the issue of the query Requestor having to determine the Responder’s query capabilities. Issue of Scope During the 8/4/2014 SWG meeting, a question of arose about whether this Basic use case was in scope since it was not addressed in the DAF Charter. I said this was an oversight that only became apparent in this SWG when we examined the value of the Basic use case’s Simple SMTP transport in its ability to deliver any type of payload and format in a zipped e-mail attachment without requisite SOAP headers, XDM packaging, XML and HL7 formats, etc. Page 1 of 34 In an early meeting of the SWG, I mentioned a post to the wiki from Walter Sujansky in which his report -http://www.projecthealthdesign.org/media/file/Standard-Model-For-Collecting-And-ReportingPGHI_Sujansky_Assoc_2013-07-18.pdf -- included a description of a parameter definition model for unstructured request/response messages over DIRECT, which he called the Basic Document Retrieval model. Group members indicated that this unstructured data model is unacceptable for DAF since “unstructured” is not an interoperable standard. This meant that structured model would be required even for very basic documentbased queries and, therefore, a structured parameter definition model for basic data element queries is alos required. In response, I designed a possible structure query definition model for the Basic use case, which I'm calling the Query Parameters Definition Grid. A related question was discussed about whether FHIR, which appears to be the likely standard to be selected by the main DAF WG, would be a suitable structure for the Basic use case. Reasons why it would not be suitable include the need to parse its XML or JASON data representations in FHIR and the uncertainty that FHIR’s dependence on REST can be broken in order to deliver a FHIR-based payload via Simple SMTP. The meeting concluded with members asking me to present my Basic model to the large DAF WG on 8/6, which I will do so. Query Parameters Definition Grid Components I propose for that the query parameters for the Basic use case be stored in files that: 1. Represent the parameters in simple human readable format structured in a query parameters definition grid (rather in using XML or HL7v2), as depicted in the Appendix, which uses a straight-forward expression language. 2. Mirror the Complex use case for patient identifiers and demographics, as well as information related to patient privacy, although representing them in the query parameters definition grid. 3. Include all relevant value sets as locally searchable lists (rather than requiring remote Web access). 4. Base the query parameters for clinical data elements and attributes on the C-CDA, which include the following clinical catagories and subcategories a. Advance directives i. Directive Type ii. Effective as of iii. Expires on iv. Patient's Directive v. Document of Record b. Allergies, adverse reactions, alerts i. Vaccine ii. Date iii. Status c. Family history i. Relationship ii. Diagnosis iii. Age at onset Page 2 of 34 d. Functional status i. Functional or Cognitive Finding ii. Observation iii. Observation Date iv. Condition Status e. Immunizations i. Vaccine ii. Date iii. Status f. Medications i. Intended Use ii. Type iii. Brand Name iv. Generic Name v. Drug Vehicle vi. Medication Route vii. Status viii. Start Date ix. End Date x. Instructions xi. Where to Administer xii. Administrative Unit xiii. Repeat Number xiv. Precondition xv. Frequency xvi. Dose Quantity xvii. Rate Quantity xviii. Max Dose xix. Indication g. Medical equipment i. Supply/Device ii. Date supplied h. Payers i. Policy type / Coverage type ii. Covered party ID iii. Policy Holder i. Plan of care i. Planned activity ii. Planned date j. Problems i. Condition ii. Effective Dates iii. Status Page 3 of 34 k. Procedures i. Procedure ii. Date l. Results i. Laboratory test ii. Test result value iii. Reference range m. Social history i. Social history element ii. Description iii. Effective dates n. Vital signs i. Height ii. Weight iii. Blood Pressure iv. etc. 5. Indicate Time variables as needed a. Start date b. End date c. Effective time d. Birth date e. Years, months, days, hours, minutes, seconds 6. Indicate Status variables as needed a. Aborted b. Active c. Cancelled d. Completed e. Held f. Suspended 7. Indicate Quantity/Level/Degree variables as needed, e.g.: a. Units of measure (other than time) i. Measurement system 1. Imperial and US Customary system 2. Metric system ii. Measurement type, including: 1. Length 2. Weight 3. Distance 4. Location 5. Volume 6. Frequency (number of occurances per time period) 7. Intensity (e.g., Mild/Moderate/Severe, Low/Medium/High) 8. Duration (time period during which something exists/occures) Page 4 of 34 9. Count (number of units) 8. Indicate Mathematical and Logical Operators (e.g., <, >, ≤, ≥, ≠, =, and, or, not, else, any, none, contains, does