French Society of Anesthesia and Resuscitation In collaboration with: Company resuscitation in French Club ENT anesthesia Club obstetrical anesthesia Association of pediatric anesthetists French-speaking Samu de France French Society of Emergency Medicine Difficult intubation Experts Conference Short text 2,006 Experts Conference - Sfar - 2006 • Chairman of the Conference of Experts Anne-Marie Cros (Bordeaux) • Experts Bruno Bally (Grenoble), Jean-Louis Bourgain (Villejuif), Jean Chastre (Paris), Xavier Combes (Créteil),Pierre Diemunsch (Strasbourg), Marc Fischler (Suresnes), Daniel Francon (Marseille), Yann Hervé (Bordeaux), Samir Jaber (Montpellier), Ollivier Laccourreye (Paris), Olivier Langeron (Paris), Annick Legras (Tours), François Lenfant (Dijon), Bruno Marciniak (Lille), Gilles Orliaguet (Paris), Didier Pean (Nantes), Patrick Ravussin (Sion), Martine Richard (Grenoble), François Sztark (Bordeaux). Experts Conference - Sfar – 2006 This expert meeting is an update of the expert conference organized by the Society French Anesthesia and Intensive Care (Sfar) in 1996. It was organized and took place accordance with the methodology developed by Sfar. The president of the conference was designated by the Committee and was the reference group of experts in collaboration with the committee. The experts worked in sub-groups for each question. They developed the recommendations after analysis and synthesis of the literature. References have been analyzed with the grading scale established by the Committee repositories. Recommendations have were discussed in plenary and approved by all the experts either unanimously or by a majority two thirds. FORCE RECOMMENDATIONS The letters in brackets represent the levels of recommendations resulting from the analysis of literature. • Grade A: two studies (or more ...) Level I • Grade B: a study level I • Grade C: study (ies) Level II • Grade D: a study (or more ...) Level III • Grade E: Studies Level IV or V Question 1 What are the predictors of difficult intubation and mask ventilation difficult? Definition Intubation is difficult if it requires more than two laryngoscopy and / or implementation of an alternative technique after optimization of the position of the head, with or without laryngeal manipulation external. Mask ventilation is difficult: 1) it is impossible to get a chest expansion sufficient or tidal volume greater than the dead space (3 ml / kg), a plot capnography identifiable to maintain SpO2> 92% 2) it is necessary to use oxygen more rapid times call another operator 3) if the insufflation pressure is greater than 25 cmH2O Screening for difficult intubation (DI) and difficult mask ventilation (DMV) must be systematic and documented whenever intubation is planned or likely (consultation Anesthesia, ICU admission). In emergency conditions, screening is more difficult but it should be done whenever possible. Predictive criteria Predictive criteria of DMV Age greater than 55 years, a body mass index (BMI)> 26 kg/m2, lack of teeth, mandibular protrusion limiting the presence of snoring and beard were found as predictors of DMV (grade C). The presence of two of these factors is predictive a DMV. The risk of ID multiplied by 4 is difficult in patients with a DMV (grade D). Experts Conference - Sfar – 2006 Predictive criteria ventilation impossible Thyromental a distance <6 cm and the presence of snoring are predictive criteria of ventilation impossible (grade C). Prediction criteria ID The following criteria are predictive of ID, it is recommended to search: history of ID, Mallampati class> 2, thyromental distance (DTM) <6 cm mouth opening <35 mm (grade C). It is also advisable to seek the mandibular mobility (lip bite test) mobility of the cervical spine (angle made by the head fully extended on the neck and bending maxima above 90 °) (E grade). Certain clinical situations increase the risk of ID: a BMI> 35 kg/m2, an apnea Obstructive sleep apnea (OSA) with neck> 45.6 cm, cervicofacial disease (grade D) and pre-eclampsia (grade E). In children the Mallampati classification is not validated (grade E). The prediction criteria IDs are facial dysmorphism, a DTM <15 mm in the newborn infant 25 mm and <35 mm in children less than 10 years, a mouth opening less than three fingerbreadths Child and snoring at night with or without OSA (gradeE). ID prediction criteria in the context of emergency Recommended criteria should be sought wherever possible, but they are not adapted to the context of the emergency. Some situations should alert the operator: trauma cervicofacial (spine trauma, facial trauma), ENT pathology (cervicofacial or oropharyngolaryngée) and the presence of facial burns (grade E). Question 2 Arterial oxygen desaturation and maintaining oxygenation during intubation. All patients should be préoxygénés, especially when an ID and / or VMD planned (grade C) and when patients are at risk of desaturation during intubation. The risk factors desaturation during intubation are: emergency intubation with induction rapid sequence (SRI), a VMD predictable, predictable ID, obesity and pregnancy, infant and newborn child ASA class 3 or 4, the child and the child with buzzer tract infection upper airways (VAS). Finally, the elderly and chronic bronchopathe are also at risk desaturation (grade D). The obese, pregnant women, infants, children with upper airway infection and insufficient breathing preoxygenation may desaturate despite good conduct (grade A). In obese patients, children and pregnant women, due to the decrease in FRC, denitrogenation is faster but the apnea time is shorter (Grade B). Preoxygenation maneuvers must be performed with a mask sealed gas flow sufficient and appropriate size ball (grade D). FEO2 monitoring is recommended, anesthesia, as well as monitoring of SpO2 (grade E). It is recommended that preoxygenation with FiO2 three minutes to 1 adult (grade B) and two minutes in