Funded MURI Projects for Summer 2014 Exploring Conformational Changes Associated with Substrate/inhibitor Binding to the Adrenaline Synthesizing Enzyme, PNMT Primary Mentor: Michael J. McLeish, Associate Professor, Departments of Chemistry and Chemical Biology, School of Science, mcleish@iupui.edu Co-mentor: Horia Petrache, Associate Professor, Department of Physics, School of Science, hpetrach@iupui.edu Co-mentor: Bruce D. Ray, Associate Scientist, Department of Physics, School of Science, bray@iupui.edu Student Majors Requested: Chemistry, Biology, Physics, Engineering Skills Expected From Students: Basic chemistry, biology, physics, or engineering laboratory experience. Number of Students: Six Proposal The Effectiveness of Motivational Interviewing to Improve Adherence to Glaucoma Treatment in Patients of African Descent Primary Mentor: Lyne Racette, Assistant Professor, Department of Ophthalmology, School of Medicine, lracette@iupui.edu Co-mentor: Silvia Bigatti, Associate Professor, Department of Social and Behavioral Sciences, Fairbanks School of Public Health, sbigatti@iu.edu Student Majors Requested: Biology and Health Sciences Skills Expected From Students: Skills expected from students at the start of the project include: Strong writing, analytical and communications skills; familiarity with basic research design and statistical analysis; proficiency with data management; familiarity with commonly used programs (e.g. Excel); persistence; detail-oriented. Number of Students: Four Proposal Drug-Perturbation Pathway Modeling and its Application to Bladder Cancer Primary Mentor: Jake Chen, Associate Professor, Department of BioHealth Informatics, School of Informatics and Computing, jakechen@iupui.edu Co-mentor: Xiaogang Wu, Assistant Scientist, Department of BioHealth Informatics, School of Informatics and Computing, wu33@iupui.edu Student Majors Requested: Biology, Chemistry, Computer Science, Mathematics, Engineering, Clinical Pharmacology Skills Expected From Students: Computer Science- Excel, sql, matlab, linux, php, java, Biology-molecular biology, neurology, Math- statistics, graph theory; Clinical Pharmacology; pharmacogenomics Number of Students: Four Proposal Activation of Osteoclasts by Nicotine-Treated Periodontal Pathogens Primary Mentor: Richard L. Gregory, Professor, Departments of Oral Biology/Microbiology, Schools of Dentistry and Medicine, rgregory@iu.edu Co-mentor: L. Jack Windsor, Associate Professor, Departments of Oral Biology/Cell Biology, School of Dentistry, ljwindso@iu.edu Co-mentor: Fengyu Song, Assistant Professor, Departments of Oral Biology/Regenerative Biology, Schools of Dentistry and Science, fesong@iu.edu Co-mentor: Angela Bruzzaniti, Assistant Professor, Departments of Oral Biology/Bone Biology, Schools of Dentistry and Medicine, abruzzan@iu.edu Student Majors Requested: Biology, Chemistry, Pre-Dentistry or Pre-Medicine Skills Expected From Students: Good analytical skills, basic understanding of chemistry and/or biology, persistence and strong attention to detail. Number of Students: Six Proposal Summer Health Academy for Latino Youth: Intervention Planning, Implementation, and Evaluation Primary Mentor: Silvia Bigatti, Associate Professor, Department of Social and Behavioral Sciences, Fairbanks School of Public Health, sbigatti@iu.edu Co-mentor: Monica Medina, Clinical Lecturer; Associate Director for Community Partnerships, Center for Urban and Multicultural Education, mmedina@iupui.edu Co-mentor: Katrina Conrad, Community Research Coordinator, Fairbanks School of Public Health khaitsma@indiana.edu Student Majors Requested: Public Health; Tourism, Convention and Event Management; Social Work, Education, Psychology, Sociology, Rehabilitation Sciences Skills Expected From Students: Student investigators will be involved in the intervention design (summer camp for Latino youth) and will also serve as mentors to camp participants. Student investigators with prior leadership experience (in any extracurricular activity for example) will be preferred. Also preferred will be students that demonstrate cultural competency and professionalism. Spanish language ability is preferred. Because we hope these students will serve as mentors during the camp experience, we would prefer students who are themselves Latinos. Number of Students: Six Proposal Meta-Analysis of Podcasting in Higher Education Primary Mentor: Eugenia Fernandez, Associate Professor and Chair, Department of Computer and Information Technology, School of Engineering and Technology, efernand@iupui.edu Co-mentor: Wanda Worley, Associate Dean for Academic Affairs and Undergraduate Programs; Associate Professor of Technical Communication, School of Engineering and Technology, wworley@iupui.edu Student Majors Requested: English, Education, Business Communication (any and all majors welcome) Skills Expected From Students: Good communication skills (written and oral), good work ethic, ability to analyze and synthesize data. Number of Students: Four Proposal Effect of Nano-grating Patterned Substrate on Vascular Cell Behavior in Response to Shear Flow and Strain Primary Mentor: Julie Ji, Associate Professor, Department of Biomedical Engineering, School of Engineering and Technology, jji@iupui.edu Co-mentor: Jong Eun Ryu, Assistant Professor, Department of Mechanical Engineering, School of Engineering and Technology, jeryu@iupui.edu Co-mentor: Hazim El-Mounayri, Associate Professor, Department of Mechanical Engineering, School of Engineering and Technology, helmouna@iupui.edu Co-mentor: Omar El-Mounayri, Post-Doctoral Fellow, Department of Cardiology, McEwen Center for Regenerative Medicine, University of Toronto, Ontario, Canada, oelmouna@yahoo.com Student Majors Requested: Mechanical Engineering, Biomedical Engineering, Chemistry or Biology Skills Expected From Students: For biomedical engineering students: understanding of cell and molecular biology, human physiology, cellular biomechanics, ECM, and biomaterials. For mechanical engineering students: nano-grating fabrication, chemistry lab skills, modeling, design, (preferably) manufacturing, programming (using Matlab), Labview. For chemistry student: design of chemistry reaction, surface modification, polymer chemistry and biomaterial. For biology students: molecular cell biology with basic lab skills, in cell culture, real time polymerase chain reaction (qPCR), protein extraction, Western Blotting, cell viability. Number of Students: Five Proposal Solid Electrolyte and Composite Electrode Materials for Lithium-ion Battery Primary Mentor: Jing Zhang, Assistant Professor, Department of Mechanical Engineering, School of Engineering and Technology, jz29@iupui.edu Co-mentor: Yeon Gil Jung, Visiting Professor, Department of Materials Science and Engineering, Changwon National University, South Korea; jung45@iupui.edu Co-mentor: Linmin Wu, Graduate Research Assistant, Department of Mechanical Engineering, School of Engineering and Technology, lw54@umail.iu.edu Student Majors Requested: Mechanical Engineering, Chemistry, Electrical Engineering Skills Expected From Students: Materials synthesis; Mechanical engineering design and fabrication; Electrochemical Analysis Number of Students: Five Proposal Summary (Please contact Dr. Zhang for additional information)