Ch 1 Arithmetic Needed for Dosage Fractions Decimals Percents Ratios Proportions Ch 2 Interpreting the Language of Prescriptions Abbreviations English SI – Metric System Apothecary Routes of Administration Ch 3 Drug Labels and Packaging How to read drug labels Ch 4 Metric, Apothecary, Household Systems of Measurement Ch 5 Drug Preparations and Equipment to Measure Doses Ch 6 Calculations of Oral Medication – Solid and Liquid forms 1 Ch 7 Liquids for Injection Ch 8 Calculation of Basic IV Drip Rates Microdrips Macrodrips PUMPs Ch 9 Special Types of Calculations Ch 10 Dosage Problems for Infants and Children Is it Safe??? Low range --- High range Ch 11 Dimensional Analysis __10mg__ x __1g___ = 1000mg 1/100 g = 0.01 g Ch 12 Information Basic to Administering Drugs Ch 13 Administration Procedures 2 Ch 1 Arithmetic Needed for Dosage Multiply Divide Add Subtract Order of Operations PEMDAS Parentheses Exponentiations Multiplication Division Addition Subtraction (5+6)^7/8*4 Rule for Rounding (p.11) When the number to be dropped is 5 or more, drop the number and add 1 to the previous number. When the last number is 4 or less, drop the number. Round the following to the nearest hundredth .450 .451 .452 .453 .454 .455 .456 3 .457 .458 .459 Convert Fraction to Decimal: divide the numerator by the denominator Convert any number to Percent: multiply the number by 100 (moving decimal point two places to the right) 0.0045 x 100 = 0.45% 0.045 x 100 = 4.5% 0.45 x 100 = 45% 4.50 x 100 = 450 % 45 x 100 = 4500 % Convert percent to decimal: divide the number (5) by 100 (moving decimal point two places to the left) 650 % /100 = 6.50 65 % /100 = 0.65 6.5 % /100 = 0.065 0.65 % /100 = 0.0065 0.065 % /100 = 0.00065 4 Significant Figures Taken from: http://en.wikipedia.org/wiki/Significant_figures Identifying significant digits 1. All non-zero digits are significant. Example: '123.45' has five significant figures: 1,2,3,4 and 5. 45.6666655555666 15 significant digits 2. Zeros appearing in between two non-zero digits are significant. Example: '101.12' has five significant figures: 1,0,1,1,2. 0.34450078 8 significant 3. All zeros appearing to the right of an understood decimal point and non-zero digits are significant. Example: '12.2300' has six significant figures: 1,2,2,3,0 and 0. The number '0.00122300' still only has six significant figures (the zeros before the '1' are not significant). 15.65000 7 significant 0.000122400 6 significant figures 0.010 2 significant figures 4. All zeros appearing in a number without a decimal point and to the right of the last non-zero digit are not significant unless indicated by a bar. Example: '1300' has two significant figures: 1 and 3. The zeros are not considered significant because they don't have a bar. However, 1300.0 has five significant figures. 2600 2 significant figures (zeros are after non-zero digits AND there is NO decimal point) 5 2600.0 five significant figures 600 1 sf 601 3 sf 600.0 4 sf 0.600 3 sf 0.00600 3 sf 0.000600 3 sf 0.00060 2 sf 0.0006 1 sf Round that number to nearest thousandth = 0.001 Round 0.0004 to nearest thousandth = 0.000 However, this last convention is not universally used; it is often necessary to determine from context whether trailing zeros in a number without a decimal point are intended to be significant. Digits may be important without being 'significant' in this usage. For instance, the zeros in '1300' or '0.005' are not considered significant digits, but are still important as placeholders that establish the number's magnitude. A number with all zero digits (e.g. '0.000') has no significant digits, because the uncertainty is larger than the actual measurement. 