Крок 2 (2014) иммунология и аллергология. 1/16 A child 10 years old was diagnosed with lacunar tonsillitis, cervical lymphadenitis. On the 5th day of illness, the child has revealed an increase in liver size up to 2 cm and spleen on sm In the General analysis of blood identified: the lake . - 15,6 * 109 / l , F - 3% , P - 4% , 15 % , L - 45 % , M - 10 % , veracity - 23%. What disease can be suspected ? A * Infectious mononucleosis B Adenovirus infection C Strep infection D Diphtheria oropharynx E Angina Simanovsky - Vincent 2/ 26 The boy 6 years was introduced donor immunoglobulin in connection with a contact on viral hepatitis in the family. According to the schedule of vaccination at this time was planned revaccination against measles. The child examined by a district pediatrician and declared healthy . For some reason, the doctor - immunologist did not grant permission to vaccination : A * inefficiency of vaccination against the background entered immunoglobulin. B a Possible anaphylactic reaction to the vaccine. With a High probability of measles vaccination. D Possible development of viral hepatitis due to measles vaccination. 3/ 41 The child of 8 years recovering from a sore throat appeared on the skin of the legs and belly petajalampi pink color and temperature rose to 38 0C . The number of platelets in the blood 90,0 g / l , bleeding time of 15 minutes. What kind of disease you can think of ? A * Idiopathic thrombocytopenic purpura B Deficiency anemia C Hemorrhagic vasculitis D Acute lymphoblastic leukemia E Hemophilia 4/49 The child is 8 years of age diagnosed with mumps ". His brother , 4 years of mumps was sick and not vaccinated. Applying what measures can prevent disease mumps this child? A * Gammaglobulinemia B Antibiotikoterapiei C Chemoprophylaxis D Vaccination E pageprofile 5/ 67 Child was born from HIV - infected mothers . The General condition satisfactory. On Apgar scale - 8 points . Weight 3200, length - 50 see Prenatal , birth and postpartum prophylaxis of AIDS was conducted . How soon can be defined by ELISA HIV infection? A * 18 months B 6 months C in 3 months D in 1 month E In the first days after birth 6/ 68 The 5 - year-old child with a serious form of varicella with abundant polymorphic vesiculate - papular and hemorrhagic rash . The temperature within the 39 - 40 0C. Which of antiviral drugs should be administered in this case ? A * Acyclovir B Lamivudine C Reaferon D Arbidol E Rimantadine 7/83 The child of 20 - days-old was admitted to hospital on 3-rd day of the disease in heavy condition.Observed febrile fever , profuse polymorphic (spots, papules , vesicles )rash on the entire body , mucous membranes , almost all vesicles have hemorrhagic content . With application of which drug should begin therapy ? A * Acyclovir B prednisolone C anti-herpes vaccine D amantadine E interferon 8/94 When transfusions in 8 year old boy with hemophilia A ,suddenly have pain in the chest and lower back , shortness of breath , cold sweat. objectively :the skin is pale curves 100/min . , AD - 60/40 mm Hg Oliguria , urine brown. The attraction of this complication primary purpose is : A * prednisolone B lasix C Adrenaline D Eufillina E dipyrone 9/99 The child receiving inpatient treatment for Hodgkin's disease (Hodgkin's disease ) , increased body temperature up to 38,2 OS , appeared rich polymorphic rash (spots , papules , vesicles ) on the whole body. additionally, using any medicines is the most reasonable in this case? A * Acyclovir B prednisolone C ribavirin D Ceftriaxone E vancomycin 10/103 The girl complaints papular rash on the face , chest , abdomen . Itchy rash, disappearclicking. " Geographic tongue" . Temperature is normal. On the eve ate drink " Fanta " , chocolate sweets , fish products. Vnutrennyuyu pathology was not found . Eosinophilia . What is the diagnosis? A * Acute urticaria B Atopic dermatitis C Systemic lupus erythematosus D Thrombocytopenic purpura E Measles 11/109 Child 6 years, complains of headache , fatigue , weakness , decreased appetite, increased body temperature to 37.4-37,80 With , pain in the joints of his left hand , more at night ,gemorragii . Complaints appeared 1 month ago. In