Graduate Curriculum Committee Course Proposal Form
for Courses Numbered 5000 and Higher
Note: Before completing this form, please carefully read the accompanying instructions.
Submission guidelines are posted to the GCC Web site: http://www.ecu.edu/cs-acad/gcc/index.cfm
1. Course prefix and number:
2. Date:
BIOL 6242
1/31/2013
3. Requested action:
X
New Course
Revision of Active Course
X
x
Revision & Unbanking of a Banked Course
Renumbering of an Existing Course from
from
to
# 5810
Required
x
# 6242
Elective
4. Method(s) of delivery (check all boxes that apply for both current/proposed and expected
future delivery methods within the next three years):
Current or
Proposed Delivery
Method(s):
X
On-campus (face to face)
Expected
Future Delivery
Method(s):
X
Distance Course (face to face off campus)
Online (delivery of 50% or more of the instruction is offered online)
5. Justification. Identify the committee or group (e.g., Graduate faculty of the Department of
English) that conducted the assessment of curriculum and student learning. Explain why the
unit wishes to offer or revise the course. Include specific results from the unit assessment that
led to the development or modification of the course. If applicable, cite any accrediting
agency/ies and reference the specific standard/s.
Following assessment of the biology graduate curriculum the
Biology Department Graduate Committee approved revision of
the current course to rectify a preponderance of undergraduate
enrollment, and to increase the diversity of course offerings for
biology doctoral students. The revised course would be a
requirement for the MS Molecular Biology/Biotechnology
program, and an elective for the MS Biology and IDPBS
programs.
Approved by GCC April 2012; posted summer of 2012
6. Course description exactly as it should appear in the next catalog:
BIOL 6242. Principles of Biochemistry II (3) Formerly BIOL 5810 P:
BIOL 3310, 3311; CHEM 2760, 2763; or consent of instructor. Intermediary
metabolism including the pentose phosphate and Entner-Doudoroff
pathways, glycogen and fatty acid metabolism, biosynthesis of amino
acids, nucleotides, and lipids. DNA replication and repair, RNA synthesis
and processing and protein synthesis and degradation. Signal
transduction and the control of gene expression.
7. If this is a course revision, briefly describe the requested change:
Change from 5000 level to 6000 level course and revised course description
8. Course credit:
Lecture Hours
3
3
Weekly
OR
Per Term
Credit Hours
Lab
Weekly
OR
Per Term
Credit Hours
s.h.
Studio
Weekly
OR
Per Term
Credit Hours
s.h.
Practicum
Weekly
OR
Per Term
Credit Hours
s.h.
Internship
Weekly
OR
Per Term
Credit Hours
s.h.
Other (e.g., independent study) Please explain.
Total Credit Hours
9. Anticipated annual student enrollment:
3
10
10. Changes in degree hours of your programs:
Degree(s)/Program(s)
Changes in Degree Hours
MS Molecular
Biology/Biotechnology
MS Biology
NA
NA
11. Affected degrees or academic programs, other than your programs:
Degree(s)/Program(s)
Changes in Degree Hours
PhD IDPBS
NA
12. Overlapping or duplication with affected units or programs:
Not applicable
X
Documentation of notification to the affected academic degree programs is
attached.
13. Council for Teacher Education (CTE) approval (for courses affecting teacher education):
Not applicable
X
Applicable and CTE has given their approval.
14. University Service-Learning Committee (USLC) approval:
Not applicable
X
Applicable and USLC has given their approval.
Approved by GCC April 2012; posted summer of 2012
s.h.
s.h.
s.h.
15. Statements of support:
a. Staff
X Current staff is adequate
Additional staff is needed (describe needs in the box below):
b. Facilities
X Current facilities are adequate
Additional facilities are needed (describe needs in the box below):
c. Library
X Initial library resources are adequate
Initial resources are needed (in the box below, give a brief explanation and an
estimate for the cost of acquisition of required initial resources):
d. Unit computer resources
X Unit computer resources are adequate
Additional unit computer resources are needed (in the box below, give a brief
explanation and an estimate for the cost of acquisition):
e. ITCS resources
X ITCS resources are not needed
The following ITCS resources are needed (put a check beside each need):
Mainframe computer system
Statistical services
Network connections
Computer lab for students
Software
Approval from the Director of ITCS attached
16. Course information (see: Graduate Curriculum and Program Development Manual for
instructions):
a. Textbook(s) and/or readings: author(s), name, publication date, publisher, and
city/state/country. Include ISBN (when applicable).
Required textbook:
Jeremy M. Berg, John L. Tymoczko, Lubert Stryer. 2012. Biochemistry 7th
Edition. W.H. Freeman and Company, New York, NY. ISBN-10: 1-42922936-5 ISBN-13: 978-1-4292-2936-4
b. Course objectives for the course (student – centered, behavioral focus)
If this is a 5000-level course that is populated by undergraduate and graduate students,
there must be differentiation in the learning objectives expected.
Upon completion of this course, students will be able to:
1. Describe the intermediary pathways for the synthesis of biological
macromolecules: proteins, carbohydrates, lipids, and nucleic
acids.
Approved by GCC April 2012; posted summer of 2012
2. Explain the biochemical basis of many human diseases caused by
errors of intermediary metabolism such as Lesch-Nyan, diabetes,
lysosomal storage diseases and cirrhosis.
3. Describe biochemical signaling pathways and their relation to
normal cellular growth and cancer.
4. Make informed decisions about their nutrition and exercise with
regard to their health and body’s metabolism.
5. Discuss the molecular nature of metabolism process and anticipate
the organism responses under different physiological and
environmental conditions.
6. Perform a comprehensive literature search to gain an
understanding of the multidisciplinary span of biochemistry
research and present the findings on specific topics.
7. Develop a hypothesis-driven research proposal and design
research strategies to investigate a biochemistry research problem
identified by literature search or other initiatives.
c. Course topic outline
The list of topics should reflect the stated objectives.
Pentose Phosphate and Entner-Doudoroff pathways
Glycogen metabolism
Fatty acid metabolism
Protein turnover and amino acid catabolism
Biosynthesis of amino acids
Biosynthesis of nucleotides
Biosynthesis of lipids and steroids
Integration of metabolism
DNA replication and repair
RNA synthesis and processing
Protein synthesis
Control of gene expression
Membrane Proteins
Signal Transduction
Molecular motors
d. List of course assignments, weighting of each assignment, and grading/evaluation system
for determining a grade
There will be 3 midterm exams and a final. There will be 2 quizzes to be taken on
Blackboard and 5 written assignments.
FINAL GRADE: EXAMS 70% (15% for each midterm, 25% for the final)
QUIZZES 5% (2.5% each)
WRITTEN ASSIGNMENTS 25% (5% each)
Grade
A = 90-100%
B = 80-89
C = 70-79
F  69
Approved by GCC April 2012; posted summer of 2012
Approved by GCC April 2012; posted summer of 2012