Background info on vaccines/herd immunity

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http://www.autismsciencefoundation.org/autismandvaccines.html
Listing of scientific articles showing no connection between autism and vaccinations or their schedule.
http://www.autismsciencefoundation.org/sites/default/files/CHOP1.pdf really nice newsletter format
summary of this
http://www.autismsciencefoundation.org/sites/default/files/CHOP2.pdf General vaccine info
Herd Immunity Thresholds for various diseases http://commonhealth.wbur.org/2013/08/low-statevaccine-rates
http://media.wbur.org/wordpress/15/files/2013/08/too-many-children-go-unvaccinated_2-620x580.jpg
http://www.vaccines.gov/diseases/diphtheria/index.html info on specific vaccines, rates, risks
also immune system
http://www.software3d.com/Home/Vax/Immunity.php vaccination software herd immunity
http://www.motherjones.com/environment/2014/02/vaccine-exemptions-states-pertussis-map
http://jama.jamanetwork.com/article.aspx?articleid=203593#REFJOC60132-7
Nonmedical Exemptions to School Immunization RequirementsSecular
Trends and Association of State Policies With Pertussis Incidence
Saad B. Omer, MBBS, MPH; William K. Y. Pan, DrPH, MS, MPH; Neal A. Halsey, MD; Shannon Stokley,
MPH; Lawrence H. Moulton, PhD; Ann Marie Navar, MHS; Mathew Pierce, JD, MPH; Daniel A. Salmon,
PhD, MPH
[+] Author Affiliations
JAMA. 2006;296(14):1757-1763. doi:10.1001/jama.296.14.1757.
Figure 1. Mean Percentage and Interquartile Ranges of Nonmedical Exemptions for States That Only Permit Religious Exemptions and States
That Permit Personal Belief Exemptions, 1991 Through 2004
Pertussis Incidence and Associations With State Policies
The mean annual incidence of pertussis in the 50 states and the District of Columbia is presented
in Figure 3. Vermont had the highest incidence at 12.8 per 100 000. In unadjusted analysis,
pertussis incidence in states allowing personal belief exemptions was more than twice as high as
in states that only offered religious exemptions (IRR = 2.06; 95% CI, 1.77-2.4). States with easy
procedures for granting exemptions were associated with a 90% higher incidence of pertussis
(IRR = 1.90; 95% CI, 1.06-2.28) and states with a medium difficulty for granting exemptions
were associated with a 27% higher incidence of pertussis (IRR = 1.27; 95% CI, 1.06-1.51)
compared with states with difficult procedures to obtain exemptions. Pertussis incidence was
41% higher for states that considered parental signature as sufficient proof of immunization
compared with states that did not (IRR = 1.41; 95% CI, 1.12-1.77) (Table 2).
From Wikipedia IRR Incidence Rate Ratio A rate ratio (sometimes called an incidence
density ratio) in epidemiology, is a relative difference measure used to compare the incidence
rates of events occurring at any given point in time. A common application for this measure in
analytic epidemiologic studies is in the search for a causal association between a certain risk
factor and an outcome.[1]
[2]
Where incidence rate is the occurrence of an event over person-time, for example person-years.
Note the same time intervals must used for both incidence rates.
Availability of personal belief exemptions and easily obtained exemptions were associated with
increased pertussis incidence. The small number of states with acceptance of parental signature may
have limited the power of this comparison. These study findings indicate that state exemption policies
affect vaccine exemption rates as well as pertussis incidence. States should examine their exemption
policies to ensure control of pertussis and other vaccine-preventable diseases.
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6230a3.htm
CDC data on kindergarten immunization, by state, 2012-2013
State
% surveyed
Mmr
alabama
100
92.8
Arkansas
96.3
85.9
Idaho
100
88.4
Indiana
83
95.4
DTAP
92.8
82.9
88.3
90
Minnesota
Pennsylvania
Missouri
Colorado
wisconsin
washington
National median
100
97.5
5.9
0.5%
1.8
94.7
96.3
87
96.7
85.7
92.8
91.7
94.5
96.7
90.7
96.5
82.9
96.1
91.9
95.1
FIGURE. Estimated percentage of children enrolled in kindergarten who have been exempted from
receiving one or more vaccines* — United States, 2012–13 school year
http://www.cdc.gov/pertussis/about/faqs.html
DTAP is 80-90% effective, with protection at 90% one year after all five doses. Decreases with time, :
70% fully protected after five years, with other 30% partially protected
A person with pertussis can infect 12-15 other people
Vaccines trigger the immune response and create Memory B cells to a specific virus. Flu, measles,
mumps, chicken pox, HPV, meningitis, polio, etc.
Vaccines use “dead” viruses (can’t cause disease), very weakened viruses, or simply parts of viruses with
antigen to trigger the immune response.
You have to have vaccines BEFORE being exposed to the disease-causing (pathogenic) virus or
bacterium.
Bacterial vaccines exist, using similar types of antigens. Vaccines are available against the bacterial
diseases tuberculosis, diphtheria, tetanus, pertussis, Haemophilus influenzae type B, cholera, typhoid,
and Streptococcus pneumoniae.
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