not contain, before, after) as needed Page 5 of 34 Appendix: Example of Query Parameters Definition Grid and Value Sets Structure Here’s an example of the proposed query parameters defintion grid and value sets structure for storing query parameters in the Basic use case based on the rather complex NQF 0059 population health quality metric. It requests a count of the number of patients in a defined popluation of diabetic patients (the denominator) and the number of those patients with an HbA1c level >9.0% (the numerator). Note 1: The values sets referenced in the Data Criteria/Value column are located beneath the query parameters definition grid in the Diabetes-Related Value Sets section. Note 2: If the query was for a single patient: (a) the Initial Patient Population Criteria section would be replace with a Patient Identification section containing a patient’s identification information and (b) the Numerator and Denominator sections would be replaced by a “Clinical Data Requested” section. I will provide an example of this in the next version of this document. Note 3: The structure of a Privacy Protection section is TBD. Query Parameters Definition Grid Description of Parameter Data Category/Type Data Criteria/Value Measurement End Date Measurement Period Measurement End Date 2014-Aug-01 Initial Patient Population Criteria Patient Age in years at the Measurement End date is between 18 and75 Patient Age End Date - Birth Date >=18 years AND: End Date - Birth Date <=75 years Denominator Criteria All patients in the Initial Patient Population AND: Medications criterion: Medications indicative of diabetes that are ordered, dispensed or active <=2 years before or simultaneously to the measurement end date Name or ID State Effective Time In Diabetes Medications Value Set =Ordered OR: =Dispensed OR: =Active <=Measurement End Date – 2 Years |OR: (If the medication criterion is not met) Problem/Condition/Diagnosis criterion: Active diabetes diagnosis <=2 years before or simultaneously to the measurement end date Exception: Active diagnosis of polycystic ovaries, gestational diabetes, or steroid induced diabetes Status In Diabetes Diagnosis Codes & Names Value Set =Active Effective Time <=Measurement End Date – 2 Years Problem-Condition Problem-Condition Status Page 6 of 34 =polycystic ovaries OR: =gestational diabetes OR: =steroid induced diabetes =Active ||AND: (If the medications criterion in not met, but the Problem/Condition/Diagnosis criterion is met, then one of two Encounter criteria must also be met) Encounter criterion: 1 or more Type In Acute Encounter Name Value Set acute inpatient or ED encounters Effective Time <=Measurement End Date – 2 Years <=2 years before or simultaneously to measurement Frequency >=1 Encounter end date |||OR: { If the acute inpatient encounter criterion is not met, then the following must be met) 2 or more encounters in non‐ Type In Non-Acute Encounter Name Value Set acute inpatient, outpatient, or Effective Time <=Measurement End Date – 2 Years ophthalmology occurring on Frequency >=2 Encounters different dates Numerator Criteria Patients is in the Initial Patient Population AND: Laboratory test result HbA1c test using HbA1c test code list grouping during the measurement period Patients whose last HbA1c text >9.0% Lab Test Type Effective Time In Diabetes Lab Test Value Set Most recent HbA1c Lab Test Result Value >9.0% mg/dl Diabetes-Related Value Sets Diabetes Diagnosis Codes & Names Diabetes Diagnosis Codes ICD-9-CM Diabetes Diagnosis Codes >= 249 <=250.93 251.8 648.83 775.1 790.29 ICD-10-CM Diabetes Diagnosis Codes E13.31 O24.42 R73.02 R73.09 E13.43 E13.33 E13.32 E13.35 E13.34 T38 Page 7 of 34 E28.2 E08 E10 E10.36 E11.36 SNOMED-CT Diabetes Diagnosis Codes 111552007 111558006 11530004 11687002 123763000 127013003 127014009 190321005 190328004 190330002 190331003 190336008 190353001 190361006 190368000 190369008 190371008 190372001 190383005 190389009 190390000 190392008 190406000 190407009 190410002 190411003 190412005 190416001 190416008 190417004 190418009 190419001 190422004 190447002 193184006 197605007 198609003 199223000 199227004 199229001 Page 8 of 34 199230006 199231005 199234002 201250006 201251005 201252003 23045005 230572002 230577008 237599002 237600004 237601000 237604008 237613005 237618001 237619009 237627000 25907005 26298008 267379000 267380002 2751001 275918005 28032008 28453007 290002008 309426007 310387003 311366001 312912001 313435000 313436004 314537004 314771006 314772004 314893005 314902007 314903002 33559001 34140002 359611005 359638003 359642000 360546002 371087003 38542009 Page 9 of 34 39058009 39181008 408539000 408540003 413183008 414890007 414906009 420414003 420422005 420491007 420738003 420989005 421223006 421389009 421443003 421750000 421847006 421895002 422155003 422183001 422228004 422275004 423263001 