Degree and Diploma Programs by Graduate Unit 2014-15 SGS Calendar Pharmacology and Toxicology Faculty Affiliation Medicine Degree Programs Offered Pharmacology—MSc, PhD Field: Applied Clinical Pharmacology (MSc only) Collaborative Programs The following collaborative programs are available to students in participating degree programs as listed below: 1. Addiction Studies Pharmacology, MSc, PhD 2. Biomedical Toxicology Pharmacology, MSc, PhD 3. Cardiovascular Sciences Pharmacology, MSc, PhD 4. Neuroscience Pharmacology, MSc, PhD 5. Resuscitation Sciences Pharmacology, MSc, PhD 6. Women's Health Pharmacology, MSc, PhD Overview The Department of Pharmacology and Toxicology offers graduate programs leading to the degrees of Master of Science and Doctor of Philosophy in Pharmacology. Faculty conduct research in the following areas: biochemical and molecular pharmacology cardiovascular pharmacology clinical pharmacology drug addiction drug metabolism, distribution, and pharmacokinetics endocrine pharmacology immunopharmacology neuropharmacology pharmacogenetics psychopharmacology receptor pharmacology second messengers and signal transduction toxicology All MSc and PhD students are expected to undertake selfdirected study and to demonstrate proficiency in pharmacological principles throughout the course of their graduate program. 2014-2015 School of Graduate Studies Calendar www.sgs.utoronto.ca/calendar Contact and Address Web: www.pharmtox.utoronto.ca Email: pharmtox.dept@utoronto.ca Telephone: (416) 978-5244 Fax: (416) 978-6395 Department of Pharmacology and Toxicology University of Toronto Room 4207, Medical Sciences Building Toronto, Ontario M5S 1A8 Canada Degree Programs Pharmacology Master of Science Minimum Admission Requirements Applicants are admitted under the General Regulations of the School of Graduate Studies. Applicants must also satisfy the Department of Pharmacology and Toxicology's additional admission requirements stated below. Appropriate bachelor's degree from a recognized university with a final-year average of at least a B+. Applicants are normally required to have taken courses in physiology, biochemistry, or applied sciences sufficient to form a foundation for their work in pharmacology. All successful applicants are responsible for obtaining research supervision and financial support before they are permitted to officially register in their program. Program Requirements Minimum period of one full year of residence, during which time the student is required to be on campus fulltime and consequently in such geographical proximity as to be able to participate fully in the department's activities associated with the program. PCL 1002Y Graduate Pharmacology. The academic program may require additional coursework. Each student will present a departmental seminar after approximately one year in the program. Each student will participate in a research program and present the results of the investigation as a written thesis. The thesis will be evaluated and defended to the satisfaction of a thesis examination committee. MSc students in pharmacology who intend to continue their studies in the PhD program may choose to be evaluated during their MSc oral defence. Pharmacology and Toxicology 1 Degree and Diploma Programs by Graduate Unit Field: Applied Clinical Pharmacology Major Research Project (1.0 FCE). Students will enrol in PCL 2200Y0, normally in the Summer of Year 1 or no later than the Fall of Year 2. Minimum Admission Requirements Applicants are admitted under the General Regulations of the School of Graduate Studies. Applicants must also satisfy the Department of Pharmacology and Toxicology’s additional admission requirements stated below. An appropriate bachelor’s degree from a recognized university with a final-year average of at least a B+. Applicants are normally required to have taken courses in physiology, biochemistry, or applied sciences sufficient to form a foundation for their work in pharmacology. Advanced-Standing Option At the discretion of the program director, applicants may Program Length Advanced-Standing Option be considered for advanced standing with either: o a bachelor’s degree in pharmacology or biomedical toxicology or o MD degree (undergraduate medical education) with coursework in pharmacology. Program Requirements Completion of 8.0 full-course equivalents (FCEs) as follows: Year 1 (3.5 FCEs total): o PCL1001Y Systems Pharmacology o PCL1004Y Clinical Pharmacology o PCL1402H Pharmacology and Toxicology in Drug Development o PCL1491H Clinical Pharmacology: Principles in Practice o PCL1100H Applied Skills in Clinical Pharmacology Year 2 (3.5 FCEs total): o Required courses (1.5 FCEs): PCL1002Y Graduate Pharmacology PCL1101H Technology in Pharmacology and Toxicology plus o Elective courses (2.0 FCEs) from the following list: PCL 1012H Cognitive Neuropharmacology PCL 1300H Selected Topics in Clinical Studies PCL 2100H Practicum in Clinical Pharmacology PCL 2101Y Practicum in Clinical Pharmacology BTC 1830H Medical and Scientific Challenges in Marketing New Therapeutics JFK 1120H Selected Topics in Drug Development I JNP 1014Y Interdisciplinary Toxicology JPM 1005Y Behavioural Pharmacology LMP 1407H Introductory Biostatistics and Clinical Investigation or CHL 5201H Biostatistics for Epidemiologists Clinical practicums (either PCL 2100H or PCL 2101Y; CR/NCR), if chosen from electives, must be completed by Year 2. 2014-2015 School of Graduate Studies Calendar www.sgs.utoronto.ca/calendar Completion of at least 4.0 FCEs including: PCL1002Y Graduate Pharmacology PCL1004Y Clinical Pharmacology PCL1100H Applied Skills in Clinical Pharmacology At least one half-course elective (0.5 FCE) chosen from the elective list above, and upon recommendation of the program director. PCL 2200Y0 Major Research Project, taken in the Fall of Year 1. 