the General analysis of blood :erythrocytes-,9 g / l hemoglobin - 45 g / l , color indicator -0,77 ; ESR 70 mm / h; platelets 60 g / l, leucocytes-8,0 G / l ; myeloblaste -35 % ; promyelocyte necrophilia - 0,5 % ; stab neutrophils - 2% ; segmented of-21.5 % ; eosinophils - 6 % ; lymphocytes -32 % ; monocytes -3 %. What the diagnosis should be put . A * Acute leukemia B chronic leukemia C Rheumatoid arthritis D Thrombocytopenic purpura E deficiency anemia 12/10 The 25 - year-old woman half a year ago, I had an abortion. complaining about the disappearance of appetite, weakness , arthralgia , two weeks appeared dark urine , and jaundice , against which the General condition continues to deteriorate . Suspected viral hepatitis Some of Ismankulov viral hepatitis is likely to be positive, the patient? A * Anti - HBc IgM . B Anti - HEV IgM . C Anti - CMV IgM . D Anti - HBs E Anti - HAV IgM 13/20 The patient is 50 years complains of severe weakness , dizziness , skin spots. month ago had quinsy , was treated with antibiotics. Objective: total the condition is severe , the skin and the mucous membrane pale. On the face and trunk spots of different size , blue and brown. Palpation of the abdomen painless ,the liver +1.5 cm stands out from the edge of the right costal arch. General analysis of blood: EP -1,2 x1012 / l , NV - 50 g / l , color indicator 0,70 , platelets - 2x109 / l , unsophistication . ESR 55mm / hour. What is the diagnosis? A * Thrombocytopenic purpura B Hemorrhagic vasculitis , abdominal form C posthemorrhagic anemia D Myeloma E Hemophilia 14/27 The patient 24 years during the last two months is observed a growing headache , General weakness , dizziness , bleeding ( epistaxis , hemorrhage on kojei mucous membranes) . Lymph nodes , liver and spleen are not Tbilisians blood :Hb -50 g / l , R - 1,6 x1012 / l , p 1 , 0 , lake -2 , 0x109 / l , p - 1% , C -35 % , e -1 % , b - 1% , l -10% ,m 4% , trom 30x109/laki likely diagnosis ? A * Aplastic anemia B Acute leukemia C Deficiency anemia D-12 - deficiency anemia E Hemolytic anemia 15/39 Sick 62 years gospitalizirovn complaining increase cervical, supraclavicular, and axillary lymph nodes, weakness , increased sweating , low-grade fever within the last 3 months. In the analysis of blood - leikozita - h / l , in the formula - lymphocytes 72%. Research method is useful for further diagnosis ? A * Kilogramme B Lymphography C Lymphoscintigraphy D x-Ray examination E Thermography 16/43 The guy 15 years suffers from childhood atopic dermatitis allergic to shellfish meat. The last 3 months after purchase of aquarium fish , appeared rhinitis ,conjunctivitis , itch in the nose. The level of some immunological parameters determine the patient? A * IgE B IgJ C IgM D IgA E Circulating immune complexes 17/48 The patient is 19 years old, suffers from systemic lupus red , acute with kidney , heart , pleura , joints , it is planned to assign pathogenetic treatment. In the analysis of blood erythrocytes - 3,8 g / l , NV -120 g / l , laki. -2 , h / l ,thrombi . - 150 x 109 / l , urea to 6.9 mmol / L. Select the right treatment option . A * Prednisolone 60 mg / day . B Cyclophosphamide 200 mg in / in a day C Timolin 10 mg / m daily . D Laferon 5 million unit / m 2 times a week . E Levamisole 150 mg / day in the scheme . 18/50 In a patient with chronic lymphocytic leukemia has increased weakness , appeared jaundice. In an . blood : er - 2,1 g / l of HB - 55 g / l ; C.P. - 1,1; Reticuli . 51 per thousand. The bilirubin the General . - 80,3 mmol / l , on " govani - 65,3 mmol / l In urine increased level of urobilin Pryamoi test Kumbsa positive. What leading pathogenetic factors resulted in lower hemoglobin ? A * Autoimmune hemolysis B aplasia of hematopoiesis C Develop myelofibrosis D Deficiency folic acid E B12 Deficiency 19/51 Patient 53 years appealed to the neurologist with complaints of pain in the lower back On the x-ray of the spine and pelvis identified osteoporosis and large bone defects . In blood reasonable normohromnaja anemia , in the urine - proteinuria to 2.0 g / l . Total protein blood 107 g / lcuqae study should be undertaken to establish a definitive diagnosis? A * sternal