Pathology - Q Centre

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Bin Yang, MD, PhD, is the lecture of Pathology and Laboratory Medicine of the Hospital.
He is the Medical Director of Molecular Cytopathology and Director of Cancer Epigenetics
Core Laboratory in the Department of Anatomic Pathology. Dr. Yang is clinically specialized
in gynecologic pathology and diagnostic cytopathology including fine needle aspiration
service.
Bin Yang received his M.D. in Zhengzhou University School of Medicine in China in 1983,
his Ph.D. training in Molecular Biology under supervision of Dr. Sanford Markowitz, an
investigator at the Howard Houghes Medical Institutions at the Case Western Reserve
University in 1996. He finished his pathology residency training in 2000 at the Cleveland
Clinic, his surgical pathology fellowship training in 2001 at the Washington University in St.
Louis, and his cytopathology fellowship and molecular pathology training in 2003 at the
Johns Hopkins Medical Institutions in Baltimore.
Overview
Advances in molecular and cell biology have provided us with an understanding of the
mechanisms of disease at the molecular and genetic levels. This understanding can now be
translated into diagnostic, prognostic, and therapeutic applications in modern medicine.
Abnormal molecules not only provide a signature for the presence of a disease, but may also
provide the indication for a drug targeting the specific abnormal function. Concurrently, the
role of diagnostic pathology has expanded from mere morphologic observation into
comprehensive tissue analysis through combined histological, immunohistochemical and
molecular evaluations. Yale Pathology’s program in Molecular Diagnostics is constantly
translating new discoveries and novel technologies into useful clinical tests that provide a
molecular fingerprint of diseases and that are predictive of the response. The Office of the
Chief Medical Examiner offers a fully accredited one-year training program in forensic
pathology for those who have completed anatomic and clinical pathology or anatomic
pathology training.
Residents are provided a mandatory Three-year core program in the basic principals of
anatomic and clinical pathology. Rotations also include hematopathology, neuropathology
and molecular diagnostics. Individuals with an interest in academic pathology will be
encouraged to begin their research activities in the second and/or third year of training.
Third year residents are provided sample opportunity for elective time in order to encourage
individual subspecialty interests. The residency requirements are adapted to meet the
educational and career objectives of each resident, while meeting the requirements of the
Chineese Board of Pathology . Senior training (yr. 3) includes rotations at the Medical
Examiner, Electron Microscopy and in Cytogenetics in the Department of Pathology.
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