Name: _________________________ PRACTICE TEST – Unit 7: Environmental Health and Toxicology AP Environmental Science – February 11, 2014 Directions: Choose the letter of the best answer and darken its bubble. 1. Information gathered by a scientist about the toxicity of chemical X and chemical Y showed that they had individual safe limits for fish at particular concentrations. But when they were used together at the safe concentrations, there were extensive fish kills. This is an example of (A) homeostasis (B) synergism (C) commensalism (D) bioaccumulation (E) antagonism 2. The major source of radon in houses in the United States is (A) (B) (C) (D) (E) furniture and carpets the underlying bedrock the atmosphere nuclear power plants fossil fuel combustion 3. The major human health problem related to radon accumulation is (A) lung cancer (B) heart disease (C) pancreatic cancer (D) cataracts (E) malignant melanoma 4. For a certain insecticide, the LD-50 dosage level for rats is determined to be 250 milligrams per kilogram of body mass. On the basis of this information, which of the following is the best prediction regarding the consequences of receiving this dosage of the insecticide? (A) Fifty percent of any rat population would be sickened. (B) Fifty percent of the population of any warm-blooded animal would die. (C) Fifty percent of any population of mosquitoes would die. (D) Five hundred out of every one thousand people would experience acute effects. (E) Five hundred out of every one thousand rats would die. 5. Liver disease that develops due to long-time use of alcohol and drugs would be an example of: (A) chronic effect (B) synergistic effect (C) acute effect (D) additive effect (E) cumulative effect 6. Funding research to improve treatment of which of the following infectious diseases would decrease global death rates the most? (A) Avian flu (B) Influenza (C) HIV (D) Malaria (E) SARS 7. Which of the following are characteristics of methyl mercury? I. Fat soluble II. It biomagnifies in food chain III. Low persistence in aquatic systems (A) I only (B) II only (C) III only (D) I and II only (E) I and III only 8. This is caused by the biomagnification of mercury in fish. (A) Minimata disease (B) Eutrophication (C) Kwashiorkor (D) Sediment (E) Calcium ions 9. Which of the following types of toxic compounds is most often responsible for causing the growth of cancerous cells? (A) Teratogen (B) Mutagen (C) Irritant (D) Allergen (E) Oxidation agent 10. Farmers in the Midwest United States have discovered that the local frog population is declining. Scientists determine this is due to male frogs’ inability to produce sperm. Which of the following is the likely cause? (A) Exposure to arsenic from local metal smelting plants. (B) Inhalation of inorganic mercury from local power plant emissions. (C) High levels of atrazine in the water from agricultural runoff. (D) Absorption of high levels of nitric acid through their skin. (E) Increasing UV radiation in the Midwest 11. Ecologists have been studying populations in tropical regions to determine the effects of DDT on aquatic systems. Which population would you expect to show the most effects? (A) Phytoplankton (B) Small benthic fish (C) Zooplankton (D) Larger schooling fish like tuna (E) Predatory birds like pelicans 12. Which of the following consumer products would most likely increase your exposure to bisphenol A? (A) Wood paneling in the home (B) Imported fruit from tropical regions (C) Plastic food containers and water bottles (D) Perfumes and hairsprays (E) Oil-based paints 13. All of the following are reasons why tuberculosis (TB) is still a growing threat in developing countries EXCEPT: (A) It spreads rapidly from person to person. (B) There are very few screening and control programs. (C) Strains of TB bacteria have developed antibiotic resistance. (D) People living in crowded conditions increases the spread of the disease. (E) There are no effective drugs currently offered to treat TB. 14. Which statement best illustrates limitations to determining the toxicities of environmental chemicals? (A) Humans are not exposed to just one chemical; they are exposed to a mixture of chemicals that may produce synergistic effects. (B) It is too expensive to test toxins that could be harmful to humans. (C) The wide genetic variability of humans limits scientists’ ability to determine toxicity trends for environmental chemicals. (D) Recent legislation has limited the amount of animal testing that can take place. (E) It is difficult to determine what types of chemicals humans are exposed to. 16. Which of the following is a likely reason why the United States could ban DDT without seeing an increase in malaria cases? (A) Since the United States is a developed nation there is adequate access to healthcare to prevent the disease. (B) Most children in the United States are vaccinated against malaria. (C) The United States does not typically have the genus of mosquito that carries the Plasmodium parasite. (D) The United States replaced DDT with another effective pesticide that keeps mosquito populations down. (E) People in developed nations have adequate access to bug spray preventatives. 