children (grade C), or by asking the patient to achieve eight deep breaths with a flow rate of 10 l / min of oxygen for one minute (grade C). Experts Conference - Sfar – 2006 Pregnant women, the technique of four vital capacity is for 30 seconds alternative to the standard preoxygenation (grade D). In obese patients, the half-sitting position is recommended during oxygenation (grade D). In respiratory failure it is recommended to extend the preoxygenation under control FEO2 (grade D). After induction, the cannulation oropharyngeal is recommended because it facilitates ventilation mask (grade C). Use the main circuit is recommended because it allows monitoring of exhaled gases, the spirometry and insufflation pressures (grade D). Mask ventilation in pressure or volume controlled using the main circuit respirator is a practice to be encouraged (grade D). It is recommended to ventilate a patient whose SpO2 falls below 95%, even if it is full stomach (grade D). Question 3 What local anesthetic techniques, locoregional and general anesthesia? Place in the context Sedation and local anesthesia with intubation fiberscope Sedation or analgesia associated with ALR or AL enhance patient comfort and hemodynamic parameters (grade E). Maintaining spontaneous ventilation is a must, especially if mask ventilation is expected difficult (grade E). Sedation or analgesia bad behavior can make airway management more difficult (Grade E). Propofol and remifentanil administered continuously are the agents of choice (grade C). They should be titrated and administration to target concentration is recommended (grade C). The initial concentration is low and gradually increased in increments until the effect sought (grade C). Target concentrations are based pharmacokinetic models used. For propofol target concentration at the site of action of 2 mg / ml may be recommended with the Schnider model, it is 1.5 ng / ml for remifentanil with the Minto modelSchnider (grade D). The joint administration of these two agents is not recommended due to the increased risk of apnea (grade C). The inhalation anesthesia with sevoflurane is the reference method in children. It is also an alternative in adults (grade D), the Fesevo should be titrated according to the desired effect (grade E). The risk of this technique is the loss of freedom that VAS affect the administration of sevoflurane (grade E). Local anesthesia can be performed either with layered techniques, or with an aerosol of lidocaine to 5% with an oxygen flow rate of 5 l / min (Grade D). The maximum dose is 4 to 6 mg / kg in adults and 3 mg / kg in children. Topical anesthesia of the nose must be associated with a vasoconstrictor. The only recommended blocks are block bilateral laryngeal nerves and block tracheal injection lidocaine through the membrane thyroid intercrico-thyoid (E grade). Experts Conference - Sfar – 2006 Predictable anesthesia ID (excluding fibro optic) General anesthesia may be considered depending on the context (grade D). Choice or not maintaining spontaneous ventilation must consider the possibility of mask ventilation and use oxygenation techniques recommended (grade E). The depth of anesthesia and relaxation muscle must be sufficient to optimize intubating conditions (grade D). Anesthesia should be rapidly reversible (grade E). Propofol and sevoflurane are the agents of choice in the absence of airway obstruction may (grade C). The addition of an opioid optimizes intubation conditions but with a higher risk respiratory depression and apnea (grade C). The administration of agents to target concentration is recommended (grade C). If neuromuscular blockade is required, only succinylcholine may be recommended in the absence of contra-indication (grade C). In the case of a difficult intubation unplanned Depth of anesthesia and muscle relaxation sufficient time must be maintained that continued intubation maneuvers (grade E). In children, The inhalation anesthesia with sevoflurane is the reference technique against a predictable ID (grade D). The establishment of an intravenous line before induction is recommended (grade E). the depth of anesthesia and muscle relaxation must be sufficient to prevent the risk laryngospasm (grade E). Emergency medicine and resuscitation Apart from cardio-respiratory arrest, intubation should be performed after general anesthesia (grade E). The persistence of laryngeal reactivity degrades intubation conditions and increases the risk of serious complications (grade E). The anesthesia must be performed using a rapid sequence induction (grade B). Etomidate and Ketamine is recommended (grade D). Curare of choice is in the absence of succinylcholine contraindication (grade E). The anesthesia must be maintained and deepened if the patient shows signs of revival. A new injection of succinylcholine may be performed if the patient shows signs of reversal compromising intubation (grade E). Question 4 What equipment for intubation and ventilation? Composition of difficult intubation trolley. The choice of devices constituting a trolley ID must consider algorithms Team anesthesia and must cope with all situations. Training of all operators likely to use is mandatory (grade E). A metal blade must be preferred to a plastic blade disposable if laryngoscopy under difficult or emergency intubation (grade C). Experts Conference - Sfar – 2006 To perform a transtracheal oxygenation, it is recommended to use only equipment designed and validated for this purpose (grade E). The use of disposable equipment should be privileged level of technical performance and safety in use equivalent to that of the reusable devices. Material support an ID must be grouped in a cart or in a suitcase easily identifiable and can be used at any time of the day and night (grade E). The composition of trolley ID recommended by the panel is attached. In pediatrics, the material must be adapted to the size of the