Thursday 17th September
18.0021.00
Registration & Get-together at the Museum of Ancient Art at Aarhus University
Update your insight into ancient Mediterranean culture by the small quiz we have prepared for you.
Social programme.
Friday, 18th September
From
08.00
Registration
08.3008.45
Welcome and opening remarks
Plenary lectures introduced by Jens Leipziger, Aarhus University
08.4509.15
Plenary and Public Lecture 1 Multimodular Optogenetics, Peter Hegemann, Biological Institute,
Experimental Biophysics, Humboldt Universität zu Berlin, Germany
09.1509.45
Plenary and Public Lecture 2 Importance of mitochondrial adaptations to exercise training
and performance, Carsten Lundby, Institute of Physiology, University of Zürich, Switzerland
09.4511.15
Coffee, posters and exhibitors
SESSION 1
11.1512.45
To pee or not to be
Chairmen Helle Prætorius Aarhus University, Robert Fenton Aarhus University
11.1511.45
Novel principles of renal K+ excretion, Larry Palmer, Dept. Physiology and Biophysics, Cornell
University, New York, USA
11.4512.05
Regulation of NCC activity in renal K+ homeostatic response, Ewout Hoorn, Dept. Internal
Medicine, Erasmus Medical Center Rotterdam, The Netherlands
12.0512.25
The nature and regulation of flow-stimulated renal K+ excretion, Casper K Larsen, Dept.
Biomedicine, Aarhus University, Denmark
12.2512.35
Free communication 1: Is preeclampsia a variant of Liddles syndrome with enhanced
activity of the epithelial sodium channel in the kidneys? Lise Hald Nielsen, Department of
Obstetrics and Gynecology, Aarhus University Hospital, Denmark
12.3512.45
Free communication 2: A novel mutation affecting the arginine-137 residue of AVPR2 in
male dizygous twins leads to congenital nephrogenic diabetes insipidus and attenuated
urine exosome aquaporin-2, Gitte Ryge Hinrichs, Department of Cardiovascular and Renal
Research, University of Southern Denmark, Odense
SESSION 2
11.1512.45
The hot soup
Chairmen Eeva Moilanen, Tampere University,
11.1511.45
Novel signal pathways in inflammation, Eeva Moilanen, The Immunopharmacology Research
Group, Tampere University, Finland
11.4512.05
The role of TRPA1 in pain and inflammation, Edward Högestatt, Dept. Laboratory Medicine,
Lund University, Sweden
12.0512.25
Inflammation as a therapeutic target in stroke, Stuart Allan, Faculty of Life Sciences,
University of Manchester, UK
12.25-
Free communication 1: Impaired Cyclooxygenase-2 Expression leads to aggravated renal
fibrosis in response to unilateral ureteral obstruction in Mice, Signe Tofteng, Dept. of
Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark
12.35
12.3512.45
12.45
14.15
Free communication 2: Deficiency of Microsomal Prostaglandin E Synthase-1 Exacerbates
Renal Fibrosis and inflammation in mice with unilateral ureteral obstruction, R. Luo, Inst.
