APBIOLOGY CH 15 Focus Questions: Chromosome Inheritance NAME: PERIOD: 1. What is the chromosomal theory of inheritance and how was it formed? 2. Compare and chromosome with a gene. 3. Why is Drosophila melanogaster a good experimental organism for genetics studies? 4. What is a linked gene? Why doe linked genes tend to be inherited together? 5. Compare and contrast parental and recombinant phenotypes. 6. Explain how crossing over can unlink genes. 7. Describe a linkage map? What is a map unit? 8. How is sex determined in humans? 9. Compare and contrast linked genes and sex- linked genes. 10. Describe the process of x-inactivation in female mammals. Explain how this phenomenon produces the tortoise shell coloration in cats. 11. Explain how nondisjunction can lead to aneuploidy 12. Describe trisomy, triploidy and polyploidy. How do these chromosomal changes occur and what are some possible consequences. 13. Distinguish between deletions, duplications, inversions and translocations. 14. What causes Down’s syndrome? 15.Explain genomic imprinting. 16. Explain why extranuclear genes are not inherited in a Mendelian fashion. APBIOLOGY CH 15 Focus Questions: Chromosome Inheritance NAME: PERIOD: 1. What is the chromosomal theory of inheritance and how was it formed? 2. Compare and chromosome with a gene. 3. Why is Drosophila melanogaster a good experimental organism for genetics studies? 4. What is a linked gene? Why doe linked genes tend to be inherited together? 5. Compare and contrast parental and recombinant phenotypes. 6. Explain how crossing over can unlink genes. 7. Describe a linkage map? What is a map unit? 8. How is sex determined in humans? 9. Compare and contrast linked genes and sex- linked genes. 10. Describe the process of x-inactivation in female mammals. Explain how this phenomenon produces the tortoise shell coloration in cats. 11. Explain how nondisjunction can lead to aneuploidy 12. Describe trisomy, triploidy and polyploidy. How do these chromosomal changes occur and what are some possible consequences. 13. Distinguish between deletions, duplications, inversions and translocations. 14. What causes Down’s syndrome? 15.Explain genomic imprinting. 16. Explain why extranuclear genes are not inherited in a Mendelian fashion.