1 3 0 0 Thousand hundred ten one 0.1 3 1 3 0 0 Tenth hundredth thousandth ten-thousandth 6 Rounding conventions When rounding to n significant digits, there are a few general rules that are followed:[1] If the digit immediately to the right of the nth significant digit is greater than 5, the number is rounded up. If the digit immediately to the right of the nth significant digit is less than 5, the number is rounded down. If the digit immediately to the right of the nth significant digit is 5 and there are non-zero digits after the 5, the number is rounded up. If the digit immediately to the right of the nth significant digit is 5 and there are no subsequent non-zero digits, there are two commonly-used conventions (see rounding for longer discussion). In 'common rounding', such a digit is always rounded up; in 'unbiased rounding' (also known as 'round-to-even'), it is rounded in whichever direction leaves the nth digit even. For instance, under unbiased rounding, 51.5 would be rounded up to 52, but 54.5 would be rounded down to 54. Ratio and Proportion 1:10 (1/10) one to ten 3:5 :: 4:7 3 is to 5 AS 4 is to 7 3:5 :: X:7 Solve for x!!!! Product of the Outer digits = product of inner digits 3x7=5xX 21=5x X=21/5 (fraction form) X = 4.2 (decimal form) Order: 0.5mg of drug A 7 Supply: A liquid labeled 0.125 mg per 4 mL .5mg = x mL 0.125 mg 4 mL 0.5 mg x 4mL = 16 mL 0.125 mg 10:x :: 12 : 35 Solve for x! 10 x 35 = 12 x X X = 350/12 = 29.16666666 (repeating decimal)=> 29.17 => 29.2 => 29 (rounded to the nearest number) 1a-16 Property tax : value of the house 3000: 250000 1a-23 4 0.16 = 16/100 = 4/25 25 8 1a-20 3 x 12 = 36 4 x 12 48 3+4 = 7 84/7 = 12 Num + dem = 84 3/5 SUM of num and denom = 64 3+5 = 8 64/8 = 8 (multiple needed for num and denom) 3 x8 = 24 5 x8 40 1a-12 lcd for 8, 12, 21 8x1=8 8 x 2 = 16 8 x 3 = 24 12 x 1 = 12 12 x 2 = 24 21 x 1 21 X 2 … 21 X 8 = 168 9 WHEN IN A HURRY: multiply each denominator value with each other to get a common denominator 1a-25 4 (1/5) – 2(2/3) =21/5 - 8/3 = (21x3)/15 - (8x5)/15 = 63/15 – 40/15 = 23/15 = 1 8/15 9dimes:6 quarters -> 90cents/125cents 9d x 2n/d: 6q x 5/q 18 n/30n = 3/5 21/51 = used (51-21) = 30/51 = 10/17 24 hours in a day 16hr/24 = 2/3 1 inch = 24 miles 6 inches = 24 x 6 = 144 mi 1:6 :: 24:x 10 4 + 10 + 6 = 20 m 14/20 500-50=450x(3/5) =270 84/(3/4) = 84/.75 = 112 PRIME NUMBER = any number that can be divisible by 1 and divisible by itself 1, 3, 5 , 7, 11, 13, 17, 19, 23, 29, 31 Area = length x width 3/7 x 2/3 = 2/7 sq ft .375 375/1000 = 15/40 = 3/8 0.000453 = 3 sf 0.000 19 +21 + 20 + 22 + 1 + 10 + 0 .1x + .25(25-x) = 3.55 .1x + 6.25 - .25x = 3.55 -.15x = -2.70 11 X=18 A = LxW P = 2L + 2W = 2(17.8 ft) + 2(12.2 ft) = 35.6 ft + 24.4 ft = 60.0 ft 31 = 361.15 33 = x X= 384.45 Total hours = 45.25 40 hr regular 5.25 hr Pay = 40x15 + 5.25 x 15 x 1.5 = 718.13 .16 -> 16/100 = 4/25 .086 2 sf 86/1000 = 43/500 0.000250 3 sf 0.012560 -> 0.01 nearest hundredth 0.013 nearest thousandth 12 18/119 = .1513 15/98 = .1531 16 oz/1.65 = 26.4 14/1.44 = 9.722 C = 9.60x + 1250.00 X =5050 Cost = 9.6(5050) + 1250 0.3322 - 0.1224 .3322 x .1224 13 http://en.wikipedia.org/wiki/Significant_figures 1. All non-zero digits are significant. Example: '123.45' has five significant figures: 1,2,3,4 and 5. 2. Zeros appearing in between two non-zero digits are significant. Example: '101.12' has five significant figures: 1,0,1,1,2. 3. All zeros appearing to the right of an understood decimal point and non-zero digits are significant. Example: '12.2300' has six significant figures: 1,2,2,3,0 and 0. The number '0.00122300' still only has six significant figures (the zeros before the '1' are not significant). 4. All zeros appearing in a number without a decimal point and to the right of the last non-zero digit are not significant unless indicated by a bar. Example: '1300' has two significant figures: 1 and 3. The zeros are not considered significant because they don't have a bar. However, 1300.0 has five significant figures. However, this last convention is not universally used; it is often necessary to determine from context whether trailing zeros in a number without a decimal point are intended to be significant. Digits may be important without being 'significant' in this usage. For instance, the zeros in '1300' or '0.005' are not considered significant digits, but are still important as placeholders that establish the number's magnitude. A number with all zero digits (e.g. '0.000') has no significant digits, because the uncertainty is larger than the actual measurement. 14