424736006 424989000 425159004 425442003 426705001 426875007 427089005 428896009 42954008 44054006 4627003 46635009 46894009 50620007 51002006 53126001 5368009 54181000 57886004 59079001 5969009 69878008 70694009 Page 10 of 34 71546005 73211009 74263009 75022004 75524006 75682002 76751001 81531005 81830002 8801005 91352004 9859006 Diabetes Diagnosis Names Abnormal glucose tolerance Abnormal maternal glucose tolerance, antepartum Abnormal maternal glucose tolerance, complicating pregnancy, childbirth, or the puerperium, unspecified as to episode of care Abnormal maternal glucose tolerance, previous postpartum condition Abnormal maternal glucose tolerance, with delivery Abnormal maternal glucose tolerance, with delivery, with current postpartum complication Adrenal cortical steroids Adult-onset diabetes Adult-onset diabetes mellitus Background diabetic retinopathy Brittle diabetes Bronze diabetes Bronzed diabetes Carpenter syndrome Central diabetes insipidus Chronic painful diabetic neuropathy complications of pregnancy, childbirth and the puerperium Corticosteroid-induced diabetes DI Diabetes Diabetes insipidus Diabetes mellitus diabetes mellitus AND insipidus with optic atrophy AND deafness diabetes mellitus associated with cystic fibrosis diabetes mellitus associated with genetic syndrome diabetes mellitus associated with hormonal etiology diabetes mellitus associated with pancreatic disease diabetes mellitus associated with receptor abnormality diabetes mellitus autosomal dominant type II diabetes mellitus due to cystic fibrosis diabetes mellitus due to insulin receptor antibodies diabetes mellitus due to structurally abnormal insulin Page 11 of 34 diabetes mellitus during pregnancy - baby not yet delivered diabetes mellitus during pregnancy, childbirth and the puerperium Diabetes mellitus during pregnancy, childbirth or the puerperium NOS Diabetes mellitus in mother complicatin pregnancy, childbirth AND/OR puerperium diabetes mellitus induced by non-steroid drugs diabetes mellitus induced by non-steroid drugs without complication Diabetes mellitus NOS with ketoacidosis Diabetes mellitus NOS with neurological manifestation Diabetes mellitus NOS with peripheral circulatory disorder Diabetes mellitus NOS with unspecified complication Diabetes mellitus of mother with delivery Diabetes mellitus type 1 Diabetes mellitus type 2 diabetes mellitus type 2 in nonobese diabetes mellitus type 2 in obese Diabetes mellitus type I Diabetes mellitus type II diabetes mellitus with no mention of complication diabetes mellitus with other specified manifestation diabetes mellitus without complication Diabetes mellitus without mention of complication Diabetes mellitus without mention of complication, type I [juvenile type], not stated as uncontrolled Diabetes mellitus without mention of complication, type I [juvenile type], uncontrolled Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled Diabetes mellitus without mention of complication, type II or unspecified type, uncontrolled diabetes mellitus, adult onset, with hyperosmolar coma diabetes mellitus, adult onset, with no mention of complication diabetes mellitus, adult onset, with other specified manifestation diabetes mellitus, juvenile type, with hyperosmolar coma diabetes mellitus, juvenile type, with no mention of complication diabetes mellitus, juvenile type, with other specified manifestation Diabetes with hyperosmolarity, type I [juvenile type], not stated as uncontrolled Diabetes with hyperosmolarity, type I [juvenile type], uncontrolled Diabetes with hyperosmolarity, type II or unspecified type, not stated as uncontrolled Diabetes with hyperosmolarity, type II or unspecified type, uncontrolled Diabetes with ketoacidosis, type I [juvenile type], not stated as uncontrolled Diabetes with ketoacidosis, type I [juvenile type], uncontrolled Diabetes with ketoacidosis, type II or unspecified type, not stated as uncontrolled Diabetes with ketoacidosis, type II or unspecified type, uncontrolled Diabetes with neurological manifestations, type I [juvenile type], not stated as uncontrolled Diabetes with neurological manifestations, type I [juvenile type], uncontrolled Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled Diabetes with neurological manifestations, type II or unspecified type, uncontrolled Diabetes with ophthalmic manifestations, type I [juvenile type], not stated as uncontrolled Diabetes with ophthalmic manifestations, type I [juvenile type], uncontrolled Diabetes with ophthalmic manifestations, type II or unspecified type, not stated as uncontrolled Page 12 of 34 Diabetes with ophthalmic manifestations, type II or unspecified type, uncontrolled Diabetes with other coma, type I [juvenile type], not stated as uncontrolled Diabetes with other coma, type I [juvenile type], uncontrolled Diabetes with other coma, type II or unspecified type, not stated as