puncture B Extended an . the blood. C ultrasound examination of abdominal cavity organs D cytochemical study E Radioisotope renografii 20/60 The patient K. 4 days ago got a rash on the skin, accompanied by itching . Bother bloating , dull pain in the right hypochondrium , constipation. The day before ate kopcheniya. Earlier similar reaction came after drinking excessive amounts of tomatoes , strawberries ,chocolate. Objective : on the skin of face , trunk , limbs urticarnae skin rashes . the total IgE level in a normal. What is the most likely diagnosis ? A * Pseudoallergy . B Idiosyncrasy . C Food Allergy. D Atopic dermatitis . E Chronic krapiwnice . 21/61 Patient 37 years , sold , complain of itchy skin of the hands , face and neck , which appears in contact with cold water , and in winter - at the exit to the street. An objective examination in open areas of skin melkorublenoy rash ,excoriation . Specify the diagnosis? A * Cold urticaria . B Scabies . C Atopic dermatitis . D pigment urticaria . E Contact dermatitis . 22/62 Woman, 40 years hospitalized with complaints of attacks of breathlessness , cough. Hurts 4 years. For the first time, choking, appeared at the patient stays in the village . subsequently the asthma disturbed during the cleaning. After 3 days of stay in hospital her state improved significantly. What are the most likely causative factor ? A * Household allergens. B Pollen. C Infectious . D Chemicals. E Psychogenic . 23/ 63 Patient K. had complained of wheezing shortness of breath , choking the appearance of asthma attacks at night 3-4 times a month, and day 2-3 times a week Objective : vesicular breath with a longer expiration , scattered dry , whistling grippe survey : FEV1 60 % of normal , daily fluctuations PSV 28%.to assign for short-attack at this stage of asthma? A * Salbutamol . B Flixotide . C Theopack . D Serevent . E tavegil . 24/ 82 In the rheumatology Department has been sick for 20 years with symptoms of arthritis. On agelica - redness in the form of butterflies . In the analysis of urine - protein 4.8 g / l . Fractionary presence at the patient of systemic lupus erythematosus . Additional mediclean is the most informative method for diagnosis verification? A * a blood test for antinuclear antibodies B General blood analysis C Immunological blood examination D a blood test for Le cells E a blood test for rheumatoid factor 25/ 83 The patient is 25 years , in connection with the transferred angina was appointed bicillin - 5 , which she did not. In 2 weeks after suffering a sore throat swelling of the face,decreased amount of urine , raised blood pressure. Creatinine of the blood - 340 umol / l , urea - 42 mmol / l What is the most likely diagnosis ? A *Acute glomerulonephritis . Acute renal failure B Acute glomerulonephritis , nephrotic syndrome C Acute glomerulonephritis , urinary syndrome D Acute glomerulonephritis , hypertension . E Chronic glomerulonephritis , chronic renal insufficiency 26/85 The patient 36, complaining of severe pain in the chest. Objectively: a serious condition. Intoxication syndrome -38 - 40C . Ps -88 bpm . Increased submandibular lymph nodes , sore . Respiration is weakened vesicular , in the projection of the lower lobe heard crepitus and mixed gripper : er - 3,0 x1012/L, Hb 100 g/L , Tr - 180x109 / l , Lc12x109/L / blasts 2% , promyelocyte -3 %, myelocyte -5%, metamyelocyte - 10 %, band cell- 15 %, segs -65 %. ESR -35 mm / hour. Toxic granularity of neutrophils and degenerative changes in them. What is the nature of the changes in the peripheral blood ? A *Leukemoid reaction myeloid type B Myeloproliferative process C Hyperleukocytosis D Bicytopenia E Blast transformation 27/ 106 Patient P. , 20, went to the doctor with complaints : fever , pain in the heart ,expressed General weakness , fatigue , joint pain , rashes on the skin , pain and a sense of gravity in the right hypochondrium. The complaint came after returning from a holiday. Objective : skin slightly yellowish , hemorrhagic rash , "butterfly" on the face Immunologicheskie blood analysis : reducing the number of T - suppressors , lupus cells , high titers of antinuclear antibodies , antibodies to smooth