17. Scientists determined that the LD-50 for a particular chemical toxin was a dosage level of 125 milligrams per kilogram of body mass for a test population of rats. Assuming that the toxic effect observed in rats is the same for similar animals of larger size, what dosage level would be needed to kill 50% of the population of mammals who typically have a mas of 20kg? (A) 2.5 g (B) 25 g (C) 250g (D) 2,500g (E) 25,000g 18. An organic chemical compound that is a known carcinogen and commonly found in tobacco smoke is (A) vinyl chloride (B) phthalate (C) mercury (D) radon (E) benzene 15. Which of the following is an example of a nontransmissible disease that is a leading killer worldwide and in the United States? (A) Asthma (B) Liver disease (C) HIV (D) Cardiovascular disease (E) Genetic disorders 19. Above is a dose-response curve for a toxic chemical. What might be the units of the x and y axes, respectively, and what might be calculated from the chart? (A) Number of organisms; time; population growth (B) Number of organisms; concentration; strength of toxin (C) Dose; percent of organisms dead; safety range of drug or toxin (D) Concentration; number of organisms dead; LD50 (E) Dose; population size; disease frequency 20. The greatest factor that contributes to whether or not a toxicant will magnify in the environment is (A) solubility (B) persistence (C) both solubility and persistence (D) neither solubility nor persistence (E) persistence and some other variable 27. The global incidence of infectious diseases is higher (A) in developed countries compared to developing nations. (B) in warmer climates compared to cooler climates. (C) in middle aged adults compared to children or the elderly. (D) than for non-transmissible diseases. (E) in urban areas than in rural areas. 21. Which of the following is NOT a pathogen? (A) Botulism bacteria (B) Cold virus (C) Malaria mosquito (D) Athlete’s foot fungus (E) Protist that causes giardia, an intestinal disorder 22. When arctic caribou begin to retain industrial toxins in their fat cells, the toxins probably reached the caribou because of (A) plate tectonics (B) local industries (C) global distillation (D) vulcanism (E) radiation 23. This environmental crisis involved the release of toxic methyl isocyante gas in a densely populated area. (A) Love Canal (B) Bhopal Crisis (C) Exxon Valdez (D) DDT (E) Chenobyl 24. Toxicants which have the potential to interfere with the endocrine system are called (A) neurotoxins (B) mutagens (C) hormonally-active agents (D) teratogens (E) allergens 25. Which of the following is NOT caused by a waterborne pathogen? (A) Schistosomiasis (B) River blindness (C) Cholera (D) Malaria (E) Giardia 26. Which of the following is an example of a physical hazard? (A) UV radiation (B) coronavirus (C) cigarette smoking (D) asbestos (E) malnutrition 28. Asbestos is a tiny mineral that forms long, thin microscope fibers that are most often associated with damage to which organ? (A) lungs (B) muscles (C) brain (D) skin (E) liver 29. Researchers report that the threshold dose of a particular chemical for humans is 1 ppm. This means that (A) ingesting a dose higher than 1 ppm will likely result in death. (B) this chemical is effectively harmless. (C) adverse effects from this chemical only occur at doses above 1 ppm. (D) half of the population will be harmed by a dose that greater than 1 ppm. (E) natural environmental levels of this chemical typically do not exceed 1 ppm. 30. Which of the following would likely increase the risk of toxic effects from a chemical substance? I. increasing the concentration of the chemical II. increasing the frequency of contact with the chemical III. increasing the duration of contact with the chemical (A) I only (B) II only (C) I and III only (D) I and II only (E) I, II, and III 31. Which of the following pieces of legislation provides the EPA with the authority to assess the risks from various pesticides and place regulations on their use? (A) Food, Drug, and Cosmetic Act of 1938 (B) Federal Insecticide, Fungicide, and Rodenticide Act of 1947 (C) Toxic Substances Control Act of 1976 (D) Clean Air Act of 1970 (E) Clean Water Act of 1970 32. Which of the following might be the best example of synergistic effects of toxins? (A) the roles of nitrate, atrazine and DDT in reproductive abnormalities of Lake Apopka alligators (B) pesticide drift and bioaccumulation (C) acute vs. chronic