uncontrolled Diabetes with other coma, type II or unspecified type, uncontrolled Diabetes with other specified manifestations Diabetes with other specified manifestations, type I [juvenile type], not stated as uncontrolled Diabetes with other specified manifestations, type I [juvenile type], uncontrolled Diabetes with other specified manifestations, type II or unspecified type, not stated as uncontrolled Diabetes with other specified manifestations, type II or unspecified type, uncontrolled Diabetes with peripheral circulatory disorders Diabetes with peripheral circulatory disorders, type I [juvenile type], not stated as uncontrolled Diabetes with peripheral circulatory disorders, type I [juvenile type], uncontrolled Diabetes with peripheral circulatory disorders, type II or unspecified type, not stated as uncontrolled Diabetes with peripheral circulatory disorders, type II or unspecified type, uncontrolled Diabetes with renal manifestations, type I [juvenile type], not stated as uncontrolled Diabetes with renal manifestations, type I [juvenile type], uncontrolled Diabetes with renal manifestations, type II or unspecified type, uncontrolled Diabetes with unspecified complication Diabetes with unspecified complication, type I [juvenile type], not stated as uncontrolled Diabetes with unspecified complication, type I [juvenile type], uncontrolled Diabetes with unspecified complication, type II or unspecified type, not stated as uncontrolled Diabetes with unspecified complication, type II or unspecified type, uncontrolled diabetes-deafness syndrome maternally transmitted Diabetes-nephrosis syndrome Diabetic amyotrophy Diabetic autonomic neuropathy Diabetic autonomic neuropathy associated with type 1 diabetes mellitus Diabetic autonomic neuropathy associated with type 2 diabetes mellitus Diabetic coma with ketoacidosis Diabetic complication Diabetic foot ulcer Diabetic gangrene Diabetic gastroparesis Diabetic gastroparesis associated with type 1 diabetes mellitus Diabetic gastroparesis associated with type 2 diabetes mellitus Diabetic glomerulopathy Diabetic intracapillary glomerulosclerosis Diabetic ketoacidosis Diabetic macular edema Diabetic mononeuropathy Diabetic mononeuropathy simplex Diabetic neuropathy Diabetic neuropathy with neurologic complication Diabetic optic papillopathy Diabetic peripheral angiopathy Page 13 of 34 Diabetic peripheral neuropathy Diabetic radiculopathy Diabetic renal disease Diabetic retinopathy Diabetic skin ulcer DM drug-induced diabetes mellitus Evidence of treatment for nephropathy fibrocalculous pancreatic diabetes Gangrene associated with diabetes mellitus GDM Gestational diabetes Gestational diabetes mellitus gestational diabetes mellitus, class A>1< gestational diabetes mellitus, class A>2< gestational diabetes mellitus, class B gestational diabetes mellitus, class B>1< gestational diabetes mellitus, class C gestational diabetes mellitus, class D gestational diabetes mellitus, class F gestational diabetes mellitus, class H gestational diabetes mellitus, class R gestational diabetes mellitus, class T Growth-onset diabetes mellitus Hemochromatosis Houssay's syndrome Hyperosmolality due to uncontrolled type I diabetes mellitus hyperproinsulinemia Hypoglycemic shock IDD IDDM Immune-mediated Impaired glucose tolerance insulin autoimmune syndrome Insulin coma insulin dependent diabetes mellitus type IA insulin dependent diabetes mellitus type IB Insulin-dependent insulin-dependent diabetes mellitus secretory diarrhea syndrome insulin-resistant diabetes mellitus AND acanthosis nigricans insulin-treated non-insulin-dependent diabetes mellitus Ischemic ulcer diabetic foot Juvenile diabetes mellitus Juvenile-onset diabetes Juvenile-onset diabetes mellitus Ketoacidosis in type II diabetes mellitus Page 14 of 34 Ketoacidotic coma in type II diabetes mellitus Ketosis-prone diabetes mellitus Kimmelstiel-Wilson syndrome LADA latent autoimmune diabetes mellitus in adult Latent autoimmune diabetes of adults malnutrition related diabetes mellitus malnutrition-related diabetes mellitus - fibrocalculous malnutrition-related diabetes mellitus with ketoacidosis malnutrition-related diabetes mellitus with multiple complications malnutrition-related diabetes mellitus with peripheral circulatory complications malnutrition-related diabetes mellitus with renal complications malnutrition-related diabetes mellitus without complications Maternal diabetes mellitus with delivery, with current postpartum complication Maternal diabetes mellitus, antepartum Maternal diabetes mellitus, complicating pregnancy, childbirth, or the puerperium, unspecified as to episode of care Maternal diabetes mellitus, previous postpartum condition maturity onset diabetes mellitus in young Maturity-onset Mild nonproliferative diabetic retinopathy Mixed diabetic ulcer - foot Moderate nonproliferative diabetic retinopathy