Blood Notes 12.1 Introduction What are the 3 main functions of blood? What forms the cardiovascular system? What type of tissue is blood? (Remember there are epithelial, connective, muscular, and nervous tissues) What do red blood cells do? What do white blood cells do? What do platelets do? What is plasma? What is found within the plasma? What is hematocrit mean? What factors affect blood volume? What is the blood volume of an average-size adult? Do males and females differ in blood volume? How so? Draw a typical centrifuged blood sample. Label the layers and their percents by volume. 12.2 Blood Cells What is the name of a red blood cell? Draw a red blood cell and describe why it is shaped this way. What’s the function of hemoglobin? How does a red blood cell change as it matures? Why are red blood cell counts considered in routine health tests? How does the formation of RBCs change over time? The production of RBCs is called… How is RBC production controlled? Why are vitamins necessary for RBC development? Which vitamins are most important? Why is iron necessary for RBCs? What is anemia? What are some symptoms of anemia? How can anemia be treated? What is hemochromatosis? And how is it treated? What is sickle cell anemia and what causes it? What are the symptoms of sickle cell anemia? How can sickle cell anemia be treated? All blood cells originate from what cell type in the bone marrow? This is called a lineage of blood cells. What happens to damaged RBCs? Give details. What are the products of hemoglobin breakdown? What happens to the iron after it is released? What happens to the biliverdin? What is physiologic jaundice? What is the cause? How can this type of jaundice be treated? White blood cells are called… Where do WBCs develop? What are the 2 hormones that stimulate WBC development? How do the 5 main types of circulating WBCs differ? What are granulocytes? What are the cells in this group? What are agranulocytes? What are the cells in this group? Differentiate between the characteristics of granulocytes and agranulocytes. List the 5 WBCs How do WBCs fight infection? How do WBCs reach microorganisms outside of blood vessels? Compare and contrast neutrophils and monocytes. How can eosinophils influence allergic reactions? What chemicals do basophils contain? What do each of these chemicals do? What is the specific job of lymphocytes? What is the normal human WBC count? A change in WBC count can mean… Distinguish between leukocytosis and leucopenia. What can each tell you? What is a differential white blood cell count (DIFF) and what can it tell you? How do platelets form? How are platelets different than RBCs? What is the function of platelets?