muscle . Put the diagnosis . A *Autoimmune hepatitis , type 1 B Systemic lupus erythematosus C Rheumatism D Autoimmune hepatitis , type 2 E Rheumatoid arthritis 28/111 Sick 22, after 5 weeks after hypothermia concerned about the fever ,weakness , muscle pain , inability to move independently . Objective: pain ,tightness of the muscles of the shoulders , legs ; active movement minimum, chest erythema; periorbital edema with heliotropic erythema, positive Gottron symptom. What research should be carried out for verification of diagnosis? A *Muscle biopsy B Transaminases C Joint x-ray D Titer ASLO E Rheumatoid factor 29/116 Patient 35 years, complains of reduced efficiency , long febrility , rash , pain in the small joints of hands. Objective: on the cheeks - erythematous "butterfly" , joints symmetrically swollen , in lungs - noise pleural friction. Conclusion: anemia , leukopenia ,lymphopenia . Urine - proteinuria , cylinderuria. Your diagnosis ? A *Systemic lupus erythematosus B Dermatomyositis C Reactive arthritis D Rheumatic fever E Rheumatoid arthritis 30/117 Patient 27 years, with bronchial asthma , was bitten by a bee . There was a feeling of pressure in the chest , shortness of breath , shortness of breath, a sense of heat in the upper half of the body , dizziness , expressed itching , seizures. Objectively: the noisy breathing, wheezing , AP - 90 /60 mm Hg , Ps - 110 bpm., heart - rhythmic tones, in lungs - hard breathing , dry wheezing. What group of drugs should be used in the first place? A *Glucocorticoids B Methylxanthines C Cardiac glycosides D Anticonvulsant E Analgesics 31/120 The woman of 42 years , suffering from chronic sinusitis, developed acute form of arthritis. The doctor prescribed treatment with acetylsalicylic acid. History of the propensity to allergic reactions, the patient was not. Suddenly after the injection, the patient developed bronchospasm. The most likely pathogenetic mechanism of bronchospasm are: A *Primary changed reactivity bronchi B Adrenergic imbalance C Infection-dependent D Atopic E Immunopathological 32/131 Patient 28 years complains of pain , swelling interphalangeal joints and left knee joint , morning stiffness . Objectively: the interphalangeal joints, metacarpophalangeal stiff , swollen , movement in them painful, not in full , minor atrophy intercostals muscles of the hand. An . blood : L - 9,6 h / l, ESR - 48 mm / hour. ; CRP + + + , Waaler-Rose Test 1:128 Diagnosis : A *Rheumatoid arthritis B Rheumatis arthritis C Deforming osteoarthrosis D Gouty arthritis E Reactive arthritis 33/145 Patient 19 years complained of shortness of breath during physical activity , increased body temperature to 37,5 oC , weakness. Suffering from chronic tonsillitis , a week ago there was a sharp aggravation . Objective: mild cyanosis, Ps -110 bpm. Weakened first tone, systolic murmur over the top. Blood test: Lc 8,9 h/L, ESR -27 mm/hour. ECG: sinus rhythm, R - 0,08 s, PQ - 0.25 s, QRS - 0,09 s. Your diagnosis: A * infectious - allergic myocarditis B Tonsillitis carditis C Constrictive pericarditis D Vegetative - vascular dystonia in cardiac type E Dilatation cardiomyopathy 34/165 The patient after receiving biseptol appeared oliguria, jaundice with a strong paleness of skin and mucous membranes , increased spleen. Blood test: er. - 2,2 G/L , Hb-60 g/L, Color index - 0,62 , Le - 14x109/l , reticulocytes 24 ‰. Indirect bilirubin in blood serum is 35 mmol/l. Urine and stool is dark color , the increased level stercobilin . What is the most likely diagnosis in this patient? A *Hemolytic anemia B Toxic hepatitis C Acute leukemia D Aplastic anemia E Obstructive jaundice 35/168 Patient M , 22 years old with suspected systemic lupus erythematosus complains of "flying" pain in the joints of the hands and feet , the temperature increase up to 38.5-39 oC for 3 weeks ,shortness of breath , palpitations , weakness. Objective: erythema on the cheeks and nose. In blood : Hb 90 g/L, platelets - 135x109, ESR - 43 mm / hour. Urine : protein - 2,66 g / l , red blood cells is 8-10. Which antibodies in blood test of patient is most significant for diagnosis? A *To the native DNA. B To the platelets. C To phospholipids. D Rheumatoid factor. E Crioglobuline . 