multiple complications of type I diabetes mellitus multiple complications of type II diabetes mellitus Neonatal Diabetes Neonatal Diabetes Mellitus Nephrogenic diabetes insipidus Nephrotic syndrome in diabetes mellitus Neuropathic diabetic ulcer - foot NIDDM NIDDM in nonobese Nodular glomerulosclerosis Nonclinical diabetes Non-insulin dependent diabetes Non–insulin-dependent diabetes mellitus Nonproliferative diabetic retinopathy NOS O/E - left chronic diabetic foot ulcer O/E -right chronic diabetic foot ulcer Other specified diabetes mellitus with coma Other specified diabetes mellitus with diabetic autonomic (poly)neuropathy Other specified diabetes mellitus with moderate nonproliferative diabetic retinopathy Other specified diabetes mellitus with nonproliferative diabetic retinopathy NOS Other specified diabetes mellitus with proliferative diabetic retinopathy Other specified diabetes mellitus with severe nonproliferative diabetic retinopathy Peripheral circulatory disorder associated with diabetes mellitus Page 15 of 34 pineal hyperplasia AND diabetes mellitus syndrome Poisoning by adrenal cortical steroid Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified Polycystic ovaries Preclinical diabetes Pre-diabetes pre-existing diabetes mellitus, insulin-dependent pre-existing diabetes mellitus, non-insulin-dependent Pre-existing malnutrition-related diabetes mellitus pregnancy and non-insulin-dependent diabetes mellitus Proliferative diabetic retinopathy protein-deficient diabetes mellitus Renal diabetes secondary diabetes mellitus secondary endocrine diabetes mellitus Severe nonproliferative diabetic retinopathy Steroid induced diabetes steroid-induced diabetes mellitus without complication Subclinical diabetes Type 1 d. Mellitus Type 1 diabetes Type 1 diabetes mellitus Type 1 diabetes mellitus with diabetic cataract Type 2 d. mellitus Type 2 diabetes Type 2 diabetes mellitus Type 2 diabetes mellitus with diabetic cataract Type 2 diabetes mellitus without complications Type I diabetes Type I diabetes mellitus Type I diabetes mellitus - poor control Type I diabetes mellitus maturity onset Type I diabetes mellitus with arthropathy Type I diabetes mellitus with gangrene Type I diabetes mellitus with hypoglycemic coma Type I diabetes mellitus with ulcer Type I diabetes mellitus without complication Type II diabetes Type II diabetes mellitus Type II diabetes mellitus - poor control Type II diabetes mellitus with arthropathy Type II diabetes mellitus with gangrene Type II diabetes mellitus with hypoglycemic coma Type II diabetes mellitus with peripheral angiopathy Type II diabetes mellitus with ulcer Page 16 of 34 Type II diabetes mellitus without complication unspecified diabetes mellitus with multiple complications unstable diabetes unstable type I diabetes mellitus Diabetes Medication Codes & Names Diabetes Medication Codes RxNorm Codes 105374 105374 153842 197306 197307 197495 197496 197737 198291 198292 198293 198294 199149 199150 199245 199246 199247 199825 199984 199985 200065 200132 200256 200257 200258 205314 205329 205330 205331 237527 242120 242916 242917 252960 259111 260265 283394 310488 310489 Page 17 of 34 310490 310534 310536 310537 310539 311040 311041 311053 311054 311055 311056 311057 311058 311059 311060 311061 311919 312440 312441 312859 312860 312861 313418 313419 314000 314006 314038 314142 315107 315239 317573 317800 351297 358349 379804 389137 389139 401938 484322 485210 544614 602544 602549 602550 647237 647239 Page 18 of 34 665033 665038 665042 706895 706896 744863 757710 757712 763002 763007 763013 763014 833159 844809 844824 844827 847191 847207 847211 847230 847239 847252 847259 847263 847416 847910 847915 860975 860978 860981 860984 860996 860999 861004 861007 861010 861021 861025 861035 861039 861042 861044 861731 861736 861740 861743 Page 19 of 34 861748 861753 861760 861763 861769 861783 861787 861790 861795 861806 861816 861819 861822 NDC Codes 00002751001 00002751101 00002751201 00002751601 00002821501 00002831501 00002850101 00002871501 2872501 2873001 2877001 2879301 2879401 2879701 2879901 2951501 3421411 6011201 6057561 7314813 7316318 9007002 9013101 9034101 9501201 26286148 26286151 26286251 26286351 29315818 39005110 39022110 Page 20 of 34 49155066 49411066 54014025 54014120 54014125 54014225 69005019 69005053 69005085 69070737 69393066 78035105 87607211 87607731 88221905 88222033 88222052 88250033 88250052 88250205 115115001 115115002 115115101 115115102 115115201 115115202 169001771 169004571 169008181 169009201 169183311 169183317 169183417 169183711 169231321 169231421 169231721 169330312 169368213 169368512 169368712 169369619 169406012 169633910 169643910 169750111 Page 21 of 34 172224580 247192430 247192530 247192630 555044202 555044302 12280006030 13411010103 13411010203 13411010303 16252052301 16252052401 16252052501 21695014715 21695014815 