‘ Saibal Kar, M.D, FAHA, FACC, FSCAI Director of Interventional Cardiac Research Program Director of Interventional Cardiology Associate Professor of Medicine Curriculum Vitae PERSONAL HISTORY Business Address: 8631 West Third Street, 415 E Towers Los Angeles, CA 90048, USA Email: karsk@cshs.org, saibalkar60@gmail.com. Tel: (310) 423 3874 Fax: (310) 967 8323 Citizenship: United Kingdom Marital Status: Single EDUCATION 1977 –1979 1979 -1984 1984-1985 1987-1989 1990 1990 1991-1992 1993 1994-1996 1996 1996-1998 1998-2000 2000-2001 Premedical/Higher Secondary Education, St Xavier’s College, Calcutta, INDIA M.B, B.S, (Medical School Diploma), Nilratan Sircar Medical College, Calcutta University, Calcutta INDIA Internship. Nilratan Sircar Medical College. Calcutta, INDIA Residency in Internal Medicine. Post-Graduate Institute of Medical Education & Research, Chandigarh, INDIA Senior Resident in Internal Medicine, Post-graduate Institute of Medical Education & Research, Chandigarh, INDIA Senior Resident in Cardiology, Sanjay Gandhi Post-graduate Institute, Lucknow, INDIA Fellowship in Cardiology. Post-graduate Institute of Medical Education & Research, Chandigarh, INDIA Senior Resident (Post DM) in Cardiology, Post-graduate Institute of Medical Education & Research, Chandigarh, INDIA Fellowship in Interventional Cardiology. Epworth Hospital. Melbourne. Australia Internship(in USA). Dept of Medicine. West Los Angeles VA Medical Center, UCLA, Los Angeles. California Resident in Internal Medicine. UCLA. West Los Angeles VA Medical Center, Los Angeles, California Fellowship in Cardiology. UCLA. Cedars-Sinai Medical Center. Los Angeles, California. USA Fellowship in Interventional Cardiology. UCLA.Cedars-Sinai Medical Center. Los Angeles, California, USA Page 1 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI LICENSURE 1. 2. 3. West Bengal. INDIA. No 45013 since 1986 Medical Practitioners Board of Victoria. No MPS021710 March 24, 1994 to August 1, 1997 California, USA. No A063816 since October 1997 BOARD CERTIFICATION 1990 1990 1992 1995 1995 1996 1998 2000 2001 M.D.(Doctor of Medicine). Post-graduate Institute of Medical Education & Research, Chandigarh, INDIA Diplomate National Board of Medicine. New Delhi, INDIA D.M.(Doctor of Medicine in Cardiology). Post-graduate Institute of Medical Education & Research, Chandigarh, INDIA. USMLE(Step 1 and Step 2) ECFMG USMLE(Step 3) Diplomate in Internal Medicine. American Board of Internal Medicine Diplomate in Cardiovascular Diseases. American Board of Internal Medicine Diplomate in Interventional Cardiology. American Board of Internal Medicine PROFESSIONAL EXPERIENCE Present Position: Staff Cardiologist Director of Interventional Cardiac Research Division of Cardiology/ Department of Medicine Cedars Sinai Medical Center, Los Angeles, CA, USA Associate Professor of Medicine at David Geffen School of Medicine at UCLA, Los Angeles, CA. Previous Positions: 1. 2. 3. 4. 1998-2003: Intensivist. Good Samaritan Hospital, Los Angeles, California 1995-1996: Intensivist. St Vincent’s Hospital. Melbourne, Australia 1994-1996: Part time Emergency Medicine Physician. Epworth Hospital, Melbourne Australia 1993-1994: Assistant Professor, Division of Cardiology, Dept of Medicine Post-graduate Institute of Medical Education & Research, Chandigarh, INDIA Page 2 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI PROFESSIONAL ACTIVITIES Committee Service: 1. 2. 3. 4. 5. 6. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. Cardiac Cath Laboratory Advisory Committee, Cedars-Sinai Medical Center, Los Angeles Resident selection committee, Cedars Sinai Medical Center, Los Angeles. 2002, 2004 Scientific Advisory of Board. International Academy of Cardiology. 8th World Congress on Heart Failure Mechanisms, and Management: July 2002 Scientific Advisory of Board. 3 World Congress on Heart Disease: New Trends in research, diagnosis and treatment. 2003 Member of the Executive Committee for the CLOSURE I trial Member of Institution Review Board at Cedars Sinai Medical Center, Los Angeles, CA. since May 2006 Member of the Performance Improvement Committee: Cardiology, since 2002 Member of the Cath Lab Advisory Committee: Division of Cardiology, Cedars Sinai Medical Center, Los Angeles, CA Abstract Grader for the Society of Cardiovascular Angiography & Interventions (SCAI-American College of Cardiology Interventional Summit( SCAI-ACCI2 summit) since , 2008 Program Committee for the Annual Transcatheter Therapeutics Meeting Program Committee : American College of Cardiology i2 summit 2010, 2011, 2012, 2013,2014 Program Committee: American College of Cardiology annual conference 2011, 2012, 2013, 2014 Program Committee : Society of Cardiovascular Angiography & Interventions 2010, 2011 Program Committee: Transcatheter Therapeutics, 2012, 2013 Abstract Grader for Transcatheter Therapeutics Abstract Grader for American College of Cardiology 2010, 2011, 2012,2013 Abtract Grader for annual SCAI meeting 2010, 2011, 2012, 2013 PROFESSIONAL ASSOCIATIONS 1. 2. 3. 4. 5. 6. 7. Cardiological Society of India (Life member) Member of American College of Physicians: ACP # 01110339 Elected in 11/97 Fellow of American College of Cardiology, Sept 2002 Member of the American Medical Association since 1998 Fellow of the American Heart Association since 2001 Fellow of the Society of Cardiovascular Angiography and Interventions since 2004 Interventional Council of American College of Cardiology March 2012 to March 2015 MANUSCRIPT REVIEWER 1. 2. 3. 4. 5. 6. Journal American College of Cardiology American Journal of Cardiology International Journal of Cardiovascular Imaging Circulation: CardiovascularInterventions Echocardiography Journal American College of Cardiology: Interventions CONSULTING SERVICES 1. 2. .3. 4. 5. Medtronic Inc Gerson Lehrman Group Boston Scientific Abbott Vascular Gore Medical Page 3 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI HONORS AND AWARDS 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 1981 1984 Gold Medal in Anatomy. Nilratan Sircar Medical College, Calcutta, INDIA. First Certificate of Honors, Gynaecology and Obstretics, Nilratan Sircar Medical College, Calcutta. INDIA .1984 J.L. Poddar Gold Medal in Gynaecology and Obstetrics, Niltratan Sircar Medical College, Calcutta. INDIA 1984 Debendra Nath Dawn Medal in Gynaecology and Obstetrics, Nilratan Sircar Medical College, Calcutta. INDIA 1984 University Honors in General Surgery, Calcutta University, Calcutta, INDIA 1984 Highest Rank in University in the final MBBS examination, Nilratan Sircar Medical College, Calcutta, INDIA 1989 Silver Medal in Medicine. For distinguished performance in the final MD examination (board certification in medicine). Post-graduate Institute of Medical Education & Research, Chandigarh, INDIA 1997-98 Best Resident of the year: Internal Medicine, West Los Angeles VA Medical Center; UCLA 1997-98 Sherman Mellinkoff Best Resident Teacher Award of the Year: Internal Medicine; West Los Angeles VA Medical Center; UCLA 1999-00 Elliot Corday Outstanding Cardiology Fellow of the year 2003 Honored Member of of America’s Registry of Outstanding Professionals Ed 2003-2004 2007 Mentor Award 2006-2007: In recognition of Exceptional Mentorship in the Academic and Clinical Practice of Cardiovascular Medicine: Presented by the The Cardiology Fellows of Cedars Sinai Medical Center ’09 2007 Visiting Professor MC MEDICOR International Center for Cardiovascular Diseases, Slovenia May 2010. Second Prize for the Best of Best Abstract, Society of Cardiovascular Angiography and Interventions. March 25, 2012. Honored by the American Association of Cardiologist of Indian Origin RESEARCH GRANTS AND FELLOWSHIPS ACTIVE PRECLINICAL STUDIES Kar (PI) St Jude Medical 2/23/2011 to 3/31/2013 $700,000 1% HeartPOD Implantable Left Atrial Pressure Monitoring Device in a Canine Model-Training Protocol This is a animal model training protocol of training physicians to implant this device in humans for the clinical trial Role: Principal Investigator Kar(PI) Advanced Bifurcation Systems: 4/20/2009 to 11/30/2013 Preclinical evaluation of a novel bifurcation stent in porcine coronary arteries Role: Principal Investigator Page 4 of 65 1% Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Kar(PI) St Jude Medical 4/2/2007 to 3/31/2013 $900,000 1% Chronic evaluation of the HeartPod Implantable Left Atrial Pressure Monitoring Device in a Canine Model. In this initial study all animals have been implantable. The study is continuing to follow some of the survival animals Role: Principal Investigator Kar(PI) Circulite 4/08/2009 to 3/31/2013 $200,000 1% Acute evaluation of percutaneously delivered implantable assist device in a porcine model. This is the first of its kind transseptal Left atrial to aorta implantable device that is in development. The percutaneous delivery system is being evaluated for the fist time in our institution in preparation of a first in man study in 2013 Role: Principal Investigator Kar(PI) Valcare 9/26/2012 tp 09/30/2013 $100,000 1% Acute evaluation of transcatheter mitral valve repair using a Valcare Annuloplasty Ring. The aim of the study is develop and evaluate a method of transcatheter delivery and anchoring of this annuloplasty ring, prior to planning first in man study. This is the first animal study being performed with this device Role: Principal investigator ACTIVE CLINICAL TRIALS Kar (PI) Evalve Inc/Abbott Vascular 3/1/05 - 1/31/14 1% $95,000 EVEREST II clinical trial The goal of this study is demonstrate of the role of percutaneously delivered clip on the mitral valve for the treatment of mitral regurgitation. In this landmark Phase II study, our group is the lead enroller in the nation, This study completed enrollment in 2008. Patients will be followed till 2013. Role: Principal Investigator Kar(PI) Evalve Inc/Abbott Vascular 2/25/2009 to continuing $ 80,000 5% REALISM Prospective, multicenter continued access registry of the EVEREST II trial of the use of the MitraClip for the treatment of mitral regurgitation. The study will provide additional safety and effectiveness data in a real world condition to support premarket approval application(PMA). Lead enroller of this study. k Role: Principal Investigator Kar(PI) Abbott Vascularj ar(Principal Investigator) Abbott Vascular 2/27/2013- continuing Clinical Outcomes Assessment of the MitraClip Percutaneous Therapy for Extremely High Surgical Patients(The COAPT trial) IDE: G120024 Page 5 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Prospective randomized study comparing the MitraClip along with best medical therapy to best medical therapy alone for treatment severe functional mitral regurgitation patients who are not surgical candidates. All patients will be followed for 5 years 5/27/05 – 3/31/2013 Kar (PI) Atritech Inc/ Boston Scientific 1% $15,000 Protect AF study The goal of the study is to demonstrate the role of Percutaneous Atrial Appendage Occlusion as an alternative to long term anticoagulation for patients with Atrial fibrillation. (This clinical study is the first comparative study comparing medical treatment versus closure of Atrial appendage for the prevention of stroke. In view of the large number of patients with Atrial fibrillations if this study is positive it will create a large impact in the community. The study completed enrollment in 2008. Patients are still being followed for 5 years. Role: Principal Investigator Kar(PI) Atritech Inc/Boston Scientific 10/29/2008 to 3/31/2013 1% Continued Access Protocol (CAP registry) Prospective multicenter continued access registry of the use of the Watchman Device to provide additional safety and efficacy data to support premarket approval application(PMA). This registry completed enrollment in late 2009. This registry was stopped once the PREVAIL trial was conceived. We were the second highest enroller of this study. Role: Principal Investigator Kar(PI) Atritech Inc/Boston Scientific 01/28/2011 to Continuing $ 78,000 2% PREVAIL Trial This is confirmatory study to demonstrate the role of Percutaneous closure of the left atrial appendage occlusion using the Watchman device in the prevention of stroke in patients with non valvular atrial fibrillation who are at significant risk for stroke. Enrollment was completed in June 2012. All patients are being followed for 5 years. We were the second highest enroller of this study. Role: Principal Investigator Kar(Principal Investigator) (National Principal Investigator) Boston Scientific 4/15/2013 - 3/31/2014 Continuous Access to PREVAIL(CAP2) IDE: G020312 Prospective multicenter continued access registry of the use of the Watchman Device to provide additional safety and efficacy data to support premarket approval application(PMA). The inclusion and exclusion criteria are similar to that of the PREVAIL trial. In this study, Dr Kar serves as the national principal investigator Kar(PI) AGA Medical a subsidiary of St Jude Medical 9/21/2010 – continuing $60,000 1% Amplatzer Cardiac Plug study This is a pilot study to evaluate safety and efficacy percutaneous closure left atrial appendage using the amplatzer cardiac plug. The pilot study will be followed by a large scale multicenter randomized pivotal study. Pilot study has been completed and the randomized study has just started. Role: Principal Investigator Page 6 of 65 Curriculum Vitae Kar(PI) Gore Medical Saibal Kar, M.D, FAHA, FACC, FSCAI 9/30/2011 to continuing $20,000 1% REDUCE Trial Prospective, multicenter randomized study comparing closure of a patent foramen ovale using the GORE HELEX Septal Occuder plus antiplatelet therapy versus antiplatelet therapy alone in the secondary prevention of stroke in patients with a history of cryptogenic stroke and a patent foramen ovale. Role: Principal Investigator. Makkar(PI) Edwards Lifesciences 3/25/2011 to continuing 1% The PARTNER II trial Prospective randomized study comparing Edwards Sapien XT transcatheter aortic valve to conventional surgical valve replacement for the treatment of severe aortic valve stenosis in moderate surgical risk patients. Role: Co-investigator Zahn(PI) Edwards Lifesciences 04/09/2009 to continuing 1% The COMPASSION Study Prospective multicenter study evaluating the role of the Edwards Sapien transcatheter valve in the pulmonic valve in patients with a history of failed surgical conduits in the right ventricular outflow tract. Role: Co-investigator C Noel Bairey Merz NIH: National Institutes Of Health 5/14/2008 to continuing 5% Women’s Ischemia Syndrome Evaluation(WISE) Coronary Vascular Dysfunction In this study it planned to determine whether coronary vascular dysfunction predicts abnormalities in cardiac MRI imagng. In addition to determine whether these abnormalities detected by MRI are actually predictive of adverse outcomes in women with angina with angiographically normal coronaries with abnormal function. Role: Co-investigator ,Czer, L (PI) St Jude Medical 3/19/2012 to 2/28/2013 1% Left Atrial Pressure Monitoring to Optimize Heart Failure Therapy Study (LAPTOP-HF) Prospective, multicenter, randomized controlled clinical trial comparing safety and effectiveness of treatment of heart failure guided by left atrial pressure monitoring system versus standard of care. My role is to implant the left atrial pressure system in patients who are randomized to receive the device Role: Co-investigator Makkar(PI) Edwards Lifesciences 10/18/2007 to 8/31/2013 01% THE PARTNER Trial Prospective, multicenter, randomized trial comparing Edwards SAPIEN Transcatheter Heart Valve versus surgical treatment or medical treatment for aortic stenosis in patients who very high risk or extreme risk for conventional cardiac surgery. The trial has completed enrollment and at present patients enrolled in the study are being followed for a total of 5 years. Page 7 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Role: Co-investigator Makkar(PI) Medtronic 8/15/2012 to 7/31/2013 1% Symplicity HNT 3, Renal Denervation in Patients with Uncontrolled Hypertension 10,000 Prospective, multicenter, randomized, controlled study comparing renal denervation versus conventional medical treatment for resistant hypertension. This is novel study evaluating a new treatment for hypertension. Role: Co-investigator Shah (PI) St Judes Medical 10/31/2005 to 6/30/2013 $60,000 5% HOMEOSTASIS TRIAL The Phase I study in US is to demonstrate the safety and efficacy of chronic left atrial pressure monitoring using the Heart POD device in patients with chronic heart failure patients. This novel device was invented in Cedars Sinai Hospital. Dr Eigler, Dr Whiting and Dr Kar were involved in the preclinical development of this product. The enrollment of this phase of this study has been completed, patients are being followed. Role: Co-investigator in this study. Plays an important role in proctoring physicians all over the world involved in this study in proper deployment of this device. Role: Co-Investigator 4/23/2013 – continuing Makkar(Principal Investigator) Abbott Vascular EXCEL: Evaluation of XIENCE PRIME™ or XIENCE V® versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization This is a randomized study comparing surgical revascularization versus stenting of the left main coronary artery. This will be a long term follow up study Role: Co-investigator LECTURES AND PRESENTATIONS Cardiology Grand Rounds: West Los Angeles VA Medical Center. July 2001 Mitral valvuloplasty “Current status of Mitral valvuloplasty”, Cardiology Grand Rounds: UCLA Harbor, Torrance, CA. Feb 2002 “Percutaneous Closure of Patent Foramen Ovale in pts with Neurological Events”, 8th World Congress of Heart Failure, July 2002, Washington “Treatment of Patent Foramen Ovale with Stroke: Coumadin vs. Closure “, Stroke Update, Dept of Neurology, Cedars Sinai Medical Center, Los Angeles, June 2002 Page 8 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI “Heart Sounds” Clinical Medical Lecture Series, Dept of Medicine, Cedars Sinai Medical Center, Los Angeles, June 2002 “Everolimus eluting stents prevents in-stent restenosis without toxicity in a porcine model” Research and Progress, Division of Cardiology, Cedars Sinai Medical Center, Los Angeles, July 2002. “Catheter Based Closure of Patent Foramen Ovale with history of Neurological Events”. International Academy of Cardiology: 8th World Congress on Heart Failure: Mechanisms and Management. July 15, 2002 “Patent foramen Ovale and Neurological Events Neurological Grand Rounds”, Neurology Grand Rounds, Cedars Sinai Medical Center, Los Angeles, August 23, 2002. “Percutaneous Closure of Patent Foramen Ovale and Atrial Septal Defects”, Cardiology Grand Rounds, Cedars Sinai Medical Center, Los Angeles, August 27, 2002 “Histological Analysis of Elution of Everolimus from a Biodegradable Polymer Coated Stent” Industry Breakfast Symposium, Transcatheter Cardiovascular Therapeutics, Washington, September 2002. “Efficacy of Elution of Everolimus from a Biodegradable Polymer Coated Biosensors Stent in prevention of In stent Restenosis in a Porcine Model: one and three month data, The Drug-Eluting Stent Summit, Transcatheter Cardiovascular Therapeutics, September 2002 Drug Coated Stents: “Promises and Reality”. CARDICOM 2003, Sanjay Gandhi Postgraduate Institute, Lucknow, INDIA “Percutaneous Closure of Patent Foramen Ovale and Atrial Septal Defects”, Lecture to the Advanced Nurse Practice Committee. Cedars Sinai Medical Center, Los Angeles, CA. March 13, 2003. “Primary Percutaneous Coronary Intervention- beyond Epicardial Patency”. Invited Lecture for symposium of Acute Coronary Syndromes in Slovenia. Bled, Slovenia. April 12, 2003 “Drug Eluting Stents: Bench to Bedside. Invited Lecture for Division of Cardiology, University Medical Center, Ljubljana, Slovenia. April 14, 2003 “Important Highlight of Inteventional Cardiology: ACC 2003”. Cardiology Grand Rounds, Cedars-Sinai Medical Center, Los Angeles, CA. April 29, 2003 “Use of Intracardiac Echocardiography for Closure of ASDs and PFOs” . 3rd World Congress of Heart Diseases- New Trends in Research, Diagnosis, and Treatment. Washington DC, July 13, 2003. “Percutaneous Transluminal Septal Myocardial Ablation for Treatment of Symptomatic Hypertrophic Cardiomyopathy.”.Japanese Association of Cardiovascular Catheterization Therapeutics (JACCT) , Sendia, JAPAN. July 31 to Aug 2. “Is Everolimus the next main contender Clinical DES Contender? Results from FUTURE I and II” . Drug Eluting Stent Summit. Transcatheter Therapeutics(TCT) September 19, 2003 “Use of the Porcine Model for Cardiac Research”. Tri Branch Fall Symposium hosted by Southern California Branch of AALAS. City of Hope September 10, 2003 “Closing Heart Defects” Does it Really help in Preventing strokes”. Cardiology Grand Rounds. Cedars Sinai Medical Center, Los Angeles. October 7, 2003. “Role of closing heart defects in the prevention of stroke”.. Page 9 of 65 Dallas, October 26, 2003. Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI “Intracardiac Echocardiography: A new tool to guide procedure in the Catheterization Laboratory. Grand Rounds. Echo Society Meeting. Salt Lake City, Utah. January 22, 2003. “Percutaneous Closure of Cardiac Defects: A true reality”. Cardiology Grand Rounds. Harbor- UCLA. Torrance. California. February 2, 2004 “Pharmacoinvasive approach for Acute coronary syndrome: Transition to Percutaneous Coronary Intervention. Noon Conference. UCLA Harbor, Torrance, California September 13, 2004. Transcatheter Therapeutics: Immunomodulation and Vaccines for Atherosclerosis. Washington DC, September 27, 2004 Transcatheter Therapeutics: HDL based Immune modulation for Atherosclerosis. Washington DC, Sept 28, 2004. Transcatheter Therapeutics, Washington DC. Featured Lecture: The Molecular Basis of Vulnerable Plaque. September 30, 2004 Cardiology Grand rounds. Indications of closure of atrial communation. 2004. Kaiser Hospital, Honolulu, Hawaii. Pharmacortherapy of acute coronary syndrome. Cardiology Grand Rounds. St Joseph Hospital, Orange County, January 5, 2005. Management of acute coronary syndrome. Grand rounds. “Umbrellas, Pills or Sutures in the treatment of Cardioembolic stroke. Update. Neurology update. San Diego 2/19/05. “CoStar Paclitaxel eluting Stent” . Bench to Bedside. Invited lecture. Hyderabad. Feb 23, 2005 “Chairperson: Use of betablockers in acute myocardial infarction, 2nd World Congress of Interventional Cardiology. Bombay, India. February 24, 2005. “Chairperson: Costar 1 clinical results. 2nd World Congress of Interventional Cardiology. Bombay, INDIA. February 25, 2005. Medicine Grand Rounds: Etiology and management of Cardioembolic Stroke. Cedars Sinai Medical Center. April 29, 2005. Cardiology Grand Rounds: Chronic left atrial pressure monitoring for heart failure patients: concept to reality. Epworth Hospital, Melbourne, July 13, 2005 International Pediatric Conference: Invited Speaker: Use of the Heart POD device in monitoring left atrial pressure: First human experience. Pediatric Interventional Cardiac Symposium, Buenos Aires, Sept 18, 2005 Transcatheter Therapeutics: Invited Speaker: Normal and Abnormal responses of Drug Eluting Stents: Insights from animal models and cadaveric studies, Morphological effects of drug eluting stents: insights from animal and cadaver studies. October 19, 2005, Washington DC Cardiology Grand Rounds: Update on the use of antithrombotics in Acute Coronary Syndrome Patients. Division of Cardiology, Loma Linda Medical Center, CA, USA. Nov 2005. Page 10 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Cardiology Grand Rounds: Percutaneous Mitral Valve Repair: Division of Cardiology, Cedars Sinai Medical Center, Los Angeles, CA, January 25, 2006 SingaporeLIVE2006: Judge Best of Young Interventionalist Competition. Singapore. 27 February 2006 SingaporeLIVE 2006: Invited Speaker: Preclinical Safety of Biolimus A9 Delivered from a Bioresorbable Polymer Coated Stent-Preclinical Data. 27 February 2006 SingaporeLIVE 2006: Moderator: Clinical Cases. Suntec, Singapore. 28 February 2006 SingaporeLIVE 2006: Panelist: Complex Coronary issues/complications. Suntec, Singapore. 28 February 2006 Cardiology Grand Rounds: Edge to Edge repair of Mitral Valve: A reality: Division of Cardiology, White Memorial Hospital, March 23, 2006 ELA D&T Spring Meeting: Percutaneous Mitral Valve Repair vs Surgery for Mitral Regurgitation. El Paso De Robles, California, April 8, 2006 Clinical Neurology and Neurosurgery Update: Advances in Cardioembolic Stroke: Role of Interventional Cardiology versus Medical Treatment, Red Rock Casino Resort, Las Vegas, April 29, 2006 SingaporeLIVE 2006: Guest Lecture: Percutaneous Mitral Valve Repair with the MitraClip. Suntec, Singapore. 28 February 2006 Oriental Endovascular Therapy (OET): Bioabsorbable Polymer Drug Eluting Stent (EXCEL): Results of Animal Study(Invited Lecture): June 10, 2006 Oriental Endovascular Therapy (OET): Percutaneous Mitral Valve Repair Using the Edge to Edge Technique: A Concept to Reality (Invited Lecture): June 10, 2006 Cardiology Grand Rounds: Division of Cardiology, Scripps Green Hospital, San Diego: Percutaneous Mitral Valve Repair using the Edge to Edge Technique. September 6, 2006 Stroke and Rehabilitation Conference, Los Angeles. La Meridian Hotel, Los Angeles. Umbrella, Pills Sutures for the treatment of Cardioembolic Stroke. September 9, 2006 Medicine Grand Rounds: Dept of Medicine. Cedars Sinai Medical Center, Los Angeles. Percutaneous Mitral Valve Repair: Concept to Reality. September 15, 2006 Scientific Symposium: 25th Anniversary of Epworth Hospital Cardiac Center. Current Status on Percutaneous Mitral Valve Repair. Melbourne, Australia, October 6, 2006 Research in Progress Rounds: Overview of Interventions for Structural heart Disease. Methodist Hospital, Houston, Texas, October 16, 2006 Transcatheter Therapeutics: Invited Speaker: Case Study: Structural Heart Disease Symposium,TCT, Washington DC, October 22, 2006 Transcatheter Therapeutics: Moderator during a Live Case Session: Case: Structural Heart Disease TCT, Washington DC, October 23, 2006 Kardioloski Dnevi: 14th Scientific Meeting of the Slovenian Society of Cardiology with Interventional Participation. Invited Speaker: Umbrellas, Pills, and Sutures for the Treatment of Cardioembolic Stroke. Portoroz, Slovenia, October 25th, 2006 Page 11 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Kardioloski Dnevi: 14th Scientific Meeting of the Slovenian Society of Cardiology with Interventional Participation. Invited Speaker: Morphological effects of drug eluting stents-lessons learnt from preclinical and human pathology studies. Portoroz, Slovenia, October 28th, 2006 Kardioloski Dnevi: 14th Scientific Meeting of the Slovenian Society of Cardiology with Interventional Participation. Invited Speaker: Percutaneous Mitral Valve Repair using the Edge to Edge Technique. Portoroz, Slovenia, October 28th, 2006 Update on Electrophysiology; Symposium: Percutaneous Closure of Left Atrial Appendage of Atrial fibrillation. W Hotel, San Diego, CA. October 4, 2006 Medicine Grand Rounds: Endovascular Repair of Cardiac Defects: Update. Cedars Sinai Medical Center, Los Angeles, CA, US November 10th, 2006 Medicine Noon Conference: Management of Acute Coronary Syndromes: Cedars Sinai Medical Center, Los Angeles, CA October 2006 Vascular Interventions 2006. Preclinical Development of the CoStar Stent: results and the glimpse into the future. Istanbul, Turkey, November 23rd 2006 Cardiology Noon Conference. Percutaneous Mitral Valve Repair. Dept of Cardiology, St Lukes Hospital, Milwakee. December 6, 2006 Invited Speaker: International Conference: Percutaneous Mitral Valve Repair using the MitraClip (Evalve Inc). 3-C Con 2007, Ahmedabad, India, January 26, 2007 Invited Speaker: International Conference: Closure of Patent Foramen Ovale for Stroke, Where are we in 2007. 3-C Con 2007, Ahmedabad, India, January 26, 2007 Invited Speaker: Topic: How to do a Coronary Reactivity Study Conference: Women and Ischemic Heart Disease (offered in cooperation with the California Chapter of the American College of Cardiology). Cedars Sinai Medical Center, Los Angeles, CA, US. April 28, 2007 Invited Speaker: Topic: Mitral Clip Procedure. Conference: Congenital and Structural Heart & Interventions (CSI) Frankfurt 2007. June 8, 2007 Invited Speaker: Topic: Current Status of the Edge to Edge Mitral Valve Repair Conference: Congenital and Structural Heart & Interventions (CSI) Frankfurt 2007, June 8, 2007 Invited Faculty: Panelist: Transcatheter Mitral Valve Repair Conference: Congenital and Structural Heart & Interventions (CSI) Frankfurt 2007, June 8, 2007 Invited Speaker: Topic: Chronic Left Atrial Pressure Monitoring for Patients with Heart failure: The Homeostasis Study. Conference: Congenital and Structural Heart & Interventions (CSI) Frankfurt 2007. June 9, 2007 Invited Speaker: Topic: Percutaneous Mitral Valve Repair (25 minutes) Annual Conference of the Cardiac Society of Australia & New Zealand (CSANZ 2007) August 11, 2007 Invited Speaker: Topic: Left Atrial Appendage devices: the death knell for warfarin? (20 min) – “James Hay Theatre”. Annual Conference of the Cardiac Society of Australia & New Zealand (CSANZ 2007) August 12, 2007 Invited Speaker: Topic: Transcatheter Repair of Mitral Valve. 19th Annual Meeting of the Mediterranean Association of Cardiology and Cardiac Surgery, in Opatija, Croatia, Hotel Ambassador, 27-30 September Page 12 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 2007 Invited Speaker: Topic: Advances in prevention of Cardioembolic Stroke: Role of a newer Interventional Techniques. Noon Conference, Dept of Cardiology, Tarzana Hospital. June 19th 2007 Invited Speaker:Topic. New Therapeutic Interventions for LV dysfunction. Mid year Update on Cardiac Rhythm Management. Viceroy Santa Monica. July 7, 2007 Cardiology Grand Rounds: Update on Percutaneous Mitral Valve Repair using the MitraClip Dept of Cardiology, Cedars Sinai Medical Center. July 24th, 2007 Noon Cardiology Grand RoundsConference: Valvuloplasty: An Update. Division of Cardiology, Fountain Valley Regional Hospital, Foutain Valley, CA. August 6, 2007 Core Lecture for Fellows: History of Cardiac Catheterization. Division of Cardiology, Cedars Sinai Medical Center, Los Angeles, CA. July 23, 2007 Medicine Grand Rounds. Umbrellas and Plugs for the prevention of Cardioembolic Stroke: Is it a Death Knell for Coumadin? Dept of Medicine, Cedars Sinai Medical Center, Los Angeles, CA. September 7, 2007 Invited Speaker and Faculty: Topic: Cross fire Debate: Percutaeous Mitral Valve Repair. Controversies and Advances in the Treatment of Cardiovascular Disease. The Seventh in the Series. Oct 4 -5, 2007 Cath Grand Rounds: UCLA. Percutaneous Mitral Valve Repair: concept to reality. W Hotel, Westwood, Los Angeles, CA. Nov 15, 2007 Evalve Investigators Meeting for the EVEREST II clinical trial. MitraClip procedure. Sheraton Hotel, San Francisco, January 10th, 2008 Evalve Investigators Meeting for the EVEREST II clinical trial. Recruitment for patients for the EVEREST II clinical trial. Sheraton Hotel, San Franciso, Jan 10th, 2008. Invited Speaker. Advances in Interventional Cardiology: Is Cardiac Surgery Obsolete. Annual meeting in the West LA VA Hospital, Jan 25, 2008 Invited Lecture: The role of the HeartPOD device in heart failure patients. 4th Asian Pacific Heart Congress of Heart Failure. Melbourne, Australia. February 1, 2008 Invited Speaker. Percutaneous Mitral Valve Repair. Conference: Heart Failure An Update of Therapy 2008. Millennium Biltmore Hotel, Los Angeles, Feb 2, 2008 Invited Speaker/Faculty: Percutaneous Mitral Valve Repair: Using the MitraClip. The second Live Demonstration Course in Basic & Advanced Interventional Cardiology, Dubai, UAE. March 26th, 2008 Invited Faculty: CoModerator: Live Case Transmission The second Live Demonstration Course in Basic & Advanced Interventional Cardiology, Dubai, UAE. March 25,26, 2008. Invited Speaker/Faculty: Percutaneous Mitral Valve Repair. Invited Lecture. American College of Cardiology/Interventional 2 Summit. Mitral Edge to Edge Repair. Chicago, March 31, 2008 Invited Faculty: Panelist: Understanding Mitral Regurgitation: Insights into interventional therapy for structural and functional MR. March 31, 2008 Invited Speaker: Catheter Based treatment of mitral valve disease. Los Robles Conference at the Sherwood Club, Westlake Village, CA April 12, 2008 Page 13 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: Percutaneous repair/replacement of cardiac Valves. Annula Meeting of the National Interventional Council of India, Kolkata, India. April 19, 2008 Invited Speaker. Medtronic Endeavor Program. Bistro, Bakersfield, CA. April 24, 2008 Invited Lecture: Percutaneous Valve Repair/replacement: Updatedd, Cardiovascular Conference St Judes Medical Center, Fullerton, CA. May 8, 2008 Invited Lecture: Case example of Percutaneous Mitral Valve Repair: Catheter based therapy for Structural Heart Disease symposium: American Association of Thoracic Surgeons annual Meeting. May 10, 2008, San Diego Invited Lecture: Catheter Based treatment of ASD, PFO, VSD.:at Symposium on Catheter based approaches for Structural Heart disease. American Association of Thoracic Surgeons annual Meeting. May 10, 2008. San Diego Invited Lecture.:Representative Clinical examples of PMR with the MitraClip Device/ symposium on mitral valve repair. EuroPCR., Barcelona, Spain, May 14, 2008 Invited Speaker/Facutly: 2nd Annual Women and Ischemic Heart Disease Symposium: Unique Challenges and Case Review. Gender-specific Invasive Coronary Reactivity Testing. Cedars Sinai Medical Center, Los Angeles, CA. May 28, 2008 Invited Speaker; Drug-Eluting Stent Update. 1st Annual State of the Art Nevada Cardiovascular Symposium. Mesquite, Nevada, US. May 31, 2008 Invited Speaker; Drug-Eluting Stent Update. 1st Annual State of the Art Nevada Cardiovascular Symposium. Mesquite, Nevada, US. May 31, 2008 Invited Speaker/Faculty: Taped Case demonstration using the MitraClip Valve repair system. Transcatheter Valve therapies. Seattle, Washington. June 6, 2008 Invited Faculty: Evalve Mitral Valve system: Pt screening, selection, and procedural details. Transcatheter Valve Therapies, Seattle, Washington, June 6, 2008 Invited Speaker/Faculty: Transcatheter Mitral Valve Repair-Edge to Edge Repair Works!. Conference: Congenital and Structural Heart & Interventions(CSI) Frankfurt 2007.Frankfurt, June 27, 2008 Invited Speaker/Faculty: Mitral Valve Edge to Edge Repair-Problems and Complications. Conference: Congenital and Structural Heart & Interventions(CSI) Frankfurt 2008.Frankfurt, June 27, 2008 Invited Speaker/Faculty: Monitoring of Left Atrial Pressure for management of Heart failure. Congenital and Structural Heart & Interventions(CSI) Frankfurt 2008, June 28, 2008 Invited Speaker/Faculty: Update on the Endeavor Stent Platform. Cardiology Consultants of Bozeman, Bozeman, Montana July 10, 2008 Invited Speaker: The Endeavor Stent Platform. Great Fall Cardiac Group, Benefis East Hospital, Great Falls, Montana, July 11, 2008 Invited Speaker: Clinical Studies on the Endeavor Stent Platform. Montana Heart Center, Montana. July 11, 2008 Invited Speaker/Faculty: Percutaneous Monitoring of Left Atrial Pressure Monitoring Pediatric and Adult Intervention Cardiac Symposium(PICS-AICS 2008). Las Vegas, July 22, 2008 Invited Speaker/Faculty: Current and Future Approach to the Treatment of Mitral Valve Regurgitation: Page 14 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Percutaneous Edge to Edge Repair. Controversies & Advances in the Treatment of Cardiovascular Disease-8th Series (Beverly Hills Hotel), September 4, 2008 Invited Speaker/Faculty: Chairperson : Debate: PFO closure for stroke : Clinical trials are required, versus standard of care. Controversies & Advances in the Treatment of Cardiovascular Disease-8th Series (Beverly Hills Hotel), September 5, 2008 Invited Lecture: Percutaneous mitral valve therapy: the edge to edge repair. Scripps Clinic 19th Annual Conference, Coronary Interventions, Hilton La Jolla Torrey Pines in San Diego, September 18, 2008 Invited Speaker: Percutaneous Mitral Valve Repair: Cardiovascular Disease Between Intervention and Surgery German Heart Center, Munich, Nov 6, 2008 Invited Speaker: Percutaneous Mitral Valve Repair. Interactive Forum for Interventions in Structural and Congenital Heart Disease. Kochi, India Nov 8, 2008 Invited Speaker/Faculty: Judkins Imaging Symposium: Speaker and Chairman. SCAI 32nd Annuals Scientific Sessions May 6-9, 2009, Caesars Palace, Las Vegas Cardiology Grand Rounds. Advances in Interventions for Structural Heart disease: Percutaneous Mitral Valve Repair and Left Atrial Appendage Occlusion for atrial fibrillation. Dept of Cardiology, Alfred Hospital, November 11, 2008 Invited Speaker. Percutaneous repair of structural heart defects. Medicor Symposium, Portoroz, Slovenia EU. December 6, 2008 Invited Speaker: Interventional Closure of PFOs: Indications and Techniques Symposium on Neurovascular Disease 2009 (Sponsored by Dept of Neurosciences, Cedars Sinai Medical Center, CA. Casa Del Mar Hotel, Los Angeles, CA, January 10, 2009 Invited Speaker. Update on EVEREST edge to edge repair trials. I2 Summit at American College of Cardiology Meeting, Orlando, Florida, March 29, 2009 Invited Speaker. Shock and Aortic Stenosis in the Cath Lab. I2 Summit at the Annual American College of Cardiology Meeting, Orlando, Florida, March 30, 2009 Invited Speaker. Percutaneous Treatment of Structural Heart Defects. Cardiology Grand Rounds. Sendai Kosei Hospital, Sendai, Japan March 18. 2009 Invited Speaker: Update of Percutaneous treatment of structural heart defects. Interventional Cardiology Fellows Forum. 8th meeting of acute coronary syndromes. Blyth, Slovenia. March 20, 2009 Invited Speaker: Percutaneous Aortic Valve Replacement and Mitral Valve Repair. Cardiology Grand Rounds. Holly Cross Hospital Invited Speaker: PFO and Strokes/Update: 3rd Annual Cardiovascular Symposium organized by Los Robles Hospital. Sherwood Country Club, Thousand Oaks, CA. April 18, 2009 Invited Faculty: Moderator: Judkins Imaging Symposium: Echo in the Cath Lab. Annual Society of Cardiovascular And Angiography Interventions. Caesars Palace, Las Vegas, May 6, 2009 Invited Speaker: Advanced transseptal challenges, special situations and procedure specific approaches. Annual Society of Cardiovascular And Angiography Interventions. Symposium on working in the LA, Caesars Palace, Las Vegas, May 9, 2009 Invited Speaker: Topic: Microvascular Angina Management: Case Review) 3rd Annual Women and Ischemic Heart Disease Symposium, at Cedars-Sinai Medical Center in Los Angeles, May 13, 2009 Page 15 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: Imaging Strategy for Edge to Edge Repair- in the plenary session of Mitral valve incompetency: imaging and hemodynamics. EuroPCR, Barcelona. May 20th 2009 Invited Speaker:. Experience with the MitraClip therapy in the EVEREST II high risk. In the Symposium on Mitra Clip Experience in Europe and North America. EuroPCR, Barcelona. May 20th 2009 Invited Speaker: MitraClip Technology: Symposium on ACCESS- Europe: May 19, 2009, Barcelona, Spain Invited Speaker: Mitral Valve Regurgitation: Percutaneous Therapies- State of the Art Overview. Pediatric and Adult Interventional Cardiac Symposium- in conjuction with the World Congress of Pediatric Cardiology. Cains, Australia June 22, 2009 Invited Speaker: Structural Heart Disease Interventions: Heart Failure Monitoring Devices: Where are we? Where are we heading ? Pediatric and Adult Interventional Cardiac Symposium- in conjuction with the World Congress of Pediatric Cardiology. Cains, Australia June 22, 2009 Invited Speaker: Step-by-Step MitraClip for Mitral Valve Prolapse (Edited Taped Case) Transcatheter Valve Therapies: June 25, Grand Hyatt, Seattle, WA Invited Speaker: My Most memorable Transcatheter Mitral Valve Therapy Case(Success or Complication): Transcatheter Valve Therapies, June 25th 2009, Grand Hyatt, Seattle, WA Invited Faculty: Directors of the Session of the Transcatheter Evalve MitraClip Device. Transcatheter Valve Therapies, June 26, 2009, Grand Hyatt, Seattle, WA Invited Faculty: Advanced Imaging for Transcatheter Valve Therapies Transcatheter Valve Therapies, June 26, 2009, Grand Hyatt, Seattle, WA Invited Faculty: Leaflet Apposition- Concept and Techniques. Congenital & Structural Interventions, Congress Center Messe Frankfurt Germany, July 11, 2009 Invited Speaker. Implantable Devices to Measure Cardiac Function in Chronic Heart Failure – HeartPOD. Congenital & Structural Interventions, Congress Center Messe Frankfurt Germany, July 11, 2009 Invited Speaker: Hoag Endovascular Summit 2009: Nightmares and Dreamscapes Case presenter(2 cases) : He Blew I blew almost blew it too. Look Around. The Island Hotel, Newport Beach, CA August 9, 2009-08-07 Invited Speaker: Endovascular Summit 2009: Nightmares and Dreamscapes Moderator. The Island Hotel, Newport Beach, CA August 9, 2009-08-07 Invited Speaker: Percutaneous Mitral Valve Repair and Replacement. At the 20th Annual Conference of Scripps Clinic on Coronary Interventions. Hilton La Jolla Torrey Pines, San Diego, October 30, 2009 Invited Speaker: Role: Discussant: Transcatheter Therapeutics Coronary Arteriovensous Malformation: Case Presentations. Sept 21, 2009, San Francisco, CA Invited Speaker: Transcatheter Therapeutics . Hemodynamic Assessment of Mitral Regurgitation (and Percutaneous Mitral Valve Repair), and 3 Ways to be Fooled (with Case Presentations). Sept 22, 2009, San Francisco, CA Invited Speaker: Transcatheter TherapeuticsEchocardiographic Diagnosis of Hypertrophic ardiomyopathy and Use During the Alcohol Septal Ablation. Sept 22, 2009 Invited Speaker: Transcatheter Therapeutics .A Step-by-Step Approach Using the Percutaneous Edge to Edge Evalve MitraClip System.. Sept 22, 2009, San Francisco, CA Page 16 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: Transcatheter Therapeutics . Imaging Guidance of PFO and ASD Closure Sept 23, 2009, San Francisco, CA Invited Speaker: Transcatheter Therapeutics . The Coronary Sinus as a Mitral Valve Target: Insights From Imaging Sept 25, 2009, San Francisco, CA Invited Speaker: Moderator: Novel Transcatheter Valve Therapies Under Development.Session II. Miral Valve Therapies Prior to and In Human Investigation Direct Annuloplasty Systems. Sept 25, 2009 Invited Speaker: Transcatheter Therapeutics . Image guidance of Evalve Clipping. Sept 24, 2009, San Francisco, CA. Invited Speaker: Transcatheter Mitral Valve Repair and Replacement. Scripps Clinic’s 20th Annual Conference on Coronary Interventions, La Jolla, CA, October 30, 2009 Invited Speaker: Cardiology Grand Rounds: Monash Medical Center. Left Atrial Appendage Occlusion for the prevention of cardioembolic stroke. November 25, 2009 Invited Speaker: Tips in the management of patients, Lessons learnt from the US experience. Key Opinion Leader Meeting in Europe for MitraClip Therapy. Abbott Crossroads Center, Brussels, Dec 8, 2009 Core Curriculum Lecture for the EP Fellows in Cedars Sinai Medical Center. Intracardiac Echocardiography for Septal and Left atrial interventions. Dec 10, 2009 Invited Speaker: 1st Annual Arrhythmia Symposium at Cedars Sinai Heart Institute: Atrial Appendage Occluder for Stroke Prophylaxis: Just lock the appendage and throw away the key. Harvey Morse Auditorium, Cedars Sinai Medical Center, Los Angeles, Dec 11, 2009 Invited Speaker: Topic: Potential future alternative therapeutic options for patients with functional mitral regurgitation. Breakfast Symposium on the Pathophysiology and treatment consideration for patients with functional mitral Regurgitation. Annual Society of Thoracic Surgeons Meeting. Fort Lauderdale, Florida January 25, 2010 Invited Speaker: Erodable Polymer and Polymer Free Stents: BioMatrix and Biofreedom etc, India Live 2010, New Delhi, February Invited Faculty: Moderator of Live Session, India Live 2010 Invited Speaker ; Visionary Interventional Procedures to treat Common Disorders: Heart Failure, Systemic Hypertension and Beyond. i2 Summit of the Annual Meeting of the American College Cardiology, Atlanta, March 14, 2010 Invited Speaker; Clinical Experience with the Percutaneous Edge to Edge Repair.. i2 Summit of the Annual Meeting of the American College Cardiology, Atlanta, March 14, 2010 Invited Speaker; Evaluation and Management of Unstable Angina/Non ST elevation myocardial infarction. .Annual Meeting of the American College Cardiology, Atlanta, March 15, 2010 Invited Faculty; Co-Chairperson: Core-Curriculum series: Coronary Artery Disease. Annual Meeting of the American College Cardiology, Atlanta, March 15, 2010 Invited Speaker; Technique of left atrial appendage occlusion. . i2 Summit of the Annual Meeting of the American College Cardiology, Atlanta, March 15, 2010 Invited Speaker/Faculty: Update on Percutaneous Pulmonary Valve Replacement. Concepts in Contemporary Cardiovascular Medicine(CCC 2010) Houston April 8, 2010 Invited Faculty: Panelist for the live case demonstrations from Memorial Hermann Heart & Vascular Page 17 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Institute. Houston April 8, 2010 Invited Faculty: Congenital Heart Disease and Pulmonary Hypertension. At Pulmonary hypertension in all its Diversity: 2010 State of the Art for the Clinician. At Cedars Sinai Medical Center, April 10, 2010 Invited Faculty: Percutaneous Valve Surgery. 