NANO @ IOWA News from the Nanoscience and Nanotechnology Institute at UI February 4, 2015 Items in red are new this issue. (Others are carried forward from previous issues.) 1. Upcoming conferences and seminars including nanoscience and nanotechnology: What Do We Really Know about Nanoparticle Stability? Professor Amanda Haes, Department of Chemistry, University of Iowa C29 Pomerantz Center, The University of Iowa Thursday February 5, 2015 12.30-1.20pm Nanomaterials for Applications in Energy Technology: Energy Conversion, Storage, and Transport Ventura, CA February 22-27, 2015 http://www.grc.org/programs.aspx?id=15821 SUN-SNO-GUIDENANO Sustainable Nanotechnology Conference Venice, Italy March 9-11, 2015 http://www.susnano.org/conferenceOverview2015SNO-SUN-GN.html U.S.-EU: Bridging nanoEHS Research Efforts Joint Workshop Venice, Italy March 12-13, 2015 http://us-eu.org/Calendar/eu-u-s-bridging-nanoehs-research-efforts-joint-workshop/ Society of Toxicology 54th Annual Meeting San Diego, CA March 22-26, 2014 http://www.toxicology.org/AI/MEET/AM2015/ Nanoscience and Nanotechnology Institute Spring Symposium Chemistry Building, The University of Iowa Friday April 10, 2015 http://nanotech.uiowa.edu/events/nanoscience-and-nanotechnology-symposium SENN 2015 – International Congress on Safety of Engineered Nanoparticles and Nanotechnologies Helsinki, Finland April 12-15, 2015 http://www.ttl.fi/PARTNER/SENN2015/Pages/default.aspx ASME 2015 4th Global Conference on Nanengineering for Medicine and Biology Minneapolis, MN April 19-22, 2015 http://www.asmeconferences.org/NEMB2015/ 2. Upcoming grant opportunities and funding requests in nanoscience and nanotechnology: Nanomanufacturing National Science Foundation PD 14-1788 Deadline Dates: February 1 – February 17, 2015 September 1 – September 15, 2015 http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=13347 NSF: Science of Science and Innovation Policy National Science Foundation PD 09-7626 Deadline Date: February 9, 2015 and September 9, 2015 http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=501084 Multidisciplinary Research Program of the University Research Initiative Department of Defense Office of Naval Research Department of Defense ONRFOA14-012 Deadline Date: February 23, 2015 http://www.grants.gov/view-opportunity.html?oppId=266208 Irwin Andrew Porter Foundation Grant Program Irwin Andrew Porter Foundation Internal deadline: February 26, 2015 https://research.uiowa.edu/grantTrack/preselection.php?get=uiwins&GrantID=17949&Type=2 Office of Naval Research – Research Opportunity – Select Topics in Nanoscience and Nanotechnology Office of Naval Research ONR-15-SN-0002 Deadline Date: February 26, 2015 http://www.grants.gov/custom/viewOppDetails.jsp?oppId=269741 Project on Advanced Systems and Concepts for Countering WMD (PASCC) Naval Postgraduate School NPS-BAA-14-003 Deadline Date: March 31, 2015 http://www.nps.edu/Research/workingwithnps.html Innovative Research in Cancer Nanotechnology National Institutes of Health FOA Number: PAR-14-285 Deadline Date: April 15, 2015; October 15, 2015 http://grants.nih.gov/grants/guide/pa-files/PAR-14-285.html Industry/University Cooperative Research Centers Program National Science Foundation nsf13-594 Deadline Dates: Letter of Intent June 26, 2015; Full proposal September 25, 2015 http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=5501&org=NNCO&sel_org=NNCO&from=f und Science, Technology, and Society National Science Foundation 15-506 Deadline Date: August 3, 2015 http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=5324 Army Research Laboratory BAA for Basic and Applied Scientific Research Department of Defense FOA Number: W911NF-12-R-0011 Deadline Date: March 31, 2017 http://www.arl.army.mil/www/default.cfm?page=8 Image-guided Drug Delivery in Cancer National Institutes for Health (NIH) FOA Number: PA-09-253 Deadline Dates: January 25, May 25, and September 25, annually http://grants.nih.gov/grants/guide/pa-files/PA-09-253.html Development of Multifunctional Drug and Gene Delivery Systems National Institutes for Health (NIH) FOA Number: PA-10-048 Deadline Dates: February 5, June 5, and October 5, annually http://grants.nih.gov/grants/guide/pa-files/PAR-10-048.html Nanoscience and Nanotechnology in Biology and Medicine National Institutes of Health (NIH) FOA Number: PA-11-148 Deadline Dates: February 5, June 5, October 5, annually http://grants.nih.gov/grants/guide/pa-files/PA-11-148.html Bioengineering Nanotechnology Initiative National Institutes of Health (NIH) FOA Number: PA-10-149 Deadline Dates: April 5, August 5, December 5, annually http://www.grants.gov/web/grants/view-opportunity.html?oppId=53500 Cancer Diagnostic and Therapeautic Agents Enabled by Nanotechnology National Institutes of Health (NIH) FOA Number: PAR-10-286 Deadline Dates: April 5, August 5, December 5, annually http://grants.nih.gov/grants/guide/pa-files/PAR-10-286.html 3. Recent news and updates from NNI: Spring 2015 Nanoscience and Nanotechnology Symposium Save the date! Friday April 10, 2015 all-day symposium with keynote speaker Dr Philip Demokritou, Associate Professor,Director, Laboratory for Environmental Health NanoScience (LEHNS), and Director, Center for Nanotechnology and Nanotoxicology Harvard School of Public Health who will talk on “In-vitro Dosimetry of Nanomaterials: Too complicated to consider, too important to ignore” Nano REU program accepting applications The National Science Foundation Research Experience for Undergraduates (NSF-REU) program in Nanoscience and Nanotechnology at The University of Iowa is now accepting applications. The application deadline is March 2, 2015. Please find all the details on the website: http://nanotech.uiowa.edu/education/nano-reu-program/application 4. Highlights of some new interesting nanoscience and nanotechnology research and articles: Nanoparticles for