Random Surgical/Excisional Biopsies Pathology* Report released: Feb 19, 2015, 04:38 p.m. Specimen collected: Feb 18, 2015, 05:09 p.m. SurgPath Final A) In formalin labeled "anterior neck" is a 0.3 cm in greatest dimension punch of skin. All blocked labeled as A1. B) In formalin labeled "left preauricular" is a 0.3 cm in greatest dimension punch of skin. All blocked labeled as B1. C) In formalin labeled "left neck" is a 0.3 cm in greatest dimension punch of skin. All blocked labeled as C1. D) Received in formalin labeled “abdomen” is an unoriented ellipse of skin with underlying soft tissue measuring 1.5 x 0.8 x 0.7 cm. The specimen is inked on its surgical margins with black ink and the tips are shaved from the specimen and submitted in D1 while the remainder is submitted in D2. E) Received in formalin labeled “left upper thigh” is an unoriented ellipse of skin with underlying soft tissue measuring 1.8 x 1.0 x 0.7 cm. The specimen is inked on its surgical margins with black ink and the tips are shaved from the specimen and submitted in E1 while the remainder is submitted in E2. F) In formalin labeled "left upper arm" is a 0.3 cm in greatest dimension punch of skin. All blocked labeled as F1. G) In formalin labeled "left mid back" is a 0.3 cm in greatest dimension punch of skin. All blocked labeled as G1. A) ANTERIOR NECK B) LEFT PREAURICULAR C) LEFT NECK D) ABDOMEN E) LEFT UPPER THIGH ANTERIOR F) LEFT UPPER ARM G) LEFT MID BACK NEW GROWTH A) Skin, anterior neck, punch biopsy: Benign skin and soft tissue with folliculitis, negative for malignancy. B) Skin, left preauricular, biopsy: Benign skin and soft tissue, negative for malignancy. C) Skin, left neck, punch biopsy: Benign skin and soft tissue, negative for malignancy. D) Skin, abdomen, excision: Benign skin with minimal chronic inflammation, negative for malignancy. E) Skin, left upper thigh, anterior, excision: Benign skin with minimal inflammatory cells, negative for malignancy. F) Skin, left upper arm, punch biopsy: Benign skin with minimal chronic inflammation, negative for malignancy. G) Skin, left mid back, punch biopsy: Pigmentary incontinence with mild superficial inflammation, negative for malignancy. SurgPath Addendum Congo red stain is negative for amyloid (specimen E). SurgPath Outside Slide Review This addendum is issued to report the findings of the skin biopsies B1. "SKIN, ANTERIOR NECK, PUNCH BIOPSY": PERIFOLLICULAR CHRONIC INFLAMMATION. SEE NOTE. B2. "SKIN, LEFT PREAURICULAR, BIOPSY": MILD PERIVASCULAR CHRONIC INFLAMMATION. SEE NOTE. B3. "SKIN, LEFT NECK, PUNCH BIOPSY": MILD PERIVASCULAR CHRONIC INFLAMMATION. SEE NOTE. B4. "SKIN, ABDOMEN, EXCSION": FOCAL INCREASE IN DERMAL MUCIN. SEE NOTE. B5. "SKIN, LEFT UPPER THIGH, ANTERIOR, EXCISION": INCREASE IN DERMAL MUCIN. PERIFOLLICULAR CHRONIC INFLAMMATION. SEE NOTE. B6. "SKIN, LEFT UPPER ARM, PUNCH BIOPSY": MILD PERIVASCULAR CHRONIC INFLAMMATION. SEE NOTE. B7. "SKIN, LEFT MID BACK, PUNCH BIOPSY": EPIDERMIS WITH VACUOLAR CHANGES AND PIGMENT INCONTINENCE. SEE NOTE. NOTE: The changes are subtle. The most remarkable histologic findings in these biopsies are the presence of superficial perivascular inflammation, perifollicular lymphocytic infiltrate associated with vacuolar changes in the epidermis with isolate dyskeratotic cells. Mucin is noted in several biopsies. On balance, the changes raise the possibility of a lichenoid/interface dermatitis such as connective tissue diseases or drug reactions. Clinical-pathologic correlation is necessary. This case has been discussed with the ordering physician.