7th Annual Cardiology Symposium – Menifee Valley Medical Center, Sun City, CA. April 10, 2010 Invited Speaker: Devices for Stroke Prevention: Left Atrial Appendage Occluders and PFO closure Devices 11th Annual Monterey Bay Regional Heart Symposium. The Clement Monterey Hotel, Monterey, CA, April 30, 2010. Invited Speaker: Percutaneous Mitral Valve Repair 11th Annual Monterey Bay Regional Heart Symposium. The Clement Monterey Hotel, Monterey, CA, April 30, 2010. Invited Speaker: Percutaneous Aortic Valve Replacement. 11th Annual Monterey Bay Regional Heart Symposium. The Clement Monterey Hotel, Monterey, CA, April 30, 2010. Invited Speaker:2010 Adult Cardiac Skills Course Annual American Thoracic Society Meeting, Metro Toronto Convention Center, Toronto, Canada. May 1, 2010. Invited Speaker:2010. EVEREST II Clinical trial.Annual American Thoracic Society Meeting, Metro Toronto Convention Center, Toronto, Canada. May 1, 2010. Invited Speaker/Faculty: Panelist: MitraClip Symposium. Sapphire A Room, in Hilton San Diego Bayfront. 33rd Annual Meeting of SCAI, San Diego, CA, May 6, 2010. Invited Speaker. How to Maximise Enrollment in Clinical Trials: A Cardiologist’s perspective. 33rd Annual Meeting of SCAI, San Diego, CA May 7, 2010. Invited Speaker. Imaging in Structural Heart Disease Symposium. 33rd Annual Meeting of SCAI, San Diego, CA May 7, 2010. Invited Faculty: Case Reviews:Who should undergo invasive coronary reactivity testing ? Women & Ischemic Heart Disease Symposium. Cedars Sinai Medical Center, CA. May 12, 2010. Invited Speaker: Percutaneous Mitral Valve Repair. Los Robles Cardiovascular Symposium. Sherwood Country Club, Thousand Oaks, CA. May 15, 2010. Invited Speaker. Practical Use of Different Imaging Modalities( Pre, intra, and post procedure during Mitral Valve interventions. 33rd Annual Meeting of SCAI, San Diego, CA May 7, 2010. Invited Faculty/Speaker: Mitral valve repair: detailed review of the EVEREST II randomised study. EuroPCR 2010. Paris, May 26, 2010 Invited Faculty/Speaker: MitraClip Procedure Overview. EuroPCR 2010. Paris, May 28, 2010. Invited Faculty/Speaker: Provocative discussion: transcatheter mitral valve repair. EuroPCR 2010, Paris, May 28, 2010. Invited Speaker: Session: MitraClip Device: Device Description and the Step-by-Step Technique. Transcatheter Valve Therapies 2010. June 7, 2010. Invited Faculty Session II Live Case Demonstrations: Transcatheter Valve Therapies 2010. June 7, 2010. Invited Speaker: Panel Discussant:The Present and Future of Edge-to-Edge Repair: Panel Discussion with Audience Q&A. Transcatheter Valve Therapies 2010. June 7, 2010. Invited Speaker: Coronary Sinus Mitral Annuloplasty Essentials: Anatomy, Mechanism, and Device Page 18 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Similarities and Differences. Transcatheter Valve Therapies 2010. June 7, 2010 Invited Faculty: Session IV: Coronary Sinus Mitral Annuloplasty:Will Coronary Sinus Annuloplasty Succeed? Panel Discussion with Audience Q&A. Transcatheter Valve Therapies 2010. June 7, 2010. Invited Faculty: Session VII: Percutaneous Mitral Valve Therapies: Controversial Issues. Transcatheter Valve Therapies 2010. June 7, 2010. Invited Speaker: Step-by-Step Closure of Paravalvular Mitral Leaks Transcatheter Valve Therapies 2010. June 8, 2010 Invited Faculty: Session VII: Percutaneous Mitral Valve Therapies: Controversial Issues. Transcatheter Valve Therapies 2010. June 7, 2010. Invited Faculty: Paravalvular Leak: Diagnosis and Treatment Workshop Transcatheter Valve Therapies 2010. June 8, 2010. Invited Faculty: Mitral Bioskills Sessions II. Transcatheter Valve Therapies 2010. June 8, 2010. Invited Speaker: Percutaneous Mitral Therapy with the Double Orifice Leaflet Repair Technique. Case Reviews. Transcatheter Valve Therapies 2010. June 8, 2010 Invited Speaker: Optimal Puncture Sites for LAA Occlusive Devices and Percutaneous Mitral Edge to Edge Repair Transcatheter Valve Therapies 2010. June 9, 2010. Invited Speaker/Faculty: Hands on Transseptal Lab - Step by Step Technique Transcatheter Valve Therapies 2010. June 9, 2010 Invited Speaker: LAA and Transseptal Bioskills Session: Complex Case Presentations. Transcatheter Valve Therapies 2010. June 9, 2010 Invited Speaker. Update on MitraClip Procedure. Case selection and procedure details. Auckland, New Zealand, June 14, 2010 Invited Speaker: Percutaneous Mitral Valve Repair with MitraClip: Deivce Overview, EVEREST Ii and High-Risk Registry Update. C3(Complex Cardiovascular Catheter Therapeutics) Advanced Endovascular and coronary intervention global summit. Baltimore Marriot Waterfront/Baltimore, MD. June 21st , 2010. Invited Speaker: Selection of Appropriate Techniques for Reduction of Mitral Regurgitation - Who is Suitable for Leaflet Repair?. iCi- Imaging in Cardiovascular Interventions 2010. Frankfurt, Germany, July 7, 2010. Invited Speaker:Suitability for Mitral Valve Repair.. iCi- Imaging in Cardiovascular Interventions 2010. Frankfurt, Germany, July 7, 2010. Invited Faculty; Chairman: Catheter Treatment of Mitral Regurgitation..iCi-Imaging in Cardiovascular Interventions. Frankfurt, Germany.July 7, 2010. Invited Facultyr:Chairperson: Session: Mitral Valvuloplasty and Mitral Valve Repair.. iCi- Imaging in Cardiovascular Interventions 2010. Frankfurt, Germany, July 7, 2010. Invited Speaker: How to Manage Difficult MitraClip Situation. CSI 2010-Congenital and Structural Interventions. Frankfurt, Germany, July 8, 2010. Invited Faculty: Chairperson: Session; Left Atrial Appendage. Frankfurt, Germany, July 8, 2010. Invited Speaker: Watchman LAA Occluder Procedural Technique. Frankfurt, Germany, July 9, 2010 Page 19 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: Update on PFO clinical trials. CSI 2010-Congenital and Structural Interventions. Frankfurt, Germany, July 8, 2010 Invited Faculty: Chairperson in the Session: Mitral Regurgitation. CSI 2010-Congenital and Structural Interventions. Frankfurt, Germany, July 10, 2010 Invited Speaker: State of Art-Catheter Based Double Orifice Repair. CSI 2010-Congenital and Structural Interventions. Frankfurt, Germany, July 10, 2010 Invited Faculty: Chairperson: Devices for Heart Failure Management.CSI 2010-Congenital and Structural Interventions. Frankfurt, Germany, July 10, 2010 Invited Speaker: Devices for Monitoring Heart Failure Treatment. CSI 2010-Congenital and Structural Interventions. Frankfurt, Germany, July 10, 2010. Invited Speaker: Guided Delivery System. Frankfurt, Germany, July 10, 2010 Invited Speaker: Intra-Procedural Monitoring of PFO Closure: PICS & AICS. Sheraton Hotel, Chicago. July 17th. 2010. Invited Speaker/Faculty: Systemic & Pulmonary veins and paravalvular leaks: Aortic & Mitral Sessions. July 17th. 2010. Invited Speaker/Faculty: Atrial Appendage closure and Atrial Fibrillation: An update. The Head to Toe Meeting at the Meritage Hotel. NAPA, CA. July 16, 2010. Invited Speaker/Faculty: Percutaneous Mitral Valve Repair: Tackling the Mitral Valve Leaflets. Head to Toe Meeting, NAPA, CA. July 16, 2010. Invited Speaker/Faculty: Panelist Live Cases. PICS & AICS. Sheraton Hotel, Chicago, July 20th. 2010. Invited Speaker/Faculty: Trans-septal puncture: Technique, complications: prevention & management, July 20th. 2010. Invited Speaker/Faculty: Interventional Options for the Mitral Valve: The Percutaneous MitraClip ? Rocky Mountain Valve Symposium. July 22, 2010. Invited Speaker/Faculty: Which Technology and Approach is Best? Are we abandoning Outcomes in Favour of Invasiveness. Debate with Faculty. Rocky Mountain Valve Symposium. July 22, 2010. Invited Speaker/Faculty: Case Presentaton for Percutaneous Mitral Valve Repair. Tips and Tricks in Complex Interventional Cardiovascular Therapy(CICT). Fairmont Hotel, San Francisco. July 31, 2010. Invited Speaker: Mitral Valve Therapies and EVEREST data" Asian Pacific Great Minds Symposium, Singapore, August 21, 2010. Invited Speaker: Left Atrial Appendage Occlusion for the prevention of stroke. CVIT2010( Japanese Association of Cardiovascular Interventions and Therapeutics. Sendai. August 22, 2010 Invited Speaker;(Sateliite seminar); Percutaneous Mitral Valve Repair Using the Mitra Clip: An Alternative for Open Heart Surgery. CVIT2010( Japanese Association of Cardiovascular Interventions and Therapeutics. Sendai. August 23, 2010 Invited Faculty: Session: Innovations in Structural and Valvular Heart Disease( the hottest topic of the year): Discussant. TCT2010(Transcatheter Therapeutics), September 21, 2010. Invted Speaker: Trans-Septal Crossing: An overview of New Approaches to Transseptal Catheterization(RF, Jugular Approaches, and More). TCT2010(Transcatheter Therapeutics), September Page 20 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 21, 2010. Invited Speaker. Emerging Directions: The Mitral Valve Clip. TCT2010(Transcatheter Therapeutics), September 21, 2010. Invited Faculty: Discussant, Session 3: The Mitral Valve: Registered Cardiovascular Invasive Specialists(RCIS) Review Course. TCT2010(Transcatheter Therapeutics), September 21, 2010. Invited Faculyt: Moderator:Left Atrial Appendage Closure: Indications, Devices, and Techniques. Options to Exclude the Left Atrial Appendage. TCT2010(Transcatheter Therapeutics), September 22, 2010. Invited Faculty: Discussant: Left Atrial Appendage Closure: Indications, Devices, and Techniques, The Watchman. TCT2010(Transcatheter Therapeutics), September 22, 2010. Invited Speaker: Interim results form CAP, and future regulatory studies. TCT2010(Transcatheter Therapeutics), September 22, 2010. Invited Faculty: Discussant: Left Atrial Appendage Closure: Indications, Devices, and Techniques,Session IV: Technical considerations and new directions. TCT2010(Transcatheter Therapeutics), September 22, 2010. Invited Faculty: Discussant: Left Atrial Appendage Closure: Indications, Devices, and Techniques, The Watchman. TCT2010(Transcatheter Therapeutics), September 22, 2010. Invited Speaker: Case Presenter Left Atrial Appendage Occlusion tips and tricks; how to avoid complications ( case-based reviews ).. TCT2010(Transcatheter Therapeutics), September 22, 2010. Invited Speaker: The MitraClip Option for Functional MR III: How Much Does MR Need to be Reduced for Clinical Benefit? TCT2010(Transcatheter Therapeutics), September 22, 2010. Invited Faculty: Live Case Co-Moderator: How to Treat Theater: Structural Heart Disease I. Live cases: Transcatheter Valve Therapies I. TCT2010(Transcatheter Therapeutics), September 23, 2010. Invited Faculty: Discussant: How ot Treat Theater: Structural Heart Disease I: Transcatheter Valve Therapies II. TCT2010(Transcatheter Therapeutics), September 23, 2010. Invited Speaker: Patient selection, Technique Evolution and Clinical Outcomes with Percutaneous Mitral Valve Repair: New Insights from the EVEREST Registries and Randomized Trials. TCT2010(Transcatheter Therapeutics), September 23, 2010. Invited Faculty: Discussant. How to Treat Theater: Structural Heart Disease I: Transcatheter Valve Therapies II TCT2010(Transcatheter Therapeutics), September 23, 2010. Invited Faculty: Discussant: Emerging Late Breaking Data: the EVEREST II Trial. TCT2010(Transcatheter Therapeutics), September 23, 2010. Invited Speaker: Has EVEREST II Demonstrated 3—Day Safety for the MitraClip ?TCT2010(Transcatheter Therapeutics), September 23, 2010. Invited Faculty; Discussant: Mystifying Hemodynamics in Structural Heart Disease Interventions TCT2010(Transcatheter Therapeutics), September 24, 2010. Invited Speaker. Hemodynamics of Percutaneous Mitral Valve Interventions.TCT2010(Transcatheter Therapeutics), September 24, 2010. Invited Faculty:.Discussant: Imaging Guidance for Transcatheter Valve Interventions: Session III. Transcatheter Mitral Repair I: The Mitral Clip. TCT2010(Transcatheter Therapeutics), September 24, 2010. Page 21 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: Imaging Guidance to Select the Appropriate Repair.TCT2010(Transcatheter Therapeutics), September 24, 2010. Patient for Mitral Clip Invited Speaker(Debate): Sponsored by the British Cardiovascular Intervention Society: This House Believes: Percutaneous MV Repiar Can Achieve as Good or Better Clincal Outcomes Compared to Surgical Repair !. TCT2010(Transcatheter Therapeutics), September 24, 2010. Invited Speaker( Cardiology Grand Rounds) Percutaneous Mitral Valve Repair: Not just a dream but a true reality. University of Chicago Medical Center, Chicago, October 1, 2010 Invited Faculty: Invited Speaker: St Jude Medical Symposium: Transcatheter Aortic Valve Implantation: An Overview. October 9, 2010 Invited Speaker: Mitral Valve Therapies: From EVOLUTION to EVEREST. VIVA 10, Las Vegas, October 18, 2010. Invited Speaker: A Glimpse into the Future: Percutaneous Mitral and Aortic Devices on the Horizon. VIVA 10, Las Vegas, October 18, 2010. Invited Speaker. Percutaneous Mitral Valve Repair, The Leaflet Approach. Endovascular & Coronary Revascularization in Seoul (ENCORE SEOUL 2010). November 6, 2010, Seoul, Korea Invited Speaker. Left Auricle Appendage Closure:Actual Status. Endovascular Revascularization in Seoul (ENCORE SEOUL 2010). November 6, 2010, Seoul, Korea. & Coronary Invited Faculty. Panelist: Lunch Symposium on Contrast Induced Nephropathy. Endovascular & Coronary Revascularization in Seoul (ENCORE SEOUL 2010). November 5, 2010, Seoul, Korea. Invited Faculty. Panelist: Live Session 3. Endovascular & Coronary Revascularization in Seoul (ENCORE SEOUL 2010). November 5, 2010, Seoul, Korea Invited Faculty. Panelist Session: Transcatheter Aortic Valve Implantation.. Endovascular & Coronary Revascularization in Seoul (ENCORE SEOUL 2010). November 6, 2010, Seoul, Korea. Invited Speaker: Cardiology Grand Rounds: Montreal Heart Institute. Percutaneous Mitral Valve Repair using the MitraClip Device. November 11, 2010 Invited Speaker: Cardiology and Surgery discussion: Patient screening and steps of the MitraClip Procedure. November 11, 2010 Invited Speaker. Cardiology and Cardiac Surgery Grand Rounds. Sunny Brook Health Medical Center, Toronto. Percutaneous Mitral Valve Repair using the MitraClip: Clinical Update. November 12, 2010. Invited Speaker: Percutaneous Mitral Valve Repair using the MitraClip: A true reality. AMI2010( Acute myocardial infarxtion 2010): New Frontiers in Cardiology. November 13, 2010. Invited Speaker: Percutaneous closure of the left atrial appendage: Procedural steps & Tips and Tricks to avoid complications. PREVAIL Investigator Meeting. Hyatt Regency, Chicago, November 13, 2010 Invited Speaker: Strategies to recruit patients for the Study. PREVAIL Investigators Meeting, Hyatt Regency, Chicago, November 13, 2010. Invited Speaker: Elizabeth’s Choice: The MitraClip. Excellence in Interventional Cardiology meeting at Fairmont Chateau, Whistler Resort. Whistler, Canada. Dec 4, 2010. Page 22 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: The MitraClip, So easy Even a Surgeon Can Do it. Dallas Leipzig International Valve 2010. Dallas, Texas, US, December 9, 2010. Invited Speaker: Mitral Valve Case Studies: Dallas Leipzig International Valve 2010. Dallas, Texas, US, December 9, 2010. Invited Speaker: “EBM about Percutaneous mitral valve repair” CULT 2011(Cardiac interventions Under the Leaning Tower around Percutaneous valve procedures). Stazione Leopolda, Pisa, Italy, January 27, 2011. Invited Faculy: Chairperson in Live TAVI session. India Live 2011: A national course on Percutaneous Cardio-Vascular Interventions. Hotel Taj Lands End, Bandra, Mumbai. February 18, 2011 Invited Speaker: Percutaneous Mitral Valve Interventions. India Live 2011: A national course on Percutaneous Cardio-Vascular Interventions. Hotel Taj Lands End, Bandra, Mumbai. February 19, 2011 Invited Speaker. New Approaches to trans-septal catheterization. India Live 2011: A national course on Percutaneous Cardio-Vascular Interventions. Hotel Taj Lands End, Bandra, Mumbai. February 19, 2011 Invited Faculy; Chairperson of the Session: Emerging Therapy Conclave:Mitral Valve. India Live 2011: A national course on Percutaneous Cardio-Vascular Interventions. Hotel Taj Lands End, Bandra, Mumbai. February 19, 2011 Invited Faculty: Chairperson; Structural Heart disease symposium. India Live 2011: A national course on Percutaneous Cardio-Vascular Interventions. Hotel Taj Lands End, Bandra, Mumbai. February 19, 2011 Invited Faculty: Live case Operator.. China Interventional Therapeutics(CIT), China National Convention Center, Beijing, China, March 17, 2011 Invited Faculty: Live Case discussant; Case session 8: LM bifurcation and TAVI role. China Interventional Therapeutics(CIT), China National Convention Center, Beijing, China, March 17, 2011 Invited Speaker: Percutaneous Pulmonic Vlve Replacement: An Option for Filed Conduits to the Pulmonic Artery. China Interventional Therapeutics(CIT), China National Convention Center, Beijing, China, March 18, 2011 Invited Faculty: Panel Discussant with audience on Structural Heart disease symposium part II. China Interventional Therapeutics(CIT), China National Convention Center, Beijing, China, March 18, 2011 Invited Faculty: Moderator, Fires Report Investigations China Interventional Therapeutics(CIT), China National Convention Center, Beijing, China, March 18, 2011 Invited Speaker: Edge to Edge Mitral Valve Repair: Current Status of the MitraClip Porcedure. China Interventional Therapeutics(CIT), China National Convention Center, Beijing, China, March 17, 2011 Invited Speaker. MitraClip: Is It Possible? What Do Surgeons Think? Case Based Studies on Valvular Heart Disease symposium sponsored by Mayo Clinic Cardiovascular Division. New Orleans Marriot at the Convention Center. New Orleans, April 2, 2011. Invited Speaker: Structural Heart Tools, Tips and Tricks. Access to Closure:Interventional Cardiology Fellows Symposium. Royal Sonesta, New Orleans, April 2, 2011. Invited Faculty: Co Chairman: ACC i2 Symposium;Session Title: the MV disease and transcatheter interventions; case reviews. New Orleans, April 3, 2011. Invited Speaker: Current Status of LAA Occlusion: ACC i2 Symposium. New Orleans, April 3, 2011. Invited Faculty: Co Chair: ACC i2 Symposium: Session: Imaging Before, During and After Mitral Valve Procedures. New Orleans, April 4, 2011. Page 23 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: Evaluation and Management of Unstable Angina/NSTEMI; ACC Core-curriculum Lecture. New Orleans, April 5, 2011. Invited Faculty: Co Chairperson of ACC core curriculum lecture: Session: Acute and Chronic Coronary artery disease., ACC, New Orleans, April 5, 2011. Invited Faculty: ACC Panelist: Meet the Experts entitled Optimum Reperfusion Approach to STEMI, New Orleans, April 5, 2011. Invited Speaker: Percutaneous Mitral Valve Repair: Indications and Technique. Global Summit on Interventions and Innovations(GI2 summit) BRAZIL 2011. Sao Paulo, Brazil, April 13, 2011. Invited Faculty: Live Case First Session. Global Summit on Interventions and Innovations(GI2 summit) BRAZIL 2011. Sao Paulo, Brazil, April 14, 2011 Invited Speaker: Can Left Atrial Appendage Closure Become an Important Therapy for Atrial Fibrillation Patients? Global Summit on Interventions and Innovations(GI2 summit) BRAZIL 2011. Sao Paulo, Brazil, April 14, 2011 Invited Speaker: Optimal clinical applications for the MitraClip and Other Devices Global Summit on Interventions and Innovations(GI2 summit) BRAZIL 2011. Sao Paulo, Brazil, April 14, 2011 Invited Speaker: Transcatheter Implantable Monitoring Devices for Heart Failure Global Summit on Interventions and Innovations(GI2 summit) BRAZIL 2011. Sao Paulo, Brazil, April 15, 2011 Invited Speaker: Perspectives from PARTNER: Striking Observations and Implications Global Summit on Interventions and Innovations(GI2 summit) BRAZIL 2011. Sao Paulo, Brazil, April 15, 2011Invited Panelist Live Session 3 Global Summit on Interventions and Innovations(GI2 summit) BRAZIL 2011. Sao Paulo, Brazil, April 15, 2011. Invited Speaker: MitraClip Therapy: indications and results. Los Angeles Society of Echocardiography meeting. Good Samaritan Hospital, April 16, 2011. Invited Speaker: Patient Selection for Percutaneous Mitral Valve Repair: What is Possible. Annual Concepts in Contemporary Medicine Symposium (CCC 2011), Hilton of Americas, Houston, Texas, April 28, 2011. Invited Faculty: Panelist: Live case demonstration: structural heart disease intervention. Annual Concepts in Contemporary Medicine Symposium (CCC 2011), Hilton of Americas, Houston, Texas, April 28, 2011. Invited Speaker: Interventional Procedures in Women: Gender Differences. 