Munich - March 13, 2015 Press Release GABO:mi collaborates in regenerative medicine project funded by the European Commission’s Horizon 2020 programme March 13, 2015 – The project TREGeneration comprises a European consortium that recently obtained funding from the European Commission under the Horizon 2020 programme. The consortium carries out a clinical research project for the treatment of Graft versus Host Disease, a serious complication following bone marrow transplantation. A total of 6 million euros was awarded to the consortium to perform a 5-year research project which includes a set of five parallel clinical trials. Graft versus host disease can be a severe condition occurring when the donor’s immune cells "attack" the tissues of the patient (skin, internal organs and mucosa). This disease occurs in about 30 to 50% of patients undergoing bone marrow transplantation. TREGeneration aims to test a cell-based therapeutic approach, expected to result in fewer side effects than the pharmacological strategies currently available. In each trial, patients will be treated with a particular blood cell population obtained from the original bone marrow donor. These cells have the capacity to suppress (regulatory T cells). These are Phase I/II clinical trials that aim to identify the safe dose to be administered and to generate preliminary efficacy data. The Consortium The TREGeneration consortium is led by João Lacerda’s team at Instituto de Medicina Molecular in Lisbon, Portugal. GABO:mi, based in Munich, is in charge of the project management. The clinical trials will be independently run by each center: Hospital de Santa Maria in Lisbon, Portugal; Universitaetsklinik in Regensburg, Germany; Laboratory of Cell and Gene Therapy in Liège, Belgium; University Hospital S. Orsola-Malpighi in Bologna, Italy. The consortium further includes a team at the Max Planck Institute for Molecular Genetics and Alacris Theranostics GmbH. Both are from Berlin, Germany. The data generated by the different clinical trials will be integrated by the statistical analysis performed by the Department of Biostatistics, University of Liverpool, UK. GABO:mi Gesellschaft für Ablauforganisation :milliarium mbH & Co. KG Oskar-von-Miller-Ring 29 – 80333 Munich – Germany – phone +49-89-288104-0 – www.gabo-mi.com Page 1 of 2 Munich - March 13, 2015 Press Release About Horizon 2020 Programme Horizon 2020 is the biggest EU Research and Innovation programme ever with nearly €80 billion of funding available over 7 years (2014 to 2020). It promises more breakthroughs, discoveries and world-firsts by taking great ideas from the lab to the market. About GABO:mi GABO:mi is a project management company specialised in the management of EU-funded research projects. Since it was founded in 2005, GABO:mi has continually expanded its extensive expertise with diverse EU funding instruments. GABO:mi has managed 40+ medium- and large-scale collaborative projects funded by the European Commission to date. Our project managers have vast and valuable experience in the management of EU-funded projects. They are familiar with the underlying structures of international collaborative research projects and their governing principles. Additionally, they are always up-to-date with regard to the current regulations of the European Commission and its agencies. Project Logo Press Contact GABO:mi Gesellschaft für Ablauforganisation :milliarium mbH & Co. KG Dr. Sibylle Freitag Phone: +49-89 288104-18 E-Mail: sibylle.freitag@gabo-mi.com www.gabo-mi.com Social Media Twitter http://bit.ly/GABOmi_Twitter GABO:mi Gesellschaft für Ablauforganisation :milliarium mbH & Co. KG Oskar-von-Miller-Ring 29 – 80333 Munich – Germany – phone +49-89-288104-0 – www.gabo-mi.com Page 2 of 2