of Hypertension, Sun Yat-sen University, Guangzhou, China
Lunch
SESSION 3
14.1515.45
Painful news
Chairmen Jens Schouenborg, Lund University, Axel Forman Aarhus University
14.1514.45
A translational animal model of perceived pain magnitude using novel cortically
implanted neural interfaces, Jens Schouenborg, Dept. Experimental Medical Science, Lund
University, Sweden
14.4515.05
Visceral pain: basic, translational and clinical perspectives, Asbjørn M Drewes, Dept. Clinical
Medicine, Aalborg University Hospital, Denmark
15.05-
Intrinsic cold and heat sensitivity of the nocisensor TRPA1, Peter Zygmunt, Div. Clinical
15.25
15.2515.35
15.3515.45
Chemistry and Pharmacology, Lund University, Sweden
Free communication 1: Aerobic exercise reduces pallesthesia and myofascial pain in man,
Dejan Ristic, Dept. of Health Science & Technology, Aalborg University, Denmark
Free communication 2: Changes of nervous conduction in transgenic mice with a changed
metabolism of nerve fibres, P. Dibaj, Max-Planck-Institute of Experimental Medicine, Göttingen
Germany
SESSION 4
14.1515.45
The broken heart
Chairmen Vladimir Matchkov, Aarhus University, Bill Louch, Olso University
14.1514.40
Physiology of hibernation as an angle to understand heart failure, Ole Frøbert, Department
of Cardiology, Örebro University, Sweden
14.4015.05
The Pathophysiology of the broken heart, Elmir Omerovic, Institute of Medicine, University of
Göthenborg, Sweden
15.0515.30
Unmet Needs in treatment of heart failure, Finn Olav Levy, Department of Pharmacology,
University of Oslo, Norway
15.3015.40
Free communication 1: Circadian Rhythms in Cardiac Electrophysiology, Lisa A. Gottlieb,
Dept. of Biomedical Sciences, University of Copenhagen, Denmark
15.4015.50
Free communication 2: BIN1 regulates t-tubule growth during development and
disease, David Lipsett, Inst. For Experimental Medical Research, Oslo University Hospital, Norway
15.50
Posters, exhibitions – wine and snacks
17.45
Bus to City Hall
18.00
Welcome reception in City Hall
Social programme.
Saturday, 19th September
Plenary lectures introduced by Karl Erik Andersson, Aarhus University
8.30-
Plenary and Public Lecture 3 Physiology of ejaculation, Francois A Giuliano, Dept. Physical
9.00
Medicine and Rehabilitation, Paris West Medical University, Orsay, France
9.0009.30
Plenary and Public Lecture 4 The senescent endothelium, Paul M Vanhoutte, Dept.
Pharmacology & Pharmacy, The University of Hong Kong, China
09.3010.30
Coffee, posters and exhibitors
SESSION 5
10.3012.00
Building body parts
Chairmen Karl-Dietrich Sievert, University of Lübeck, Daniella Grimm, Aarhus University
10.3011.00
New for Old - Addressing Bladder and Bowel Function with Tissue Engineering and
Regenerative Medicine, Karl-Dietrich Sievert, Dept.Urology, University of Lübeck, Germany
11.0011.20
Scaffold-free tissue engineering under microgravity conditions, Daniela Grimm, Dept.
Biomedicine, Aarhus University, Denmark
11.2011.40
Regenerating Organs and Tissues: from Bench to Bedside, May Griffith, Dept. Clinical and
Experimental Medicine, Linköping University, Sweden
11.40Free communication 1:
11.50
11.5012.00
Free communication 2: High salt diet results in a hypertonic skin microenvironment, Elham
Nikpey, Dept. Biomedicine, University of Bergen, Norway
10.3012.00
SESSION 6
Acid neighbors (co-sponsored with Physiological Society)
Chairmen Richard Vaughan-Jones, Oxford University, Jeppe Prætorius, Aarhus University
10.3011.00
Carbonic anhydrase 7: Neuronal pH regulatory protein with morphogenic functions, Eva
Ruusuvuori, Neuroscience Center, Helsinki University, Finland
11.0011.20
Pathways for trafficking acid in multi-cellular cancer cell growths, Pawel Swietach, Dept.
