March 2013 Janet P. Tate, ScD CURRICULUM VITAE Janet P. Tate, ScD Yale University Address: VA Connecticut Healthcare System 950 Campbell Ave, 11-ACSLG West Haven, CT 06516 Phone: (203) 932-5711 ext 5371 Fax: (203) 937-4926 Email: Janet.Tate2@va.gov Education BS Southern Connecticut State University MPH University of Connecticut 1997 ScD Harvard University 2010 1981 Career/Academic Appointments 1981-84 Development Chemist, MacDermid Inc., Waterbury, CT 1986-90 Analytical Chemist, Uniroyal Chemical, Naugatuck, CT 1990-92 Product Quality Analyst, Chemtura, Middlebury, CT 1992-94 Business Analyst, Chemtura, Middlebury, CT 1996-97 Research Fellow (0.4 FTE), Dept. of Community Medicine, Univ. of Connecticut Health Center 1997-07 Senior Health Information Analyst, Qualidigm, Rocky Hill, CT 2008-2011 Consultant statistician, Veterans Aging Cohort Study, Yale University, New Haven, CT 2008-2011 Consultant statistician (<0.1 FTE), Dept. of Cardiology, Univ. of Connecticut Health Center 2011Associate Research Scientist, Department of Internal Medicine, Yale Univ. School of Medicine Professional Honors & Recognition 1992 Quality Award, Uniroyal Chemical, Product excellence team concept 1991 Technical Achievement, Uniroyal Chemical, Naugard Q characterization and production increase 1990 Tech Expo, Best Paper, Uniroyal Chemical, Characterization of TMQ antioxidants 1987 Technical Achievement, Uniroyal Chemical, Reduced variability of Vitavax assay method Grant History A. Current Grants Agency: NIH/ NIAAA I.D. #: 1U24AA020794 Title: Consortium to improve OutcoMes in HIV/AIDS, Alcohol, Aging, & Multi-Substance Use P.I.: Amy Justice, MD, PhD, MSC Role: Director Biostatistics Percent effort: 20% Direct costs per year: $ 757,364 Project period: 09/1/2011 – 08/31/2016 1 March 2013 Janet P. Tate, ScD Agency: NIH/ NHLBI I.D. #: 3R01HL095136-04S1 Title: Cardiovascular Disease Mechanisms in HIV Infected and Uninfected Veterans - Supplement P.I.: Matthew Freiberg, MD Role: Biostatistician Percent effort: 10% Direct costs per year: $128,513 Project period: 09/25/2008 – 06/30/2013 Agency: NIH/ NIAID I.D. #: 5U01A1069918 Title: North American AIDS Cohorts Collaboration on Research and Design P.I.: Richard Moore, MD, MHS Role: Biostatistician Percent effort: 15% Direct costs per year: $49,172 Project period: 07/01//06 – 06/30/16 Agency: NIH/ NIAAA I.D. #: U24 AA022007-01 Title: The Operations Research Collaboration for Alcohol Abuse and AIDS: ORCAAA P.I.: R. Scott Braithwaite, MD, MSc, FaCP Role: Site PI, Biostatistician Percent effort: 25% Direct costs per year: $47,821 Project period: 09/1/12 – 8/31/17 Agency: NIH/ NIDA I.D. #: R01DA035616 Title: Using the VACS Index to track health outcomes associated with changes in drug use P.I.: David Fiellin, MD Role: Biostatistician Percent effort: 25% Direct costs per year: $530,959 Project period: 04/01/13 - 02/29/16 B. Past Grants Agency: NIH I.D. #: R01HS018372-02 Title: Clinical Prediction of Hepatotoxicity&Comparative Hepatic Safety of Medications P.I.: Vincent LoRe III, MD, MSCE Role Statistician Percent effort: 10% 2 March 2013 Janet P. Tate, ScD Direct costs per year: $ 70,000 Project period: 08/01/11 - 07/31/12 Agency: NIAAA I.D. #: 5U10AA013566-10 Title: Alcohol Associated Outcomes Among HIV+/- Veterans P.I.: Amy Justice, MD, PhD, MSC Role Consultant Percent effort: 99.9% Direct costs per year: $ 2,519,900 Project period: 09/30/06 - 8/31/11 Agency: NIEHS ID #: 2 T32 ES07069-26 Title: Training Program in Environmental Epidemiology PI: David Christiani, MD, MPH, MS Role: Student Project period 9/1/2005 – 8/31/2007 Agency: ID# Title: PI: Role: Project period: Department of Public Health, State of Connecticut 2009-0914 for Biomedical Research, 10/1/2009-6/30/2010 