5th Annual Women & Ischemic Heart Disease Symposium. Cedars Sinai Medical Center. April 29, 2011. Invited Speaker; Keynote Lecture: Structural Heart Interventions in the Cath Lab: The next frontier; RCIS course at the annual Society of Coronary Angiography and Intervention meeting (SCAI). May 6, 2011. Invited Speaker: Overview of the EVEREST II trial. Annual Society of Cardiac Angiography & Intervention Meeting(SCAI), Baltimore, May 7, 2011 Invited Faculty. Co-chairperson. Mitral Valve Interventions session . Annual Society of Cardiac Angiography & Intervention Meeting(SCAI), Baltimore, May 7, 2011 Invited Speaker: PFO and ASD closure : invited lecture in the structural heart disease primer. Annual Society of Cardiac Angiography & Intervention Meeting(SCAI), Baltimore, May 7, 2011 Invited Speaker: Left Atrial Appendag Occlusion : invited lecture in the structural heart disease primer. Annual Society of Cardiac Angiography & Intervention Meeting(SCAI), Baltimore, May 7, 2011 Page 24 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: The Challenge of Acquiring New Technical Skills After Fellowship at the Early Career Interventionalist Symposium. Annual Society of Cardiac Angiography & Intervention Meeting(SCAI), Baltimore, May 7, 2011 Invited Speaker: WATCHMAN LAA Closure: The Cedars Sinai Experience. Symposium sponsored by Boston Scientific Symposium at Pavillion Ledoyen at Paris, May 17, 2011 Invited Faculty: Co-chairman: Session: Edge to edge mitral valve repair: clinical, hemodynamic and echocardiographic evaluation. EUROPCR 2011 at Palais des congress Paris, May 17, 2011 Invited Faculty: Panelist on a Plenary session on Percutaneous intervention for mitral regurgitation. EuroPCR 2011, Palais des congress, Paris May 18, 2011 Invited Faculty: Co-chairperson: Percutaneous mitral valve repair therapy: building a successful programme. EuroPCR2011, Palais des congress, Paris May 18, 2011 Invited Speaker: Left atrial appendage closure and the PROTECT AF trial: results at 1500 patient-years of follow up. EuroPCR 2011, Palais des congress, Paris, May 20, 2011. Invited Speaker: Advances in Mitral Valve Disease. 2nd Annual Highlights in Cardiovascular Therapies: A contemporary course for cardiac and vascular specialists. Grand Hyatt, Seattle. May 20, 2011. Invited Speaker: Percutaneous Coronary Interventions for Heart failure, Stem cells and Valves, Optimal Care and New Therapies for Advanced Heart Disease Symposium.Bakersfield, May 21, 2011. Invited Speaker: Update on MitraClip Therapy. 5th Oriental Congress of Cardiology (OCC 2011) at Shanghai International Convention Center, Shanghai, China, May 30, 2011. Invited Speaker. Update on percutaneous cardiac interventions. Delco Symposium, Santa Barbara. CA June 1, 2011. Invited Speaker: Bioskills lab on Mitral Valve anatomy and interventions. Transcatheter Valve Therapies Meeting(TVT 2011). Vancouver, June 5, 2011 Invited Speaker: Mitral Valve Sessions: Edited Taped Case.. Transcatheter Valve Therapies.Meeting(TVT 2011). Vancouver, June 6, 2011 Invited Speaker: Transseptal Workshop. Targeted Transseptal with TEE for Mitral Valve interventions. Transcatheter Valve Therapies(TVT 2011). Vancouver, June 7, 2011 Invited Faculty: Assist in Live case using Pulmonic Valve. Transcatheter Valve Therapies(TVT 2011), Vancouver, June 7, 2011. Invited Speaker: Live Taped case of LAA occlusion using the Watchman Device. Transcatheter Valve Therapies(TVT 2011). Vancouver, June 7, 2011. Invited Speaker/Coarse Directors: Transseptal course. Lennox Hill Hospital, June 10-11, 2011. Invited Speaker: Percutaneous Mitral Devices: Can we surgical outcomes. 2011 Live Symposium of Complex Coronary and Vascular Cases, New York, June 16, 2011. Invited Faculty: Panelist: Live Symposium of Complex Coronary and Vascular Cases. Mount Sinai Hospital, New York, June 17, 2011. Invited Faculty : Chairperson in the session:Imaging in mitral valve interventions. iCiFrankfurt 2011(Imaging in Cardiovascular Interventions. June 22, 2011 Invited Faculty : Long-term Echocardiographic Follow-up After MitraClip. iCiFrankfurt 2011(Imaging in Cardiovascular Interventions. June 22, 2011 Page 25 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: Intraprocedural Guidance for the Watchman Device. iCi Frankfurt 2011(Imaging in Cardiovascular Interventions), Frankfurt June 22, 2011 Invited Faculty: Chairperson: Session on Left atrial appendage iCi Frankfurt 2011(Imaging in Cardiovascular Interventions), Frankfurt June 22, 2011 Invited Speaker ; The Circulite System-a Partial Circulatory Support Device. 2011(Congenital & Structural Interventions),Frankfurt, June 23, 2011 CSI Frankfurt Invited Speaker ;Update on the Watchman Trials.. CSI Frankfurt 2011(Congenital & Structural Interventions), Frankfurt, June 23, 2011 Invited Speaker ; How to manage difficult cases of left atrial appendage occlusion.. CSI Frankfurt 2011(Congenital & Structural Interventions), Frankfurt, June 24, 2011 Invited Speaker ; “Let the Battle Commence”, Low surgical risk – Catheter technology versus surgery_ In favour of Catheter therapy.. CSI Frankfurt 2011(Congenital & Structural Interventions), Frankfurt, June 25, 2011. Invited Speaker How to do Transseptal puncture- Alternate approaches.. CSI Frankfurt 2011(Congenital & Structural Interventions), Frankfurt, June 25, 2011 Invited Faculty: Multidisciplinary Advisory Summit : MitraClip Therapy. Chicago. June 27, 2011. Invited Speaker: Evolution of trans-catheter heart technology The 1st Manchester Adult Structural Heart Intervention Meeting. June 28, 2011. Invited Speaker: Case Examples: Scope of MitraClip. The 1st Manchester Adult Structural Heart Intervention Meeting. June 28, 2011. Invited Speaker: The Cedars Sinai LAA learning curve: lessons for SHD intervention.The 1st Manchester Adult Structural Heart Intervention Meeting. June 28, 2011. Invited Speaker: Cardiac surgery and interventional cardiology grand rounds: Percutaneous Mitral Valve Repair with the MitraClip System. St Paul’s Hospital, Vancouver, Canada. June 30, 2011 Invited Speaker/Course Director Gore® Helex® Device: A Physician Perspective. Atrial Septal defect Closure Course, Cedars Sinai Medical Center, Los Angeles, CA July 7, 2011 Invited Speaker/Course Director: Clinical Data Overview of the Helex Septal Occluder. Atrial Septal defect Closure Course, Cedars Sinai Medical Center, Los Angeles, CA July 8, 2011 Invited Speaker/Course Director: Hemodynamics/Rim assessment/Imaging: Atrial Septal defect Closure Course, Cedars Sinai Medical Center, Los Angeles, CA July 8, 2011 Invited Speaker. New Mitral Valve Techniques(30minutes). NMCSDs Integrative Imaging Symposium, Naval Hospital, Camp Pendleton, San Diego, July 10, 2011. Invited Speaker: Structural Heart Disease Imaging( 30 minutes). NMCSDs Integrative Imaging Symposium. Naval Hospital, Camp Pendleton, San Diego, July 10, 2011. Invited Speaker: CLOSURE I Results Overview. Pediatric and Adult Interventional Cardiac Symposium( PICS-AICS 2011), Westin Boston Waterfront, Boston, July 23, 2011 Invited Speaker:LAA Closure: Pre-selection, Guidance of Procedure & Follow up(15 minutes). Pediatric and Adult Interventional Cardiac Symposium (PICS -AICS 2011). Westin Boston Waterfront. July 24, 2011. Page 26 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: Update on Percutaneous Mitral Valve Repair. Pediatric and Adult Interventional Cardiac Symposium( PICS-AICS 2011), Westin Boston Waterfront, Boston, July 25, 2011 Invited Speaker: Update on MitraClip . The 5th Qianjiang International Cardiovascular Congress, Hangzhou, China, July 29, 2011 Invited Speaker: Nightmare in the cath lab-case presentation on percutaneous valve complications(20 minutes). Great minds symposium, Grand Hyatt, Hong Kong. July 30, 2011 Invited Speaker: Debate: Mitraclip versus Surgery-for the motion. Great Minds Symposium, Grand Hyatt, Hong Kong, July 30, 2011. Invited Speaker: Pathology of the Mitral Valve & Overview of the Transcatheter Mitral Valve Therapies. China Heart Conference(CHC), Beijing, August 13, 2011. Invited Speaker: Transcatheter Closure of PFO. China Heart Conference(CHC), Beijing, August 13, 2011. Invtied Speaker: Percutaneous Treatment of Mitral Valve using the MitraClip. Innovation in Cardiology 2011, Gurgeon, New Delhi, August 14, 2011 Invited Speaker Percutaneous Mitral Valve Therapy: Is Repair feasible or is Replacement the Best Option?. ACVS Hyderabad, India August 19, 2011. Invited Speaker: Left Atrial Appendage Closure: Review of the Evidence. ACVS, Hyderabad, India, August 20, 2011. Invited Speaker: Epworth Health Care Cardiac Sciences Clinical Institute Symposium (30th year anniversary). Percutaneous intervention for mitral regurgitation. Park Hyatt Melbourne, Melbourne Sept 10th 2011. Invited Speaker: Epworth Health Care Cardiac Sciences Clinical Institute Symposium (30th year anniversary). If there is hole just close it. Park Hyatt Melbourne, Melbourne Sept 10th 2011. Invited Speaker. PCI in Heart Failure: Valves and Stem Cells. Optimal Care and New therapies for Advanced Heart Disease. Hyatt Regency, Newport Beach, CA. Sept 17, 2011. Invited Speaker: Transcatheter Mitral Valve Repair and Replacement. Scripps’ 22nd Annual Coronary Interventions, Hilton La Jolla, La Jolla, California, Sept 22, 2011 Invited Speaker: Evening symposium for Alfred Hospital. Advances in structural heart disease interventions. Melbourne. September 27, 2011 Invited Speaker: Cardiology Grand rounds: Percutaneous closure of the left atrial appendage as an alternative to Coumadin for prevention of stroke. Epworth Hospital. Sept 28, 2011 Invited Speaker: MitraClip: Lesson learned from the EVEREST II Trial. Kuala Lumpur Valve Summit 2011. Hilton Kuala Lumpur, Malaysia, October 6, 2011 Invited Speaker: Live in Box: MitraClip Implantation. Kuala Lumpur Valve Summitt 2011, Hilton Kuala Lumpur, Malaysia, October 6, 2011. Invited Speaker: :Lunch Symposium: The critical role of TEE for successful LAA closure. Kuala Lumpur Valve Summitt 2011, Hilton Kuala Lumpur, Malaysia, October 7, 2011. Invited Speaker: Lunch Symposium: New generation Direct Thrombin Inhibitors(Dabigatran)- Alternative to LAA Occluders? Kuala Lumpur Valve Summitt 2011, Hilton Kuala Lumpur, Malaysia, October 7, 2011. Invited Speaker: PCI for Heart Failure, Stem Cells and Valves. Optimal Care And New Therapies For Advanced Heart Disease, Las Vegas, Nevada, October 22, 2011 Page 27 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: LAA Closure With the Watchman Device: Tips and Tricks. American Heart Association Meeting. Orlando, Florida, November 15, 2011. Invited Faculty: Moderator LAA closure: Step by Step. LAA workshop 2011 in Frankfurt, November 19,2011 Invited Speaker: 2D and 3D TEE Before, During and After LAA Closure . LAA workshop 2011, in Frankfurt, November 19,2011 Invited Speaker: We now Have new Drugs – do we Still Need LAA Closure at all? LAA workshop 2011, in Frankfurt, November 19,2011 Invited Faculty: Live case operator. LAA workshop 2011 in Frankfurt, November 19,2011 Invited Speaker: Coherex WaveCrest LAA Occluder: Step by step. LAA workshop in Frankfurt, November 19,2011 Invited Speaker: Case presentation; a difficult case of Watchman Device. LAA workshop 2011 in Frankfurt, November 19, 2011 Invited Speaker, Update on TAVI and MitraClip. State of the Art Cardiovascular Medicine Conference. Hyatt Regency Mission Bay, Organized by University of San Diego. December 2, 2011 Invited Speaker: Advances in percutaneous structural heart interventions. Medicor Cardiovascular disease symposium. Izola December 3, 2011 Invited Speaker: : Intevencionismo en cardopatia estructural:Oclusionde la orejuela izquierda en Fibrilacion Auricular. Annual Congress of Mexican Society of Interventional Cardiology (SOCIME), Puebla, Mexico, December 10, 2011 Invited Speaker: INTERVENTIONAL TREATMENT OF MITRAL INSUFFICIENCY WITH MITRAL REPAIR – MITRACLIP.Annual Congress of Mexican Society of Interventional Cardiology (SOCIME), Puebla, Mexico, December 10, 2011 Invited Faculty: Panelist for Live case demonstration. Asia PCR Singapore Live. Singapore, Jan 13, 2012 Invited Faculty: Panelist : Mini debate: Perspectives on PCI in patients with high risk acute coronary syndrome. Asia PCR Singapore Live. Singapore, Jan 13, 2012 Invited Faculty: Chairperson: Transcatheter Mitral Interventions. Asia PCR Singapore Live. Singapore, Jan 13, 2012 Invited Speaker. Technical challenges and complications of mitral clip procedures. Asia PCR Singapore Live. Singapore, Jan 13, 2012 Invited Faculty: Chairperson; Left atrial appendage closure for atrial fibrillation patients. Asia PCR Singapore Live. Singapore, Jan 13, 2012 Invited Speaker: Overview of LAA closure devices and outcomes. Asia PCR Singapore Live. Singapore, Jan 13, 2012 Invited Faculty: Panelist: In session How to treat ? Asia PCR Singapore Live. Singapore, Jan 14, 2012 Invited Faculty: Panelist: Live case demonstration. Asia PCR Singapore Live. Singapore, Jan 14, 2012 Page 28 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Faculty: Panelist; My vision of the future of non coronary interventions. Asia PCR Singapore Live. Singapore, Jan 13, 2012 Invited Speaker: Chairperson: Mitral Valve Symposium. Second National Heart Valve Summit, New Delhi January 27, 2012 Invited Speaker: Percutaneous approach to MV repair- Edge to edge Mitral leaflet repair with Mitraclip Technique. Second National Heart Valve Summit, New Delhi January 28, 2012 Invited Speaker: Direct annuloplasty devices : Mitralign Quantum Core etc.. IInd National Heart Valve Summit, New Delhi January 28, 2012 Invited Speaker: LA appendage occlusion – Technique with case demonstration. IInd National Heart Valve Summit, New Delhi January 28, 2012 Invited Speaker: WATCHMAN Trial & LIVE IN BOX LAA Closure,. IInd National Heart Valve Summit, New Delhi January 27, 2012 Invited Speaker: Does M.V. clipping effect outcome for subsequent valve replacement?. IInd National Heart Valve Summit, New Delhi January 27, 2012 Invited Speaker: LIVE/ LIVE INBOX MITRA- CLIP. IInd National Heart Valve Summit, New Delhi January 27, 2012 Invited Speaker: Transcatheter Pulmonic Valve Implantation: Indications, Treatment Options, and Procedure, Scripps Clinic’s Structural Heart Intervention and Imaging conference. San Diego Marriot, La Jolla, California. February 2, 2012 Invited Speaker:The MitraClip Procedure: How, in Whom, and Why Scripps Clinic’s Structural Heart Intervention and Imaging conference. San Diego Marriot, La Jolla, California. February 3, 2012 Invited Speaker: Percutaneous Mitral Valve Repair and Replacement. Tremblant Interventional Cardiology 2012, Tremblant, Canada, February 4, 2012 Invited Speaker: PERCUTANEOUS APPROACH TO MITRAL VALVE REPAIR: EDGE-TO-EDGE MITRAL LEAFLET REPAIR. CRT 2012, Omni Shoreham Hotel, Washington DC, February 5, 2012 Invited Faculty: Panelist:: IS Percutaneous Valve Repair Ready for Prime Time? For Whom?. CRT 2012, Omni Shoreham Hotel, Washington DC, February 5, 2012, Invited Speaker: Advances in percutaneous treatment of structural cardiac defects. Emergency department grand rounds. Cedars Sinai Medical Center, Los Angeles, February 9, 2012 Invited Speaker: MitraClip Overview; EVEREST RCT and I High Risk Registry. Innovation in Mitral Valve Interventions. Shangri La Hotel, Sydney, Australia, February 18, 2012 Invited Speaker: MitraClip Case Reviews. Innovation in Mitral Valve Interventions. Shangri La Hotel, Sydney, Australia, February 18, 2012 Invited Speaker: Cardiology Grand rounds: Percutaneous Devices for the prevention of Cardioembolic stroke: Clinical evidence versus common sense. Cedars Sinai Medical Center, February 21, 2012 Invited Speaker: Radial Vascular Access and Closure: Technique, Devices, and Complications. FellowsCourse. INDIA LIVE 2012, Taj Palace Hotel, New Delhi, February 23, 2012 Invited Speaker: Radial Vascular Access and Closure: Technique, Devices, and Complications. FellowsCourse. INDIA LIVE 2012, Taj Palace Hotel, New Delhi, February 23, 2012 Page 29 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: Stent Selection and Optimal Implantation Techniques with Case Reviews. Fellows Course. INDIA LIVE 2012, Taj Palace Hotel, New Delhi, February 23, 2012. Invited Faculty: Chairperson: Percutaneous Valve Therapies. INDIA LIVE 2012, Taj Palace,Hotel, New Delhi, February 24, 2012 Invited Faculty: Chairperson: Innovative therapies status report.. INDIA LIVE 2012, Taj Palace,Hotel, New Delhi, February 24, 2012 [nvited Speaker: Left Atrial Appendage Closure in the innovative therapies status report. INDIA LIVE2012, Taj Palace Hotel, New Delhi, February 24, 2012 Invited Chairperson: Lunch Session - How to Reduce Stroke Risk in Patients Who Can’t Tolerate Blood Thinners: 11th Dead Sea Symposium, Telaviv, Israel, February 29, 2012 Invited Speaker: A Case of LAA Occlusion, Demonstration and Comments: 11th Dead Sea Symposium, Telaviv, Israel, February 29, 2012[[ Invited Speaker: Tips and Tricks in LAA Occlusion: 11th Dead Sea Symposium, Telaviv, Israel, February 29, 2012 Invited Speaker: Results of the Pertinent Studies and Registries: 11th Dead Sea Symposium, Telaviv, Israel, February 29, 2012 Invited Speaker;.E-Clip for Ischemic Mitral Regurgitation. Meet the experts session at the Annual Meeting of the American College Cardiology, Chicago, March 24, 2012 Invited Faculty; Poster Discussant. i2 Symposium at the Annual Meeting of the American College ;lCardiology, Chicago, March 24, 2012. Invited Speaker; Pros and Cons of Closure of a patent foramen ovale for the prevention of stroke. i2 symposium of the Annual Meeting of the American College Cardiology. Chicago. March 25, 2012. Invited Speaker; Debate: Mitral E- clip is a reasonable option for the treatment of functional mitral regurgitation. Annual Meeting of the American College Cardiology. Chicago. March 25, 2012 Invited Speaker. MitraClip, best, worst and other complications. i2 Imaging Symposium at the Annual Meeting of the American College Cardiology, Chicago, March 25, 2012. Invited Faculty: MitraClip case in the box. i2 Symposium at the Annual Meeting of the American College Cardiology, Chicago, March 26, 2012. Invited Speaker; Case presentation of Left atrial appendage closure. i2 Symposium at the Annual Meeting of the American College Cardiology, Chicago, March 26, 2012. Invited Faculty: Panelist in the session;Anatomy and Transcatheter Therapy for the Structural Heart Interventionalist. i2 Symposium at the Annual Meeting of the American College Cardiology, Chicago, March 26, 2012. Invited Speaker: Left atrial appendage closure. Boot camp for fellows at the i2 Symposium at the Annual Meeting of the American College Cardiology, Chicago, March 26, 2012 Invited Faculty: Discussant Structural II in the SOLACI session on Coronary and Congenital Interventions.GI² - Global Summit in Innovations in Interventions, São Paulo, Brazil. on April 11th 2012. Invited Speaker: Panelist for the Live cases. GI² - Global Summit in Innovations in Interventions, São Paulo, Brazil, April 12th 2012 Invited Speaker: Is Percutaneous Closure of the LAA Superior to Medical Treatment?GI² - Global Summit in Page 30 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Innovations in Interventions, São Paulo, Brazil. April 11th 2012 Invited Speaker: The MitraClip and Other Devices for Mitral Regurgitation, Indications, Technique & Outcomes. GI² - Global Summit in Innovations in Interventions, São Paulo, Brazil, April 12th 2012 Invited Speaker: New Devices for Heart Failure and Pulmonary Hypertension. GI² - Global Summit in Innovations in Interventions, São Paulo, Brazil, April 12th 2012 Invited Speaker: : Complications of Percutaneous Procedures II -- Complications of trans-septal approachesThe Big Apple meeting The Heart Valve Society of America. New York, April 13, 2012 Invited Speaker: : How to Implant a MitraClip.The Big Apple meeting The Heart Valve Society of America. New York, April 13, 2012 Invited Speaker: : Complex cases in review -- Clipping Functional MR with LV dysfunctionThe Big Apple meeting The Heart Valve Society of America. New York, April 13, 2012 Invited Speaker; Percutaneous Mitral Valve Repair – Patients to Avoid. PCIS-AICS (Pediatric & Adult Interventional Cardiac Symposium). Chicago, April 17, 2012 Invited Speaker; Debate: Against: Percutaneous Mitral Valve Therapies Should Be Restricted to Patients Not Suitable for Surgical Repair? PCIS-AICS (Pediatric & Adult Interventional Cardiac Symposium). Chicago, April 17, 2012 Invited Speaker:: "Percutaneous Repair of Mitral Regurgitaton-Another Treatment Option in the Cath Lab". Antelope Valley hospital Symposium. Hellenic Center, Lancaster, CA, April 21, 2012 Invited Speaker: Mitral Insufficiency Percutaneous Treatment. 