36/170 Patient R. , 59 years old , was admitted in the rheumatology department on suspicion of scleroderma in a very serious condition. Objective: underweight, "a mask-like" face, osteolysis of ungual phalanges. In the blood - er. - 2,2 x1012/L, ESR - 40 mm / hour. Urine - raising the level of free hydroxyproline . One of the most probable stages of pathogenesis are: A *Appearance of antibodies to collagen . B Antibodies to native DNA. C Antibodies to uniform elements of blood. D Antibodies to striated muscles . E Antibodies to the vessel wall. 37/182 Patient, 24 years old , went to a doctor when found increased submandibular lymph nodes. Upon further examination by a doctor detected increased under-axillary and inguinal lymph nodes. On the x-ray of the chest - enlarged lymph nodes in the mediastinum. In blood test: er. 3,4x1012 /L , hemoglobin 100 g / l; a color parameter - 0,88 ,platelets - 190x109/L, leucocytes - 7,5 g / l , eosinophils - 8 % , stab - 2% ,segmented - 67 % , lymphocytes - 23% , ESR - 22 mm / hour. What the study shows for the verification of the cause of lymphadenopathy ? A* An Open biopsy of the lymph nodes. B Ultrasound examination of abdominal cavity organs C Tomography mediastinum. D Needle biopsy of the lymph nodes. E Sternal puncture . 38/192 In the trauma center hospital turned Builder 38 years immediately after the foot injury by hobnail. When inspecting the condition is satisfactory , on the sole of the right foot found wound . It is established that in the last three years three times conducted prevention of tetanus . What prevention is feasible at the present time? A * In / m to enter 0.5 ml . tetanus toxoid . B In / m enter 3000 IU of tetanus toxoid. C In / m to type 1 ml . tetanus toxoid , 3000 IU of tetanus toxoid. D Assign course of antibiotic therapy. E to Treat the wound with soap and water. 39/201 The child 2 years began to complain of a rash on the mucosa after a long antibiotic therapy about pneumonia. Objective : on the mucous membrane the mouth cavity , the tongue , the corners of the mouth is red spots covered by the crust , easy to remove shpatelem. Put the diagnosis . A * Candidiasis mucous membranes. B Pemphigus vulgaris C Multiforme exudative erythema. D Leukoplakia . E Streptococcal angular cheilitis. 40/202 A pregnant woman of 25 years with aggravated allergological history (Allergic rhinitis) in pregnancy 28 weeks after the stressful situation suddenly appeared loud wheezing , shortness of breath ,cyanosis face . On auscultation: breathing weakened, many dry wheezing with percussion - tympanic sound. After the attack in women was allocated a small amount of viscous sputum . What is the most likely diagnosis ? A * an Attack of bronchial asthma. B pulmonary Edema. C obstructive bronchitis. D pulmonary Embolism. E a Threat of miscarriage. 41/234 The patient 40 years , a homosexual , had complained of prolonged fever , night sweats , sudden weight loss , muscle pain , sore throat , joint pain , recurrent diarrhea. Then the examination detected generalized lymphadenopathy . What disease should be suspected ? A * AIDS B Limfogranulematose C Sepsis D Tuberculosis E Lymphocytic leukemia 42/238 Sick of 20 years. After a wasp sting developed angioedema , on the body rash in the form of blisters , papules . Emergency care should begin with : A *Prednisolone , antihistamines B Rheopolyglucin , gemodez C Norepinephrine , mezaton D Fresh frozen plasma , E - aminocaproic acid E Gipotiazid , furosemide 43/239 The patient aged 32 , pharmacist , worked with benzocaine . 