Development of a new blood test for patients with heart failure Bruce Liang MD Consultant Bio-statistician 10/1/2009-6/30/2010 Lectures, Courses, Web-based Education 2012 Introduction to Biostatistics in Clinical Research (2 lectures), Yale University School of Medicine 2011 Interpretation of diagnostic tests, Yale University School of Medicine Residents, Bridgeport Hospital 2010 Interpretation of diagnostic tests, Yale University School of Medicine Residents, Bridgeport Hospital 2010 Power and sample size, University of Connecticut School of Medicine, Cardiology and Pulmonary Fellows 2008 Principles of Epidemiology, University of Connecticut MPH program, Farmington, CT 2006 Principles of Epidemiology, University of Connecticut MPH program, Farmington, CT 2005 Epidemiology Research Appraisal, University of Connecticut MPH program, Farmington, CT 2005 Principles of Epidemiology, University of Connecticut MPH program, Farmington, CT 2003 Principles of Epidemiology, University of Connecticut MPH program, Farmington, CT 2002 Principles of Epidemiology, University of Connecticut MPH program, Farmington, CT Bibliography 1. Gregorio DI, Walsh SJ, Tate JP. Diminished socioeconomic and racial disparity in the detection of earlystage breast cancer, Connecticut, 1986-1995. Ethn Dis. 1999 Autumn;9(3):396-402. 2. Meehan TP, Chua-Reyes JM, Tate J, Prestwood KM, Scinto JD, Petrillo MK, Metersky ML. Process of care performance, patient characteristics, and outcomes in elderly patients hospitalized with communityacquired or nursing home-acquired pneumonia. Chest. 2000 May;117(5):1378-85. 3 March 2013 Janet P. Tate, ScD 3. Graff L, Russell J, Seashore J, Tate J, Elwell A, Prete M, Werdmann M, Maag R, Krivenko C, Radford M. False-negative and false-positive errors in abdominal pain evaluation: failure to diagnose acute appendicitis and unnecessary surgery. Acad Emerg Med. 2000 Nov;7(11):1244-55. 4. Metersky ML, Tate JP, Fine MJ, Petrillo MK, Meehan TP. Temporal trends in outcomes of older patients with pneumonia. Arch Intern Med. 2000 Dec 11-25;160(22):3385-91. 5. McCormick D, Gurwitz JH, Goldberg RJ, Becker R, Tate JP, Elwell A, Radford MJ. Prevalence and quality of warfarin use for patients with atrial fibrillation in the long-term care setting. Arch Intern Med. 2001 Nov 12;161(20):2458-63. 6. Harrold LR, Gurwitz JH, Tate JP, Becker R, Stuart T, Elwell A, Radford M. Physician attitudes concerning anticoagulation services in the long-term care setting. J Thromb Thrombolysis. 2002 Aug;14(1):59-64. 7. Meehan TP, Tate JP, Holmboe ES, Teeple EA, Elwell A, Meehan R, Petrillo MK, Huot SJ. A collaborative initiative to Improve the care of elderly patients with hypertension. Am J Med Qual. 2004 May-Jun;19(3):103-11. 8. Van Hoof TS, Pearson DA, Sherwin TE, Tate JP, Elwell A, Barr JK, Meehan TP. “Lessons learned from performance feedback by a Quality Improvement Organization.” J Healthc Qual 2006; 28:20-31. 9. Holmboe ES, Wang Y, Tate JP, Meehan TP. “The effects of patient volume on the quality of diabetic care for Medicare beneficiaries.” Med Care. 2006 Dec;44(12):1073-7. 10. Meehan TP, Wang Y, Tate JP, Curry M, Elwell A, Petrillo MK, Holmboe ES. “Improving the quality of preventive cardiovascular care provided by primary care physicians: Insights from a U.S. Quality Improvement Organization.” Int J Qual Health Care 2006;18(3):186-194. 11. Holmboe ES, Wang Y, Meehan TP, Tate JP, Ho SY, Starkey KS, Lipner RS. “Association between maintenance of certification examination scores and quality of care for Medicare beneficiaries. Arch Intern Med. 2008 Jul 14;168(13):1396-403. 