Name____________________________________________
Mitosis-Meiosis Quest
Directions: Select the answer that best completes each question below
1.
Which of the following is NOT true of meiosis?
A. During metaphase, spindle microtubules first come into contact with chromosomes
B. The chromosome number in the newly formed cells is half that of the parent cell
C. The homologous chromosomes line up along the equator, or metaphase plate of the cell
D. The cytoplasm of the cell and all its organelles are divided approximately in half
E. In anaphase II, the sister chromatids travel to opposite ends of the cell
2. The restoration of the diploid chromosome number after halving in meiosis is due to:
A. Synapsis
B. Fertilization
C. Mitosis
D. DNA replication
E. Chiasmata
3. During the first meiotic division (meiosis I),
A. Homologous chromosomes separate
B. The chromosome number becomes haploid
C. Crossing over between nonsister chromatids occurs
D. Paternal and maternal chromosomes assort randomly
E. All of the above
4. A cell with a diploid number of 6 could produce gametes with how many different combinations of maternal and
paternal chromosomes?
A. 6
B. 8
C. 12
D. 64
E. 128
5. The DNA content of a diploid cell is measured in the G1 phase. After meiosis I, the DNA content of one of the
two cells produced would be:
A. Equal to that of the G1 cell
B. Twice that of the G1 cell
C. One-half of the G1 cell
D. One-fourth that of the G1 cell
E. Impossible to estimate due to the independent assortment of homologous chromosomes
6. Meiosis II is similar to mitosis because:
A. Sister chromatids separate
B. Homologous chromosomes separate
C. DNA replication precedes the division
D. They both take the same amount of time
E. Haploid cells are produced
7. Which of the following is NOT true of homologous chromosomes?
A. They behave independently in mitosis
B. They synapse during the S phase of meiosis
C. They travel together to the metaphase plate in prometaphase of meiosis I.
D. Each parent contributes one set of homologous chromosomes to an offspring
E. Crossing over between nonsister chromatids of homologous chromosomes is indicated by the presence of
chiasmata
8. If the four cells in figure one below resulted from cell division of a single cell with a diploid chromosome number
of 2n=4, what best describes what just occurred?
A. Normal meiosis
B. Translocation
C. Inversion
D. Nondisjunction
9. Independent orientation of chromosomes at metaphase I results in an increase in the number of:
A. Gametes
B. Homologous chromosomes
C. Possible combinations of characteristics
D. Sex chromosomes
10. Which of the following statements is correct?
A. Crossing over occurs in prophase I of meiosis and metaphase of mitosis
B. DNA replication occurs once prior to mitosis and twice prior to meiosis
C. Both mitosis and meiosis result in daughter cells identical to the parent cells
D. Nuclear division occurs in once in mitosis and twice in meiosis
E. Synapsis occurs in prophase of mitosis
11. A mutation results in a cell that no longer produces a normal protein kinase for the M phase checkpoint. Which
of the following would likely be the immediate result of this mutation?
A. The cell would prematurely enter anaphase
B. The cell would never leave metaphase
C. The cell would never enter metaphase
D. The cell would never enter prophase
E. The cell would undergo normal mitosis, but fail to enter the next G1 phase
Use the following information to answer questions 12 below:
A student is looking through a light microscope (450x) at a squashed and stained onion root tip. Some, but not all, of the
cells have clearly visible chromosomes strands.
12. When a cell is in anaphase of mitosis, which of the following will he see?
A. A clear area in the center of the cell
B. Chromosomes clustered at the poles
C. Individual chromatids separating
D. Chromosomes clustered tightly at the center
E. Formation of vesicles in at the midline
13. Which of the following describe(s) cyclin-dependent kinase (Cdk)?
A. Cdk is inactive, or turned off in the presence of cyclin
B. Cdk is present throughout the cell cycle
C. Cdk is an enzyme that attaches phosphate groups to other proteins
D. Cdk is inactive or “turned off”, in the presence of cyclin and it is present throughout the cell cycle
E. Cdk is present throughout the cell cycle and is an enzyme that attaches phosphate groups to other proteins*
14. A particular cyclin called cyclin E forms a complex with Cdk2 (cyclin-dependent kinase 2). This complex is
important of the progression of the cell from G1 into the S phase of the cell cycle. Which of the following
statements is correct?
A. The amount of free cyclin E is greatest during the S phase
B. The amount of free Cdk2 is greater during G1 compared to the S phase
C. The amount of free cyclin E is highest during G1*
D. The amount of free Cdk2 is greatest during G1
E. The activity of the cyclin E/Cdk2 complex is highest during G2
15. Which of the following triggers the cell’s passage past the G2 checkpoint into mitosis?
A. PDGF
B. MPF*
C. Protein kinase
D. Cyclin
E. Cdk
16. Besides the ability of some cancer cells to over proliferate, what else could logically result in a tumor?
A. Metastasis
B. Changes in the order of cell cycle stages
C. Lack of appropriate cell death*
D. Inability for form spindles
E. Inability of chromosomes to meet at the metaphase plate
17. The karyotype of one species of primate has 48 chromosomes. In a particular female, cell division goes awry and
she produces one of her eggs with an extra chromosome (25). The most probable source of this error would be a
mistake in which of the following?
A. Mitosis in her ovary
B. Metaphase I of one meiotic event
C. Telophase II of one meiotic event
D. Telophase I of one meiotic event
E. Either anaphase I or II*
18. Homologous chromosomes move toward opposite poles of a dividing cell during:
A. Mitosis
B. Meiosis I*
C. Meiosis II
D. Fertilization
E. Binary fission
19. A female with a paternal set of one orange and one long gene chromosome and maternal set comprised of one
blue and one short gene chromosome is expected to produce which of the following types of eggs after meiosis?
A. All eggs will have maternal types of gene combinations
B. All eggs will have paternal types of gene combinations
C. Half the eggs will have maternal and half will have paternal combinations
D. Each egg has a one-fourth chance of having either blue ling, blue short, orange long, or orange short
combinations*
E. Each egg has a three-fourths chance of having blue long, one-fourth blue short, three-fourths orange ling, or
one-fourth orange short combinations
20. How does the sexual life cycle increase the genetic variation in a species?
A. By allowing crossing over*
B. By allowing fertilization
C. By increasing gene stability
D. By conserving chromosomal gene order
E. By decreasing mutation frequency