35356013060 49999045030 49999045130 50419086148 50419086151 50419086251 50419086351 51641040501 54569450100 54569606100 54868382301 54868538200 54868538400 54868550000 54868550001 54868555300 54868555301 54868583100 54868583101 54868594500 55289017142 59060183302 59060183402 59060183702 59060231704 64764015518 64764015560 64764015818 64764015860 64764030230 64764031030 Page 22 of 34 64764051030 66780011502 66780012102 Diabetes Medication Names Diabetes Medication Brand Names Acarbose 60 ACTUAT exenatide 0.01 MG/ACTUAT Prefilled Syringe Acarbose 100 MG Oral Tablet Acarbose 25 MG Oral Tablet Acarbose 50 MG Oral Tablet Acarbose Acetohexamide Actoplus met 15 MG Oral Tablet Actoplus met XR 15 MG Oral Tablet Actoplus Met XR Actoplus Met Actos 15 MG Oral Tablet Actos Amaryl Apidra OptiClik Cartridge Apidra SoloStar Pen Apidra Avandamet Avandaryl Avandia Byetta Prefilled Pen Chlorpropamide DiaBeta Diabinese Duetact Exenatide Exubera Combination Pack 12 Exubera Combination Pack 15 Exubera Kit Exubera Gliclazide 30 MG Extended Release Tablet Gliclazide 80 MG Oral Tablet Gliclazide glimepiride glipizide ER glipizide glipizide/metformin hydrochloride Glucotrol XL Glucotrol Glucovance glyburide Page 23 of 34 Glynase PresTab Glyset Humalog Cartridge Humalog KwikPen Humalog Mix 50/50 Pen Humalog Mix 50/50 Humalog Mix 75/25 KwikPen Humalog Mix 75/25 Pen Humalog Mix 75/25 Humalog Pen Humalog Humulin 50/50 Humulin 70/30 Pen Humulin 70/30 Humulin N Pen Humulin N Humulin R (Concentrated) Humulin R insulin Glargine insulin Lispro insulin insulin, Aspart Protamine, Human insulin, Aspart, Human insulin, Glulisine, Human insulin, Prompt Zinc, Beef insulin, Prompt Zinc, Beef-Pork insulin, Prompt Zinc, Pork insulin, Protamine Zinc, Beef-Pork insulin, Protamine Zinc, Pork insulin, Regular, Beef insulin, Regular, Beef-Pork insulin, Regular, Pork insulin, Zinc, Human insulin, Zinc, Pork Janumet Januvia Lantus OptiClik Cartridge Lantus Solostar Pen Lantus Levemir FlexPen Levemir Metaglip metformin hydrochloride metformin Micronase Miglitol Page 24 of 34 Miglustat 100 MG Oral Capsule Miglustat Nateglinide Novolin 70/30 Innolet Novolin 70/30 PenFill Novolin 70/30 Novolin N Innolet Novolin N PenFill Novolin N Novolin R Innolet Novolin R PenFill Novolin R NovoLog FlexPen NovoLog Mix 70/30 FlexPen Novolog Mix 70/30 PenFill NovoLog Mix 70/30 NovoLog PenFill NovoLog Onglyza Pioglitazone PrandiMet Prandin Precose Relion Novolin 70/30 Innolet Relion Novolin N ReliOn/Novolin 70/30 ReliOn/Novolin R Repaglinide Rosiglitazone Sitagliptin Phosphate Starlix Symlin SymlinPen 120 SymlinPen 60 tolazamide Tolbutamide 250 MG Oral Tablet Tolbutamide 50 MG/ML Injectable Solution Tolbutamide 500 MG Oral Tablet Tolbutamide Tolbutamide Tolinase Tol-Tab Victoza Diabetes Medication Generic Names acarbose acetohexamide 250 MG Oral Tablet Page 25 of 34 acetohexamide 250 mg oral tablet acetohexamide 500 MG Oral Tablet acetohexamide 500 mg oral tablet acetohexamide acetohexamide aspart human insulin 300 UNT per 3 ML Prefilled Syringe aspart protamine human insulin 210 UNT / aspart human insulin 90 UNT per 3 ML Prefilled Syringe chlorpropamide 100 MG Oral Tablet chlorpropamide 250 MG Oral Tablet chlorpropamide detemir insulin 300 UNT per 3 ML Prefilled Syringe exenatide 0.25 MG/ML Injectable Solution exenatide 10 mcg/0.04 mL subcutaneous solution exenatide 5 mcg/0.02 mL subcutaneous solution exenatide 5 MCG/ACTUAT Prefilled Syringe, 60 ACTUAT exenatide glargine insulin 300 UNT per 3 ML Prefilled Syringe glimepiride 1 MG / rosiglitazone 4 MG Oral Tablet glimepiride 1 MG Oral Tablet glimepiride 2 MG / pioglitazone 30 MG Oral Tablet glimepiride 2 MG / rosiglitazone 4 MG Oral Tablet glimepiride 2 MG / rosiglitazone 8 MG Oral Tablet glimepiride 2 MG Oral Tablet glimepiride 3 MG Oral Tablet glimepiride 4 MG / pioglitazone 30 MG Oral Tablet glimepiride 4 MG / rosiglitazone 4 MG Oral Tablet glimepiride 4 MG / rosiglitazone 8 MG Oral Tablet glimepiride 4 MG Oral Tablet glimepiride glimepiride-pioglitazone 2 mg-30 mg oral tablet glimepiride-pioglitazone 4 mg-30 mg oral tablet glimepiride-rosiglitazone 1 mg-4 mg oral tablet glimepiride-rosiglitazone 2 mg-4 mg oral tablet glimepiride-rosiglitazone 2 mg-8 mg oral tablet glimepiride-rosiglitazone 4 mg-4 mg oral tablet glimepiride-rosiglitazone 4 mg-8 mg oral tablet glipizide 10 MG Extended Release Tablet glipizide 10 MG Oral Tablet glipizide 10 mg oral tablet, extended release glipizide 2.5 MG / metformin hydrochloride 250 MG Oral Tablet glipizide 2.5 MG / metformin hydrochloride 500 MG Oral Tablet glipizide 2.5 MG Extended Release Tablet glipizide 2.5 MG Oral Tablet glipizide 2.5 mg oral tablet, extended release glipizide 5 MG / metformin hydrochloride 500 MG Oral Tablet glipizide 5 MG Extended Release Tablet Page 26 of 34 glipizide 5 MG Oral Tablet glipizide 5 mg oral tablet, extended release glipizide ER 10 MG 24 HR