5 days later on the hands appeared induration, skin and erythematous . Select the diagnosis . A *Contact dermatitis is an allergic B Atopic dermatitis C Psoriasis D Hemorrhagic vasculitis E Pigment urticaria 44/ 240 Patient N. , 25 years. Suddenly after taking shrimp developed itching in some areas of the body appeared blisters , redness . Put the diagnosis . A *Acute urticaria B Hemorrhagic vasculitis C Pigment urticaria D Psoriasis E Itching 45/ 241 The patient A. 22 years. Complaints of itching of the skin on the neck , ears. Sick since childhood. Father suffers from allergic rhinitis. When viewed erythema and lichenification on ears, neck, popliteal pits . The most likely diagnosis is : A *Atopic dermatitis B Seborrheic eczema C Psoriasis D Contact dermatitis E Itching 46/255 The patient is 25 years complains of weakness, dizziness, a hemorrhagic rash. Ill about month. In blood : er . - 1,0 x1012 / l , Hb - 37 g / l , color index - 0,9 , Le. - 1,2 x109 / l , platelets - 42x109 / L. the Method of the study will be most appropriate for the diagnosis? A *Sternal puncture B Biopsy spleen C Liver Biopsy D Coagulogram E Abdomen sonography 47/260 Patient 55 years complains of pain in the sternum and lumbar spine, ribs. In anamnesis - pathological fracture of the right Shin. In blood protein - 110g / l , positive M-gradient. Urine - Bence Jones protein. Your diagnosis ? A *Myeloma B Osteochondrosis C Angina FC D Glomerulonephritis E Neuralgia 48/263 Patient 20 years complaining on increase of body temperature to 38oC , shortness of breath , rapid heartbeat , swelling in the legs , pain in the joints. On the cheeks - erythema . Tachycardia , systolic noise at the top , a modest increase sizes of liver , spleen. In the analysis of blood : anemia , leukopenia , ESR 52mm / hour. In the analysis of urine: proteinuria - 5.6 g / l , red blood cells 20 - 30 , cylinders hyaline to 10 . Which method is necessary for diagnosis? A *Detection of antibodies to DNA B Ultrasound of the kidneys C Blood for About antistreptolysin D ECHO - KG E Renal Biopsy 49/280 Child 4 days. He was transferred from the maternity hospital with the symptoms of infectious toxicosis. During the inspection revealed: difficulty breathing through the nose , virginiamoreno - hemorrhagic discharge from the nose. Suspected early congenital syphilis . Which of the surveys will allow to confirm the suspicion ? A * the detection of specific antibodies in the blood. B Common blood test. C retinoscopy. D cerebrospinal fluid Examination. E Radiography tubular bones. 50/ 281 A pregnant woman in the second trimester diagnosed with primary syphilis , about which received adequate antibiotic treatment . Pregnancy informed . the neonatal period was uneventful , but a newborn baby found a high titer protivodiareynah antibodies. The child should be fed : A * Maternal breast milk. B donor breast milk. C Adapted mixture. D Adapted a mixture of soy . E Simple formula. 51/289 In a patient with extensive QS - myocardial infarction in the acute period of the disease observed the reduction of blood pressure to 80/ 60 mm Hg , mercatello fibrillation and blockade right bundle branch . On the 10th day of the disease detected the presence of ECG complexes QS-elevation of ST segment . In this case, the patient showed signs of pericarditis , fever and pleurisy. What complications of myocardial infarction said in this case ? A * Syndrome Dresler B left ventricular Aneurysm C cardiogenny shock D Electromechanical dissociation E pulmonary embolism 52/292 Patient S. 36 years , the pain of rheumatoid arthritis for 8 years. Two months ago appeared swelling of the left knee , resistant to treatment. objectively : synovitis of the left knee . The puncture of the joint and received 50 ml exudation. Which cells will be revealed in the study of articular punctate ? A * Rugocytes B LE cells C Cells Berezovsky D Erythrocytes E Eosinophils 53/320 Long distance driver 40 years , is ill for two months : General weakness , sweating , weight 12 kg , frequent prolonged diarrhea and recurrent respiratory infections. Objective : generalized lymphadenopathy , phenomena candidiasis of the oral cavity , in the faeces admixture of mucus and blood. We found a decrease in the number of T - helper cells , T4/T8 less than 0.5 . What is the most likely diagnosis ? A * AIDS B Shigellosis C Amoebiasis D Tuberculosis E Sepsis 54/339 The patient has a diagnosis of herpes zoster . The patient suffers from childhood diabetes , father and grandfather - bronchial asthma. A few days ago, I had food poisoning. Within 7 days took analgin about headache . when examining a patient found increased levels of antibodies against HIV. What factors has more pathogenic significance ? A * HIV - related immunodeficiency