exposure of various pollutants (D) U and inverted U curves and their interaction with the threshold dose (E) Minamata disease at Chernobyl 33. Malaria is an example of (A) (B) (C) (D) (E) a physical hazard a biological hazard a chemical hazard a cultural hazard an ecological hazard 34. Methylmercury was the culprit in Minamata disease. Which form of toxin is methylmercury? (A) (B) (C) (D) (E) carcinogen halogen neurotoxin pathogen parasite 35. Fetal alcohol syndrome develops when mothers drink alcohol during pregnancy. Which statement explains the reason for dramatic effect on the health of the fetus and minimal or minor effect on the health of the mother? (A) The mother’s diet of red meat causes this problem in the fetus. (B) Alcoholism is a transmissible disease that affects the fetus. (C) The smaller, quickly developing fetus is much more susceptible to the dose of alcohol than the mother. (D) Other potentially fatal conditions in the fetus cause this syndrome. (E) Only the father’s alcohol consumption affects the fetus, not the mother. 36. The US allows _________harmful chemicals into the consumer marketplace compared to many European countries, due to their regulative approach of ____________, which relies on__________________ . (A) fewer, “wait and see”, rigorous EPA/FDA testing (B) fewer, precautionary principle, rigorous premarket (C) more, precautionary principle, extensive premarket industry self-reporting (D) more, “innocent until proven guilty”, limited to no premarket testing and then recall and rigorous testing after problems are discovered (E) similar numbers of, risk assessment, LD50 testing on all industrial compounds. 37. Which of these is NOT a member of the Stockholm Convention on POPs “dirty dozen”? (A) (B) (C) (D) (E) DDT PCBs Dioxins mercury several other pesticides 38. Pollutants produced in warmer, temperate, industrialized countries become concentrated in the bodies of polar bears and Inuit Eskimos in the arctic. This is a phenomenon which depends upon which of the following? (A) higher atmospheric evaporation rates in the temperate regions. (B) higher atmospheric deposition rates in the arctic regions. (C) atmospheric and oceanic currents transport chemicals to the arctic. (D) bioaccumulation and biomagnification concentrate the chemicals in organisms at the top of the food chain. (E) all of the above contribute to the phenomenon of global distillation. 39. Select the reason for the toxicity of dioxin. (A) (B) (C) (D) It is easily biodegradable. It is persistent in the environment. The LD50 is set at 100mg/kg The daily dose is eliminated by the excretory system. (E) It causes thin egg shells in birds and reptiles. 40. An earthquake is an example of (A) a physical hazard. (B) a biological hazard. (C) a chemical hazard. (D) a cultural hazard. (E) an ecological hazard. 41. Which of the following agents is a pathogen? (A) (B) (C) (D) (E) PBDEs DDT POPs Flavivirus mosquitoes 42. Identifying the real or potential hazard, and determining its probability and severity of impact are part of (A) (B) (C) (D) (E) LD50 risk assessment toxicology bioaccumulation threshold level of toxicity 43. Which of the following statements explains why someone who eats healthy food and does not smoke may still develop lung cancer? (A) Cancer only develops in older men after they retire. (B) Some people are genetically predisposed to lung cancer. (C) The threshold level of toxicity is not reached until one abandons a healthy diet. (D) Lung cancer occurs in predominately active, healthy individuals. (E) Lung cancer results from infection following a hospital stay. 44. Select the reason that best explains why Guinea worm disease is not a problem in developed countries. (A) The main health risk in developed countries is from chronic illnesses of old age. (B) The LD50 of Guinea worm disease is higher in developed countries. (C) People have access to high quality health care to treat this disease in developed countries. (D) The water supply in developed countries is not contaminated by the vector of this disease. (E) Citizens of developed countries are routinely vaccinated against Guinea worm infection. 45. Select the infection that has resulted from resistance to standard antibiotics. (A) (B) (C) (D) (E) MRSA flu HIV Cholera yellow fever 46. One human health consequence of rising global temperatures is (A) Mountain regions may be inundated with increased infections. (B) Diseases spread by vectors will become less common. (C) HIV will become resistant to traditional therapy. (D) Influenza outbreaks may follow airline traffic. (E) Tropical diseases will spread into new areas. ANSWER KEY 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. B B A E A B D A B C E C E A D C A E C C C C B C D A B A C E B A B C C D D E B A 41. 42. 43. 44. 45. 46. D B B D A E