To: Genetics Summer Assignment 1. I would like you to find three current events (within a year) articles about genetics/genetic engineering. You may get these articles from newspapers or magazines or from reputable sites on the Internet. If they are internet articles, it must be the full article, not a highlight summary. Write a 1-page summary of the article and response (reactions/thoughts) for each of your articles (12- point font, double-spaced), and be prepared to discuss the most interesting article in class during the first week of school. The summaries are due on the first day of school. Please include a copy of the article. 2. You will be: a. Making a chromosome map by identifying the location of 50 genes b. Choosing 5 genes which have associated disorders and prepare an original short report on each of the 5 disorders (3-4 paragraphs) – These genes must be on your assigned chromosome. Chromosome____________________________ To find the location of the genes, you will use gene maps that have already been done and are available on the internet. Click on the link http://web.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/index.shtml This explains how to use the site Online Mendelian Inheritance in Man. Don’t get frustrated. Really explore the site, not only the OMIM chromosome link, but the other links as well. You may also look at other data banks for additional information – there are a number of sites that may be useful to you. http://www.ncbi.nlm.nih.gov/books/NBK22266/ The chromosome must be your original work – no “cut and paste”. It should be neatly drawn and/or decorated. The gene name must be spelled out in addition to the address/location. The chromosome project is due on the first day of school. 3. You should be familiar with some of the terms used in the course. On the back of this paper is a list of terms – expect a quiz on these terms within the 1st week. There are 2 books we will be discussing throughout the course. You will need to purchase the books “Genome” by Matt Ridley and “Sex, Drugs & DNA: Science’s Taboos Confronted” by Michael Stebbins. Both books can be found on Amazon for a reduced cost. You DO NOT have any required reading out of this book during the summer. Book club Friday will begin the second or third week of school, so you will need to have purchased your books in advance. Have a wonderful summer!! If you have any questions, please get in touch with me. My email address is kbacon@lrhsd.org, or you can leave a message for me through the school (609-654-7544 ext 8317). To: Allele Autosome Chromosome Diploid/Haploid DNA/RNA Dominant/Recessive Homozygous/Heterozygous Gene Restriction enzymes Gene pool Genome Genotype/Phenotype XX/XY Germline/Somatic Mutation Gel electrophoresis PCR Sex chromosome PCR Microarrays Transformation Model organisms Prokaryote/eukaryote Vortex Centrifuge Thermal cycler Incubator UV Transilluminator Micropipette Colony/lawn protein