SUPPLEMENTARY TABLE: Clinical Classification Software (CCS) Groups Included in Diagnosis and Procedure Categories CCS Diagnosis Group 11 Description Cancer of head and neck Diagnosis Category: Malignancy CCS Diagnosis Description Group 22 Melanomas of skin Other non-epithelial cancer of 23 skin CCS Diagnosis Group 33 Cancer of kidney and renal pelvis 12 Cancer of esophagus 13 Cancer of stomach 24 Cancer of breast 35 14 15 Cancer of colon Cancer of rectum and anus Cancer of liver and intrahepatic bile duct 25 26 Cancer of uterus Cancer of cervix 36 37 Cancer of brain and nervous system Cancer of thyroid Hodgkin`s disease 27 Cancer of ovary 38 Non-Hodgkin`s lymphoma 17 Cancer of pancreas 28 Cancer of other female genital organs 39 Leukemias 18 Cancer of other GI organs; peritoneum 29 Cancer of prostate 40 Multiple myeloma 19 Cancer of bronchus; lung 30 Cancer of testis 41 Cancer; other and unspecified primary 31 Cancer of other male genital organs 42 Secondary malignancies 32 Cancer of bladder 43 Malignant neoplasm without specification of site 16 20 21 Cancer; other respiratory and intrathoracic Cancer of bone and connective tissue Diagnosis Category: Chemotherapy CCS Diagnosis Group 45 Description Maintenance Chemotherapy 34 Description Cancer of other urinary organs Diagnosis Category: Infection CCS Diagnosis Group 1 Description Tuberculosis CCS Diagnosis Group 90 Description Inflammation, infection of eye Otitis media and related conditions Peri, endo, and myocarditis, cardiomyopathy CCS Diagnosis Group 147 2 Septicemia (except in labor) 92 3 Bacterial infection, unspecified site 97 4 Mycoses 122 Pneumonia 197 6 Hepatitis 123 Influenza 201 7 Viral infection 125 Acute bronchitis 237 8 76 77 78 CCS Diagnosis Group 49 50 51 Other infections; including parasitic Meningitis Encephalitis Other CNS infection and poliomyelitis Description Diabetes mellitus without Complications Diabetes mellitus with complications Other endocrine deficiencies Anal and rectal conditions 148 Peritonitis and intestinal abscess 159 Urinary tract infections 133 134 Other upper respiratory infections Other lower respiratory disease Other upper respiratory disease 135 Intestinal infection 249 Diagnosis Category: Non-Infectious Toxicities CCS Diagnosis Description Group CCS Diagnosis Group 126 Description Skin and subcutaneous tissue infections Infective arthritis and osteomyelitis Complications of device, implant or graft 246 Fever of unknown origin 247 248 Lymphadenitis Gangrene Shock Description 102 Nonspecific chest pain 152 Pancreatic disorders (not diabetes) 103 Pulmonary heart disease 153 Gastrointestinal hemorrhage 108 Congestive heart failure; 155 Other gastrointestinal disorders nonhypertensive 207 Acute and unspecified renal failure Other diseases of bladder and urethra Genitourinary symptoms and illdefined conditions Pathologic fracture 211 Other connective tissue disease 52 Nutritional deficiencies 109 Acute cerebrovascular disease 157 55 Fluid and electrolyte disorders 117 Other circulatory disease 162 59^ Deficiency and other anemia 118 60^ Acute post-hemorrhagic anemia Coagulation and hemorrhagic disorders 129 63^ Diseases of white blood cells 131 64^ Other hematologic conditions 137 Diseases of mouth 238 81 Other hereditary and degenerative nervous system conditions 138 Disorders of esophagus 242 83 Epilepsy; convulsions 139 Gastroduodenal ulcer 244 84 Headache; including migraine 140 250 95 Other nervous system disorders 141 251 Abdominal pain 98 Essential hypertension 145 Gastritis and duodenitis Other disorders of stomach and duodenum Intestinal obstruction without hernia Other injuries and conditions due to external causes Nausea and vomiting 252 Malaise and fatigue 99 Hypertension with complications and secondary hypertension 151 Other liver diseases 253 Allergic reactions 62^ 130 Phlebitis; thrombophlebitis and