B Allergiesrelatives C Food poisoning D diabetes E analgesics E analgesics 55/353 Sick 30 years after their stay at work appealed to the dermatologist with complaints rashes all over the body . For the last 3 months notes the dramatic weight loss ,weakness , persistent fever . On the subject of any disease it is advisable to examine the patient ? A * AIDS B syphilis C Tuberculosis D cytomegalovirus infection E malignant skin neoplasms 56/363 Woman 36 years, suffering from hay fever for 7 years. Last 2 years in August - September ( during flowering ambrosia ) the patient complaints 2-3 asthma that are fixed 1 dose of salbutamol . Objectively : the temperature is 36,5oC , NPV - 18 min . , Pulse - 78 u . / Min . , BP-115/ 70 mm Hg Above the lungs - vesicular breath . The cardiac sounds sonorous , regular rhythm . The use of any drug will most effectively to prevent asthma attacks in critical patient season? A * Inhalation Intal B Inhalation Berotec . C atrovent Inhalation . D Reception suprastin . E Reception theopack . 57/370 Woman 63 years complained of General weakness , feeling of heaviness , pressure , fullness in epigastria , nausea , belching after meal . Sick about 15 years. Objectively: the temperature - 36,4 OS , NPV - 20/min , pulse-88/XB , BP - 115/MT . Skin and mucous pale. In blood : red cells is 2,0 g / l , NV - 100 g / l . Antibodies were detected obkladochnykh cells of the stomach. What is the most likely cause of anemia in this patient ? A * the Production of antibodies to the internal factor B a violation of the synthesis of hemoglobin C a violation of the synthesis of erythropoietin D malabsorption of iron E Increased consumption of iron 58 A child of 12 years during preventive examination detected diffuse enlargement of the thyroid gland of the II degree. Auscultation of the heart revealed muting heart sounds, HR 64/min Has a tendency to constipation. Found anemia. Increased levels of antibodies to thyroglobulin. What is the presumable reason specified symptoms? A. Endemic goiter. B. thyroid Cancer. C. Diffuse toxic goiter. D. Hyperplasia of the thyroid gland. E.* Autoimmune thyroiditis. 59. The patient 32 years with chronic viral hepatitis a dull, aching pain in the right hypochondrium, nausea, dry. The size of the liver by Kurlov - 13-12-11 cm, spleen +2 . AST - 3.2 mmol/GHL, Alt - a 4.8 mmol/GHL. Serological study revealed HBeAg, high concentration of DNA NV. Which of the following remedies is the drug of choice in the treatment of this patient ? A.*alpha interferon B. Arabinoside monophosphate C. Acyclovir D. Essentiale-Forte E. Rimantadine 60. A male 37 years when conducting pielografii using urografia arose itchy skin, swelling of the face, dizziness, fear of death. HELL 70/40 mm RT century, PS -130 beats in minutes noisy Breathing, wheezing heard in the distance, auscultation of breath weakened, single dry rales. What preparation you must enter the patient in the first place? A.*Adrenaline. B. Prednisolone. C. Lasix D. Suprastin. E. Aminophylline. 61. 25. Woman, 34 years old pain in acute 3 months ago, after acute respiratory infections hurt interphalangeal joint, and then after 2 weeks in the knee joints, morning stiffness, increased body temperature to 38os. Interphalangeal joints, metacarpophalangeal joint, knee swollen, stiff, swollen, hot to the touch. In the blood tests: ESR-45 mm/h, SLO +++, the reaction of Valer-Rose 1:128. What is the mechanism of the disease you can think of? A. *Autoimmune. B. Allergic. C. Exchange. D. Degenerative E. Dystrophic. 62. Woman, 35 years due to pneumonia was appointed ampicilin. In 20 minutes after intravenous injection of the drug the patient felt a sudden weakness, itching of the face, hands, nausea, cough, shortness of breath, pain in the chest. About-but: cyanosis, swelling of eyelids, face, with red rash. The pulse was 120 per minute, BP - 70/20 mm Hg heart sounds deaf, frequent breathing, surface, with different-sized moist rales. Varicose veins on the right leg. What is the most likely cause of sudden deterioration of the patient? A.*Anaphylactic shock B. Angioedema C. Urticaria D. Asthma attack E. Tromboembolia branches pulmonary artery 63. 