12. Ohl M, Tate J, Duggal M, Skanderson M, Scotch M, Kaboli P, Vaughan-Sarrazin M, Justice A. Rural Residence Is Associated With Delayed Care Entry and Increased Mortality Among Veterans With Human Immunodeficiency Virus Infection. Med Care. 2010 Dec; 48(12):1064-1070. 13. Womack JA, Goulet JL, Gibert C, Brandt C, Chang CC, Gulanski B, Fraenkel L, Mattocks K, Rimland D, Rodriguez-Barradas MC, Tate J, Yin MT, Justice AC; for the Veterans Aging Cohort Study Project Team. Increased Risk of Fragility Fractures among HIV Infected Compared to Uninfected Male Veterans. PLoS One. 2011 Feb 16;6(2):e17217 14. Lo Re V, Lim JK, Goetz MB, Tate J, Bathulapalli H, Klein MB, Rimland D, Rodriguez-Barradas MC, Butt AA, Gibert CL, Brown ST, Kidwai F, Brandt C, Dorey-Stein Z, Reddy KR, Justice AC. Validity of diagnostic codes and liver-related laboratory abnormalities to identify hepatic decomposition events in the Veterans Aging Cohort Study. Pharmacoepidemiol Drug Saf 2011 Jul; 20(7):689-699. [PMID: 21626605] 15. Park LS, Tate JP, Justice AC, Lo Re V, Lim JK, Brau N, Brown ST, Butt AA, Gibert C, Goetz MB, Rimland D, Rodriguez-Barradas MC, Dubrow R. FIB-4 index is associated with hepatocellular carcinoma risk in HIV-infected patients. Cancer Epidemiol Biomarkers Prev 2011 Dec; 20(12):2512-2517. [PMID: 22028407] 16. Tetrault JM, Tate JP, McGinnis KA, Goulet JL, Sullivan LE, Bryant K Justice AC, Fiellin DA for the Veterans Aging Cohort Study Project Team. Hepatic safety and antiretroviral effectiveness in HIV4 March 2013 Janet P. Tate, ScD infected patients receiving naltrexone. Alcohol Clin Exp Res 2012 Feb; 36(2):318-324. [PMID: 21797892] 17. Justice AC, Freiberg MS, Tracy R, Kuller L, Tate JP, Goetz MB, Fiellin DA, Vanasse GJ, Butt AA, Rodriguez-Barradas MC, Gibert C, Oursler KA, Deeks SG, Bryant K, and the VACS Project Team. Does an index composed of clinical data reflect effects of inflammation, coagulation, and monocyte activation on mortality among those aging with HIV? Clin Infect Dis 2012; Feb 15 (Epub ahead of print). [PMID: 22337823] 18. Tate JP, Justice AC, Hughes MD, Bonnet F, Reiss P, Mocroft A, Nattermann J, Lampe FC, Bucher HC, Sterling TR, Crane H, Kitahata MM, May M, Sterne JAC. The VACS index: An internationally generalizable risk index for mortality after one year of antiretroviral therapy, in HIV-infected individuals. AIDS 2013 Feb; 27(4):563-572. PMID: 23095314. 19. Justice AC, Modur S, Tate JP, Althoff KN, Jacobson LP, Gebo K, Kitahata M, Horberg M, Brooks J, Buchacz K, Rourke SB, Rachlis A, Napravnik S, Eron J, Willig JH, Moore R, Kirk GD, Bosch R, Rodriguez B, Hogg RS, Thorne J, Goedert JJ, Klein M, Gill MJ, Deeks S, Sterling TR, Anastos K, Gange SJ for the NA-ACCORD and VACS Project Teams. Predictive accuracy of the Veterans Aging Cohort Study (VACS) Index for mortality with HIV infection: A North American Cross Cohort Analysis. J Aquir Immune Defic Syndr 2013 Feb; 62(2):149-163. PMID: 23187941. 20. Akgun KM, Gordon K, Pisani M, Fried T, McGinnis KA, Tate JP, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K. Risk factors for hospitalization and medical intensive care unit (MICU) admission among HIV infected veterans. J Aquir Immune Defic Syndr 2013 Jan; 62(1):52-59. PMID: 23111572. 21. Akgun KM, Tate JP, Pisani M, Fried T, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K. Medical Intensive Care Unit (MICU) admission diagnoses and outcomes in HIV-infected and uninfected veterans in the combination antiretroviral era. Crit Care Med 2013; Mar 15 (Epub ahead of print). PMID: 23507717. 22. Oursler KK, Tate J, Gill TM, Crothers K, Brown TT, Crystal S, Womack J, Leaf DA, Sorkin JD, Justice AC. Association of the VACS index with exercise capacity in HIV-infected adults. AIDS Res Hum Retroviruses (in press). Peer Reviewer Journals Pharmacoepidemiology and Drug Safety PLoS ONE Clinical Infectious Diseases 5