Biology Class Notes Lesson 22 Genetics Objective: 3.2.2 Genetics: The study of traits and patterns of inheritance for the purposes of classification and medical advancement. Common Terms Allele: A letter that represents the type or form a gene takes. Ex: B=Brown, b = blue eyes, T = tall, t = short Genotype: The combination of alleles an organism inherits, one from each parent. Ex: CC, Cc or cc. Phenotype: The form of the trait the organism displays. Ex: Green eyes, black hair, attached earlobes, etc. Related Laws: Law of Segregation: Offspring get one allele for each trait from each parent. Law of Independent Assortment: Genes for traits on different chromosomes separate independently/randomly. Dominant and Recessive Traits/Genes *When paired up, one of the two traits is usually dominant. Dominant: The allele/trait that is expressed. (abr. w/ capital letters) Recessive: The allele/trait that is not expressed. (abr. w/ lowercase letters) Trait Dominant Gene Recessive Gene Hair Type (letter T/t) Curly Hair (TT or Tt) Straight Hair (tt) Hair Color (letter C/c) Dark (CC or Cc) Light (cc) Earlobe (letter E/e) Free (EE or Ee) Attached (ee) Allele Combinations Homozygous: Having two of the same alleles for a trait. Ex: Homozygous Dominant (DD) and Homozygous Recessive (dd). Heterozygous: Having one dominant and one recessive allele for a trait (Dd). *The dominant allele is expressed with combos DD or Dd, and the recessive allele is expressed only with combo dd. Mendelian Genetics Gregor Mendel (1800’s Austrian Monk) Employed true breeding which produced pure-bred (i.e genetically identical through self-pollination) pea plants for his cross pollination experiments. *True bred genotypes are homozygous (PP or pp) Green pods (PP) x Yellow pods (pp) = All Green Pods F2? Test Cross Accomplished by crossing an individual with a known genotype with one that has an unknown genotype. Ex: Assume red flower color is dominant over white flower color. If a homozygous recessive individual (rr) is crossed with individual that could be either homozygous dominant (RR) or heterozygous (Rr), and all the offspring are red, what must have been the genotype of the unknown individual? Other Traits Examined by Mendel Intermediate Traits Traits that are not clearly dominant or recessive. They may have more than two alleles. They may be controlled by more than one gene. Incomplete Dominance Neither allele is dominant A heterozygous (Cc) genotype produces a phenotype that is a blend of the forms of a trait. Ex: Red and white flowers crossing to produce pink. Codominance Both alleles for a trait are phenotypically expressed in a heterozygous offspring Both alleles are expressed equally Ex: Variegated Plants Multiple Alleles An organism can have only two alleles for a trait, but more than two possible alleles exist in the population. Ex: Blood types: A, B, O – Genotypes can be: AA, AB, BB, BO, AO, OO – A and B are also codominant. Polygenic Traits Traits controlled by two or more genes Ex: Skin Color or height Sex Linked Traits Traits that are determined by the alleles on the sex chromosomes. Most are recessive and are carried on the X chromosome. Therefore, males who have the trait will express it, but females (which have two X chromosomes) can carry and pass on the trait without expressing it. Key Words: Alleles Dominant Recessive Homozygous Genotype Phenotype True-breeding Law of segregation Law of independent assortment Incomplete dominance Codominance Multiple alleles Polygenic trait Sex-linked trait Karyotype