30. The patient is 18 years of age suffering from seasonal bronchial asthma, atopic form, is in remission. Skin tests to house dust allergen 006 - +; 008 - +; the rye pollen - ++; wheat - +++. If the patient needs in specific giposencibilization if Yes, then what allergen? A. Yes, to the antigen wheat B. Yes, to the antigen rye C. Yes, to house dust 006, 008 D. * Yes, to the antigen of rye and wheat E. No 65. Man 18 years in connection with a headache took aspirin. 20 minutes later developed swelling of the eyelids, lips, appeared difficulty breathing, urticarnae elements on the skin. The father periodically noted swollen cheeks, lips after the extraction of teeth. Response inhibition of migration of leukocytes with aspirin negative. Immunoglobulin E - 115 ng/ml what is the most likely diagnosis. A.*Hereditary angioedema B. Angioedema C. the Attack of bronchial asthma D. Allergic dermatitis E. Pigment urticaria 66. 40. Patient 23 years taken to the emergency room with contaminated knife cut wound of the right foot. Initial debridement, entered tetanus serum. Some time later, the patient's condition worsened dramatically: there was a sudden weakness, dizziness, frequent heartbeat. On-but: there paleness of skin, cold sweat, rapid pulse weak filling up to 100 beats/min, HELL 90/40 mm RT. Art. and therefore there was a sharp deterioration of the patient? A.* anaphylactic shock B. hemorrhagic shock C. pain shock D. toxic shock E. drug ( serum ) disease. 67. 42. The clinic received the patient is 18 years with complaints expressed shortness of breath, skin itch. Acutely ill, about an hour later, after taking ampicillin. In childhood urticaria, food polyallele. About-but: periorbital edema, redness and swelling of the face. The breath wheezing. PS 96 1 minutes, HELL 80/50 mm RT. senior Drug emergency? A.*Hydrocortisone B. Aminophylline C. Diphenhydramine D. Dopamine E. Mezaton 68. 47. In women 35 years of age 30 minutes after intramuscular injection ampicilina there are sharp weakness, itching of the face and hands, nausea, cough, shortness of breath, pain in the chest. About-but: cyanosis, swelling of eyelids, face, neck, skin wet with red rash. Pulse - 120/min ,AD - 70/20 mm Hg, heart sounds deaf, frequent breathing, surface with a large number of heterogeneous moist rales. With the introduction of a drug, you should immediately begin therapy? A.* Adrenaline B. Prednisolone C. Astmopent D. Eufillin E. Dopamine 69. 50. The man who had 2 days ago sexual contact, as it turned out later, with an HIVinfected partner, has addressed with the request to eliminate the possibility of infection. When it is necessary to carry out the first study of antibodies to HIV? A.*a month after sex B. on the day of treatment C. in 3 months D. in 6 months E. in 1.5 years . 70. The 12-year-old girl after drinking two aspirin for 4-5 hours the body temperature rose to 39-40 degrees. Complains of the total nedomoganie, dizziness, unexpected appearance of red spots on skin blistering or peeling of the skin with eroded surface. Lesions on the skin was like a second-degree burn. Symptom Nikolsky - positive. What is the most likely diagnosis? A. * Acute epidermal necrolysis syndrome Layla. B. Bladderwort vulgar. C. Polymorphic exudative erythema. D. Bolotny dermatitis. E. dermatitis Herpetiformis of during. 71. A woman 20 years 8 years in August-September occurs rhinitis, conjunctivitis, and last year joined asthma or cough with difficult breathing. When conducting skin tests revealed hypersensitivity to ragweed pollen. What interleukin is critical synthesis of antibodies, obuslavlivayuschih disease? A..* IL 4. B. IL 1. C. IL 2. D. IL 3. E. IL 6. . 72. The girl of 18 years after extraction of the tooth appeared solid sickly pale facial swelling, abdominal pain without clear localization, nausea. Similar symptoms occurred several times previously, after stress or before menstruation. And passed without treatment within 3-4 days. Specify the cause of the above-mentioned condition of the patient. A. Cholinergic imbalance. B. Giperergicakie reaction I type. C. Giperergicakie reaction III type. D.*Shortfall of C1 inhibitor of complement. E. Pseudo allergic reaction.