AS Biology_Unit 2: Genetic Diversity Fact File Genetic diversity is the differences in the DNA of members of the same species within a population. Genetic diversity is increased through: Mutation Crossing over in Meiosis I Random segregation Random fertilisation of gametes Random mating (out-breeding) Genetic diversity is reduced through: Selective breeding Asexual Reproduction The Founder Effect Genetic Bottlenecks In-breeding Genetic diversity arises by mutations in the DNA forming new alleles. The combined effects of when chromatids cross over and when random segregation occurs in meiosis I along with random fertilisation produce new combinations of existing alleles. Another way is when different alleles are introduced into a population when individuals from another population migrate into them and reproduce, which is also known as ‘gene flow’. The Founder Effect The Founder Effect occurs when a few individuals of a population colonise a new, isolated region. Only a small number of organisms have contributed their alleles to the gene pool therefore their alleles may not be representative of the original population. Due to the narrower range of alleles, inbreeding may take place and as a result over time, some alleles found in the original population may be completely lost if individuals fail to produce offspring, who can carry the alleles. Examples of the Founder Effect: The Afrikaner population of Dutch settlers in South Africa is descended mainly from a few colonists. Today, the Afrikaner population has an unusually high frequency of the gene that causes Huntington’s disease, because those original Dutch colonists just happened to carry that gene with unusually high frequency. Genetic Bottlenecks A genetic bottleneck is produced the population of a species reduces suddenly due to unselective natural disasters or gradual environmental changes such as earthquakes, floods and volcanic eruptions. The few individuals left will only have a small range of alleles between them, so if they reproduce and the population increases again there will be reduced genetic diversity because many of the original variety of alleles maybe lost in individuals who didn’t survive or some alleles maybe overrepresented by the surviving individuals. Examples of Genetic Bottlenecks: Northern elephant seals have reduced genetic variation probably because of a population bottleneck humans inflicted on them in the 1890s. Hunting reduced their population size to as few as 20 individuals at the end of the 19th century. Their population has since rebounded to over 30,000—but their genes still carry the marks of this bottleneck: they have much less genetic variation than a population of southern elephant seals that was not so intensely hunted. How does the selection of high-yielding breeds of domesticated animals and plants influence genetic diversity? The selection of high-yielding breeds of domesticated animals and plant has an influence on genetic diversity because it reduced it. When the desired alleles are selected to breed an organism, the number of alleles present in the new organism is reduced. Selective breeding Selective breeding is also known as artificial selection, which involves humans choosing desired characteristics for parent individuals to produce high-yielding breeds of domesticated animals and strains of plants. Selective breeding reduces genetic diversity because the variety of alleles in a population is limited to a small number of desired alleles. This means that when an organism with the desired characteristic has been produced, only that one type of organism will be continually be bred. The selection of high-yielding breeds of domesticated animals and plants influence genetic diversity by reducing it because similar organisms with similar characteristics will be reproduced again and again meaning that similar alleles will be bred together over many generations. Examples of selectively bred plants and animals: 1. Maize was bred from an unfamiliar tall grass-like plant called ‘Teosinte’. Larger and fuller kernels were selected for in order to allow the crop to be a more effective food source. 2. The banana plant is a hybrid and was produced as a result of the cross breeding of two wild South Asian plants species called the Musa acuminata and Musa balbisiana. The hybridized banana plant was unexpectedly tasty, seedless, was a bright yellow colour and maintained an amusing shape. 3. Cattle have been selectively bred so that they have a high muscle to bone ratio, grow and gain weight rapidly. Not only are cattle selectively bred for their meat but also for their milk. Farmers will often breed together cattle that produce large amount of milk with high fat and protein content as well as delivering milk rapidly. 4. Different breeds of chickens are bred with various characteristics, for example, the egg-laying chickens are fed special high-calcium diets so they can make egg shells. These chickens lay around 30 eggs a year. Chickens that are used for meat are bred to grow quickly and have large leg and breast muscles. Selective Breeding Advantages Produces high-yielding strains of crops and animals which means they can be sold for a lower price therefore food becomes more affordable. This leads to a raised standard of living. Can be used to produce animals and plants that have increased resistance to disease. This means farmers have to use fewer drugs and pesticides so their money is saved. Animals and plants could be bred to have increased tolerance of bad conditions where other strain cannot survive on, such as plants that grow in poor soil or on polluted ground. Disadvantages Can cause health problems, for example, dairy cows are often lame and have a short life expectancy because of the extra strain put on their bodies due to making and carrying loads of milk. Another example is the breathing problems experience by selectively bred bulldogs. Reduces genetic diversity, which results in an increased spread of genetic disease and increased susceptibility to new diseases because of the lack of alleles in the population. There are several ethical implications that need to be considered when deciding to selectively breed domesticated animals. One may argue that selective breeding is the human interference with nature therefore is wrong because humans do not have the right to develop new varieties of species because variation will take place naturally as it has been done for the past millions of years. Many people may argue that the wellbeing of humans is more important than the welfare of animals therefore as long as selectively breeding animals raises standard of living and produces enough food to feed people, then it should be an acceptable process. However, one may argue against this and suggest that it is hard to balance between increased yield and animal welfare. Processes like selective breeding put pressure on animal welfare because for example, the artificial insemination of cows to double the milk yield per cow has put strain on a cow’s udder that it has led to mastitis (inflammation of the udder), lameness and infertility. Selective breeding leads to variety in animals with a narrower range of alleles therefore genetic diversity is reduced. This may lead to some undesired alleles to be completely lost forever, which may be useful to animals or mankind in the future. This process may lead one to argue that because the desired alleles of animals are selected, domesticated animals are valued for their usefulness to humans more than anything else, for example, a farmer who selectively breeds a cow to produce more meat may value the cow because it has the potential to raise his profits. There is also the question as to what features should be selected when selectively breeding and which person decides. One may argue that because selectively breeding farm animals benefit humans, then the benefit of selectively breeding pets should make the process of selectively breeding pets acceptable. It is questionable whether features of cats, dogs, rabbits and other pets should have selected alleles only to make them look more fashionable or desirable to their owner.