Extended Release Tablet glipizide ER 2.5 MG 24 HR Extended Release Tablet glipizide ER 5 MG 24 HR Extended Release Tablet glipizide extended release glipizide XL glipizide glipizide-metformin 2.5 mg-250 mg oral tablet glipizide-metformin 2.5 mg-500 mg oral tablet glipizide-metformin 5 mg-500 mg oral tablet glipizide-metformin gliquidone 30 MG Oral Tablet glyburide 1.25 MG / metformin hydrochloride 250 MG Oral Tablet glyburide 1.25 MG Oral Tablet glyburide 1.5 MG Oral Tablet glyburide 2.5 MG / metformin hydrochloride 500 MG Oral Tablet glyburide 2.5 MG Oral Tablet glyburide 3 MG Oral Tablet glyburide 4.5 MG Oral Tablet glyburide 5 MG / metformin hydrochloride 500 MG Oral Tablet glyburide 5 MG Oral Tablet glyburide 6 MG Oral Tablet glyburide micronized 1.5 mg oral tablet glyburide micronized 3 mg oral tablet glyburide micronized 6 mg oral tablet glyburide glyburide, micronized glyburide-metformin 1.25 mg-250 mg oral tablet glyburide-metformin 2.5 mg-500 mg oral tablet glyburide-metformin 5 mg-500 mg oral tablet glyburide-metformin insulin aspart 100 units/mL subcutaneous solution insulin aspart-insulin aspart protamine 30 units-70 units/mL subcutaneous suspension insulin biphasic aspart 50/50 100 UNT/ML Injectable Suspension insulin detemir 100 units/mL subcutaneous solution insulin detemir 100 UNT/ML Injectable Solution insulin glargine 100 units/mL subcutaneous solution insulin glargine 100 UNT/ML Injectable Solution insulin glulisine 100 units/mL subcutaneous solution insulin human, rDNA origin 1 MG/ACTUAT Inhalant Powder insulin human, rDNA origin 3 MG/ACTUAT Inhalant Powder insulin inhalation, rapid acting 1 mg and 3 mg inhalation powder insulin inhalation, rapid acting 1 mg inhalation powder insulin inhalation, rapid acting 3 mg inhalation powder insulin isophane human recombinant 100 units/mL subcutaneous suspension Page 27 of 34 insulin isophane-insulin regular human recombinant 50 units-50 units/mL subcutaneous suspension insulin lispro 100 units/mL subcutaneous solution insulin Lispro 25 UNT/ML / insulin, Protamine Lispro, Human 75 UNT/ML Injectable Suspension insulin Lispro 50 UNT/ML / insulin, Protamine Lispro, Human 50 UNT/ML Injectable Suspension insulin lispro-insulin lispro protamine 25 units-75 units/mL subcutaneous suspension insulin lispro-insulin lispro protamine 50 units-50 units/mL subcutaneous suspension insulin regular human recombinant (concentrated) 500 units/mL subcutaneous solution insulin regular human recombinant 100 units/mL injectable solution insulin, Aspart Protamine, Human 70 UNT/ML / insulin, Aspart, Human 30 UNT/ML Injectable Suspension insulin, Aspart, Human 100 UNT/ML Injectable Solution insulin, Glulisine, Human 100 UNT/ML 3 ML Prefilled Syringe insulin, Glulisine, Human 100 UNT/ML Injectable Solution insulin, Prompt Zinc, Beef 100 UNT/ML Injectable Suspension insulin, Prompt Zinc, Beef-Pork 100 UNT/ML Injectable Suspension insulin, Prompt Zinc, Beef-Pork 40 UNT/ML Injectable Suspension insulin, Prompt Zinc, Pork 100 UNT/ML Injectable Suspension insulin, protamine zinc, beef 100 UNT/ML Injectable Suspension insulin, Protamine Zinc, Beef-Pork 100 UNT/ML Injectable Suspension insulin, Protamine Zinc, Beef-Pork 40 UNT/ML Injectable Suspension insulin, Protamine Zinc, Pork 100 UNT/ML Injectable Suspension insulin, Regular, Beef 100 UNT/ML Injectable Solution insulin, Regular, Beef-Pork 100 UNT/ML Injectable Solution insulin, Regular, Beef-Pork 40 UNT/ML Inhalant Solution insulin, Regular, Pork 100 UNT/ML Injectable Solution insulin, Regular, Pork 30 UNT/ML / NPH insulin, Pork 70 UNT/ML Injectable Suspension insulin, Regular, Pork 40 UNT/ML Injectable Solution insulin, Regular, Pork 500 UNT/ML Injectable Solution insulin, Zinc, Human 100 UNT/ML Injectable Suspension insulin, Zinc, Pork 100 UNT/ML Injectable Suspension insulin, Zinc, Pork 40 UNT/ML Injectable Solution liraglutide 18 mg/3 mL subcutaneous injection lispro insulin 150 UNT / protamine lispro human insulin 150 UNT per 3 ML Prefilled Syringe lispro insulin 150 UNT per 1.5 ML Prefilled Syringe lispro insulin 300 UNT per 3 ML Prefilled Syringe lispro insulin 75 UNT / protamine lispro human insulin 225 UNT per 3 ML Prefilled Syringe lispro PRC metformin hydrochloride 100 MG/ML Oral Solution metformin hydrochloride 1000 MG / rosiglitazone 2 MG Oral Tablet metformin hydrochloride 1000 MG / rosiglitazone 4 MG Oral Tablet metformin hydrochloride 1000 MG / sitagliptin 50 MG Oral Tablet metformin hydrochloride 1000 MG 24 HR Extended Release Tablet metformin hydrochloride 1000 MG Extended Release Tablet metformin hydrochloride 1000 MG Oral Tablet metformin hydrochloride 24 HR 500 MG Extended Release Tablet metformin hydrochloride 500 MG / pioglitazone 15 MG Oral Tablet metformin hydrochloride 500 MG / repaglinide 1 MG Oral Tablet Page 28 of 34 metformin hydrochloride 500 MG / repaglinide 2 MG Oral Tablet metformin