MINISTRY OF HIGHER AND SECONDARY SPECIAL EDUCATION
MINISTRY OF HEALTH OF UZBEKISTAN
TASHKENT MEDICAL ACADEMY
DEPARTMENT OF ENDOCRINOLOGY
"APPROVED"
Vice Rector for Academic Affairs
prof._______Teshayev O.R.
"___" _______________ 2012.
WORK PROGRAM
the discipline of "Endocrinology"
Area of expertise - 720000 "Healthcare"
Direction of Education:
5720100 "medicine"
5140900 - Professional Education (General Medicine)
TASHKENT - 2012.
purpose:
- Teaching fundamental bases the role of the endocrine system in the life of an
organism and the importance of the neuroendocrine regulation to maintain
normal homeostasis;
- Learning the diagnosis and principles of treatment of major diseases of the
endocrine system.
objectives:
- To teach students the basic concepts of endocrine diseases, knowledge of the
etiology, pathogenesis, classification, clinical manifestations and treatment
guidelines;
- Trained to diagnose the most common form of endocrine diseases.
Content of the subject
Disorders of the hypothalamic-pituitary axis
Hormonal regulation of metabolism in health and disease.
The structure of the pituitary gland. The biological effect of hormones of the
pituitary and hypothalamus. Feedback mechanism.
Disorders of the hypothalamic-pituitary system: acromegaly, gigantism, dwarfism.
Disorders of the hypothalamic-pituitary system: diabetes insipidus, syndrome
Sheehan, pituitary Cushing (etiology, pathogenesis, clinical manifestations,
diagnosis, treatment).
Obesity
Obesity: classification, etiology, pathogenesis, clinical features, diagnosis,
treatment
Diabetes mellitus
Diabetes mellitus: epidemiology, etiology, pathogenesis, classification. Treatment
of diabetes. Diet, oral hypoglycemic agents, indications and contraindications to
their destination.
Insulin therapy (indications, types of insulin, insulin dose calculation,
complications of insulin therapy).
Coma:
hypoglycemia
and
ketoatsidoticheskaya
(etiology,
pathogenesis,
differential diagnosis, emergency care)
Thyroid disease
Synthesis and biological effects of thyroid hormones. Thyroid disease.
Classification. Goiter (etiology, pathogenesis, treatment and prevention
methods.) Thyroiditis.
Hypothyroidism.
Diffuse
toxic
goiter
(etiology,
pathogenesis,
clinical
manifestations, diagnosis, treatment criteria).
Diseases of the parathyroid gland (hyper-, hypoparathyroidism (etiology,
pathogenesis, clinical manifestations, diagnosis, current treatments)
Adrenal disease
Adrenal glands structure. The biological effect of adrenal hormones. Acute and
chronic
insufficiency
of
the
adrenal
cortex.
Conn's
syndrome.
Pheochromocytoma. Cushing's syndrome (etiology, pathogenesis, clinical
manifestations, diagnosis, treatment).
Diseases accompanied by polyuria and polydipsia
Diabetes insipidus. Pathogenesis of clinical symptoms. Psychogenic polydipsia.
Differential diagnosis with enuresis, pyelitis, and glomerulonephritis, treatment.
Conn's
syndrome.
Differential
diagnosis
of
diabetic
nephropathy.
Hyperparathyroidism. Etiology. Pathogenesis of polyuria and polydipsia.
Differential diagnosis of renal form of diabetes insipidus.
Diagnosis, treatment.
Diabetes. Risk factors for diabetes prevention techniques. Pathogenesis of
polyuria, polydipsia, and other clinical symptoms. Differential diagnosis with
psevdoglyukozuriey, renal glycosuria, gestational diabetes. Diagnosis of
intermediate forms of hyperglycemia. Treatments 1 and 2 of types of diabetes.
Insulin therapy.
Severity of diabetes. Criteria for compensation and decompensation of diabetes.
Surveillance of patients with diabetes mellitus during pregnancy and when joining
intercurrent diseases, indications for hospitalization. Clinic and diagnosis of
retinopathy, nephropathy and neuropathy. Prevention of complications,
rehabilitation.
Goiter. Diseases accompanied by hyperplasia
thyroid.
Iodine deficiency disorders and methods of prevention. Nodular goiter and mixed:
diagnosis, diagnostic methods. Indications strumectomy.
Graves' disease. Differential diagnosis with neuro dystonia, tuberculosis,
rheumatism, thyrotoxic adenoma, cachexia different genesis. Pathogenesis of
clinical symptoms. Methods of treatment, choice of doses. Hyperthyroidism
during pregnancy.
Thyroiditis (acute, sub-acute), Zob Riedel: etiology, pathogenesis, clinical picture.
Differential diagnosis of thyroid cancer, treatment, complications.
Autoimmune thyroiditis. The clinical picture, stage, form. Differential diagnosis
with endemic goiter. Treatment. Complications.
Diseases associated with obesity
Constitutional-exogenous obesity: causes, stages, degrees, methods for
identifying overweight. Modern methods of treatment.
Hypothyroidism. Clinical and etiological forms. Differential diagnosis with anemia
of various origins, constitutional-exogenous obesity, kidney and intestine.
During hypothyroidism during pregnancy and especially treatment. Hormone
replacement therapy, the selection of doses.
Cushing's disease. Differential diagnosis of various forms of Cushing. The
pathogenesis of obesity. Differential diagnosis with primary hypogonadism and
false adipozogetitalnoy dystrophy. Prevention, treatment.
Diseases associated with
hypertension
Feohromatsitoma. Clinical forms. Differential diagnosis with hypertension and
other neendokrinnymi Hypertension. Complications, treatment, diagnosis.
Conn's syndrome. The etiology and pathogenesis of major clinical sipmtomov.
Differential diagnosis with secondary aldesteronizmom, treatment, complications.
Disease and Cushing's syndrome. Differential diagnosis with diabetes, puberty
and youth dispituitarizmom, acromegaly. Principles of treatment.
Diseases associated with
hypotension
Syndrome Shiena-Symonds. The pathogenesis of the main clinical symptoms.
Form, severity, hormone replacement therapy. Prevention, complications.
Acute and chronic adrenal insufficiency: the causes and pathogenesis of
hypotension and other clinical symptoms. Differential diagnosis with neuro
dystonia, hemochromatosis, scleroderma, enteritis, malobsorbtsii syndrome,
pellagra.
Impaired consciousness.
Coma in endocrinology.
Hypoglycemic coma. Reasons. The factors that trigger the development of
hypoglycemic coma in patients with diabetes mellitus. Pathogenesis of clinical
symptoms. Stage. Providing care in a clinic.
Hyperglycemic
coma:
ketoatsidoticheskaya,
hyperosmolar,
laktoatsidemicheschkaya. Reasons for the development. Differential diagnosis of
hepatic, uremic hypoxic komami. Assist pre-hospital and hospital stages.
Impaired growth
Diseases accompanied vysokorostlostyu. Gigantism. Differential diagnosis with
Klinefelter's syndrome, Marfan and genetic vysokorostlostyu.
Acromegaly. Differential diagnosis with akromegaloidnymi syndromes. Male
hypogonadism: etiology, clinical and pathogenic forms, diagnosis, hormone
replacement therapy, complications and their prevention.
Diseases accompanied nizkokorostlostyu. Dwarfism. Differential diagnosis with
Turner's syndrome, Chondrodystrophy, congenital hypothyroidism, genetic forms.