how cells multiply, madison 2011

How do cells multiply?
Cell/Developmental Biology Group
The Cyclers
Background of the Class
(for SI participants only)
• Course: Introduction to Biology (Majors)
• Class Size: 55+ students
• Module: Cell Biology, two-week (6 lectures)
teachable unit on cell cycle
• First class of the unit
• What do students know already?
Nucleotides, DNA, chromosomes, and organelles
• Students will learn about the cell cycle.
The Cell Cycle
Who cares?
How does cell division relate to human health?
Down Syndrome:
1 in 800 babies
born in US
23% of all deaths in US in
2007 resulted from cancer
What will we learn today?
• We will be able to explain why each of the
phases of the cell cycle occur in the order that
they do
How will we learn how cells divide?
In small groups (two groups per table) we will:
• Brainstorm to determine what the most basic
events the cell must undergo to achieve division
• Generate a common list of events
• Determine the order in which the events occur
Brainstorm Question…
Come up with a list of actions or
events that an animal cell must
undergo to achieve division.
2 minutes
Work in your groups to arrange the notes in
the order that would make the cell divide…
(3 min)
Where do we go from here?
• We will be able to sequence the events of the cell
cycle and explain why each of the phases occur in the
order that they do
Rest of Teachable Unit
• To know what checkpoints and their functions are
• To understand the functions of cyclins and CDKs
(e.g. concentrations at different stages of cell cycle,
different specificities, activities regulated by other
• Mitosis: what is it and what is the outcome?
• What actions occur to move the chromosomes and
divide the two cells?
• To understand diseases related to the cell cycle
relate to diseases