DBB conference 15 -16 September 2014 Seglarhotellet, Sandhamn, Stockholm Archipelago PROGRAM MONDAY, SEPTEMBER 15 08.48- Buss 433/434 from Slussen – Stavsnäs 09.40- Boat (Dalarö) from Stavsnäs – Sandhamn 10.45- Arrival to Sandhamn 10.45-11.45 Check in 11.45-12.45 Lunch 12.45-12.50 Opening of the conference (Lena Mäler) 12.50-13.00 Organisatory remarks (Arne Elofsson/Elzbieta Glaser) Plenary lecture 1 (Chairman: Dan Daley) 13.00-13.40 Siv Andersson - Evolution of small bacterial genomes Session 1 (Chairman: Tara Hessa, Pedro Teixeira) 13.40-14.00 Scarlett Szpryngiel - Biophysical characterization of membrane-interacting GT-B glycosyltransferases 14.00-14.20 Kiavash Mirzadah - Increasing expression of membrane proteins in Escherichia coli by harmonising the coding sequence with the vector 14.20-14.40 Erika Spånning – Dual targeting of organellar proteins 14.40-15.00 Ola Nilsson - Detection of co-translational folding of the zinc finger ADR1 by using a SecM-derived stalling sequence. 15.00-15.30 Coffee break 15.30-16.30 Poster session 1 Plenary lecture 2 (Chairman: Martin Ott) 16.30-17.10 Elias Arnér - The Mammalian Selenoprotein Thioredoxin Reductase 1 as a Key Regulator of Cellular Signaling Pathways Session 2 (Chairman: Mikaela Rapp, Daniel Lundin) 17.10-17.30 Gustav Berggren - Discovery of antimicrobial ribonucleotide reductase inhibitors by high-throughput screening 17.30-17.50 Elin Lundin - Padlocking in situ - Finding molecular patterns in tissues 17.50-18.10 Manfred Heublein - Mitochondrial -ketoglutarate dehydrogenase: The novel core component Kgd4 recruits the E3 subunit to the complex 18.10-18.30 Johan Berg - Single Molecule Studies of Respiratory Enzymes and Supercomplexes under Constant Turn-over Conditions at Well Defined Redox States 18.30-18:50 Chenge Li - Discovery of Selective GPCR Ligands from Docking Screens: Is Homology Modeling Accurate Enough?" 19.00-20.30 Dinner 20.30-21.30 Poster session 2 TUESDAY, SEPTEMBER 16 Plenary lecture 3 (Chairman: David Drew) 08.40-09.20 Maria Selmer - Structural mechanisms of RNA modification and antibiotic resistance in bacterial translation Session 3 (Chairman: Beata Kmiec, Kimmo Rantailainen) 09.20-09.40 Heusser Stephanie – Online Dating on the Molecular Level - Finding New Agents with General Anesthetic Actions at Ligand-Gated Ion Channels 09.40-10.00 Abelein Axel - Transient binding of Zn2+ redirects amyloid β peptide monomers from fibril formation 10-10.30 Coffee break Session 4 (Chairman: Sara Light, Pål Stenmark) 10.30-10.50 Hena Sandhu - How is magnesium homeostasis achieved in cells? Structural and biochemical studies of a prokaryotic Mg2+ channel to unravel principles of Mg2+ transport and homeostasis 10.50-11.10 Michel Micro - PconsFold: Improved contact predictions improve protein models 11.10-11.30 Julia Griese - Assembly of an oxygen-activating heterodinuclear Mn/Fe cofactor 11.30-11.50 Uzdavinys Povilas - Structure and function of Na+/H+ antiporter 11.50-12.10 David Rodriguez - Discovery of Selective GPCR Ligands from Docking Screens: Is Homology Modeling Accurate Enough?" 12.10- Lunch 13.30- Departure boat (Dalarö) Sandhamn-Stavsnäs 14.40-15.34 Buss 433/434 Stavsnäs - Slussen