Essay The essay is worth 10% of the overall mark The word limit is 1000 words not including references You can add Figures or Diagrams The deadline will be in late January (exact data to be decided) You can write the essay on any one of the following three topics: Methods for genetic sequencing The sequence of bases in a DNA molecule determines the amino acid sequence of the generated protein which in turn confers its function. Gene sequencing is the method of determining the sequence of bases. In recent years, new methods have been developed for gene sequencing which has made the process so quick and cheap; it may soon be possible to routinely obtain the complete genetic sequence of individual humans. In this essay, review the current state of the art methods for obtaining DNA sequences, explaining how they work and what are their pros and cons. What are the potential future directions for this field? The Lipid Raft Hypothesis It is known that 3-component mixtures of saturated and unsaturated lipids and cholesterol can form co-existing liquid-ordered and liquid-disordered phases in model membrane bilayers. The lipid raft hypothesis is that ordered-phase domains (the rafts) exist in the plasma membranes of live cells, and float in the liquid-disordered “sea” of the rest of the membrane. These rafts could act as platforms for cell signalling molecules, regulating membrane protein diffusion and interactions. Review the history and current state of the art of the Lipid Raft Hypothesis. What are the physical properties of rafts now thought to be? Nanotechnology in the cosmetic industry Nanotechnology is the manipulation of objects on the scale of nanometers. This may include the generation of nano-particles, liposomes and drug delivery systems. Nanotechnology in the cosmetic industry is now a multi-billion dollar industry and now includes technology as diverse as nanoparticles to enhance UV absorption in Sun block to nano-scale emulsions in shampoo. Review the current state of the art of nanotechnology in the cosmetic industry and suggest what the technologies of tomorrow might allow.