Unit 1- Chapter 5- Human Genomics- CfE Higher Human Biology
Medical and Forensic Fields. To test for conditions like cystic fibrosis and identify crime suspects and a potential father in a paternity dispute
I am the term used to describe the study of the human genome where the sequence of bases along the DNA is determined
Pharmacogenetics
I am the name of the drug used to thin blood that varies in its effect on different people
Genetic Discrimination
I am the possible advantages of personal genomic sequencing being used widely in the future
Bioinformatics
I am the types of gene sequences that can be searched for using bioinformatics
Around 2200
I am the factors that most medical disorders depend on for their expression
‘Out-of-Africa’ Theory
I am the name given to the complete sequencing of a person’s DNA bases
Personal Genome Sequence
I am the term used to describe altered genetic sequences that have no negative effect
Genetic and Environmental Factors
I am the study of the effects(therapeutic, neutral or adverse) of pharmaceutical drugs on the genetically diverse members of the human population
Africa
I am the theory that proposes that humans originated in Africa and underwent early evolutionary divergence in that continent over a very long period of time (e.g. millions of years) to form genetically different populations.
Small groups then migrated out of Africa to give rise to all other human populations.
Neutral
I am the number of genetic disorders and diseases in humans for which a causal link between the disorder and a particular mutant variant in a genomic sequence has been identified.
Human Genomics
I am the name given to the fusion of molecular biology, statistical analysis and computer technology
Be able to assess predisposition to a disease, predict risk and reduce risk through a combination of drug treatment and lifestyle changes
I am the technique used to create many copies of a piece of DNA in vitro

Four Identical Molecules of DNA
I am the orderly arrangement of thousands of different DNA probes as tiny spots attached to a glass slide
Protein-Coding Sequences, Start Sequences and
Stop Codons
I am the study of a group of living things with respect to their diversity, relatedness and classification
Side Effects
I am the problems that could people could face if personal genomic sequencing becomes routine and widely available
Polymerase Chain Reaction (PCR)
I am the process that PCR depends on whereby the SNA is heated
Thermal Cycling
I am the enzymes obtained from a bacterium native to hot springs that adds nucleotides to the primers at the 3’ end of the original DNA strands.
Systematics
I am the continent on which there is the greatest variation amongst the human population compared to other continents
Single Nucleotide Polymorphism(SNP)
I am the two fields that PCR can be used in
DNA Probe
I am the type of labelling used with a DNA probe
Warfarin
I am what would be reduced ideally if personal genomic sequencing is used to customise medical treatment to suit an individual’s needs as opposed to using a ‘one-size-fits-all approach to treatment
Heat-Tolerant DNA Polymerase
I am the number of identical molecules of DNA that will be produced by the second cycle of
PCR, if by the end of the first cycle there are two identical molecules of DNA
DNA Microarray
I am a short, single-stranded fragment of DNA used to detect the presence of a specific sequence of nucleotide bases in a sample of
DNA
Fluorescent Labelling
I am the variation in DNA sequence that affects a single base pair in a DNA chain