Water Quality Analysis Prioritisation The Transmission cycle of disease This study will focus on disease caused by pathogens, infectious agents, or the toxins that the produce. For a pathogen to survive it must be able to leave an infected host, survive transmission in the environment and develop or multiply in the newly infected host (DISEASE). This cycle is known as the transmission cycle of disease. Figure 1 Example Transmission Cycle The pathogens which cause disease are generally split into several categories, Food-borne, Waterborne, Vector-borne and Water-washed. For this project we will be focussing on water-borne pathogen cycles. (Water-washed are water related pathogens whose spread is reduced by improvements in hygiene and as such fall outside the major scope of our project.) The infectious dose of a pathogen is the number of pathogens that have to enter the body of a susceptible person to cause infection. This is a characteristic mainly related to faecal-oral transmission, of which many water-borne pathogens fall into. `Health is improved by breaking the transmission cycle of diseases present in the project area (DISEASE) and therefore, in order to design a system to improve health the pathogens and their infectious doses must be established. This will allow us to decide the level of water quality we should aim to treat to improve health. Analysis of Pathogens In order to establish which pathogens we wish to treat qualitative analysis has been performed to give us a relative risk scale. The process followed can be seen in (FIGURE). The research undertaken suggests that there is a health problem to be solved. This leads us to hazard identification and a risk analysis. In order to do this each pathogen was assessed and rated against the following criteria (TABLES 1, 2, 3) and a overall risk factor computed (TABLE 4). Likelihood qualitative scale: Score Exist 0 No 1 Yes Description… in terms of chance of people getting sick upon ingestion Problems and Disease not present in the area Problems confirmed in the area by local dctors Consequence (time) qualitative scale: Time, not cost, is the parameter used to quantify hardship because interviews with locals did not indicate money saving to be a priority. Consequences of pathogen ingestion will vary from person to person, given the scope and level of detail of this analysis, each consequence score is chosen so as to describe the most common scenarios we encountered in our research. Pathogen consequence score allocation will be backed up by medical articles/studies. Score Description… in terms of time lost from work for men and from school for children 1 1 day 2 Less than 1 week 3 1-4 Weeks 4 Greater than a month 5 Long term health implications Consequence (severity) qualitative scale: Pathogen strains may vary, resulting in a wide range of severity Pathogen consequence score allocation will be backed up by medical articles/studies. Severity differs from time cost since some diseases may not result in huge loss of work, but may occur over long periods of time, whilst some may occur over a short period of time, but there is a chance of fatality. Score Description… in terms of possible health consequences of disease 1 Low 2 Low, very serious on rare occasions 3 Severe 4 Severe, higher chance of fatality amongst young, elderly etc. 5 High chance of fatality if untreated Minerals In the 1980s/1990s water quality problems due to chemicals begun to emerge. This occurred as there was a switch to use of more ground water sources and also due to increased use of fertiliser and pesticide use in both agricultural and industrial use, both potential problems in this area. WATER AID. These minerals and their affects have been included TABLE 4, and rated using the same analysis as the pathogens. Disease Bacterial enteritis, Campylobacter enteritis, Diarrhoea, Gastroenteritis Bacterial enteritis (Ecoli), Diarrhoea, Gastroenteritis Bacterial enteritis, Salmonellosis, Diarrhoea, Gastroenteritis Bacterial enteritis, Yersiniosis, Diarrhoea, Gastroenteristis Bacillary dysentry, Shigellosis Cholera Viral enteritis, Viral gastroenteritis, Viral Diarrhoea, Diarrhoea Pathogen Campylobacter Jejuni, C. Coli Infectious Dose Likilihood Consequence (time) Consequence (severity) Risk Factor >500 1 2 2 5 low 1 3 4 8 v small to v high 1 2 3 6 med-high 1 3 3 7 10-100 1 2 4 7 2 5 Not Present Escherichia coli Salmonella Yersina entercolitica, Y.psuedotuberculosis Shigella Vibrio Cholera Rotavirus Dysentry (ameobic), Ameobis Entamoeba hostolytica Giardia enmteritis, Giardiasis Cryptosporidiosis Giardia lamblia Cryptosporidium parvum 10^6 - 10^8 106 - 10^4 1 2 4 7 low 1 5 1 7 10-100 4 2 Not Present low 3 1 Not Present Dysentry (Balantidial), Balantidiasis Typhoid, Enteric fever, Typhoid fever, Paratyphoid fever Weil's disease, Leptospirosis Balantidium coli Salmonella typhi, Salmonella paratyphi Leptospira low 1 5 4 10 10^3 - 10^9 3 5 Not Present low 3 2 Not Present Fluoride Digestive Disorders, Skin Diseases, Dental Flurosis, Skeletal Flurosis >1.5mg/l 1 5 3 9 >1mg/l 1 5 3 9 >100mg/l 1 5 3 9 1 5 3 9 Iron Digestive Disorders, Skin Diseases, Dental Problems, Poisonous in High Doses Methamoglobinemia, Increase risk of cancer Nitrate Weakened immunity, Abnormal multiplication of cells Pesticides Is there a Health Problem? System analysis Computation of level of risk due to each pathogen HAZARD IDENTIFICATION: LIKELIHOOD of EXPOSURE: What are the main pathogens present in the water? What is the concentration of each in local water when it reaches houses? RISK CONSEQUENCE SCALE: Is there demand/need for a solution? PRA method POPULATION VULNERABILITY: How prepared is the community to protect itself against and recover from contact with pathogen? How severe are the consequences, given contact with pathogens? n.b. hardship assessed against comm. values Determination of Adequate Level of Water Quality Establishing adequacy of design solution intervention