Center for Stem Cell & Regenerative Medicine

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Computer Science Postdoctoral Fellow (Dr. Wa Xian Lab)
Job Description
Dr. Xian is seeking a Postdoctoral Research Fellow with the passion and talent for
establishing a bioinformatics framework for a new program of adult stem cells aimed at
tackling some of the most devastating and unsolved inflammatory and proliferative diseases.
In particular, the stem cell program is targeting airway inflammation including asthma and
COPD, inflammatory bowel diseases, and highly metastatic epithelial cancers of the upper GI
tract, bladder, and ovary using novel stem cell models enabled by technology developed by
Xian and colleagues (e.g. Wang et al., 2015, Nature, 522, 173-178 and Zuo et al., 2015 Nature
517, 616-620). These advances in stem cell cloning technology are yielding remarkably
instructive, patient-specific models of human diseases, robust approaches to regenerative
medicine, and novel approaches to cancer stem cells and the vexing problem of
chemotherapy resistance in cancer treatments and thus unique opportunities for
bioinformatics specialists seeking to fundamentally alter the outcome of these diseases.
The successful candidate will have an in-depth knowledge and experience in High
Throughput Sequence (HTS) data analysis (DNA Seq, mRNA Seq, ChIP Seq, micro RNA Seq,
etc.), microarray data analysis, experimental design, data integration, algorithm
development, development of sequence analysis tools (bioinformatics programming),
evaluation of analytical tools and technology, and interfacing with biologist collaborators.
The candidate is expected to be highly flexible, adaptable, and a proactive contributor. The
candidate will have the opportunity to present the collaborative results at conferences and
workshops, and in leading journals.
The ideal candidate with a proven track record of “omics” data analysis, independent
collaborative work and leading contributions to a biomedical project.
Responsibilities
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Candidate carries out Computational analysis of “omics” data, algorithm
implementation as well as bioinformatics programming. Evaluate data for quality
assurance and mining bioinformatics databases. Present results at conferences and
workshops and contribute to publication of manuscripts.
Effective project and information management to meet scientific requirements
Required Skills
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PhD in Bioinformatics, Computer Science, Biostatistics or any relevant area.
Successful incumbents will demonstrate excellent communication skills.
Prior successes in and desire to contribute to team projects on an ongoing basis is a
must.
Successful track record of working independently.
Candidates meeting the above requirement should apply by email (Wa.Xian@uth.tmc.edu) to
Wa.Xian@uth.tmc.edu, Ph.D., Institute of Molecular Medicine, Center for Stem Cell and
Regenerative Medicine, University of Texas Medical School in Houston, TX, 77030. Please
include a cover letter briefly describing research interest and future goals, detailed CV, and
1-2 references. Also state “Application for position in Computer Science” in subject area of
the email.
UTHealth is and EEO/AA employer. UTHealth does not discriminate on the basis of
race, color, religion, gender, sexual orientation, national origin, genetics, disability,
age, or any other basis prohibited by law. EOE/M/D/F/V.
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