PerStat Medical Systems, Inc. is proud to announce a new Autologous physiologic glue, which will assist the surgeon to … Gain hemostasis Seal wound surfaces Potentially increase rate of wound healing Platelet Gel: Surgeons are all too familiar with the fact that … Postoperative loss of critical body fluids can defeat an otherwise successful surgical outcome Serous fluid exudates can slow the healing of wounds and serve as a culture medium for infection Highly vascular tissue, once cut, will bleed even through the eschar of electrocautery, and continue to produce exudates for long periods, after frank blood loss ceases Cryoprecipitate and fibrin glue is costly, difficult to obtain, and may be a source of HIV transmission This autologous procedure … Is safe: No opportunity for clerical error No need for predonation No fear of viral transmission (HIV), hepatitis, etc.) Is reliable and immediately available: Rapid setup time (needs an IV of 16 Ga or larger) Rapid processing time Is efficacious: Healing time improved due to control of bleeding and potential of increased wound healing rate Is performed once the patient is under anesthesia on the OR table Takes only a few minutes to prepare approximately 100 cc of platelet gel (glue) Can be used in conjunction with perfusion, or autotransfusion procedures, improving cost reduction Faster Healing, Faster Recovery, Cost Reduction Occasionally, a truly revolutionary concept enters surgery … PerStat Medical Systems, Inc. 11514 Orchard Mountain Dr. Houston, TX 77059 T: 281-744-0323 F: 281-486-2691 b.parrish@perstat.com www.perstat.com Potential Clinical Applications of Use Aspects Cryoprecipitate Concentrated PRP Surgical Field of Use Type of Application Product Fibrin Glue Platelet Gel Cardiovascular - Sealing of vascular anastomoses, prostheses, patches, and epicardial bleeding - Mediastinal gel application - Control of bleeding with vascular graft material Function Strong Adhesive Tissue Sealant Hemostatic Agent Tissue Sealant Moderate Strength Adhesive Source Blood Bank Pooled Blood Donors Patient Predeposit Operating Room N/A Patient in OR Volume 10-12 ml per Unit Mixture Ratio (Product Activator) 1:1 ~ 40 ml/per pass with 125 bowl ~ 100 ml/per pass with 225 bowl 5:1 to 8:1 Days Days N/A Minutes >$450/unit >$950/unit Thoracic Trauma Transplant Urology Plastic Repair Head and Neck; Ear and Throat Oral Central Nervous System, Nerve Repair Gastrointestinal Orthopedic - Control of pneumothorax or pulmonary air leak - Realignment of tracheal transaction injury - Treatment of bronchopleural fistula - Repair of splenic injury - Repair of liver laceration - Transplant of partial hepatectomy specimen - Repair of renal laceration - Hemostasis and sealant for partial nepherectomy - Parenchymal sealant for wound repair - Hemostasis and sealant for prostatectomy - Fixation of skin or scalp degloving - Fixation of skin grafts and flaps - Blepharoplasty, brow and face lifts - Decubitus Ulcer treatment - Seroma prevention in radical neck dissection - Tympanic membrane patch - Sinus procedures - Flap and graft procedures - Adjuvant to repair of dural injury; repair of peripheral nerve injury - Repair common bile duct injury; adjuvant to repair of bowel anastomoses (possible) - Repair of osteochondral fracture of Achilles tendon - Control of seroma/post-operative drainage with Total Hip/Knee replacement Homologous Autologous Time Required Homologous Autologous Cost Homologous Autologous Fibrinogen Content 20-200 mg/ml N/A W/ Sequestra ~ $ 0 W/ Salvage ~ $100 Dedicated ~ $200 2-4 mg/ml Platelet Content of Product None 2.5-3.0 x 1018/ml Possible Wound Healing and Tissue Growth Factors No Yes Yes Yes Yes Yes No No No No No Dangers from Allosensitizations Allergy/Anaphylaxis Clerical Error Storage Error Disease Transmission Yes For more information concerning platelet gel, please visit our website, at: www.perstat.com