61st International Congress of The European Society for Cardiovascular & Endovascular Surgery. Dubrovnik, Croatia, April 27, 2012 Invited Speaker: Mitral Insufficiency Percutaneous Treatment. 61st International Congress of The European Society for Cardiovascular & Endovascular Surgery. Dubrovnik, Croatia, April 27, 2012 Invited Speaker. Structural Heart Disease Interventions. Fellows Course in the 61st International Congress of The European Society for Cardiovascular & Endovascular Surgery. Dubrovnik, Croatia, April 27, 2012 Invited Speaker: Debate:Surgery Will Always Be Preferred For Some Patients with Mitral Regurgitation. American Association of Thoracic Surgery(AATS) Conference. San Francisco, CA, May 2, 2012 Invited Speaker; Transcatheter Treatment of Mitral Vavle Disease: New Devices and Concepts. American Association of Thoracic Surgery(AATS) Conference. San Francisco, CA, May 2, 2012 Invited Speaker: MitraClip a Life Changing Experience. Abbott Vascular Headquarters, Santa Clara, CA, May 3, 2012 ; Invited Faculty: Moderator of the Session entitled LAA closure Step by Step. CSI Focus Workshop LAA Asia-Pacific Singapore, May 5, 201212 Invited Speaker. Which Device for which appendage. CSI Focus Workshop LAA Asia-Pacific Singapore, May 5, 2012 Invited Speaker. Watchman Occluders in Patients with Contraindications for Anticoagulation. CSI Focus Workshop LAA Asia-Pacific Singapore, May 5, 2012. Invited Faculty: Moderator Mitral Valve Interventions. Society of Cardiac Angiography and Interventions Page 31 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI (SCAI) 2012 Las Vegas. May 10, 2012 Invited Speaker. The Role of MitraClip in functional mitral regurgitation. Society of Cardiac Angiography and Interventions(SCAI) 2012. Las Vegas. May 10, 2012. Invited Speaker. The ideal patient for Mitraclip. Society of Cardiac Angiography and Interventions(SCAI) 2012. Las Vegas. May 10, 2012. Invited Speaker. PCI for heart failure, valves and stem cells. Ventura, CA, May 12, 2012 Invited Speaker. Device therapy in atrial fibrillation , CRT, ablation and LAA closure in patients with congestive heart failure. CATCH UP-2012 New York Heart failure. New York-Presbyterian Hospital/Columbia University Med Ctr, New York, May 17, 2012 Invited Faculty: Discussant.Anatomical Dissection for structural heart disease therapy. Transcatheter Valve Therapeutics 2012 Seattle, June 2, 2012 Invited Speaker: Case Study: Concomitant Aortic Stenosis and MR. Transcatheter Valve Therapeutics 2012 Seattle, June 3, 2012 Invited Faculty: Role: Moderator. Mitral Session I. Mitral Regurgitation (MR) 2012: Major Themes and Intriguing Issues Stretching the (Anatomic) Reach of the MitraClip Transcatheter Valve Therapeutics 2012 Seattle, June 3, 2012 Invited Faculty: Discussant.Functional MR: Current and Future Therapies and an Update on the COAPT Trial Transcatheter Valve Therapeutics 2012 Seattle, June 4, 2012 Invited Speaker: Moderator.Preparing for the Future: Left Atrial Appendage Closure Transcatheter Valve Therapeutics 2012 Seattle, June 3, 2012 Invited Speaker: Forming the LAA Closure Multidisciplinary Team Transcatheter Valve Therapeutics 2012 Seattle, June 5, 2012 Invited Speaker: Targeted Transseptal with TEE: For the Mitral Valve Transcatheter Valve Therapeutics 2012 Seattle, June 5, 2012 Invited Faculty: Moderator. Mitral Session III. Failure of Surgical and Transcatheter Mitral Valve (MV) Therapies: Lessons for the Future Session II. Why the MitraClip Fails. Transcatheter Valve Therapeutics 2012 Seattle, June 5, 2012 Invited Speaker: Case Study 2: A Case When Imaging Saved the Day Transcatheter Valve Therapeutics 2012 Seattle, June 5, 2012 Invited Faculty: Moderator: LAA Session: Left Atrial Appendage Closure: Emerging Evidence, Techniques, and Devices Transcatheter Valve Therapeutics 2012 Seattle, June 5, 2012 Invited Speaker: The Watchman Clinical Studies Program (Warfarin Eligible): Perspectives, New Insights, and Future Directions. Transcatheter Valve Therapeutics 2012 Seattle, June 5, 2012 Invited Speaker: Taped Case Study: The Watchman Procedure Case. Transcatheter Valve Therapeutics 2012 Seattle, June 5, 2012 Invited Speaker: Tips and Tricks of LAA Occlusion Using the Watchman Device Transcatheter Valve Therapeutics 2012 Seattle, June 5, 2012 Invited Speaker: Tips and Tricks of LAA Occlusion Using the Amplatzer Cardiac Plug Transcatheter Valve Therapeutics 2012 Seattle, June 5, 2012 Invited Speaker: Complications of LAA Occlusion Devices: Frequency, Root Cause Analysis, and Prevention Through Device Design and Technique Transcatheter Valve Therapeutics 2012 Seattle, June 5, 2012 Page 32 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker: The MitraClip from EVEREST to clinical practice. 2012 Port Douglas Heart Meeting. June 8, 2012 Invited Speaker: Prediction regarding newer technologies, take-home messages and concluding remarks. Mitral Valve symposium, at the 2012 Port Douglas Heart Meeting, June 8, 2012 Invited Faculty: Moderator: Mitral valve symposium. 2012 Port Douglas Heart Meeting, June 8, 2012 Invited Speaker. The Future of structural heart disease interventions. 2012 Port Douglas Heart Meeting, June 9, 2012 Invited Speaker: MitraClip EVEREST to Real World. Brisbane Cardiac Imaging Meeting. Stanford Plaza Hotel, Brisbane, June 12, 2012 Invited Faculty: Panelist. Live case presentation: left main and bifurcation lesions. Mount Sinai Hospital, New York. June 15, 2012 Invited Faculty: Panelist. Live case presentations, chronic total occlusions. Mount Sinai Hospital, New York , June 15, 2012 Invited Speaker. Case presentation in the Mitral Valve session. Imaging in Cardiovascular Interventions (iCi Frankfurt 2012). Frankfurt, June 27, 2012 Invited Faculty. Chairsperson in the Mitral and Tricuspid Session. Imaging in Cardiovascular Interventions (iCi Frankfurt 2012). Frankfurt, June 27, 2012 Invited Speaker. The Watchman Device. Congenital and Structural Interventions (CSI Frankfurt 2012). Frankfurt, June 28, 2012 Invited Faculty. Chairperson, Session: LAA closure with the Watchman Occluder. Congenital and Structural Interventions (CSI Frankfurt 2012). Frankfurt, June 29, 2012 Invited Faculty. Chairperson. Session on Left Atrial Appendage Closure. Congenital and Structural Interventions (CSI Frankfurt 2012). Frankfurt, June 29, 2012 Invited Speaker. Long term Outcome after the Watchman Device. Congenital and Structural Interventions (CSI Frankfurt 2012). Frankfurt, June 29, 2012 Invited Speaker. Endocardial Solution is the way to go. Congenital and Structural Interventions (CSI Frankfurt 2012). Frankfurt, June 29, 2012 Invited Speaker. The Mitral Valve Apparatus: Influence of Echocardiography on Perioperative Clinical Decision Making: Degenerative Mitral Valve Disease. Pre-operative Considerations: When to Select a Percutaneous Approach. Annual American Society of Echocardiography Meeting (ASE 2012). National Harbor, Maryland. June 30, 2012 Invited Speaker. E-Valve Mitral Clip- Everest & Beyond. Rock Mountain Valve Symposium. Missoula, Montana. July 20, 2012 Invited Speaker. Ventricular Remodeling after Mitral Valve Intervention.. Rock Mountain Valve Symposium. Missoula, Montana. July 20, 2012 Invited Speaker. The Failed Clip: Hospice or Surgery. Rock Mountain Valve Symposium. Missoula, Montana. July 20, 2012 Invited Speaker. MitraClip-Clinical Outcome data Update. CICT(Complex Interventional Cardiovascular Therapy). Fairmont Hotel. San Franscisco. July 28, 2012. Page 33 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker. Taped Case on a Percutaneous Mitral Valve Repair using the MitraClip. China Heart Congress 2012, Beijing, China, August 11, 2012 Invited speaker. MitraClip results and procedure(overview). ACVS Hyderabad 2012. Hyderabad, INDIA. August 3, 2012 Invited speaker. LAA occlusion (overview of procedure and devices). ACVS Hyderabad 2012. Hyderabad, INDIA. August 3, 2012 Invited faculty. Live case guest operator using the Amplatzer cardiac plug device in Care hospital, Hyderabad, INDIA. August 4, 2012. Invited Speaker. Percutaneous Closure of Left Atrial Appendage: An Alternative to Long-term Antithrombotic Therapy in Patients with Atrial Fibrillation. China Heart Congress 2012, Beijing, China August 11, 2012 Invited Speaker. Percutaneous Mitral Valve Repair Using the MitraClip: From EVEREST to "Real World.. China Heart Congress 2012, Beijing, China August,11, 2012 Invited Speaker. Angiographic vs physiologic coronary assessment - the fame debate: Counter Point, The Angiogram is the best.. ANZET 2012. Brisbane, Australia, August 15, 2012 Invited Speaker. My most interesting, instructive, imposing or impressive case. Presentation 1 ANZET 2012. Brisbane, Australia, August 15, 2012 Invited Speaker. Percutaneous mitral valve repair: Climbing Everest with mitraclip. ANZET 2012. Brisbane, Australia, August 16, 2012 Invited Speaker. : LAA occlusion: Is it ready for prime time?. ANZET 2012. Brisbane, Australia, August 16, 2012 Invited Faculty:Panelist..for Live case for North Shore Hospital, Sydney. ANZET 2012. Brisbane, Australia, August 15, 2012 Invited Faculty. Panelist. Live Case the National Taiwan University Hospital, Taipei. ANZET 2012, Brisbane, Australia, August 15, 2012 Invited Faculty. Panelist. Live Case from the Prince Charles Hospital, Brisbane. ANZET 2012, Brisbane, Australia, August 15, 2012 Invited Faculty. Chairperson: The Current state of percutaneous valve interventions. CZANZ 2012 Annual Scientific Meeting, Brisbane, Australia. August 17, 2012 Invited Speaker. Mitral clip - A new therapy but who will benefit?. CZANZ Annual Scientific Meeting. Brisbane, Australia. August 18, 2012. Invited Speaker. MitraClip: Where does it Fit in the Mitral Paradigm of Care Saibal Kar .2012 AATS Mitral Valve Onclave. Nagano, Japan, September 17, 2012 Invited Faculty: Panelist, Live coronary session. Endovascular & Coronary Revascularisation in Seoul (ENCORE Seoul 20120, Seoul, Korea, September 20, 2012 Invited Speaker. Devices and Results; Watchman versus Amplatzer Cardiac Plug. Endovascular & Coronary Revascularisation in Seoul (ENCORE Seoul 20120, Seoul, Korea, September 20, 2012 Invited Speaker: Percutaneous mitral valve repair is a viable option for patients who are at high risk for surgery.. Endovascular & Coronary Revascularisation in Seoul (ENCORE Seoul 20120, Seoul, Korea, September 20, 2012 Page 34 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Speaker. Does closure of patent foramen ovale prevent recurrent strokes.. Endovascular & Coronary Revascularisation in Seoul (ENCORE Seoul 20120, Seoul, Korea, September 20, 2012 Invited Speaker. 10 important points for Watchman implantation. Endovascular & Coronary Revascularisation in Seoul (ENCORE Seoul 20120, Seoul, Korea, September 20, 2012 Invited Faculty: Moderator of the session meet the experts on the Watchman device. Endovascular & Coronary Revascularisation in Seoul (ENCORE Seoul 2012, Seoul, Korea, September 20, 2012 Invited Speaker. LAA occlusion; indications and clinical data. Endovascular & Coronary Revascularisation in Seoul (ENCORE Seoul 20120, Seoul, Korea, September 21, 2012 Invited Faculty: Live case operator (LAA closure) from Severance Hospital. Endovascular & Coronary Revascularisation in Seoul (ENCORE Seoul 20120, Seoul, Korea, September 21, 2012. Invited Speaker: Mitral Regurgitation: Percutaneous versus Surgical Repair. 23rd Great Wall International Congress of Cardiology Asia Pacific Heart Federation Scientific Congress. Beijing, China, October 13, 2012 Invited Faculty. Live case operator for a Watchman Case.3rd Asia Pacific Congenital & Structural Heart Intervention Symposium 2012, Hongkong. October 19, 2012 Invited Speaker. Complications and Tips & Tricks of MitralClip/ Leading Devices for Treating Mitral Valve Regurgitation. 3rd Asia Pacific Congenital & Structural Heart Intervention Symposium 2012, Hongkong. October 20, 2012 Invited Speaker. Why You Need a Multidisciplinary Heart Team: Case Scenario 2: Transcatheter Mitral Valve Repair. Annual meeting of Transcatheter Therapeutics (TCT 2012). October 22, 2012 Invited Speaker. Prevail Study Design and Current Status. Transcatheter Therapeutics(TCT 2012), October 23, 2012 Invited Speaker. WaveCrest (Coherex Medical): Device iteration, Human Outcomes, and Clinical Trial Directions. Transcatheter Therapeutics (TCT 2012). Miami, October 23, 2012 Invited Speaker. Optimal Transseptal Puncture for the MitraClip. Transcatheter Therapeutics (TCT 2012). Miami, October 24, 2012 Invited Faculty. Panelist. Live case presentation. Transcatheter Therapeutics (TCT 2012), October 25, 2012 Invited Speaker. The Expert MitraClip Procedure: From Transseptal Puncture to Echocardiographic Guidance and Procedural Tips and Tricks. Transcatheter Therapeutics(TCT 2012), Miami, October 26, 2012. Invited Speaker. Mitral valve repair, transcatheter approaches. Scientific sesson of the American Heart Association. Los Angeles, CA, USA, November 5, 2012 Invited Faculty. Moderator for the session: case selection of TAVR. Annual scientific session of the American Heart Association, Los Angeles, CA, USA, November 5, 2012 Invited Speaker. Transcatheter Mitral Valve Therapy. Annual scientific session of the American Heart Association, Los Angeles, CA, USA, November 7, 2012 Invited Speaker. LAA Closure Without Anticoagulation: ASAP Results and Clinical Experience. LAA focus workshop, Frankfurt, November 17, 2012 Invited Faculty. Chairperson of the session:Building a Program, Device Selection, Medical Management and Special Considerations. LAA focus workshop, Frankfurt, November 17, 2012 Page 35 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Faculty. Chairperson of the session: The Evidence for LAA Closure and New Developments. LAA focus workshop, Frankfurt, November 17, 2012. Invited Speaker. Watchman: Long-Term Follow-up of PROTECT AF. LAA focus workshop, Frankfurt, November 17, 2012 Invited Speaker. Coherex WaveCrest: Current Status and Future Directions. LAA focus workshop, Frankfurt, November 17, 2012 Invited Speaker: Watchman Device: Mechanics, Technique & Follow up. Left Atrial Appendage Hands on Animal Workshop 2012. Cardiovascular Preclinical Research Lab. Pyeongtaek, Korea, November 23, 2012 Invited Faculty: Hands on training using the Watchman Device. Left Atrial Appendage Hands on Animal Workshop 2012. Cardiovascular Preclinical Research Lab. Pyeongtaek, Korea, November 23, 2012. Invited Speaker. Endovascular approaches to LAA-Amplatzer Cardiac Plug II. Dallas-Leipzig Valve 2012 meeting, Dallas, December 5, 2012 Invited Faculty: Moderator: Session;State of The Art Imaging of Mitral Valve Disease. Dallas-Leipzig Valve 2012 meeting.Dallas, December 5, 2012 Invited Faculty: Moderator: Session; : Stroke Prevention: Drugs and Devices. Dallas-Leipzig Valve 2012 meeting. December 5, 2012 Invited Faculty. Moderator: Abstract session. Dallas-Leipzig Valve 2012, Dallas, December 6, 2012. Invited Speaker. Challenging case. Dallas-Leipzig Valve 2012, Dallas, December 5, 2012. Invited Speaker. The COAPT trial of the MitraClip Device. Dallas-Leipzig Valve 2012, Dallas, December 6, 2012. Invited Speaker. Percutaneous Cardiac Procedures: Current and Future Possibilites. 10 th Annual Emergency Medical Symposium. Los Angeles. December 7, 2012. Invited Speaker. Medicor Cardiovascular symposium, Izola, Slovenia, December 15, 2012 Invited Speaker. Percutaneous Mitral Valve Repair and Replacement. CIMS-CON 2013. January 4, 2013, Ahmedabad, INDIA Invited Speaker. Coronary angiography is still the gold standard. CIMS-CON 2013. January 4, 2013, Ahmedabad, INDIA Invited Faculty. Panelist: Truth about TAVI/TAVR, What all physicians need to know. CIMS-CON 2013. January 4, 2013, Ahmedabad, INDIA Invited Speaker. Cardioembolic stroke: What all physicians need to know. CIMS-CON 2013. January 5, 2013, Ahmedabad, INDIA Invited Speaker. Cardioembolic stroke. What all family physicians need to know. CIMS-CON 2013. January 6, 2013, Ahmedabad, INDIA Invited Speaker. WATCHMAN – Where do we stand? PICS-AICS 2013( Pediatric and Adult Cardiovascular Interventional Program). Miami, USA.January 20, 2013 Invited Speaker. LAA closure devices in development. PICS-AICS 2013( Pediatric and Adult Cardiovascular Interventional Program). Miami, Florida, USA. January 20, 2013 Invited Faculty. Live Case Operator from Cedars Sinai Medical Center transmitting to PICS-AICS 2013.( Pediatric and Adult Cardiovascular Interventional Program). Miami, USA.January 20, 2013 Page 36 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited Faculty. Live case operator from National Heart Center transmitted to AsiaPCR/SingLive 2013, Singapore, January 24, 2013 Invited Speaker: Transesophageal echocardiogram guided transseptal puncture for device implantation(including MitraClip and LAA occlusion devices) AsiaPCR/SingLIVE 2013, Singapore, January 25, 2013 Invited Faculty:Panelist for session: Transseptal with imaging guidance. AsiaPCR/SingLIVE 2013, Singapore, January 25, 2013 Invited speaker. Mitral valve repair and implantation in the cath lab; An overview of techniques and devices. 6th World Congress of Paediatric Cardiology and Cardiac Surgery. Cape Town, South Africa. February 19, 2013. Invited faculty: Moderator of session: Catheter interventions from fetus to adults. 6th World Congress of Paediatric Cardiology and Cardiac Surgery. Cape Town, South Africa. February 21, 2013 l Invited speaker. Results of percutaneous repair of the mitral valve. 6th World Congress of Paediatric Cardiology and Cardiac Surgery. Cape Town, South Africa. February 21, 2013 Invited speaker. MitraClip 2013. Asian Pacific Society of Cardiology 2013 Congress. Pataya, Thailand. February 23, 2013. Invited speaker. Tips for a Successful Mitral Clip Procedure. CRT 2013Washington DC. February 24, 2013. Invited faculty: Panelist. Valve and structural heart disease revolution for surgeons I. CRt 2013. Washington DC. February 24, 2013. Invited speaker. Percutaneous Approach to Mitral Valve Repair: Edge-to-Edge Mitral Leaflet Repair with the MitraClip--Technique Overview and a Taped Case. CRT 2013. Washington DC, February 24, 2013 Invited faculty. Panelist. Is Percutaneous Valve Repair Ready for Prime Time? For Whom?. CRT 2013, Washington DC. February 24, 2013. Invited speaker. Percutaneous mitral valve repair - Patient and device selection, Chennai, INDIA LIVE 2013. March 1, 2013 Invited speaker. Mitral valve repair: overview and take home message. Chennai, INDIA LIVE 2013, March 1, 2013 Invited speaker: Tips and tricks to prevention complications during LAA closure. 1 st International Symposium on Left Atrial Appendage, Kansas City, USA. March 2, 2013 Invited speaker:.ACP LAA Plug study. 