clean drinking water One way of removing harmful nitrate from drinking water is to catalyze its conversion to nitrogen. This process suffers from the drawback that it often produces ammonia. By using palladium nanoparticles as a catalyst, and by carefully controlling their size, this drawback can be eliminated. It was research conducted by Yingnan Zhao of the Univ. of Twente’s MESA+ Institute for Nanotechnology that led to this discovery. Due to the excessive use of fertilizers, our groundwater is contaminated with nitrates, which pose a problem if they enter the mains water supply. Levels have fallen significantly in recent years, as a result of various European directives. In addition, the Integrated Approach to Nitrogen program was launched in various Dutch nature reserves at the start of January. Tackling the problem at source is one thing, but it will still be necessary to treat the mains water supply. While this can be achieved through biological conversion—bacteria convert the nitrate to nitrogen gas, this is a slow process. Using palladium to catalyze the conversion of nitrate to nitrogen speeds up the process enormously. However, this reaction suffers from the drawback that it produces a harmful by-product— ammonia. http://www.rdmag.com/news/2015/01/nanoparticles-clean-drinking-water Self-Assembling Carbohydrates Trap Cancer Cells In A Cage Chemists have designed a carbohydrate-based molecule that can surround and strangle bone cancer cells by self-assembling into a tangled web of nanofibers (J. Am. Chem. Soc. 2014, DOI: 10.1021/ ja5111893). The molecule spares healthy cells because its assembly is triggered by an enzyme that’s overexpressed on cancer cells. The inspiration for spinning a molecular cage around cells came from nature, says Rein V. Ulijn of the City University of New York’s Hunter College. Many of the body’s cells are enmeshed in an extracellular matrix—a complex web of biomolecules that provides structure for tissues, facilitates intercellular communication, and traps nutrients. Scientists are developing molecules that spontaneously assemble into simpler versions of this matrix to provide a growth medium for cells, in particular for tissue engineering. The field has focused mainly on self-assembling peptides. In a recent study, Bing Xu of Brandeis University and colleagues designed a nonnurturing peptide that aggregates and engulfs cancer cells only when its phosphate group is removed (Angew. Chem. Int. Ed. 2014, DOI: 10.1002/anie.201402216). The phosphate-free peptides have a hydrophilic end and a hydrophobic one, which allow them to assemble like lipids in a cell membrane. The negative charge on the phosphate groups creates electrostatic repulsion between the molecules and prevents this. This phosphate on-off switch is great for targeting cancer because some types of cancer cells overexpress alkaline phosphatase, an enzyme that cleaves phosphates. http://cen.acs.org/articles/93/web/2015/01/Self-Assembling-Carbohydrates-Trap-Cancer.html New laser-patterning technique turns metals into supermaterials By zapping ordinary metals with femtosecond laser pulses researchers from the University of Rochester in New York have created extraordinary new surfaces that efficiently absorb light, repel water and clean themselves. The multifunctional materials could find use in durable, low maintenance solar collectors and sensors. "This is the first time that a multifunctional metal surface is created by lasers that is superhydrophobic (water repelling), self-cleaning, and highly absorptive," said Chunlei Guo, a physicist at the Institute of Optics at the University of Rochester who made the new surfaces with his colleague and fellow University of Rochester researcher Anatoliy Vorobyev. The researchers describe the laser-patterned surfaces in an article published in the Journal of Applied Physics ("Multifunctional surfaces produced by femtosecond laser pulses"). http://www.nanowerk.com/nanotechnology-news/newsid=38767.php Researchers tune friction in ionic solids at the nanoscale Friction impacts motion, hence the need to control friction forces. Currently, this is accomplished by mechanistic means or lubrication, but experiments conducted by researchers at the Department of Energy's Oak Ridge National Laboratory have uncovered a way of controlling friction on ionic surfaces at the nanoscale using electrical stimulation and ambient water vapor. The research, which demonstrates a new physical effect, was undertaken at the Center for Nanophase Materials Sciences, a DOE Office of Science User Facility at ORNL, and is published in the journal Scientific Reports. "Our finding can have a significant technological impact on applications for both macroscopic and nanoscale devices," said lead author Evgheni Strelcov. "Decreasing or increasing nanoscale friction at will and thus controlling mechanical energy losses and wear of a microelectromechanical system's parts has enormous implications for applied energy research and opens a new vista for fundamental science studies." http://phys.org/news/2015-01-tune-friction-ionic-solids-nanoscale.html About NANO @ IOWA NANO @ IOWA is a biweekly electronic newsletter to inform faculty, staff and students about important news and events in nanoscience and nanotechnology. This newsletter is provided as a service of the Nanoscience and Nanotechnology Institute at UI (NNI). To subscribe to NANO @ IOWA, please send an email to NNI@uiowa.edu with subject line: Subscribe NANO @ IOWA. In the body of the message, type: (your first name) (your last name). To unsubscribe, send an email message to: NNI@uiowa.edu with subject line: Unsubscribe NANO @ IOWA. In the body of the message, type: (your first name) (your last name). If you have news for NANO @ IOWA, please e-mail jenny-nelson@uiowa.edu or call Jenny Nelson at 319-384-3292. http://nanotech.uiowa.edu