Physiology, Dept. Anatomy and Genetics, Oxford University, UK
11.2011.40
Sensing and transport of HCO3- in the vascular wall, Ebbe Bødtkjer, Dept. Biomedicine,
Aarhus University, Denmark
11.40-
Free communication 1: Extracellular acidosis inhibits lymphatic vessel contractility, Anders
Lerche Møller, Dept. of Biomedicine, Aarhus University
11.50
11.50Free communication 2:
12.00
10.3012.00
SESSION 7
Novel aspects of genomics in physiology and pharmacology
Chairmen Lise Lotte Hansen, Aarhus University;
10.3011.00
Sequencing and epigenetics to unravel the pathophysiology of cancer, Jörg Tost, the
National Genotyping Center, Evry, France
11.0011.20
The use of genetic variation to predict age-related diseases as cardiovascular disease
and dementia, Ruth Frikke-Schmidt, Copenhagen University Hospital, Denmark
11.2011.40
Pharmacogenetics of metformin, Mette Marie H. Christensen, University of Southern Denmark,
Odense, Denmark
11.40-
Free communication 1: Mutations in the human SLC34A2 gene – characterization and effect
on phosphate transport in Pulmonary Alveolar Microlithiasis, Åsa Jönsson, Dept. of
Biomedicine, Aarhus University
11.50
11.5012.00
Free communication 2: Treatment with metformin improves endothelial function in aortic
tissue and microvascular endothelial cells subjected to diabetic hyperglycaemic
conditions, Chris Triggle, Pharmacology, Weill Cornell Medical College in Qatar
12.0013.30
Lunch
12.15
General Assembly
SESSION 8
13.3015.00
The devil is in the detail
(co-sponsored with British Pharmacological Society)
Chairmen Nanna MacAulay, Copenhagen University, Bryndis Birnir, Upssala University
13.3014.00
Kv7.4 and Kv7.5 guardians of smooth muscle excitability, Iain Greenwood, Institute of
Cardiovascular & Cell Sciences, St. George’s, University of London, UK
14.0014.20
Functional roles of Kv7 channels in the hippocampal-entorhinal memory system, Johan
Frederik Storm, Dept. Physiology, University of Oslo, Norway
14.20-
Role of Kv7.1 in insulin secretion, Nicole Schmitt, Dept. Biomedicine, Copenhagen University,
14.40
Denmark
14.4014.50
Free communication 1: Altered stiffness in coronary arteries and effect of pirfernidone on
endothelium-dependent vasodilatation in type 2 diabetic (db/db) mice, Lilliana Beck, Dept.
of Biomedicine, AU, Aarhus
14.5015.00
Free communication 2: Inhibition of Kv7 channels protects against myocardial ischemia
and reperfusion injury, Elise Røge Hedegaard, Dept. of Biomedicine, AU
SESSION 9
13.3015.00
Cold news
Chairmen Tobias Wang, Aarhus University and Angela Fago, Aarhus University
13.3014.00
Central nervous system control of hibernation reveals opportunities for human
hibernation, Kelly Drew, Institute of Arctic Biology, University of Alaska Fairbanks, USA
14.0014.20
Are you dead, just because you are cold? Benedict Kjærgaard, Biomedical Research
Laboratory, Region Nordjylland, Denmark
14.2014.40
Power napping extreme - hibernation in primates, Kathrin Dausmann, Animal Ecology and
Conservation, Biocentre Grindel, University of Hamburg, Germany
14.4014.50
14.5015.00
15.0015.30
Free communication 1: Regulation of hemoglobin oxygen affinity in hibernating
animals, Angela Fago, Dept. of Bioscience, Aarhus University
Free communication 2: Pump those ions or you’ll wake up dead: Key differences in how
chilling affects tropical and temperate Drosophila species, Heath A MacMillan, Dept. of
Bioscience, Aarhus University
Coffee
SESSION 10
15.3017.00
Lymphatic vessels – the ugly duckling of the vascular system
Chairmen, Helge Wiig, University of Bergen, Donna B Bødtkjer, Aarhus University
15.3016.00
Lymphatic pump and valve dysfunction in genetic models of lymphatic disease Michael J
Davis, Dept. Medical Pharmacology & Physiology, University of Missouri, USA
16.00-
A new role of the interstitium and lymphatics in the development of hypertension Helge
16.20
Wiig, Dept. Biomedicine, University of Bergen, Norway
16.2016.40
Ion channels and lymphatic vessel function Donna B Bødtkjer, Dept. Biomedicine, Aarhus
University, Denmark
16.4016.50
Free communication 1: A functional role for pacemaking HCN channels in lymphatics? Jens
Majgaard, Dept. of Biomedicine, AU
16.50Free communication 2:
17.00
SESSION 11
15.3017.00
The marathon man
Chairmen: Ole Bækgaard Nielsen, Aarhus University, Ylva Helsten, Copenhagen
University
15.3016.00
Oxygen uptake dynamics during exercise, Andrew M. Jones, Sport and Health Sciences,
College of Life and Environmental Sciences, University of Exeter, UK
16.0016.20
Maximal heart rate and cardiovascular capacity in humans, Dr. Stefan P. Mortensen, Dept.