thromboembolism Aspiration pneumonitis Pleurisy, pneumothorax, pulmonary collapse Respiratory failure, insufficiency, arrest Procedure Category Chemotherapy CCS Procedure Group 224 Description Cancer Chemotherapy 163 212 Other bone disease and musculoskeletal deformities Complications of surgical procedures or medical care Poisoning by other medications and drugs CCS Procedure Group Description Procedure Category: Cancer-Related CCS Procedure Description Group Tracheoscopy and laryngoscopy 35 with biopsy CCS Procedure Group Description 99 Other OR GI Therapeutic procedures Lobectomy or pneumonectomy 100 Endoscopy and endoscopic biopsy of the urinary tract 37 Diagnostic bronchoscopy and biopsy of bronchus 101 Transuretheral excision, drainage, or removal urinary obstruction Diagnostic Spinal tap 38 Other diagnostic procedures on lung and bronchus 103 Nephrotomy and nephrostomy 5 Insertion of catheter or spinal stimulator and injection into spinal canal 39 Incision of pleura, thoracentesis, chest drainage 104 Nephrectomy, partial or complete 7 Other diagnostic nervous system procedures 40 109 Procedures on the urethra 9 Other OR therapeutic nervous system procedures 42 110 Other diagnostic procedures of urinary tract 10 Thyroidectomy, partial or complete 47 112 Other OR therapeutic procedures of urinary tract 11 Diagnostic endocrine procedures 54 114 Open prostatectomy 1 Incision and Excision of CNS 2 Insertion, replacement, or removal of extra-cranial ventricular shunt 36 3 Laminectomy, excision intervertebral disc 4 12 15 Other therapeutic endocrine procedures Lens and cataract procedures Other diagnostic procedures of respiratory tract and mediastinum Other OR Rx procedures on respiratory system and mediastinum Diagnostic cardiac catheterization, coronary arteriography Other vascular catheterization, not heart 65 Bone marrow biopsy 116 66 Procedures on spleen 118 Diagnostic procedures, male genital Other OR therapeutic 16 17 18 Repair of retinal tear, detachment Destruction of lesion of retina and choroid Diagnostic procedures on eye 67 71 Other therapeutic procedures, heme and lymphatic system Gastrostomy, temporary and permanent Colostomy, temporary and permanent Ileostomy and other enterostomy 119 120 74 Gastrectomy 130 75 Small bowel resection 132 78 Colorectal resection Local excision of large intestine lesion 142 157 Amputation of lower extremity 124 22 24 Mastoidectomy 80 25 Diagnostic procedures on ear 83 Biopsy of liver 159 26 Other therapeutic ear procedures 87 Laparoscopy 161 27 Control of epistaxis 89 Exploratory laparotomy 162 Plastic procedures on nose 90 Excision, lysis peritoneal adhesions 164 20 21 28 30 31 33 Tonsillectomy and/or adenoidectomy Diagnostic procedures on nose, mouth and pharynx Other OR therapeutic procedures on nose mouth and Other operations on ovary Hysterectomy, abdominal or vaginal Other excision of cervix and uterus Other diagnostic procedures, female organs Other OR therapeutic procedures, female organs Partial excision of bone 72 Other therapeutic procedures on eyelids, conjunctiva cornea Other intraocular therapeutic procedures Other extraocular muscle and orbit therapeutic procedures Tympanoplasty 19 procedures, male genital Oophorectomy, unilateral and bilateral 73 92 94 96 Other bowel diagnostic procedures Other OR upper GI therapeutic procedures Other OR lower GI therapeutic procedures 125 165 166 167 Other procedures on musculoskeletal system Other OR therapeutic procedures on bone Other OR therapeutic procedures on joints Other OR therapeutic procedures on musculoskeletal system Breast biopsy and other diagnostic procedures on breast Lupectomy, quadrantectomy of breast Mastectomy 34 pharynx Tracheostomy, temporary or permanent ^ CCS Groups included cytopenia diagnoses 97 Other GI diagnostic procedures 174 Other non-OR therapeutic procedures on skin and breast