Group three Theme: OCCUPATIONAL HEALTH AND SAFETY Title: Characterization of health and safety hazards among workers managing zoonotic diseases in East and Central Africa 1Celsus Sente, 2Stephen S. Kishinhi, 1Rawlance Ndejjo, 3WubitTafese and 1Andrew Seruma Kizito 1. Uganda, 2. Tanzania, 3. Ethiopia Introduction Zoonosesare diseases and infections that are naturally transmitted between vertebrate animals and humans and vice versa.Endemic zoonotic diseases such as anthrax, bovine tuberculosis, brucellosis, cysticercosis, echinococcosis (hydatid disease), rabies and zoonotic trypanosomiasis (sleeping sickness) occur throughout the African continent where conditions for their maintenance and spread exist (WHO, 2007). Recent studies indicate that more than threefourths of communicable human diseases are zoonotic in origin (Woolhouse and Gowtage- Sequeria 2005), including diseases associated with significant mortality and morbidity such as avian influenza (H5N1), severe acute respiratory syndrome (SARS), Ebola virus, and Nipah virus. Some of these zoonotic diseases originate in wildlife and others in domestic livestock species; many have the potential to affect humans through a livestock–human interface (Cleaveland et al. 2001) in which domestic livestock can act as “amplifier hosts” (Keesing et al. 2010) for diseases that they contract from wildlife and then pass to humans through frequent and close contact. Workplace exposure to zoonotic pathogens, agents transmitted to humans from vertebrate animals or their tissues, is an occupational hazard.Occupational health and safety hazards have been characterized as: physical hazards (ionizing radiation due to x-rays); chemical hazards-allergens, toxic chemicals in laboratories (formaline and xylene in histopathology labs), anesthetic gases (halothane, nitrous oxide), cytotoxic drugs used in treating cancers; mechanical and ergonomic hazards- low back pain in nurses due to inappropriate lifting of patients; biological-blood borne infections such as hepatitis B & C, HIV, hemorrhagic fevers like ebola. Pathologists and postmortem technicians are at risk of TB. Psychological hazards as a result of stress among workers. The magnitude of these hazards among workers managing zoonotic diseases remains unknown. There is also growing interest in promoting cooperation between medical and veterinary sectors, as captured in the concept of “one health” (Zinsstagetal. 2011). Scientific research is now focusing on the interActionsbetween humans, domestic animals, and wild animals to better understand the mechanisms of disease emergence and transmission, thus informing more effective policies for communicable disease prevention and control. Problem statement: There has been an increase in occupational health and safety related conditions. These include death, severe injuries, disability, chronic infections, cross infection,trauma. The prevalence and incidence of zoonotic diseases has also increased in the recent past. Workers of different backgrounds are involved in the management of these diseases including both human and animal health workers. These workers are increasingly exposed to zoonotic diseases. When the workers are faced with occupational health and safety conditions, they would require treatment which is many times costly, working hours are also lost during the treatment of these conditions, there will be a reduction in the work force in case of serious effects like disability or death, a reduction in productivity and an increase in poverty since most workers are usually bread winners in their households. The government has invested in vaccines, equipped health facilities, stocked drugs but these efforts have not solved the problem. The knowledge of workers on the hazards in their environment is not known. There is need to further understand the hazards affecting this workforce and their predisposing factors in order to design effective strategies for the prevention of these hazards. Research questions 1. What occupational health and safety hazards affect workers managing zoonotic diseases? 2. What are the predisposing factors associated with the hazards? 3. What do workers managing zoonotic diseases know about hazards in their working environment? 4. What control measures are in place to minimize the impact of the hazards? Aim and Objectives General Objective To characterize health and safety hazards among workers managing zoonotic diseases in East and Central Africa in order to design effective strategies to control the hazards. Specific objectives 1. To identify the occupational health and safety hazards affecting workers managing zoonotic diseases 2. To determine the predisposing factors associated with the hazards 3. To assess the knowledge of workers managing zoonotic diseases about hazards in their working environment 4. To identify the control measures in place to minimize the impact of the hazards Outcomes Characterization of hazards will enable their further understanding such that effective control strategies can be designed. This will ensure a reduction of the hazards. With such a reduction, there will be improvement in the health status of workers, reduced expenditure in the treatment of occupational health and safety conditions and therefore reduced health expenditure, improved productivity of the workers and better service delivery to the citizens of East and central African countries. References WHO, 2007.Applying the “One Health” Concept Report of a Joint WHO/EU/ILRI/DBL/FAO/OIE/AU Meeting ILRI Headquarters, Nairobi, 13–15 November 2007 Woolhouse MEJ, GowtageSequeria S. 2005. Host range and emerging and reemerging pathogens. Emerging Infect Dis 11:1842–1847. Cleaveland S, Laurenson MK, Taylor LH. 2001. Diseases of humans and their domestic mammals: pathogen characteristics, host range and the risk of emergence. PhilosTrans R SocLond B BiolSci 356:991–999 Keesing F, Belden LK, Daszak P, Dobson A, Harvell CD, Holt RD, et al. 2010. Impacts of biodiversity on the emergence and transmission of infectious diseases. Nature 468:647–652. Zinsstag J, Schelling E. WaltnerToews D, Tanner M. 2011. From ‘one medicine’ to ‘one health’ and systemic approaches to health and wellbeing. Prev Vet Med 101:148–156.