Pedigree - Sickle Cell Inheritance ?`s

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Conclusion
1. Why is sickle cell anemia classified as a recessive disorder?
2. If Anna had a child with a man with sickle cell anemia, predict whether that child
would also have sickle cell anemia. Explain the reasoning using a punnett square
and describe the information you used to make your prediction.
3. If a person is a carrier for sickle cell and they have a child with another person
who is a carrier for sickle cell, what is the chance that their child will be a carrier
for sickle cell? What is the chance their child will have “full” sickle cell? What is
the chance that their child will not have sickle cell? Create a punnett square to
answer this question.
4. Use the letters “S” or “s” to show the alleles (genotype) of a person who is
homozygous recessive, homozygous dominant and for a person who is
heterozygous
Homozygous recessive: _____________ (does this person have sickle cell?)
Homozygous dominant: _____________ (does this person have sickle cell?)
Heterozygous: ________________ (does this person have sickle cell)?
© 2013 Project Lead The Way, Inc.
PBS Activity 3.4.1 Family Inheritance – Page 1
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