Hector Nuno
31 Monte Verano Ct. ● San Jose California, 95116
(408) 210-8029
E-mail: hectornuno@yahoo.com
QUALIFICATIONS
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Professional Experience in Chemical Engineering
Experience Working with Drug Delivery Technology (Including PEGylation Chemistry)
Laboratory Experience Organic/ Inorganic Techniques (Including Colloidal Systems)
Chemical Synthesis of Nanoparticles
Experience in Aseptic Lab Techniques, PCR Thermocyclers, Autoclave, Electrophoresis,
Handling Chemicals, Molecular Biology and Laboratory Equipment
Clean Room Knowledge
Extensively Trained in SEM and Knowledge in Analyzing TEM and AFM Data
Interacted Heavily with SPR, UV-Ozone, UV-Spectroscopy, IR Spectroscopy,
Fluorescence Spectroscopy, Spin Coating, Metal Vapor Deposition, Contact Angle
Measurements, Ellipsometry
Research and Development (R&D), Scale up
Experience Creating Fluidic Technology for Surface Plasmon Resonance Biosensors
Managing Laboratory Activities
Training Experience of Undergraduate Students
Experience Working Under a Regulated Environment
Excellent Presentation Skills, Research Paper Writing
Strong Leadership Skills and Abilities to Build Collaborative Teams
Strong Analytical and Organizational Skills
Simulation Programs (Sim-Sci, Super Pro), Data Acquisition and Data Analysis
(Polymath, Origen)
Experience with Microsoft Word, Excel and PowerPoint
Bilingual (Spanish/English)
EDUCATION
2010
M.S. DEGREE, CHEMICAL ENGINEERING
SAN JOSE STATE UNIVERSITY, San Jose, CA
Recipient of the “Outstanding Thesis Award” May 2011
2004
B.S. DEGREE, CHEMISTRY/BIOCHEMISTRY
SAN JOSE STATE UNIVERSITY, San Jose, CA
EXPERIENCE
March08-Sep10
IBM ALMADEN RESEARCH CENTER, San Jose, CA
Research Associate (Thesis Work)
Templated Core-Shell Silica Nanoparticles
 Key Contributor for the creation of a new class of complex core-shell silica nanoparticles
 Generated dye-occluded particles, and developed methods for silica encapsulation
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Devised and performed methods for size control to release or retain
pharmaceuticals/dyes that can be beneficial for therapeutic areas
Chemically modified the surface to generate resuspendable biocompatible particles
(Surface tags/markers, PEGylation chemistry)
Characterized particles with Fluorescence microscopy, SEM, TEM, AFM, DLS, UV-vis,
IR, NMR, Dialysis, Solvent Solubility
Surface Plasmon Resonance Biosensor
 Constructed organosilicate SPR-based biosensor for ex-vivo bio-applications
 Created thin films using Chemical Vapor Deposition (CVD)
 Nanostructured thin films with random or ordered porosity (Block-copolymer chemistry)
 Formulated methods to generate an antifouling surface using PEG polymers
 Tested the antifouling properties with bovine serum albumin (BSA)
 Characterized the biosensors with SEM, TEM, AFM, SPR, Ellipsometry, Contact Angle
Measurements, UV-Ozonolysis
 Delivered weekly results to the management team via Power Point presentations
June02-Dec03
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SAN JOSE STATE UNIVERSITY, San Jose, CA
Undergraduate Research
Achieved the mutation Gln317Ala using site directed mutagenesis in the ligand binding
domain of the nuclear Vitamin D Receptor
Gained knowledge in primer design, PCR, restriction digest, ligation, cloning
transformation, plasmid isolation and purification
Learned sterile techniques to isolate/transfer microorganisms to maintain cell cultures
Conducted enzymatic reaction to isolate genes characterized by gel-electrophoresis
Use radioactive isotopes to perform DNA-sequencing using acrylamide gels.
ACOMPLISHMENTS
Master Thesis Award
-Master Thesis “Functionalized Silica Nanostructures for Biosensing Applications” received the
“Outstanding Thesis Award” May 2011 San Jose State University
Patent
-Results of Master Thesis are included in patent application #ARC920100093US1, IBM
Almaden Research Center, San Jose, CA
Seminars
- “Star polymer templated, dye occluded, functionalized silica nanoparticles for optoelectronic
applications, 239th ACS National Meeting, San Francisco, California (2010)
- “Construction of Mutant Gln317Ala in the Ligand Binding Domain of the Nuclear Receptor for
1α,25-Dihydroxy-Vitamin D3 by Site Directed Mutagenesis”, New Orleans, Louisiana (2002)
Education
- Two time Dean Scholar (2003, 2004)
- Outstanding achievement in physic award by the Department of Physics, SJSU (2003)