hydrochloride 500 MG / rosiglitazone 1 MG Oral Tablet metformin hydrochloride 500 MG / rosiglitazone 2 MG Oral Tablet metformin hydrochloride 500 MG / rosiglitazone 4 MG Oral Tablet metformin hydrochloride 500 MG / sitagliptin 50 MG Oral Tablet metformin hydrochloride 500 MG Extended Release Tablet metformin hydrochloride 500 MG Oral Tablet metformin hydrochloride 625 MG Oral Tablet metformin hydrochloride 750 MG 24 HR Extended Release Tablet metformin hydrochloride 750 MG Extended Release Tablet metformin hydrochloride 850 MG / pioglitazone 15 MG Oral Tablet metformin hydrochloride 850 MG Oral Tablet metformin metformin-pioglitazone 1000 mg-15 mg oral tablet, extended release metformin-pioglitazone 1000 mg-30 mg oral tablet, extended release metformin-pioglitazone 500 mg-15 mg oral tablet metformin-pioglitazone 850 mg-15 mg oral tablet metformin-repaglinide 500 mg-1 mg oral tablet metformin-rosiglitazone 1000 mg-2 mg oral tablet metformin-rosiglitazone 1000 mg-4 mg oral tablet metformin-rosiglitazone 500 mg-1 mg oral tablet metformin-rosiglitazone 500 mg-2 mg oral tablet metformin-rosiglitazone 500 mg-4 mg oral tablet metformin-sitagliptin 1000 mg-50 mg oral tablet metformin-sitagliptin 500 mg-50 mg oral tablet miglitol 100 MG Oral Tablet miglitol 25 MG Oral Tablet miglitol 50 MG Oral Tablet miglitol nateglinide 120 MG Oral Tablet nateglinide 180 MG Oral Tablet nateglinide pioglitazone 15 MG Oral Tablet pioglitazone 30 MG Oral Tablet pioglitazone 45 MG Oral Tablet pioglitazone pramlintide 1000 mcg/mL subcutaneous solution pramlintide 600 mcg/mL subcutaneous solution pramlintide acetate 0.6 MG/ML Injectable Solution pramlintide acetate 1 MG/ML Injectable Solution pramlintide acetate 1.5 MG per 1.5 ML Prefilled Syringe pramlintide acetate 2.7 MG per 2.7 ML Prefilled Syringe rDNA origin human insulin 1 MG/ACTUAT Dry Powder Inhaler, 90 ACTUAT rDNA origin human insulin 3 MG/ACTUAT Dry Powder Inhaler, 90 ACTUAT repaglinide 0.5 MG Oral Tablet repaglinide 1 MG Oral Tablet Page 29 of 34 repaglinide 2 MG Oral Tablet repaglinide rosiglitazone 2 MG Oral Tablet rosiglitazone 4 MG Oral Tablet rosiglitazone 8 MG Oral Tablet rosiglitazone saxagliptin 2.5 mg oral tablet saxagliptin 5 mg oral tablet sitagliptin 100 MG Oral Tablet sitagliptin 25 MG Oral Tablet sitagliptin 50 MG Oral Tablet sitagliptin phosphate tolazamide 100 MG Oral Tablet tolazamide 250 MG Oral Capsule tolazamide 250 MG Oral Tablet tolazamide 500 MG Oral Tablet tolazamide tolbutamide troglitazone 200 MG Oral Tablet troglitazone 300 MG Oral Tablet troglitazone 400 MG Oral Tablet vildagliptin 100 MG Oral Tablet vildagliptin 50 MG Oral Tablet Diabetes Lab Test Codes & Names Diabetes Lab Test Codes LOINC Codes 17856-6 4548-4 4549-2 SNOMED Codes 33601001 40402000 43396009 117346004 165680008 259689004 259690008 313835008 408254005 CPT Codes 83036 83037 Diabetes Lab Test Names A1c Glucohemoglobin measurement glycosylated hemoglobin A Page 30 of 34 glycosylated hemoglobin glycosylated hemoglobin-c fraction HbA1c test HbA1c Hemoglobin A1c test Hemoglobin A1c total glycosylated hemoglobin level total glycosylated hemoglobin Encounter Codes & Names Acute Encounter Codes & Names Acute Encounter CPT Codes 99221 99222 99223 99231 99232 99233 99238 99239 99251 99252 99253 99254 99255 99291 99281 99282 99283 99284 99285 Acute Encoutner ICD-9-CM Codes 99221 99222 99223 99231 99232 99233 99238 99239 99251 99252 99253 99254 99255 99291 99281 Page 31 of 34 99282 99283 99284 99285 Acute Encounter Names Acute Inpatient Care Unit Acute Inpatient Care Acute Inpatient Unit Acute Inpatient Critical Care Unit Critical Care ED Emergency Department Emergency Room encounter acute inpt encounter ED encounter non-acute inpatient encounter outpatient Inpatient Mental Health Department Inpatient Mental Health Inpatient Mental Health Unit Inpatient Substance Abuse Department Inpatient Substance Abuse Unit Inpatient Substance Abuse Inpatient Surgery Intensive Care Unit Intensive Care Non-Acute Encounter Codes & Names Non-Acute Encounter CPT Codes 99304 99305 99306 99307 99308 99309 99310 99315 99316 99318 99324 99325 99326 99327 99328 99334 99335 Page 32 of 34 99336 99337 99201 99202 99203 99204 99205 99211 99212 99213 99214 99215 99217 99218 99219 99220 99241 99242 99243 99244 99245 99341 99342 99343 99344 99345 99347 99348 99349 99350 99384 99385 99386 99387 99394 99395 99396 99397 99401 99402 99403 99404 99411 99412 99420 99429 Page 33 of 34 99455 99456 Non-Acute Encounter Names Non-Acute Inpatient Non-Acute Inpatient Unit Non-Acute Inpatient Care Sub-Acute Inpatient Care Unit Sub-Acute Inpatient Unit Sub-Acute Inpatient Care Sub-Acute Inpatient Care Unit Nonacute Inpatient Nonacute Inpatient Unit Nonacute Inpatient Care Subacute Inpatient Care Unit Subacute Inpatient Unit Subacute Inpatient Care Subacute Inpatient Care Unit Outpatient Office Visit Ophthalmology Page 34 of 34