1st International Symposium on Left Atrial Appendage. Kansas City, USA. March 2, 2013 Invited Faculty. Chairperson. Imaging Transcatheter Mitral Valve Procedures: MitraClip and Beyond. ACC i2 symposium, San Francisco, March 9, 2013 Invited Faculty. Chairperson. Understanding Mitral Valve Disease for the Interventionalist. TCT @ American College of Cardiology Scientific Meeting 2013, San Francisco, March 9, 2013 Invited speaker. Debate. All Moderate or Greater Residual Shunts after Device Closure Should be Closed. American College of Cardiology Scientific Meeting 2013, San Francisco, March 11, 2013 Invited speaker. Imaging for MitraClip Procedure. The 77th Annual Scientific Meeting of the Japanese Circulation Society(JCS 2013). Yokohama, Japan. March 16, 2013 Page 37 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited faculty. Moderator of session of transcatheter mitral valve therapies. China Interventional Therapeutics in partnership with TCT (CIT 2013), Beijing, China, March 22, 2013 Invited Speaker. Introduction to the MitraClip: Technical and Procedural Considerations, Case Selection and Early Clinical Outcomes. China Interventional Therapeutics in partnership with TCT (CIT 2013), Beijing, China, March 22, 2013 Invited speaker. Taped case on MitraClip. China Interventional Therapeutics in partnership with TCT (CIT 2013), Beijing, China, March 22, 2013 Invited faculty. Discussant, Live case session. China Interventional Therapeutics in partnership with TCT (CIT 2013), Beijing, China, March 22, 2013 Invited speaker. EVEREST II to Real World. Structural heart disease technology forum. Perth, Australia. March 27, 2013 Invited speaker. Watchman will Prevail. Structural heart disease technology forum. Perth, Australia. March 27, 2013 Invited speaker. EVEREST II to Real World. Structural heart disease technology forum. Fenix restaurant, Melbourne. Australia, March 27, 2013 Invited speaker. Watchman will Prevail. Structural heart disease technology forum. Fenix restaurant, Melbourne. Australia. March 27, 2013 Invited speaker. Percutaneous mitral valve repair: emerging options. Southwest Valve Summit, Austin, Texas, April 13, 2013. Invited speaker. Case: Mulivalve dysfunction. Southwest Valve Summit, Austin, Texas, April 13, 2013. Invited faculty. Moderator.MR treatment strategy. Southwest Valve Summit, Austin, Texas, April 13, 2013 Invited speaker.Transcaether LAA Occlusion: Morethan Anticoagulation-Title: Time to Intervene Transcatheter Therapeutics Asia Pacfic (TCT-AP2013), Seoul, Korea, April 24, 2013 Invited faculty. Panelist: Breakfast Meeting-Stroke Prevention Therapies: PFO, LAA, Transcatheter Therapeutics Asia Pacfic (TCT-AP2013). Seou, Korea, April 24, 2013 Invited faculty: discussant: Structural Heart Disease: Controversy 1: PFO CLosure for Stroke Prevention. Transcatheter Therapeutics Asia Pacfic (TCT-AP2013), Seoul, Korea, April 24, 2013. Invited faculty. Discussant. –Controversy#22 TAVR in Severe Aortic Stenosis.Transcatheter Therapeutics Asia Pacfic (TCT-AP2013). Seoul, Korea, April 24, 2013 Invited speaker. Watchman Luncheon Symposium-Latest Updated on LAAC and Its Clinical Evidence. Transcatheter Therapeutics Asia Pacfic (TCT-AP2013). Seoul, Korea. April 24, 2013 Invited speaker. Watchman Luncheon Symposium-Latest Updated on LAAC and Its Clinical Evidence. Transcatheter Therapeutics Asia Pacfic (TCT-AP2013). Seoul, Korea. April 24, 2013 Latest Update on LAAC and Its Clinical Evidence Invited speaker. Latest Update on LAAC and Its Clinical Evidence. Transcatheter Therapeutics Asia Pacfic (TCT-AP2013). Seoul, Korea. April 24, 2013 Invited speaker. Case Presentation: Best and Worst Cases of LAA Closure.Transcatheter Therapeutics Asia Pacfic (TCT-AP2013). Seoul, Korea. April 25, 2013 Invited faculty. Live case operator. Left atrial appendage occlusion case. Transcatheter Therapeutics Asia Page 38 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Pacfic (TCT-AP2013). Seoul, Korea. April 25[, 2013 Invited speaker. The Most Exciting New Technologies (Excluding Valves) in the Cath Lab and Their Impact on the Future. TCT@AATS2013, Minneapolis, May 8, 2013 Invited speaker. MitraClip: Why Isn't it Taking Off?. TCT@AATS2013, Minneapolis, May 8, 2013 Invited speaker. Debate on clip versus surgery in FMR-Pro(debate0. Society for Cardiovascular Angiography and Interventions 2013 scientific session. Orlando, Florida, US. May 9, 2013. Invited speaker. Challenging Case Example LAA Occlusion –Watchman. Society for Cardiovascular Angiography and Interventions 2013 scientific session. Orlando, Florida, US. May 10, 2013. Invited faculty. Discussant. Indications, contradictions and complications for PFO, ASD, LAA Closure Society for Cardiovascular Angiography and Interventions 2013 scientific session. Orlando, Florida May 10, 2013 Invited speaker. A Septal Occluder with Fully Biodegradable Frame. Society for Cardiovascular Angiography and Interventions 2013 scientific session. Orlando, Florida May 10, 2013 Invited speaker. Medicine grand rounds. Pills, patches, and umbrellas for the prevention of cardioembolic stroke. Cedars Sinai Medical center. May 17, 2013 Invited faculty. Transcatheter Valve therapeutics 2013. Live case operator for a MitraClip procedure at St Paul’s Hospital, Vancouver, Canada. Invited speaker. World experience using the MitraClip. Cardiac Sciences Clinical Institute Symposium. Melbourne, Australia, October 19, 2013 Invited speaker: Latest insights on the clinical evidences: from PROTECT AF to PREVAIL. UK Heart Rhythm Conference , Birmingham UK, October 21, 2013 Invited speaker. Biological response following Watchman and Amplatzer Cardiac Plug implant. UK Heart Rhythm Conference , Birmingham UK, October 21, 2013 Invited speaker. Deep dive of the Watchman Data. Protect AF, CAP AND PREVAIL, Safety Issues.Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 27, 2013 Invited faculty. Discussant. Session; Session: The Evidence for LAA Closure: Current and Emerging Indications. Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 27, 2013 Invited faculty. Moderator. Session; The Technique of LAA Closure. Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 27, 2013 Invited speaker. Watchman Device. Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 27, 2013 Invited speaker. Data Presented to the FDA to Support a Degenerative MR Indication in Patients Too High Risk for Surgery.Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 28, 2013 Invited faculty. Discussant: The MitraClip in Degenerative MR. Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 28, 2013 Invited faculty. Moderator. Session; The MitraClip in Functional MR. Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 28, 2013 nvited speaker. Debate; If I Had to Have Just One for Functional MR..Give me the MitraClip. Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 28, 2013 Page 39 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited faculty. Next generation Mitral Valve Therapies Part 1: Today’s Contenders. Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 28, 2013 Invited speaker. Are Novel LAA Closure Devices ( Beyond Watchman) needed in the USA.Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 28, 2013 Invited faculty. Discussant . Partnership Sesson: The Interventional Gap Between Europe and the United States: Devices available in Germany but Not the United States, Session III LAA Closure Devices. Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 28, 2013 Invited faculty.MODERATOR-PHARMACOLOGICAL & INTERVENTIONAL OPTIONS FOR STROKE PREVENTION IN ATRIAL FIB-Session V. Provocative Cases: the Good, the Bad and the Ugly Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 29, 2013 Invited speaker. Left Atrial Appendage Occlusion: A Valid Option to Anticoagulation for Long-term Prevention of Stroke. Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 29, 2013 Invited faculty:Discussant. Stroke in Atrial fibrillation: A Preventable Condition. Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 29, 2013 Invited speaker. The MitraClip for functional MR.Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 29, 2013 Invited faculty. Interventional, Surgical and Hybrid Procedures: Case Studies in Conflict and Consensus( Co-sponsored by the American Association for Thoracic Surgery) Session IV. Mitral Valve Disease..Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 29, 2013 Invited faculty. Chairperson. Mitralign: Applications for Mitral and Tricuspid Diseases. .Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 30, 2013 Invited faculty. Live case operator: Left main stenting. .Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 30, 2013 Invited speaker. Transseptal puncture for functional MR, case presentation. .Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 30, 2013 Invited speaker. Transseptal puncture for Mobile Interatrial Septum Therapeutics(TCT 2013). San Francisco, US. October 30, 2013 Invited speaker. The MitraClip Procedure: Getting in and out of trouble..Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 30, 2013 Invited faculty. The MitraClip Porcedure Broken Down..Transcatheter Therapeutics(TCT 2013). San Francisco, US. October 30, 2013 Invited faculty. Plenary Session XXVIII. Clinically Oriented Case-Based Tutorials II. Aortic and Mitral Valve Disease. Transcatheter Therapeutics(TCT 2013). San Francisco, US. November 1k, 2013 Invited speaker. Current status of mitral valve interventions. 9th Asian Cardiovascular Therapeutics, Bangkok, Thailand, November 14, 2013 Invited faculty. Live case demonstration of Left atrial appendage occlude. 9 th Asian Cardiovascular Therapeutics, Bangkok, Thailand, November 15, 2013 Invited speaker. Patent Foramen Ovale and Stroke: To Close or Not to Close . 9th Asian Cardiovascular Therapeutics, Bangkok, Thailand, November 15, 2013 Page 40 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Invited speaker. Advanced Support Systems during High Risk PCI . 9th Asian Cardiovascular Therapeutics, Bangkok, Thailand, November 15, 2013 Invited speaker. Percutaneous Mitral Valve Repair an indication update. The 4 th Sendai/New Tokyo Live. Sendai, Japan, November 30, 2013 Invited faculty. Panelist for Live ASD closure case. The 4th Sendai/New Tokyo Live. Sendai, Japan, November 30, 2013 Invited Speaker. Structural Heart Disease Program in Medicor, Izola.Medicor Cardiovascular symposium, Izola, Slovenia, December 14, 2012 Invited speaker. “MitraClip” Current status in United States. The 20th Kamakura Live Demonstration Course. Yokohama, Kanagawa, Japan, December 20, 2013 Invited speaker. “Percutaneous Mitral Valve Repair: Adding Life to Years”. The Abbott Vascular Symposium at the 20th Kamakura Live Demonstration Course, Yokohama, Kanagawa, Japan, December 21, 2013 Invited faculty. Live case commentator. The 20th Kamakura Live Demonstration Course, Yokohama, Kanagawa, Japan. December 21, 2013. Invited speaker. Status of closure of Patent Foramen Ovale and Left atrial closure for the prevention of stroke. 6th annual symposium on Neurovascular disease 2014, Los Angeles, CA, USA, January 25, 2014. Invited speaker. Percutaneous Mitral Valve Interventions; Edge to Edge repair to replacement. Innovative Procedures, Devices,and State of the Art Care for Arrhythmias, Heart Failure and Structural Heart Disease. Hilton Hawaiian Village, Honolulu, Hawaii, USA. February 1, 2014 Invited faculty. Discussant on Left atrial appendage closure. jInnovative Procedures, Devices,and State of the Art Care for Arrhythmias, Heart Failure and Structural Heart Disease. Hilton Hawaiian Village, Honolulu, Hawaii, USA. February 1, 2014 Invited speaker. Newer devices on Mitraclip. Abbott Training symposium. Los Angeles, CA, USA. February 7, 2014 VISITING PROFESSORSHIP Visiting Professor MC Medcor, Izola, Slovenia, September 2007 Scripps Green Hospital, San Diego, CA. Complex structural heart disease interventions UCI Medical Center, Irvine, CA. Help in performance of complex structural heart disease interventions Visiting Faculty: Cath Lab. University of Hamburg, Eppendorf, Hamburg, Germany, August 5, 2009 PUBLICATIONS/BIBLIOGRAPHY A. Research Papers - Peer reviewed Maity AK, Chatterjee SS, Todi S, Kar S, Chakinpurty M, Ganguly K, Kar CC: Profile of Renal Artery Stenosis with Reference to Aortoarteritis. Ind Heart J 1986 Nov; 38(6): 451-6 Ghosh Sukumar, Choudhury D, Chatterjee SS,Kar S,Maity AK, Kar CC: Role of Echocardiography in Borderline Hypertension. Ind Heart J 1988 Nov: 40(6): 460-5 Sagar S, Kar S, Gupta A, Sharma BK: Ocular Changes in Takayasu's Arteritis in India. Jpn J Ophthalmol 1994; 38: 97-102 Sloman JG, Kar S: Cardiovascular Problems: Three cases requiring angioplasty. Current Therapeutics Page 41 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 1996; Feb: 31 – 34 Saibal Kar, Raj Makkar: Case review: Percutaneous Transluminal Septal Myocardial Ablation: A Novel, Nonsurgical Treatment for Hypertrophic Cardiomyopathy. Rev Cardiovasc Med 2001;2:97-102 6. Saibal Kar, Prediman K Shah: Acute Coronary Dissection Caused by Coronary Artery Dissection Mimicking Acute Plaque Rupture. Rev Cardiovasc Med 2001; 2(4):215-219 7. Matetzky S, Noc M, Domingo M, Eigler N, Kar S, Shah PK, Cercek B. Primary angioplasty in octogenarians. Am J Cardiol 2001; 88: 680-684 8. Noc M. Matetzky S. Domingo M. Kar S. Makkar R. Cercek B. Litvack F. Frequency of incomplete reperfusion in patients with acute myocardial infarction undergoing primary angioplasty. Am J of Cardiol 2002; 90(3):316-8 9. Ariel Finkelstein MD; Dougal McClean MB ChB MD; Saibal Kar MD; Kaname Takizawa MD; Kiron Vargeese MD; Kinam Park PhD; Michael C. Fishbein MD; Raj Makkar MD; Frank Litvack MD; Neal L. Eigler MD.Local Drug Delivery via a Coronary Stent With Programmable Release Pharmacokinetics. Circulation 2003;107: 777-784 10. Matetzky S. Domingo M. Kar S. Noc M. Shah PK. Kaul S. Daar E. Cercek B. Acute myocardial infarction in human immunodeficiency virus-infected patients. Archives of Internal Medicine. 2003;163(4):457-60 11. Rukshin V. Santos R. Gheorghiu M. Shah PK. Kar S. Padmanabhan S. Azarbal B. Tsang VT. Makkar R. Samuels B. Lepor N. Geft I. Tabak S. Khorsandhi M. Buchbinder N. Eigler N. Cercek B. Hodgson K. Kaul S. A prospective, nonrandomized, open-labeled pilot study investigating the use of magnesium in patients undergoing nonacute Percutaneous coronary intervention with stent implantation. Journal of Cardiovascular Pharmacology & Therapeutics 2003; 8(3):193-200 12. Eberhard Grube; Shinjo Sonoda; Fumiaki Ikeno; Yasuhiro Honda; Saibal Kar; Charles Chan; Ulrich Gerckens; Alexander J. Lansky; Peter Fitzgerald. Six- and Twelve-Month Results From First Human Experience Everolimus-Eluting Stents With Bioabsorbable Polymer. Circulation 2004;109:2168-2171 13. Shengmei Zhou, MD, Lan S. Chen, MD, Yasushi Miyauchi, MD, Mizuho Miyauchi, MD, Saibal Kar, MD, Simon Kangavari, MD, Michael C. Fishbein, MD, Behrooz Sharifi, PhD, Peng-Sheng Chen, MD. Mechanisms of Cardiac Nerve Sprouting After Myocardial Infarction in Dogs. Short title: Mechanisms of Cardiac Nerve Sprouting. Circulation Research 2004;95:76-83 14. Fatma Aboul-Enein, MD; Saibal Kar, MD; Sean W. Hayes, MD; Maria Sciammarella, MD; Aiden Abidov, MD; Raj Makkar, MD; John D Friedman, MD; Neal Eigler, MD; Daniel S Berman, MD. Influence of Angiographic collateral Circulation on Myocardial Perfusion in Patients with Chronic Total Occlusion of a Single Coronary Artery and No Prior Myocardial Infarction. J Nucl Med 2004;45:950-955 15. Okuyama Y, Pak H-N, Miyauchi Y, Liu Y-B, Chou C-C, Hayashi H, Fu KJ, Kerwin WF, Kar S, Karagueuzian HS, Fishbein MC, Chen P-S, Chen LS: Sympathetic nerve sprouting induced by radiofrequency catheter ablation in dogs. Heart Rhythm 2004;1:712-7 16. Aragon J, Lee MS, Kar S, Makkar RR. Percutaneous left ventricular assist device: “TandemHeart” for high-risk coronary intervention. Catheter Cardiovasc Interv 2005;65:346-52 Page 42 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 17. Lee MS, Shah AP, Jamali A, Kar S, Dohad S, Aragon J, Makkar RR. Drug-eluting stenting is superior to bare-metal stenting in saphenous vein grafts. Catheter Cardiovasc Interv 2005 Dec;66(4):507-11 18. Kobal SL, Trento L, Baharami S, Tolstrup K, Naqvi TZ, Cercek B, Neuman Y, Mirocha J, Kar S, Forrester JS, Siegel RJ. Comparison of effectiveness of hand-carried ultrasound to bedside cardiovascular physical examination. Am J Cardiol, 2005 Oct 1;96(7):1002-6 19. Matthew J Price, Chung-Chuan Chou, Malka Frantzen, Takashi Miyamoto, Saibal Kar, Steve Lee, Prediman K Shah, Bradley J Martin, Michael Lill, James S Forrester, Peng-Sheng Chen, Raj Makkar. Intravenous mesenchymal stem cell therapy early after reperfused acute myocardial infarction improves left ventricular function and alters electrophysiological properties. Int J Cardiol. 2005: Oct 21 20. Michael S Lee, Nikil Kapoor, Faizi Jamal, Lawrence Czer, Joseph Aragon, James Forrester, Saibal Kar, Sohail Dohad, Robert Kass, Neal Eigler, Alfredo Trento, Prediman K Shah, Raj Makkar. Comparison of coronary artery bypass surgery with percutaneous coronary intervention with drug eluting stents for unprotected left main coronary artery disease. J Am Coll Cardiol. 2006 Feb 21;47(4):864-70 21. Makkar RR, Price MJ, Lill M, Frantzen M, Takizawa K, Kleisli T, Zheng J, Kar S, McClelan R, Miyamota T, Bick-Forrester J, Fishbein MC, Shah PK, Forrester JS, Sharifi B, Chen PS, Qayyum M. Intramyocardial injection of allogenic bone marrow-Derived mesenchymal stem cells without immunosuppression preserves cardiac function in a porcine model of myocardial infarction. J Cardiovasc Pharmacol Ther. 2005 ;10(4):225-33 22. J Aragon, S. Kar, F.Tio, B. Trauthen, A. Parisky, C. Watanabe, A. Jamali, N. Eigler, P.W.Serruys, F. Litvack. The effect of variable release kinetics on Paclitaxel efficacy rom a drug eluting stent in a porcine model . EuroIntervention, Issue 2, 2005 23. Ritzema-Carter JL, Smyth D, Troughton RW, Crozier IG, Melton IC, Richards AM, Eigler N, Whiting J, Kar S, Krum H, Abraham WTImages in cardiovascular medicine. Dynamic myocardial ischemia caused by circumflex artery stenosis detected by a new Implantable Left Atrial Pressure Monitoring Device. Circulation. 2006 Apr 18;113(15):e705-6 24. Kangavari S, Yong Seog OH, Shengmei Z, Ho-Joong Y, Man-Young L, Wook-Sung J, Tae-ho R, Soon-Jo H, Kar S, Kerwin WF, Swerdlow CD, Gang ES, Gallik DM, Goodman JS, Chen YI, Chen PS. Radiofrequency Catheter Ablation and Nerve Growth Factor Concentration in Humans. Heart Rhythm. 2006 Oct;3(10):1150-5. Epub 2006 Jul 8 25. McClean D, Jamali A, Aragon J, Kar S, Whiting J, Ritzema-Carter J, Troughton R, Krum H, Doughty R, Abraham W, Eigler N. Non-invasive calibration of cardiac pressure transducers in patients with heart failure: An Aid to implantable hemodynamic monitoring and therapeutic guidance. J Card Fail. 2006 Sep;12(7):568-76 26. Michael S Lee, Daniel Jurewitz, Joseph Aragon, James Forrester, Raj Makkar, Page 43 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Saibal Kar. Stent Fracture Associated with Drug-Eluting Stents: Clinical Characteristics and Implications. Catheter Cardiovasc Interv. 2007 Feb 15;69(3):387-94 27. Jay Ritzema, Iain C Melton, Mark Richards, Ian G Crozier, Chris Frampton, Robert N Doughty, James Whiting, Saibal Kar, Neal Eigler, Hernry Krum, William Abraham, Richard Troughton. Direct Left Atrial Pressure Monitoring in Ambulatory Heart Failure Patients. Circulation 007;116:2952-2959 28. Ryan Berg, Joseph Aragon, Vladimir Royter, John F Shanley, Greg Cogert, Renu Vermani, Saibal Kar, Neal Eigler, Frank Litvack. Pimecrolimus and Dual Pimecrolimus-Paclitaxel Eluting Stents Decrease Neointimal Proliferation in a Porcine Model. Catheterization and Cardiovascular Interventions. 2007;70:871–879 29. L. Iri Kupferwasser, MD, FESc, Allen M. Amorn, MD, Nikhil Kapoor, MD, Michael S. Lee, MD, Saibal Kar, MD, FACC, Bojan Cercek, MD, FACC, Suhail Dohad, MD, James Mirocha, PhD, James S. Forrester, MD, FACC, Prediman K. Shah, MD, FACC, and Raj R. Makkar,* MD Comparison of Drug-Eluting Stents With Bare Metal Stents in Unselected Patients With Acute Myocardial Infarction. Catheterization and Cardiovascular Interventions 2007; 70:1-8 30. Ted Feldman, Saibal Kar. Percutaneous Mitral Valve Repair Technologies: Surgical Concepts Adapted to Catheter-based Approaches. Indian Heart J 2008; 60:507-513 . 31. Anthony J. White, MBBS, PHD,* Gautam Kedia, MD,* James M. Mirocha, MS,* Michael S. Lee, MD,† James S. Forrester, MD,* Walter C. Morales, BS,* Suhail Dohad, MD,* Saibal Kar, MD,* Lawrence S. Czer, MD,* Gregory P. Fontana, MD,* Alfredo Trento, MD,* Prediman K. Shah, MD,* Raj R. Makkar, MD* Comparison of Coronary Artery Bypass Surgery and Percutaneous Drug-Eluting Stent Implantation for Treatment of Left Mainoronary Artery Stenosis. J Am Coll Cardiol 2008;1:236-245. 31. Herrmann HC, Kar S, Siegel R, Fail P, Loghin C, Lim S, Hahn R, Rogers JH, Bommer WJ, Wang A, Berke A, Lerakis S, Kramer P, Wong SC, Foster E, Glower D, Feldman T; EVEREST Investigators. Effect of percutaneous mitral repair with the MitraClip device on mitral valve area and gradient.Eurointerventions 2009:4(4): 437-442. 32. Takashi Akima, MD, Rajendra Makkar, MD, Toshihiko Nishioka, MD, Suhail Dohad, MD, Kiyoshi Iida, MD, Sorel Goland, MD, Saibal Kar, MD, Huai Luo, MD, Robert J. Siegel, MD Impact of Nitroglycerin and Verapamil on Coronary Arterial Distensibility as Assessed by Intravascular Ultrasound. J Invasive Cardiol 2009;21:162–167 33. Ted Feldman, MD, Saibal Kar, MD, Michael Rinaldi, MD,Peter Fail, MD, James Hermiller, MD,_ Richard Smalling, MD, PHD, Patrick L. Whitlow, MD,William Gray, MD, Reginald Low, MD, Howard C. Herrmann, MD, Scott Lim, MD, Elyse Foster, MD,Donald Glower, MD, for the EVEREST Investigators. Percutaneous Mitral Repair With the MitraClip System Safety and Midterm Durability in the Initial EVEREST (Endovascular Valve Edge-to-Edge REpair Study) Cohort J. Am. Coll. Cardiol. 