child, the infant straight blade Miller may be useful. The laryngeal mask intubation (PWM Fastrach types) can be used from 30 kg. Oxygenation transtracheal and cricothyrotomy are not recommended in very young children (grade E). A set of cricothyroidotomy is recommended in case of medical emergency ID (grade E). Question 5 Strategies and algorithms Strategy management can anticipate a critical situation. This management strategy load is centered on maintaining oxygenation of the patient. Faced with an ID provided must anticipate possible difficulties with oxygenation and ensure the availability of resources to maintain during intubation maneuvers: mask ventilation and / or technical assistance. Of decision algorithms intubation and oxygenation were developed. They allow taking responsible for these different clinical situations: planned or unplanned ID and VMD. They are presented in the appendix. Several important points should be noted. The awakening of the patient or the deferral of intervention must be considered at each stage (grade E). The call for help in the early stages of the algorithm is recommended (grade E). It is recommended not to intubate persist and move to the next step after two failures and do not forget to maintain oxygenation between attempts (grade E) It is not recommended to consider the practice of laryngoscopy to assess the real difficulty ID of a scheduled without a strategy planned care (grade E). So it is not recommended to consider the creation of a ALR without providing an alternative in case of failure, the airway control in case of difficulty oxygenation and delaying surgery if the requirements to achieve a sedation are not met. It is recommended to inform the patient of the occurrence of difficult intubation or ventilation mask and mention in the medical record. As part of the emergency, the SRI with Sellick maneuver is the reference technique (grade C). Cricothyroidotomy is preferred transtracheal oxygenation (grade D). The intubation Obstetrics posed by the dual problem of inhalation risk and the risk of fetal distress. Oxygenation should be preferred (grade D). Resuscitation, oxygenation should be encouraged even at the expense of inhalation risk (grade E). The fiberscope is recommended in the presence of a foreseeable difficulty of intubation (grade E). In this context, noninvasive ventilation may be interesting (Grade D). Experts Conference - Sfar – 2006 Question 6 Extubation: Extubation criteria. Management of risk situations Respiratory complications are the most frequent cause of postoperative reintubations (grade C). The complications of extubation are most often related to obstruction mechanical airway or respiratory dysfunction (grade D). After an ID, extubation should be performed in the presence of a senior physician (grade E). Conventional extubation criteria must be met and especially a complete block reversal confirmed by a T4/T1 ratio higher than 90% (grade D). The leak test is not predictive of extubation anesthesia risk (grade D). The implementation of a preventive guide exchanger is not justified unless the track access Air is made difficult by the surgical procedure (grade E). Question 7 What education and training what? All practitioners who may perform intubation should be trained in technical recommended algorithms supported (grade E). Training by simple companionship should not start on the patient. The training must include a learning model and then learning about patient (grade E). The maintenance of knowledge may involve training mannequin. Teaching techniques such as the use of LMA or intubation with a ILMA can be in the operating room after learning model (grade E). Other techniques such as oxygenation transtracheal endoscopy and clinical indications were limited. It can be done involve collaboration with other specialists such as pulmonologists and ENT (grade E). IN CONCLUSION The conference of experts answers most of the problems and situations that may arise in daily practice. It is nevertheless certain situations where clinical judgment must prevail and where the choice of strategy management is in terms of risk / benefit. The evolution of technology has simplified the management of ID. The development of algorithms a team is the cornerstone of care provided techniques are known all achievable at any time. Support an ID through the development of a strategy beforehand. Experts Conference - Sfar – 2006 ANNEXES Algorithms difficult intubation planned (1 general "umbrella" algorithm intubation and that of the oxygen). Experts Conference - Sfar – 2006 Algorithm unanticipated difficult intubation Experts Conference - Sfar – 2006 Chariots d’intubation Recommended composition of a difficult intubation trolley anesthesia or resuscitation • Magill forceps • Probes for intubation of different sizes • Macintosh blades metal of all sizes • Chucks long legs • LMA-Fastrach different sizes • A first tracheal direct: set cricothyroidotomy • Transtracheal oxygenation device enabled (manual injector) • Guide exchanger hollow extubation • Fiberscope • Mask adapted (type Fibroxy) and cannulae aid fiberoptic • For the fiberscope, it may be available on a trolley individualized difficult intubation trolley where will the light source, and all the fiberscope accessories necessary for the realization of endoscopy (the location of the carriage shall be known to all). Pediatric features: available material must be adapted to the size and weight of children in care. • Straight blades Miller • LMA-Fastrach size 3 for children over 30 kg • Laryngeal masks of different sizes for children less than 30 kg Composition of a truck or in case of difficult intubation Emergency Medicine • Magill forceps • Probes of different sizes • Macintosh blades metal of all sizes • Chucks long legs • LMA-Fastrach • Set cricothyroidotomy Layout and printing: Bialec, Nancy (France) - Legal Deposit No. 66888 - April 2007