Molecular Medicine, University of Southern Denmark
16.2016.40
Blood flow restricted and traditional resistance training produce equal muscle
hypertrophy when performed to fatigue, Frank de Paoli, Dept. Biomedicine, Aarhus University
16.4016.50
Free communication 1: Skeletal muscle dysfunction in the db/db mouse model of type 2
diabetes, Jeppe Seamus Bayley, Dept. Biomedicine, Aarhus University
16.5017.00
Free communication 2: Regional differences in signaling pathways activity and gene
expression levels in rat gastrocnemius muscle after a series of intense
contractions, Anna Borzykh, SRC RF, Inst. For Biomedical Problems, Moscow, Russia
Plenary lecture introduced by Jens Leipziger, Aarhus University
17.00
-17.40
Plenary and Public Lecture 5 Purinergic signaling in the lung: from bench to bedside and
back again, Marco Idzko, University Hospital, Freiburg, Germany
18.00
Gala dinner
See the social programme
Sunday, 20th September
Plenary lecture introduced by Tomi Taira, Helsinki University
9.009.30
Plenary and Public Lecture 6 The nightlife of the brain, Maiken Nedergaard, Center of Basic and
Translational Neuroscience, Copenhagen University, Denmark
SESSION 12
9.4011.10
High blood pressure becomes less essential
Chairmen: Pernille B. Lærkegaard Hansen, University of Southern Denmark, Peter
Rossing, Steno Diabetes Center, Copenhagen
09.4010.10
Defects of plasma membrane proteins: The first step to hyperaldosteronism? Richard
Warth, Medical Cell Biology, Institute of Physiology Regensburg, Germany
10.1010.30
Primary aldosteronism - from genetic abnormalities to pathophysiological models, MariaChristina Zennaro, INSERM, U970, Paris Cardiovascular Research Center – PARCC Paris, France
10.3010.50
Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal
hypertension, Hanne Poulsen, Dept. Biomedicine, Aarhus University, Denmark
10.5011.00
Free communication 1: Angiotensin II AT1-receptor blockade using Losartan does not
impair renal oxygenation following hemorrhage, Jacqueline Melville, Dept. of medical Cell
Biology, Uppsala University, Sweden
11.0011.10
Free communication 2: Deficiency of the T-type calcium channel Cav3.1 attenuates plasma
aldosterone and cardiac hypertrophy despite similar AngII-induced hypertension, Anne
Daugaard Thuesen, Inst. of Molecular Medicine, University of Southern Denmark, Odense,
Denmark
SESSION 13
9.4011.10
Urgent matters
Chairmen Chris Fry, University of Bristol, Karl Erik Andersson, University of Aarhus
9.4010.10
The role of the mucosa in normal and abnormal bladder function, Chris Fry, School of
Physiology and Pharmacology, University of Bristol, UK
10.1010.30
MicroRNAs in bladder outlet obstruction: relationship to matrix remodelling and growth,
Karl Swärd, Dept. Physiology, Lund University, Sweden
10.3010.50
Inhibitory effects of urothelium-related factors, including PGD2, in guinea-pig urinary
bladder, Lars E Gustafsson, Dept. Physiology and Pharmacology, Karolinska Institutet, Stockholm,
Sweden
10.5011.00
11.0011.10
11.1011.30
Free communication 1: Role of SK3 channels in rectile function in mice, Simon ComermaSteffensen, Dept. of Biomedicine, Aarhus University
