PredictFold-PSS-3D1D: A Protein Fold Recognition Server for Predicting Folds from the Twilight Zone Sequences By:Ganesan, K (Ganesan, Kaliappan)[ 1 ] ; Parthasarathy, S (Parthasarathy, Subbiah)[ 1 ] CURRENT BIOINFORMATICS Volume: 8 Issue: 5 Pages: 552-556 Published: NOV 2013 View Journal Information Abstract The PredictFold-PSS-3D1D is an online protein fold recognition web server used to predict the possible folds from the twilight zone protein sequences. In this server, an improved 3D1D profile method (Ganesan and Parthasarathy, J. Struct. Funct. Genomics, 12, 181-189, 2011) is employed, wherein, the inclusion of predicted secondary structure information improves fold recognition. The PredictFold-PSS-3D1D server accepts amino acid sequences and their predicted secondary structure data as input and aligns them with the 3D1D profiles of known SCOP folds in a database. The alignments are ranked by the z-values and P-values. The top 5 ranks of the SCOP folds from the database are listed along with a link to 'View SCOP details'. The folds with z-values >= 3.0 and P-values <= 0.05 are indicated as 'Predicted Fold' for the given query twilight zone protein sequence. This server is available in our PredictFold web server at http://bioinfo.bdu.ac.in/pss3d1d/. Keywords Author Keywords:3D1D profile; protein fold recognition; protein secondary structure server; twilight zone sequences KeyWords Plus:SECONDARY STRUCTURE Author Information Reprint Address: Parthasarathy, S (reprint author) Bharathidasan Univ, Sch Life Sci, Dept Bioinformat, Tiruchchirappalli 620024, Tamil Nadu, India. Addresses: [ 1 ] Bharathidasan Univ, Sch Life Sci, Dept Bioinformat, Tiruchchirappalli 620024, Tamil Nadu, India E-mail Addresses:bdupartha@gmail.com Funding Funding Agency Grant Number Department of Information Technology (DIT), Govt. of India, New Delhi DIT View funding text Publisher BENTHAM SCIENCE PUBL LTD, EXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES Categories / Classification Research Areas:Biochemistry & Molecular Biology; Mathematical & Computational Biology Web of Science Categories:Biochemical Research Methods; Mathematical & Computational Biology Document Information Document Type:Article Language:English Accession Number: WOS:000325754000005 ISSN: 1574-8936 eISSN: 2212-392X Other Information IDS Number: 235WX Cited References in Web of Science Core Collection: 9 Times Cited in Web of Science Core Collection: 0