Online Appendix for the following JACC article
TITLE: Characteristics and Long-Term Outcomes of Percutaneous Revascularization of Unprotected Left Main Coronary Artery
Stenosis in the United States: A Report from the National Cardiovascular Data Registry, 2004 to 2008
AUTHORS: J. Matthew Brennan, MD, MPH, David Dai, PHD, Manesh R. Patel, MD, Sunil V. Rao, MD, Ehrin J. Armstrong, MD,
MSC, John C. Messenger, MD, Jeptha P. Curtis, MD, Kendrick A. Shunk, MD, PHD, Kevin J. Anstrom, PHD, Eric L. Eisenstein,
DBA, William S. Weintraub, MD, Eric D. Peterson, MD, MPH, Pamela S. Douglas, MD, William B. Hillegass, MD, MPH
APPENDIX
Table 1
EuroSCORE
EuroSCORE Definitions
NCDR Variable
Set to
EuroSCORE
Variable
Beta
Age
252
0.0666354
Sex (female)
260
0.3304052
454
0.4931341
452
0.6558917
CLD
Long-term use of bronchodilators or
steroids for lung disease
PAD
One or more of claudication, carotid
occlusion or >50% stenosis, previous or
planned intervention on the abdominal
aorta, limb arteries, or carotids
Neurological
Disease severely affecting ambulation or
dysfunction
day-to-day functioning
Cr >200 micmol/l
N/A
missing 0.841626
440-- impute missing w/ existing multiple
1.002625
imputations code
IE
Patient still on antibiotic treatment for
N/A
no
1.101265
endocarditis at time of surgery
Critical state
Ventricular tachycardia/ventricular
Yes if any of the following are present: 520
fibrillation or aborted sudden death,
(shock), 640 (only if IABP present before
preoperative cardiac massage, preoperative lab visit), 704 (if emergent or salvage), 804
ventilation before anesthetic room,
preoperative inotropes or IABP,
preoperative acute renal failure (anuria or
oliguria <10ml/hr)
(if emergent or salvage)
0.9058132
UA
Rest angina requiring IV nitrates until
812
0.5677075
LV function (poor,
if 656 is present, use 656 first (<30%=poor;
mod:
mod, good)
30-49%=mod; >/=50% is good); if 656 not
0.4191643;
present, us 652 (normal=good,
poor:
abnormal=mod); if 656 & 652 not present,
1.094443
arrival in anesthetic room
set to normal
Recent MI
Myocardial infarction within 90 days
550 (if non-STEMI or STEMI)
pHTN
Systolic pulmonary artery pressure
N/A
0.5460218
missing 0.7676924
>60mmHg
Emergency
Operation before beginning of next
yes if any of the following are present: 520
working day
(shock), 704 (if emergent or salvage), 804
0.7127953
(if emergent or salvage), 812
Other than CABG
N/A
No
0.5420364
Surgery on thoracic
N/A
No
1.159787
N/A
No
1.462009
aorta
Post-infarct septal
rupture
CABG = coronary artery bypass grafting; CLD = chronic lung disease; IE = infective endocarditis; LV = left ventricular; pHTN =
pulmonary hypertension; MI = myocardial infarction; PAD = peripheral artery disease; UA = unstable angina
Table 2
Unadjusted
Study Pop
Total DES BMS
N
No trim
Propensity scores
N
Outcome
N
2,765 2,044 721
2,754 2,033 721
HR
Lower Upper P Value
CL
Death
Adjusted
CL
HR
Lower Upper P Value
CL
CL
0.596 0.520
0.683
<.001
0.838 0.732 0.958
0.010
Death/MI/Revasc 0.710 0.630
0.799
<.001
0.946 0.840 1.064
0.354
0.598 0.521
0.685
<.001
0.840 0.734 0.961
0.011
Death/MI/Revasc 0.712 0.632
0.802
<.001
0.948 0.842 1.067
0.379
0.620 0.540
0.713
<.001
0.786 0.680 0.907
0.001
Death/MI/Revasc 0.713 0.631
0.805
<.001
0.848 0.748 0.961
0.010
0.667 0.576
0.772
<.001
0.773 0.663 0.901
0.001
Death/MI/Revasc 0.721 0.634
0.820
<.001
0.792 0.693 0.906
<.001
Death
trimmed at 0.01 and 0.99
Propensity scores
2,533 1,823 710
Death
trimmed at 0.05 and 0.95
Propensity scores
2,114 1,432 682
Death
trimmed at 0.10 and 0.90
BMS = bare metal stent; CL = confidence limit; DES = drug-eluting stent; HR = heart rate; MI = myocardial infarction; Revasc =
revascularization