6 sessions full-time (typical registration sequence: F/W/S/F/W/S); 3 sessions advanced-standing (typical registration sequence: F/W/S); 9 sessions part-time Time Limit 3 years full-time; 6 years part-time 0 Course that may continue over a program. The course is graded when completed. Doctor of Philosophy Minimum Admission Requirements Applicants are admitted under the General Regulations of the School of Graduate Studies. Applicants must also satisfy the Department of Pharmacology and Toxicology's additional admission requirements stated below. Appropriate master's degree from a recognized university with an average of at least a B+ in master's degree courses. Applicants are normally required to have taken courses in physiology, biochemistry, or apllied sciences sufficient to form a foundation for their work in pharmacology. The department determines the eligibility of prospective students. The department assesses the student's ability for advanced study and independent research in pharmacology. Well-qualified students with excellent research potential holding an appropriate bachelor's degree from a recognized university may be considered for direct admission to the PhD program. These applicants must have achieved a minimum final year average of A-. Applicants admitted without prior screening (i.e., with MSc degrees from other departments or universities, and students admitted with a bachelor's degree) will have their research ability reviewed after completion of one year. Upon successful completion of a departmental Pharmacology and Toxicology 2 Degree and Diploma Programs by Graduate Unit seminar and recommendation from the student's advisory committee, the student will be permitted to proceed with the PhD program. Students transferring from the master's program in pharmacology to the PhD program may receive full credit for master's courses towards doctoral course requirements, with the department's permission. The department must be satisfied about the applicant's background, accomplishments, and financial support. All successful applicants are responsible for obtaining research supervision and financial support before they are permitted to officially register in their program. 0 Course that may continue over a program. The course is graded when completed. Course List The department should be consulted each session as to course offerings. Students may also find up-todate course information on the departmental website. PCL 1001Y Systems Pharmacology PCL 1002Y Graduate Pharmacology PCL 1003Y0 Seminars in Pharmacology (Credit/No Credit) PCL 1004Y Clinical Pharmacology PCL 1012H Cognitive Neuropharmacology PCL 1110H Applied Skills in Clinical Pharmacology PCL 1491Y Clinical Pharmacology: Principles in Practice (co-requisite: PCL 1004Y or prior pharmacokinetics course) PCL 2200Y0 Major Research Project (prerequisite or co-requisite: PCL 1100H) JFK 1120H Selected Topics in Drug Development I JFK 1121H Selected Topics in Drug Development II JFK 1122H Drug Transport Across Biological Membranes JNP 1014Y Interdisciplinary Toxicology JNP 1016H Graduate Seminar in Toxicology JNP 1017H+ Molecular and Biochemical Basis of Toxicology JNP 1018H+ Current Topics in Molecular and Biochemical Toxicology JNR 1444Y Fundamentals of Neuroscience: Cellular and Molecular JPM 1005Y Behavioural Pharmacology JYG 1555H Topics in Cellular and Molecular Neurobiology Program Requirements Minimum period of two full years of residence, during which time the student is required to be on campus fulltime and consequently in such geographical proximity as to be able to participate fully in the department's activities associated with the program. PCL 1002Y Graduate Pharmacology (major subject), PCL 1003Y0 Seminars in Pharmacology (Credit/No Credit course), 1.0 additional FCE (minor subject), and any other courses advised by the Graduate Education Committee. The student's advisory committee should help the student determine the minor course. Pharmacology graduate faculty members also offer a variety of laboratory-based and tutorial-based learning modules to provide breadth to the student's training experience beyond their particular areas of research focus. During their program, PhD students are required to choose four breadth modules from among available options. 0.5 FCE from outside the student's research area may substitute for one of the five breadth modules. The student's advisory committee will assist the student in choosing suitable modules. As part of the course requirement for PCL 1003Y Seminars in Pharmacology, the student must present thesis material in seminars to the department on two occasions, one of which will take place between two and six months prior to the departmental Final Oral Examination. Each student will participate in a research program and present the results of the investigation as a written thesis. The thesis must be orally defended to the satisfaction of a thesis examination committee. PhD students in other departments who desire to take a minor in pharmacology will be permitted to take one of the listed courses depending on their previous training and space availability in the course. Program Length 4 years full-time; 5 years direct-entry Time Limit 0 Course that may continue over a program. The course is graded when completed. + Extended course. For academic reasons, coursework is extended into session following academic session in which course is offered. 6 years full-time; 7 years direct-entry 2014-2015 School of Graduate Studies Calendar www.sgs.utoronto.ca/calendar Pharmacology and Toxicology 3