Free communication 2: Interstitial Cajal-like cells in the female reproductive tract, Sergey
Machado-Abakumov, Dept. of Biomedicine, Aarhus University
Coffee and exhibitors
SESSION 14
11.3013.00
Top flow
Chairmen
11.3012.00
Capillary flow patterns and brain oxygenation, Sava Sakadzic, Harvard Medical School,
Boston, USA
12.0012.20
Capillary pericytes in health and disease, Catherine Hall, Sussex Neuroscience, University of
Sussex and University College London, UK
12.2012.40
Capillary flow patterns and brain oxygenation, Leif Østergaard, Dept. Neuroradiology, Aarhus
University, Denmark
12.4012.50
12.5013.00
Free communication 1: The α-2 isoform of Na,K-ATPase Modulates Vascular Tone via
Activation of Src-kinase (Src) Signaling Pathway: a Lesson from Mouse model for
Familial Hemiplegic Migraine Type 2 (FHM2), Vladimir Matchkov, Dept. of Biomedicine, Aarhus
University
Free communication 2: Changes in vasoreactivity following middle cerebral artery
occlusion,André Erdling, Experimental Vascular Research, Lund University, Sweden
SESSION 15
11.3013.00
Moving Lipids
Chairmen Karin Lykke-Hartmann, University of Aarhus, Jens Peter Andersen, University
of Aarhus
11.3012.00
ATP-dependent Lipid Pumps: Linking Lipid Transport to Cell Function and Disease, Robert
S. Molday, Dept. Biochemistry and Molecular Biology, University of British Columbia, Vancouver,
BC, Canada
12.0012.25
Lipid pumps and ion pumps: how different are they, Jens P. Andersen, Dept. Biomedicine,
Aarhus University, Denmark
12.2512.50
The role of lipid flippases in bile formation, Coen Paulusma, Tytgat Institute for Liver and
Intestinal Research, Academic Medical Center, Amsterdam, Netherlands
12.50-
Free communication 1:
13.00
Free communication 2:
13.0013.30
Lunch
13.3015.00
SESSION 16
Mind your molecules
13.3014.00
Cliff Kentros, Trondheim, Norway
14.0014.25
The Arc of synaptic memory, Clive Bramham, Dept. Biomedicine, University of Bergen
14.2514.50
Tomas Bjorklund, Dept. Experimental Medical Science, Lund University.
14.5015.00
Free communication: Mapping the dualistic profile of an allosteric AMPA receptor
modulator-studies on recombinant receptors, mouse hippocampal synapses and crystal
structures, Mai Marie Holm, Dept. of Biomedicine, Aarhus University
SESSION 17
13.3015.00
Into thin blood
Chairmen Anne Mette Hvas, Aarhus University, Rickard Malmström, Karolinska
Institutet, Stockholm
13.3014.00
New mechanisms and targets for antiplatelet and anticoagulation therapy, Robert
Flaumenhaft, Harvard Medical School, Boston, USA
14.0014.20
Novel oral anticoagulants and the clinical pharmacological/therapeutic aspect of
therapeutic drug monitoring, Rickard Malmström, Dept. Medicine Solna, Karolinska Institutet,
Stockholm
14.20-
Aspirin in coronary artery disease: potential causes of reduced antiplatelet effect, Anne-
14.40
Mette Hvas, Aarhus University
14.40-
Free communication 1: Dual activation of the bile acid nuclear receptor FXR and G-proteincoupled receptor TGR5 attenuates lithium-induced nephrogenic diabetes
insipidus, Weidong Wang, Sun Yat-sen University, Guangzhou, China
14.50
14.50-
Free communication 2:
15.00
15.00
End of Meeting