2009;54;686-694 34. Wertman BM, Cheng VY, Kar S, Gransar H, Berg RA, Naik H, Makkar R, Friedman JD, Schapira JN, Berman DS. Characterization of complex coronary artery stenosis morphology by coronary computed tomography angiography. JACC Cardiovasc Imaging 2009;8:950-958 Page 44 of 65 Curriculum Vitae 35. Saibal Kar, M.D, FAHA, FACC, FSCAI Melmed G, Kar S, Geft I, Lo S. A new method for endoscopic closure of gastrocolonic fistula: novel application of a cardiac septal defect closure device(video). Gastrointestinal Endoscopy 2009; 70: 542-545. 36 Asma Hussaini, Saibal Kar. Percutaneous Mitral Valve Repair: Potential in Heart Failure Management. Curr Heart Fail Rep 2010;7:22-26. 37. Norio Tada,; Renu Virmani, ; Gordon Grant, Lauren Bartlett, Alexander Black,; Claudia Clavijo,; Uwe Christians, Ron Betts, Doug Savage, John Shulze ,Saibal Kar. Polymer-Free Biolimus A9 Eluting Stent Demonstrates More Sustained Intimal Inhibition, Improved Healing and Reduced Inflammation in Comparison to a Polymer-Coated Sirolimus Eluting Cypher Stent in a Porcine Model. Circ Cardiovasc Interv. 2010;3:174-183. 38. Ritzema J, Troughton R, Melton I, Crozier I, Doughty R, Krum H, Walton A, Adamson P, Kar S, Shah PK, Richards M, Eigler NL, Whiting JS, Haas GJ, Heywood JT, Frampton CM, Abraham WT; Hemodynamically Guided Home Self-Therapy in Severe Heart Failure Patients (HOMEOSTASIS) Study Group. Physician-directed patient self-management of left atrial pressure in advanced chronic heart failure. Circulation. 2010 ;121(9):1086-95. 39. Biner S, Kar S, Siegel RJ, Rafique A, Shiota T. Value of color Doppler three-dimensional transesophageal echocardiography in the percutaneous closure of mitral prosthesis paravalvular leak. Am J Cardiol 2010;105(7): 984-989. 40. Anthony J. Furlan MD*; Mark Reisman MD; Joseph Massaro PhD; Laura Mauri MD, MSc; Harold Adams MD; Gregory W. Albers MD; Robert Felberg MD; Howard Herrmann MD; Saibal Kar MD; Michael Landzberg MD; Albert Raizner MD; Lawrence Wechsler MD; for the CLOSURE I Investigators. Study Design of the CLOSURE I Trial. A Prospective, Multicenter, Randomized, Controlled Trial to Evaluate the Safety and Efficacy of the STARFlex Septal Closure System Versus Best Medical Therapy in Patients With Stroke or Transient Ischemic Attack Due to Presumed Paradoxical Embolism Through a Patent Foramen Ovale. Stroke 2010; 41(12):2872-2883. 41. Siegel RJ, Biner S, Rafique AM, Rinaldi M, Lim S, Fail P, Hermiller J, Smalling R, Whitlow PL, Herrmann HC, Foster E, Feldman T, Glower D, Kar S; EVEREST Investigators. The acute hemodynamic effects of MitraClip therapy. J Am Coll Cardiol 2011;57;1658-1665. 42. Mehran Khorsandi, MD; Alex Abizaid,MD; Sameer Dani, MD; Henry Bourang, MD; Ricardo Costa, MD; Saibal Kar, MD; Raj Makkar, MD. Advanced Bifurcation Systems’ mother daughter platform. Eurointerventions, 2010;6(Suppl J):J165-J168 43. Vivek Y. Reddy, David Holmes, Shepahl K. Doshi, Petr Neuzil, and Saibal Kar. Safety of Percutaneous Left Atrial Appendage Closure: Results from the Watchman Left Atrial Appendage System for Embolic Protection in Patients with AF (PROTECT AF) Clinical Trial and the Continued Access Registry. Circulation, 2011;123:417-424. Page 45 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 44. Ted Feldman, M.D., Elyse Foster, M.D., Donald G. Glower, M.D., Saibal Kar, M.D., Michael J. Rinaldi, M.D., Peter S. Fail, M.D., Richard W. Smalling, M.D., Ph.D., Robert Siegel, M.D., Geoffrey A. Rose, M.D.,Eric Engeron, M.D., Catalin Loghin, M.D., Alfredo Trento, M.D., Eric R. Skipper, M.D., Tommy Fudge, M.D.,George V. Letsou, M.D., Joseph M. Massaro, Ph.D., and Laura Mauri, M.D., for the EVEREST II Investigators. Percutaneous Repair or Surgery for Mitral Regurgitation. N Engl J Med 2011; 364 :1395-1406. 45. Hasan Jilaihawi, Saibal Kar. Left Atrial Appendage Occlusion:An Alternative to Long Term Coumadin forPatients with Atrial Fibrillation. Revista Brasiliera de Cardiologia Invasiva 2011;19(1): 9-10. 46. Damien Kenny , MD, Ziyad M. Hijazi 1, MD, MPH, Saibal Kar 2, MD, John Rhodes 3, MD, Michael Mullen 4, MD, Raj Makkar 2, MD, Girish Shirali 5, MD, Mark Fogel 6, MD, John Fahey 7, MD, Mary G Heitschmidt 1,RN, Christopher Cain. Percutaneous Implantation of the Edwards SAPIEN Transcatheter Heart Valve for Conduit Failure in the Pulmonary Position: Early Phase 1 Results from an International Mutlticenter Clinical Trial. J Am Coll of Cardiol 2011(in press) 47. Jilaihawi H, Kar S, Doctor N, Fontana G, Makkar R. Contemporary application of cardiovascular hemodynamics: transcatheter aortic valve interventions. Cardiol Clin.2011;29:211-222. 48. Jilaihawi H, Makkar R, Hussaini A, Trento A, Kar S. Contemporary application of cardiovascular hemodynamics:transcatheter mitral valve interventions. Cardiol Clin.2011;29:201-209. 49. Biner S, Perk G, Kar S, Rafique AM, Slater J, Shiota T, Hussaini A, Chou S, Kronzon I, Siegel RJ.Utility of combined two-dimensional and three dimensional transesophageal imaging for catheter-based mitral valve clip repair of mitral regurgitation. J Am Soc Echocardiogr. 2011 Jun;24:611-617. 50. Azarbal B, Poommipanit P, Arbit B, Hage A, Patel J, Kittleson M, Kar S, Kaldas FM, Busuttil RW. Feasibility and safety of percutaneous coronary intervention in patients with end-stage liver disease referred for liver transplantation. Liver Transpl.2011;17(7):809-813. 51. Buch MH, Trento A, Kar S Is there a role for surgeons in transcatheter mitral valve procedures? Curr Opin Cardiol. 2011;26(2):99-105. 52. Thompson KA, Kar S, Makkar R, Victor RG.Drug-resistant hypertension: is renal sympathetic denervation the answer? Curr Cardiol Rep. 2011;13(2):93-95. 53. Chakravarty T, White AJ, Buch M, Naik H, Doctor N, Schapira J, Kar S, Forrester JS, Weiss RE, Makkar R. Meta-analysis of incidence clinical characteristics and implications of stent fracture. Am J Cardiol;106(8):1075-1080. 54. Jilaihawi H, Hussaini A, Kar S. MitraClip: a novel percutaneous approach to mitral valve repair. J Zhejiang Univ Sci B. 2011 Aug.;12(8):633-637. 55. Perk G, Biner S, Kronzon I, Saric M, Chinitz L, Thompson K, Shiota T, Hussani A, Lang R, Siegel R, Kar S. Catheter-based left atrial appendage occlusion procedure: role of echocardiography.Eur J Echocardiogr. 2011 Sep 8. Kulkarni M, Conte AH, Huang A, Lubin L, Shiota T, Kar S. Coronary artery disease, acute myocardial infarction, and a newly developing ventricular septal defect: surgical repair or percutaneous closure? J Cardiothorac Vasc Anesth. 2011 Dec;25(6):1213-6. 56. Page 46 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 57. Nataša Černič Šuligoj, Metka Zorc, Anton Grad, Saibal Kar, Marko Noč. Percutaneous closure of patent foramen ovale – experience with novel devices. Slov Kardiol 2011; 8: 15–19 58. Whitow PL, Feldman T, Pedersen WR, Lim DS, Kipperman R, Smalling R, Bajwa T, Hermann HC, Lasala J, Maddux JT, Tuzcu M, Kapadia S, Trento A, Siegel, RJ, Foster E, Glower D, Mauri L, Kar S; EVEREST II Investigators. Acute and 12-month results with catheter-based mitral valve leaflet repair: The EVEREST II(Endovascular Valve Edge-to-Edge Repair) high-risk study. J Am Coll Cardiol 2012;59:130-139 58 Juan F. Viles-Gonzalez, , Saibal Kar, , Pamela Douglas, , Srinivas Dukkipati, , Ted Feldman, , Rodney Horton, ,David Holmes, , Vivek Y. Reddy, . The Clinical Impact of Incomplete Left Atrial Appendage Closure With the Watchman Device in Patients With Atrial Fibrillation A PROTECT AF (Percutaneous Closure of the Left Atrial Appendage Versus Warfarin Therapy for Prevention of Stroke in Patients With Atrial Fibrillation) Substudy J Am Coll Cardiol. 2012;59:923-929 59. Anthony J. Furlan, M.D., Mark Reisman, M.D., Joseph Massaro, Ph.D.,Laura Mauri, M.D., Harold Adams, M.D., Gregory W. Albers, M.D.,Robert Felberg, M.D., Howard Herrmann, M.D., Saibal Kar, M.D.,Michael Landzberg, M.D., Albert Raizner, M.D.,and Lawrence Wechsler, M.D., for the CLOSURE I Investigators. N Engl J Med;2012:991-9. 60. Saitoh T, Izumo M, Furugen A, Tanaka J, Miyata-Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Kar S, Shiota T. Echocardiographic evaluation of iatrogenic atrial septal defect after catheter-based mitral valve clip insertion. Am J Cardiol. 2012;109(12):1787-91 61. Kar S, Ibebuogu UN, Conte AH. Utilization of 3 amplatzer occluders for closure of post-myocardial infarction ventricular septal defect. J Invasive Cardiol. 2012 May;24(5):E101-3 62. Biner S, Siegel RJ, Feldman T, Rafique AM, Trento A, Whitlow P, Rogers J, Moon M, Lindman B, Zajarias A, Glower D, Kar S; EVEREST investigators. Acute effect of percutaneous MitraClip therapy in patients with haemodynamic decompensation. Eur J Heart Fail. 2012;14(8):939-45. 63. Wei J, Mehta PK, Johnson BD, Samuels B, Kar S, Anderson RD, Azarbal B, Petersen J, Sharaf B, Handberg E, Shufelt C, Kothawade K, Sopko G, Lerman A, Shaw L, Kelsey SF, Pepine CJ, Merz CN. Safety of coronary reactivity testing in women with no obstructive coronary artery disease: results from the NHLBI-sponsored WISE (Women's Ischemia Syndrome Evaluation) study. JACC Cardiovasc Interv. 2012;5(6):646-53 64. Ibebuogu UN, Cercek B, Makkar R, Dinh H, Kwarteng C, Mirocha J, Hussaini A, Singh S, Dohad S, Shah PK, Khorsandi M, Kar S. Comparison between transradial and transfemoral percutaneous coronary intervention in acute ST-elevation myocardial infarction. Am J Cardiol. 2012 Nov 1;110(9):1262-5. 65. Slipczuk L, Siegel RJ, Jilaihawi H, Hussaini A, Kar S. Optimizing procedural outcomes in percutaneous mitral valve therapy using transesophageal imaging: a stepwise analysis. Expert Rev Cardiovasc Ther. 2012 Jul;10(7):901-16. 66. Matsumoto T, Yeow WL, Kar S. Percutaneous closure of iatrogenic ventricular septal defect following surgical aortic valve replacement using two different approaches. J Invasive Cardiol. 2013 Feb;25(2):E42-4. Page 47 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 67. Izumo M, Shiota M, Kar S, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Comparison of real-time three-dimensional transesophageal echocardiography to two-dimensional transesophageal echocardiography for quantification of mitral valve prolapse in patients with severe mitral regurgitation. Am J Cardiol. 2013 Feb 15;111(4):588-94 68. Matsumoto T, Nakamura M, Yeow WL, Siegel RJ, Kar S. Transcatheter Left Atrial Appendage Closure After Incomplete Surgical Ligation. JACC Cardiovasc Interv. 2013 Feb;6(2):e11-2. 69. Chowdhury SM, Hijazi ZM, Rhodes J, Kar S, Makkar R, Mullen M, Cao QL, King L, Akin J, Shirali G. Early Echocardiographic Changes After Percutaneous Implantation of the Edwards SAPIEN Transcatheter Heart Valve in the Pulmonary Position. Echocardiography. 2013 Feb 22 70. Alli O, Doshi S, Kar S, Reddy V, Sievert H, Mullin C, Swarup V, Whisenant B, Holmes D Jr. Quality of Life Assessment in the Randomized PROTECT AF (Percutaneous Closure of the Left Atrial Appendage Versus Warfarin Therapy for Prevention of Stroke in Patients With Atrial Fibrillation) Trial of Patients at Risk for Stroke With Nonvalvular Atrial Fibrillation. J Am Coll Cardiol 2013 Apr 30;61(17):1790-8 71. Foster E, Kwan D, Feldman T, Weissman N, Grayburn P, Schwartz A, Rogers J, Kar S, Rinaldi M, Fail P, Hermiller J, Whitlow PL, Herrmann HC, Lim S, Glower D. Percutaneous Mitral Valve Repair in the Initial EVEREST Cohort: Evidence of Reverse Left Ventricular Remodeling. Circ Cardiovasc Imaging. 2013 Apr 30. 72. Yi GH, Cheng Y, Aboodi MS, Farnan R, Kar S, Burkhoff D, Farnan G, Granada JF. Safety and feasibility of percutaneous delivery of a novel circulatory assist device (CircuLite® SYNERGY®) in the swine model. EuroIntervention. 2013 Jun 22;9(2):259-68 73. Chakravarty T, Jilaihawi H, Nakamura M, Kashif M, Kar S, Cheng W, Makkar R. Pre-emptive positioning of a coronary stent in the left anterior descending artery for left main protection: A prerequisite for transcatheter aortic valve-in-valve implantation for failing stentless bioprostheses? Catheter Cardiovasc Interv. 2013 Jun 1. doi: 10.1002/ccd.25037. 74. Matsumoto T, Yeow WL, Nakamura M, Siegel RJ, Kar S. Reply. JACC Cardiovasc Interv. 2013 Jul;6(7):762-3 75. Kar, Saibal. Percutaneous transcatheter Mitral Valve Repair: Adding life to years. . J Am Coll Cardiol 2013; 62:1063-1064. 76. Lim DS, Reynolds MR, Feldman T, Kar S, Herrmann HC, Wang A, Whitlow PL, Gray WA, Grayburn P, Mack MJ, Glower D. Improved Functional Status and Quality of Life in Prohibitive Surgical Risk Patients With Degenerative Mitral Regurgitation Following Transcatheter Mitral Valve Repair with the MitraClip® System. J Am Coll Cardiol. 2013 Oct 24. doi:pii: S0735-1097 D. Research Papers(Non peer reviewed) 1. Kar S, Grover A, Varma JS, Khattri HN, Bidwai PS: Permanent Pacing in Children Asia Pace News 1995; 10: 92 2. Saibal Kar, Ted E. Feldman, Frederick St. Goar. Mitral Valve Repair Using the MitraClip: From Concept to Reality. Cardiac Interventions Today. May/June 2008 Page 48 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI CHAPTERS 1. Kar S, Litvack F: Excimer Laser Coronary Angioplasty in Practical Interventional Cardiology,2nd Ed (Eds. Ever Grech and David Ramsdale)(Martin Dunitz, 2000) 2. Saibal Kar, Prediman K Shah. Coronary Circulation. Colour Handbook of Ischemic Heart Disease. 1st Ed(Editors. Erling Falk, Prediman K Shah) (in press) 3. Saibal Kar, Prediman K Shah. Myocardium. Colour Handbook of Ischemic Heart Disease. Ed(Editors: Erling Falk, Prediman K Shah)(in press) 4. Ira Perry, Saibal Kar. Acute myocardial Infarction- complications Colour Handbook of Ischemic Heart Disease. 1st Ed(Editors: Erling Falk, Prediman K Shah) (in press) 5. Ira Perry, Saibal Kar. Acute myocardial Infarction- with normal coronary arteries Colour Handbook of Ischemic Heart Disease. 1st Ed(Editors: Erling Falk, Prediman K Shah) (in press) 6. Saibal Kar, Prediman K Shah. Impact of new percutaneous techniques of aortic valve replacement on cardiology/CV surgery practice. Transcatheter valve repair. 1st Edition(Editors: Ted Feldman, Ziyad Hijazi, (Martin Duntz 2005) 7. Saibal Kar and Wen-Loong Yeow. “Chapter 14: Procedural tips and tricks”. Percutaneous Mitral Leaflet Repair: MitraClip Therapy for Mitral Regurgitation. T. Feldman and F. St Goar, Eds. Informa Healthcare, 2012, pp 102-109 8. Mamoo Nakamura and Saibal Kar. “Transcatheter Occlusion of the Left Atrial Appendage”. Congenital and Structural Heart Disease, An Issue of Interventional Cardiology Clinics (The Clinics: Internal Medicine). K. Damien and ZM. Hijazi. Eds. Elsevier Health Sciences, 2013, pp 225-234. LETTERS TO THE EDITOR Reviews 1. 2. Kar Saibal, Kar CC: Mitral valve Prolapse Syndrome. Ind Heart J 1989 Sept; 41(5): 278-9 Kar CC, Kar Saibal: Hypertrophic Cardiomyopathy - An Overview. Ind Heart J 1988 March: 40(2): 72-5 ABSTRACTS 1. Kar CC, Maity AK, Ganguly K, Todi S, Kar S: Profile of aortoarteritis in Eastern India. World Congress of Cardiology, Sept 14-19, 1986, Washington D.C, USA. 2. Kar CC, Maity AK, Choudhury D, Chatterjee SS, Kar S: Studies on Carotid Sinus Hypersensitivity. The 9th Asian Pacific Congress of Cardiology, Feb 11-15, 1987, Term Follow Up and Complications. Auckland, New Zealand. 3. Maity AK, Kar S, Chatterjee SS, Choudhury D, Kar CC, Das MK: Carotid Sinus Hypersensitivity: An increasing indication for Pacing. Asian Pacific Congress of Cardiac Pacing, Aug 1989, Singapore Page 49 of 65 Curriculum Vitae 4. Saibal Kar, M.D, FAHA, FACC, FSCAI Maity AK, Das MK, Chatterjee SS, Guha S, Kar S, Kar CC: Pacing in India today, Asian Pacific Congress of Cardiac Pacing, August 1989, Singapore 5. Kar CC, Maity AK, Chatterjee SS, Guha S, Kar S, Das MK: Pacemaker malfunction. Asian Pacific Congress of Cardiac Pacing, August 1989, Singapore 6. Kar S, Sharma BK, Gupta A, Sagar S: Ocular Changes in nonspecific aortoarteritis. 10th Asian Pacific Congress of Cardiology, October 1991, Seoul, Korea 7. Kar S, Gupta A, Sharma BK, Sagar S: Ocular changes in Takayasu's Disease. Golden Jubilee Conference of the All India Ophthalmological Society, Feb 2-6,1992, New Delhi, INDIA 8. Kar S, Maity AK, Kar CC: Carotid Sinus Hypersensitivity (CSH) an Important cause of Syncope and Indication of Pacing in Elderly. 5th Asian Pacific Symposium on Cardiac Pacing and ectrophysiology, August 1-4, 1993, Tokyo, Japan 9. Kar S, Grover A, Varma JS, Khattria HN, Bidwai PS: Permane nt Pacing in Children: Long-Term Follow Up and Complications. Ind Heart J 1993; Abstract Issue Abst No 111 10. Dwivedi S, Varma JS, Khattri HN, Grover A, Kar S, Rao M, Sapru RP: Balloon Pulmonary Valvotomy in Patients of Valvular Pulmonary Stenosis with Right Heart Failure. Ind Heart J 1993; Abstract Issue Abst No 247 11. Kapardy PLN, Bagrahtta R, Khattri HN, Kar S, Grover A, Varma JS, Rao M, Sapru RP: Coronary Arteriographic Lesions in TMT Induced LV Dysfunction. Ind Heart J 1993; Abstract Issue Abst No 284 12. Kar S, Manolas E, Kumar P, Dick R, Lim Y, Rowe M: Direct coronary angioplasty for Acute Myocardial Infarction. Australia and New Zealand J of Medicine 1996; 27 (1): 101 13. Kar S, Manolas E, Kumar P, Dick R, Lim Y, Rowe M: Primary coronary angioplasty in Acute Myocardial Infarction. Ind Heart J; 48(5): 537 14. Kumar P, Kar S, Dick R, Manolas E, Rowe, Buxton B, Lim Y: Bailout surgery for failed PTCA. Ind Heart J 1996; 48(5): 486 15. Bhagaretta R, Kar S, Rowe M, Manolas E, Lim Y et al : Use of Abciximab(ReoproTM) in High-Risk Angioplasty(PTCA): Initial In –hospital Experience. Ind Heart J 1996; 48(5): 514 16. Kar S, Siegel R, , Eigler N, Robinson A, Goff B, Makkar R. Percutaneous Transluminal Septal Myocardial Ablation in Hypertrophic Obstructive Cardiomyopathy (HOCM) using Myocardial Contrast Echocardiography (MCE). An Initial experience: Early and Mid term results. Australian & New Zealand J of Med 1999;27:101(/Abstract) 17. Takizawa K, Hausleiter J, Finkelstein A, Kar S, Eigler N, Makkar R: Cilostazol inhibits stent thrombosis after oversized stenting in a porcine model. Am J Cardiol 2000;86(Suppl 8A) 120i Page 50 of 65 Curriculum Vitae 18. Saibal Kar, M.D, FAHA, FACC, FSCAI Aboul-Enein FA, Kar S, Hayes S, Makkar R, Lewin HC, Friedman J, Berman D: Influence of Angiographic Collaterals on Myocardial Perfusion in Patients With Chronic Total Occlusion of a Single Coronary Artery and No History of Myocardial Infarction. J Am Coll Cardiol 2001;37(Suppl A):1A-648A. 19. S. Kar, R.J. Siegel, J. Bergman, H.G. Voorman, H. Luo, A. Robinson, K. Varghese, N.Eigler, R. Makkar, Percutaneous transluminal septal myocardial ablation in hypertrophic Obstructive cardimyopathy (hocm) using myocardial contrast Echocardiography (MCE): a single-center experience. The J of Heart Dis 2 001;2 (Abstract issue): Abstr No 264. 20. H Honda, S Kar, T Honda, K Takizawa, T Meguro, M Fishbein, R Makkar, N Eigler, F Litvack. Everolimus Eluting Stents significantly inhibit neointimal hyperplasia in experimental pig coronary model. Am J Cardiol 2002; 90(Suppl 6A): 73H 21. T Honda, S. Kar, H. Honda, K. Takizawa, D. McClean, M. C. Fishbein, N. Eigler, F. Litvack. Stent-Based Delivery of Everolimus Leads to Complete Vessel Wall Healing without Toxicity in a 90 Day Porcine Model. Am J Cardiol 2002; 90(Suppl 6A): 80H 22. M J. Price , S Kar , D McClean , A. C. De Lara-Llarena, R Makkar. Sixty-Minute Balloon Inflation Occlusion of the Left Anterior Deescending Artery: results in a Predictable Porcine Model of Left Ventricular Dysfunction After Acute Myocardial Infarction. Am J Cardiol 2002; 90(Suppl 6A): 187H 23. D McClean, A Finkelstein, S Kar, K Takizawa, T Honda, N Baek, K Park, M C Fishbein, R Makkar, F Litvack, N Eigler. Local Drug Delivery Using a Stent with Programmable Pharmacokinetics In Vitro and in Porcine Coronary Arteries. Circ 2002; 106 (19):II-447. 24. Makkar R, Price M, Lill M, Takizawa K, Frantzen M, Fishbein M, Kar S, Kleisli T, Zheng J, Sharifi B, Qayyum M. Multilineage Differentiation of Transplanted Allogenic Mesenchymal Stem Cells Injected in a Porcine Model of Recent Myocardial Infarction Improves Left Ventricular Function. Circ 2002; 106 (19):II-34 25. S Kar, T Honda, D McClean, M. C. Fishbein, H. Honda, K. Takizawa, N Eigler, F Litvack.Elution Of Everolimus and Sirolimus From A Bio-Degradable Polymer Coated Stent Inhibits Neointimal Hyperplasia Without Inflammation or Toxicity. J Am Coll Cardiol 2003;41(Suppl A): 6A 26. Dougal McClean, Saibal Kar, Taku Honda, Michael C. Fishbein, Neal L. Eigler, Frank Litvack, Cedars-Sinai Medical Center, Los Angeles, CA. Stent-Based Delivery of Programmable Erodable Polymer Drug Release Systems are Nontoxic in Porcine Arteries. J Am Coll Cardiol 2003;41(Suppl A): 57A 27. S Zhou, Y Miyauchi, S Kangavari, M Miyauchi, S Kar, GM Suh, HS Karagueuzian, LS Chen, P Chen: Increased Transcardiac Nerve Growth Factor Concentration During Acute Myocardial Infarction in Dogs. PACE(Abstract) 28. MJ Price, M Franzten, S Kar, D McClean, S Guo, PK Shah, M Lill, J Forrester, BJ Martin, R.Makkar, Cedars Sinai Medical Center, Los Angeles, CA Usa Intravenous Mesenchymal Stem Cells Page 51 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Attenuate Left Ventricular Remodeling In A Porcine Model Of Reperfused Acute Myocardial Infarction. The J of Heart Disease (Abstract Issue)2003;3:2 29. S. Kar, T. Naqvi, M. Price, J. Aragon, R. Makkar, N. Eigler. Use Of Intracardiac Echocardiography For Guiding Device Closure Of Interatrial Communications. The J of Heart Disease (Abstract Issue)2003;3:31 30. S. Kar, D. McClean, J .Aragon, R. Makkar, F. Litvack, J. Whiting, N. Eigler. Implantable Physiologic Optimized Dosimeter For Treating Advanced Congestive Heart Failure. The J of Heart Disease (Abstract Issue)2003;3:45 31. S.Kar, D.McClean, J.Aragon, R.Makkar, F.Litvack, J.Whiting, N. Eigler. Cedars Sinai Medical Center. Implantable Left Atrial Physiologic Optimized Dosimeter for Treating Advanced Congestive Heart Failure. Am J Cardiol 2003;92(Suppl A): 199L 32. S Kar, MD, M Price MD, D. Mcclean MD, T. Naqvi MD, J. Aragon MD, H. Kotler RN, R. Makkar MD, N. Eigler . The Use of Intracardiac Echocardiography in help guiding Closure of Interatrial Communications. Am J Cardiol 2003;92(Suppl A):13L 33. R Virmani, R.Jones, S. Kar, T. Honda, D. McClean, M. Fishbein, N. Eigler, J. Royal, L Coleman, G. Cipolla. Everolimus and Sirolimus Drug-Eluting Stents Are Equally Effective at Reducing Neointimal Proliferation in a 28-Day Porcine Coronary Model. Am J Cardiol 2003;92(Suppl A): 178L 34. Saibal Kar, Joseph Aragon, Dougal McClean, Aamer Jamali, James Whiting, Frank Litvack, Neal Eigler. Chronic Implantation of Left Atrial Pressure Monitor Accurately easures Left Atrial Pressure in Porcine Model. J Am Coll Cardiol 2004;43(Suppl A):208A 35. Saibal Kar, Joseph Aragon, Alexander Paresky, Fermin Tio, John Shulze, Ronald Betts, Neal Eigler, Frank Litvack. Biolimus A9: A New Generation Rapamycin Analogue Inhibits Intimal Hyperplasia in a Porcine Model. J Am Coll Cardiol 2004;43(Suppl A):84A 36. Joseph Aragon, Saibal Kar, Alexander Paresky, Colin Watanabe, Amar Jamali, Frank Litvack, Neal Eigler. Optimization of Pharmacokinetic Vectors with a Programmable Paclitaxel Eluting Stent. J Am Coll Cardiol 2004;43(Suppl A):83A 37. Colin Watanabe, Joseph Aragon, Saibal Kar, Frank Litvack, Neal Eigler. Drug Eluting Stent with Multidimensional Programmable Kinetics. J Am Coll Cardiol 2004;43(Suppl A):83A 38. Richard E. Sinaiko, Mikele M. Bunce, Sepideh Farivar, Saibal Kar, Neal Eigler, Emma C. Wollschlager. Drug Eluting Stent Use May Negatively Impact the Economic Growth of a Hospital. A Single Center Case Study. J Am Coll Cardiol 2004;43(Suppl A):402A 39. Matthew J. Price, Chung-Chuan Chou, Malka Frantzen, Takashi Miyamoto, Saibal Kar, Dougal McClean, Suzhen Guo, Steve Lee, Prediman K. Shah, Bradley J. Martin, Michael Lill, James S. Forrester, Peng-Sheng Chen, Raj R. Makkar. Intravenous Mesenchymal Stem Cell Therapy Early After Reperfused Acute Myocardial Infarction Improves Left Ventricular Function and Alters Ventricular Electrophysiological Properties. J Am Coll Cardiol 2004;43(Suppl A):63A Page 52 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 40. Shinjo Sonoda, Eberhard Grube, Yoshihisa Shimada, Ali H. M. Hassan, Yasuhiro Honda, Charles Chan, Hidehiko Honda, Saibal Kar, Alexandra J. Lansky, Peter J. Fitzgerald. An Intravascular Ultrasound Analysis From FUTURE I, the First Human Experience Using Everolimus-Eluting Stents: Six- and Twelve-Month Results. J Am Coll Cardiol 2004;43(Suppl A):85A 41. Shinjo Sonoda, Eberhard Grube, Yoshihisa Shimada, Ali H. M. Hassan, Yasuhiro Honda, Charles Chan, Hidehiko Honda, Saibal Kar, Alexandra J. Lansky, Peter J. Fitzgerald. Effect of Everolimus-Eluting stents in preventing neointimal hyperplasia: An Intravascular Ultrasound Analysis from the FUTURE II Trial. J Am Coll Cardiol 2004;43(Suppl A):66A. 42. Sergio L. Kobal, Luca Trento, Simin Baharami, Kirsten Tolstrup, Tasneem Z. Naqvi, Bojan Cercek, Yoram Neuman, James Mirocha, Saibal Kar, James S. Forrester, Robert J. Siegel. J Am Coll Cardiol 2004;43(Suppl A):309A(abstract No. 1016-152) 43. Aamer H. Jamali, MD; Jason S. Bradfield, MD; Robert Goldberg, MD; Rajendra Makkar, Saibal Kar, MD. Drug Eluting Stent Use Is Associated With Increased Bare Metal Stent Use—Implications for Cost Effectiveness Analysis. Catheter Cardiovasc Interv 04;62:125 (abstract No D-3). 44. Simon Kangavari, Shengmei Zhou, Su-Chao Ding, Saibal Kar, C. Thomas Peter, Walter F. Kerwin, Charles D. Swerdlow, Eli Gang, Donna Gallik, Jeffrey S. Goodman, Yii-Der Ida Chen, Peng-Sheng Chen. Radiofrequency Catheter Ablation of Supraventricular Arrhythmias Increases Aortic and Cardiac Nerve Growth Factor Concentration in Humans. PACE 2004 (Abstract issue) 45. S Kar, A Jamali, J Aragon, D McClean, F Litvack, B Mann, J Whiting, N. Eigler. Chronic Left Atrial Pressure Monitoring in Pigs with HeartPOD™ Heart Failure Therapy System. 46. S Kar, A Jamali, J Aragon, F Tio, M Fishbein, F Litvack, B Mann, J Whiting, N. Eigler. Implantable HeartPOD™ System Allows Chronic Noninvasive Chronic Left Atrial Pressure Monitoring in a Porcine Model. Accepted PICCS meeting September 2004 47. Saibal Kar, Joseph Aragon, Fermin Tio, Ronald Betts, John Shulze, Sarah Reiver, Douglas Savage, Gordon Grant, Eitan Kimchi, Neal Eigler, Frank Litvack. Biolimus A9: A New Rapamycin Derivative Developed For Stent Applications Inhibits Intimal Proliferation In A Porcine Model. Am J Cardiol 2004;94(Suppl A): 151E. 48. Joseph Aragon, Dougal McClean, Saibal Kar, Aamer Jamali, Jon Bergman, James Whiting, Frank Litvack, Neal L. Eigler Equilibration of Airway Pressure and Pulmonary Capillary Wedge Pressure with Valsalva’s Maneuver During Right Heart Catheterization in Patients with Congestive Heart Failure. Accepted Heart Failure Society of America Meeting 2004 49. Joseph Aragon, Saibal Kar, Fermin Tio, Colin Watanabe, Aamer Jamali, Frank Litvack and Neal Eigler. Evaluation of Overlapped Cobalt Chromium Paclitaxel Eluting Stents with Programmable Release Kinetics. Am J Cardiol 2004;94(Suppl A); 28E 50. Joseph Aragon, Saibal Kar, Fermin Tio, Brett Trauthen Colin Watanabe, Aamer Jamali, Frank Litvack and Neal Eigler. Pre-clinical Analysis of PISCES Formulations: Histologic Results of Page 53 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI a Paclitaxel Eluting Stent with Programmable Release Kinetics. Am J Cardiol 2004;94(Suppl A): 28E 51. S Lee, E Daniels, T.Z. Naqvi, P.K. Shah, A. Shah, S.Kar, J.K.Frazer, R.W. Maclellan, M.Zhu, M.H. Hedrick, R. Makkar. Intracoronary Adipose Tissue-Derived Stem Cell Therapy Preserves Left Ventricular Function in a Porcine Model. Am J Cardiol 2004;94(Suppl A): 188E. 52. Saibal Kar, Taku Honda, Dougal McClean, Kaname Takizawa, Joseph Aragon, Hidehiko Honda, Cedars Sinai Medical Center, Los Angeles, CA; Michael Fishbein, Litvack Frank, Neal Eigler Everolimus And Sirolimus Are Identical At Preventing Intimal Thickening Over The Range Of Vascular Injury. Circulation 2004; 110(Suppl III): III-380. 53. S Kar, A Jamali, J Aragon, F Tio, M Fishbein, F Litvack, B Mann, J Whiting, N. Eigler. Implantable HeartPOD™ System Allows Chronic Noninvasive Chronic Left Atrial Pressure Monitoring in a Porcine Model. Accepted in Pediatric Interventional Cardiac Symposium, 2004. 54. Saibal Kar, Simon Kangavari, Shengmei Zhou, Hongmei Li, Su-Chao Ding, C.Yii-Der Ida Chen, Lan S. Chen, Peng-Sheng Chen. Elevation of Aortic and Coronary Artery Nerve Growth Factor following Acute Myocardial Infarction in Humans. J Am Coll Cardiol 2005; 45(Supplement A):94A 56. Joseph Aragon, Ryan Berg, Michael Lee, Eitan Kimchi, Kelley Davis, Honore Kotler, Raj Makkar, Tasneem Naqvi, Robert Siegel, Saibal Kar. Neurological Outcomes Following Percutatneous Closure of Inter-Atrial Communications. Catheterization and Cardiovascular Interventions 2005;65(1):93-94. 57. Joseph Aragon, Michael Lee, Saibal Kar, Neal Eigler, Raj Makkar. High Risk Coronary Intervention Using the Tandem Heart Percuataneous Left Ventricular Assist Device. Catheterization and Cardiovascular Interventions 2005;65(1):113 58. Michael Lee, Atman Shah, Joseph Aragon, Suhail Dohad, Saibal Kar, Raj Makkar. Intermediate Outcomes in Patients Undergoing Multivessel Percuatneous Coronary Intervention with Drug-Eluting Stents. Catheterization and Cardiovascular Interventions 2005; 65(1): 118. 59. Joseph Aragon, Saibal Kar, Ryan Berg, Eitian Kimchi, Alexander Parisky, Samantha Chaikin, Colin Watanabe, Aamer Jamali, Fermin Tio, Frank Litvack, Neal Eigler. Thin Walled Cobalt Chromium Paclitaxwl Eluting Stents Have No Restenosis Advangtage Over Stainless Steel Paclitaxel Eluitng Stents In A Porcine Model.Catheterization and Cardiovascular Interventions 2005;65(1):129. 60. Saibal Kar, Aamer Jamli, Joseph Aragon, Fermin Tio, Michael Fishbein, Frank Litvack, Brian Mann, James Whiting, Neal Eigler. Successful Direct Left ATrial Pressure Monitoring Via An Implantable Heartpod Device In Animal Models: A Potential Adjunct to Rhythm Management For Heart Failure Patients. Catheterization and Cardiovascular Interventions 2005; 65(1):130. 61. Lee MS, Shah AP, Jamali A, Kar S, Dohad S, Aragon J, Makkar RR. Drug-eluting stenting is superior to bare-metal stenting in saphenous vein grafts (abstract). TCT Asia Pacific 2005. Am J Cardiol 2005;95(Suppl A):3A. Page 54 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 62. Lee MS, Shah AP, Friedman J, Dang N, Bobo D, Fariabi S, Kar S, Aragon J, Caraang C, Berman D, Makkar RR. Characterization of the coronary venous system with contrast-enhanced electron beam computed tomography (abstract). TCT Asia Pacific 2005. Am J Cardiol 2005;95(Suppl A): 18A. 63. Lee MS, Shah AP, Friedman J, Dang N, Bobo D, Fariabi S, Kar S, Aragon J, Caraang C, Berman D, Makkar RR. Contrast-Enhanced Electron Beam Computed Tomography Provides Detailed Characterization of the Coronary Venous System (abstract). Catheterization and Cardiovascular Interventions 2005; 65(1) 64. Saibal Kar, Ryan Berg, Gordon Grant, Vladimir Royter, Joseph Aragon, John Shulze,Ronald Betts, Michael C Fishbein. Safety of Biolimus A9 Delivered from a Bioresorbable Polymer Coated Stent in a 90 Day Porcine Model. Am J Cardiol 2005;96(Suppl 7A):212H 65. Joseph Aragon, Ryan Berg, Saibal Kar, Vladimir Royter, Renu Vermani, Neil Eigler, Frank Litvack. Pimecrolimus Eluting Cobalt Chromium Stent Decreases Inflammation and Neointimal Proliferation in a Porcine Model. Am J Cardiol 2005;96(Suppl 7A):23H 66. Joseph Aragon, Ryan Berg, Saibal Kar, Vladimir Royter, Renu Vermani, Neil Eigler, Frank Litvack A Pimecrolimus and Paclitaxel Dual Drug-Eluting Stent: A Synergistic Response From Drugs With Different Mechanisms and Different Release Kinetics From the COSTAR Stent Platform. Am J Cardiol 2005; 96(Suppl 7A):8H 67. Michael S Lee, Nikil Kapoor, Faizi Jamal, Lawrence Czer, Joseph Aragon, James Forrester, Saibal Kar, Sohail Dohad, Robert Kass, Neal Eigler, Alfredo Trento, Prediman K Shah, Raj Makkar. Comparison of coronary artery bypass surgery with percutaneous coronary intervention with drug eluting stents for unprotected left main coronary artery disease. Am J Cardiol 2005;96(Suppl 7A):201H 68. David Smyth, Jay LT Ritzema-Carter, Richard W Troughton, Iain C Melton, Ian Crozier, Saibal Kar, James Whiting, Neal Eigler. Dynamic Myocardial Ischemia Secondary to Left Circumflex Artery Stenosis Documented by a Novel Permanent Implantable Left Atrial Pressure Sensing Device. Am J Cardiol 2005;96(Suppl 7A): 192H 70. Saibal Kar, Aamer Jamali, Roderick Tung, Jeffrey Levisman, Fermin Tio, Michael C Fishbein, James Whiting, Neal Eigler. Successful Direct Left Atrial Pressure Monitoring And Fossal Pacing Via Implantable HEARTPOD Device In Animal Models. J Am Coll Cardiol 2006;47(Suppl A): 78A. 71. Jay L Ritzema-Carter, Iain C Melton, Ian G Crozier, Saibal Kar, Neal Eigler, James Whiting, Henry Krum, William T Abraham, Richard W Troughton. First Human Experience With A New Left Atrial Pressure Monitoring Device: Validation With Simultaneous Pulmonary Artery Occlusion Pressure In Subjects With Heart Failure. J Am Coll Cardiol 2006;47(Suppl A): 78A 72. Saibal Kar, Aamer Jamali, Werner Haffelfinger, Brian Mann, James Whiting, Neal Eigler. A New Flexible Transeptal Catheter System Allows Access Into The Left Atrium From The Femoral Or Jugular Venous Approach. 55th ACC I2(Abstract) Page 55 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 73. Kupferwasser LI, Amorn AM, Lee MS, Kar S, Cercek B, Dohad S, Kapoor N, Makkar R. Comparison of sirolimus- and paclitaxel-eluting versus bare metal stenting in an unselected patient population with acute myocardial infarction. 55th Annual Scientific Session of the American College of Cardiology, Atlanta, 2006, abstract 2912-77 74. Saibal Kar, Vladimir Royter, Gordon Grant, John Shulze, Douglas Savage, Michael C Fishbein. Non Polymer Elution Of Biolimus From A Stent Inhibits Intimal Hyperplasia in A Porcine Model. J Am Coll Cardiol 2007;49(9)Suppl B: 28B. 75. Melissa Slivka, Bina Ahmed, Ryan Berg, Donna M. Polk, Saibal Kar, Maura Paul-Labrador, Raj Makkar, Leslee J. Shaw, Margo B. Minissian, Noel Bairey Merz Myocardial Ischemia and Open Coronary Arteries in Women: Etiological Mechanisms. J Am Coll Cardiol 2007; 49(9)Suppl A 78. James Hermiller, Saibal Kar, Michael Rinaldi, Howard Herrmann, Peter Fail, Patrick L Whitlow, Eric Horlick, Elyse Foster, Don Glower, Ted Feldman on behalf of the EVEREST Investigators. Percutaneous Mitral Repair with the MitraClip™ Device for Functional Mitral Regurgitation: Acute Success and 12-Month Durability. Am J of Cardiol 2007; Suppl 8A:216L(TCT -559) 79. Michael Rinaldi, Saibal Kar, James Hermiller, Richard W Smalling, Bill Gray, John Carroll, Andrew Wang, Elyse Foster, Don Glower, Ted Feldman. Significant Reverse Remodeling of the Left Ventricle One Year After Percutaneous Mitral Repair with the MitraClip™ Device. Am J of Cardiol 2007;100 Suppl 8A: 57L (TCT -123) 80. Anthony J White, Gautam Kedia, James Mirocha, Michael S Lee, Gregory Fontana, Alfredo Trento, Saibal Kar, Suhail Dohad, Prediman K Shah, Raj Makkar. Comparison of Coronary Artery Bypass Surgery and Percutaneous Drug-eluting Stent Implantation for Treatment of Left Main Coronary Artery Stenosis: Analysis by Propensity Score Adjustment and by Surgical Risk. Am J of Cardiol 2007;100 Suppl 8A: 97L (TCT -233) 81. Blasé A Carabello, Saibal Kar, Michael Rinaldi, James Hermiller, Vishwajeth Bhoopalam, Azam Anwar, Tanvir Bajwa, Mike O’Donnell, Don Glowere, Ted Feldman. Significant Reverse Remodeling of the Left Ventricle One Year After Percutaneous Mitral Valve Repair with the MitraClip Device in Patients with Pre-existing Systolic LV function. Circulation 2007; Suppl II Vol 116: II-357 (abstract No. 1698) 82. Shufelt CL, Kar S, Slivka M, Thomson L, Yang Y, Berman D, Polk D, Tolstrup K, Bairey Merz CN. Cardiac magnetic resonance imaging and coronary reactivity testing: A useful noninvasive tool. Poster, Tuesday April 1, 2008, 11-12 noon presentation, Hall A, McCormick Place, Session #1031 83. Polk D, Shufelt C, Yang Y, Kirschner J, Paul-Labrador M, Williams, Kar S, Tolstrup K, Bairey Merz CN. Angina, open arteries and endothelial dysfunction in women With suspected ischemia. Poster, Monday March 31, 2008, 10-11 am presentation, McCormick Place, South Hall 84. Slivka M, Shufelt C, Yang Y, Thomson L, Kar S, Shaw L, Berman D, Ahmed B, Tolstrup K, Page 56 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Bairey Merz CN. Is cardiac magnetic resonance imaging a useful tool in the diagnosis of women with microvascular angina. Poster, Tuesday April 1, 2008, 11-12 noon presentation, Hall A, McCormick Place, Session #1031 85. James Hermiller, MD; Saibal Kar, MD; Peter Fail, MD; Tanvir Bajwa, MD; Richard Smalling, MD; John Lasala, MD; Scott Lim, MD; Robert Kipperman, MD; Howard Herrmann, MD; Patrick L Whitlow, MD; Elyse Foster, MD; Don Glower, MD; and Ted Feldman, MD. Percutaneous Mitral Repair with the MitraClip® Device for Functional Mitral Regurgitation: Acute Success and One-Year Durability in the Initial EVEREST Cohort. Accepted ACC March 2008. Late Breaking clinical trials 86. Howard C Hermann, Saibal Kar, Peter Flail, Jason Rogers, Andrew Wang, Andrew Berke, Paul Kramer, S Chiu Wong, Scott Lim, Elyse Foster, Don Glower, Ted Feldman on behalf of the EVEREST investigators. Stability of Mitral Valve Area and Gradient Following Percutaneous Repair of Mitral Regurgitation with MitraClip Device.excc . J Am Coll Cardiol 2008;51(10)(Suppl B): B79 87. Hursh Naik, Robert Weiss, Tarun Chakravarty, Anthony J White, James Forrester, Saibal Kar, and Raj Makkar Abstract 2522: A Meta-analysis Of 2587 Patients Treated With Percutaneous Coronary Intervention Or Coronary Artery Bypass Grafting For Unprotected Left Main Coronary Artery Stenosis. Circulation, Oct 2008; 118: S_737 88. Norio Tada, MD; Gordon Grant; Alexander Black, MB,BS; Renu Virmani, MD; Saibal Kar, MD Polymer-Free Biolimus A9 Eluting Stent Demonstrates More Sustained Intimal Inhibition, Improved Healing and Reduced Inflammation in Comparison to a Polymer-Coated Sirolimus Eluting Cypher Stent in a Porcine Model. J Am Coll Cardiol 2009; Abstract Issue 89. Norio Tada, Gordon Grant, John Shulze, Renu Virmani, Saibal Kar. Short and Long Term Evaluation of Polymer Free Biolimus A9 Eluting Stent Compared to Sirolimus Eluting Stent in Porcine Model. 73rd Annual Meeting of Japanese Circulation Society; Osaka, March 2009 . Circ J 2009;73(Suppl. I):433 90. Norio Tada, Saibal Kar. Twelve Months Following Percutaneous Mitral Valve Repair Using the Edge-to-Edge Repair with the MitraClip TM Device. 73rd Annual Meeting of the Japanese Circulation Society, Osaka, March 2009.(Circ J 2009:73(Suppl.I): 344 abstract) 91. Janet Wei, Louise Thomson, Chrisandra Shufelt, YuChing Yang, Edward Gill, Margo Minissian, Saibal Kar, Daniel Berman, C. Noel Bairey Merz.Diastolic Dysfunction by Cardiac Magnetic Resonance Imaging in Women With Open Coronary Arteries and Microvascular Dysfunction. Annual Meeting of the American College of Cardiology: March, 2009. 92. Anita Phan, Supurna Chowdhury, Margo Minissian, Chrisandra Shufelt, Saibal Kar, Doris Taylor, Vera Regitz-Zagrosek, Noel Bairey Merz, Eduardo Marban Circulating Endothelial Progenitor Cells in Women with Microvascular Dysfunction. Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009. Page 57 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 93. Saibal Kar, Patrick Whitlow, Wesley Pedersen, Scott Lim, Robert Kipperman, Richard Smalling, Tanvir Bajwa, Howard Hermann, John Lazala, Paul Kramer, James T Maddux, Ted Feldman, Don Glower, Blaise A Carabello, Elyse Foster. Successful Percutaneous MitraClip® Therapy Results in Favorable Septo-Lateral Mitral Annular Diameter and Left Ventricular Remodeling in High Risk Surgical Patients with Functional Mitral Regurgitation. American J of Cardiol 2009: 104(Suppl 6A): 33D. 94. Scott Lim, Blasé A Carabello, Saibal Kar, Allan Schwartz, Richard Smalling, Catalin Loghin, Jason Rogers, Damon Kwon, David Warth, Paul Grayburn, Stam Lerakis, Steven Bailey, Donald Glower, Ted Feldman, Elyse Foster. Significant Reverse Left Ventricular Remodelling One Year After Successful MitraClip® Therapy. American J of Cardiol 2009: 104(Suppl 6A): 34D. 95. Brett M Wertmann, Mamta H Buch, Raj Makkar, Nicola D’Attellis, Saibal Kar, Acute Hypoxemia Secondary to Right-to-Left Shunting Across the Interatrial Septum Following Deployment of an LA Appendage Closure Device. ACC i2 Summit 2010. 96. Robert J Siegel, Gila Perk, Takahiro Shiota, Itzhak Kronzon, James Slater, Saibal Kar, Asma Hussaini, Simon Biner. Catheter-Based, Percutaneous Mitral Valve Clipping-The Added Value of Real-Time Transesophageal Echocardiography. J Am Coll Cardiol 2010;55(issue 10, suppl 1)A64.E607 97. Saibal Kar; Patrick Whitlow; Wes Pedersen; Scott Lim; Robert Kipperman; Richard Smalling; Tanvir Bajwa; Howard Herrmann; John Lasala; Paul Kramer; James Maddux; Ted Feldman; Don Glower; Blase Carabello; Elyse Foster, on behalf of the EVEREST investigators Successful MitraClip® Therapy Results in Favorable Septo-Lateral Mitral Annular Diameter and Left Ventricular Remodeling in High Risk Surgical Patients with Functional Mitral Regurgitation. Cath Cardiol Interventions 2010;75(suppl):S147 98. Saibal Kar et al on behalf of EVEREST II trial. High Risk Registry EVEREST II Trial:One year results. SCAI Meeting. San Diego, 2010. 99. Ted Feldman, Laura Mauri, Saibal Kar, Michael Rinaldi, Peter Fail, James Hermiller, Richard Smalling, William Gray, Andrew Wang, Howard Hermann, Jason Rogers, John Lasala, Tanvir Bajwa, Paul Greyburn, Wesley Pedersen, Elyse Foster, Alfredo Trento, Donald Glower. EVEREST II Randomized Clinical Trial: A Critical Assessment of the Safety Data in Patients treated with the MitraClip. J Am Coll Cardiol.2010;56(13)(Suppl B): Abstract No 99. 100. Scott Lim, Ted Feldman, Saibal Kar, Michael Rinaldi, Peter Fail, James Hermiller, Richard Smalling, William Gray, Andrew Wang, Howard Hermann, Jason Rogers, John Lasala, Tanvir Bajwa, Paul Greyburn, Wesley Pedersen, Brian Whisenant, Andrew Burke, Michael O’Donnell, Patrick Whitlow, Robert Siegel, Alfredo Trento, Donald Glower, Elyse Foster on behalf of the EVEREST II Investigators. EVEREST II Randomized Clinical Trial: Significant Reverse Left Ventricular Remodelling One Year Following MV Surgery and MitraClip Therapy. J Am Coll Cardiol.2010;56(13)(Suppl B): Abstract No 101 101. James Hermiller, Saibal Kar, Michael Rinaldi, Scott Lim, Richard Smalling, William Gray, Andew Page 58 of 65 Curriculum Vitae . Saibal Kar, M.D, FAHA, FACC, FSCAI Wang, Howard Herrmann, Jason Rogers, John Lasala, Tanvir Bajwa, Paul Greyburn, Wesley Pedersen, Brian Whisenant, Andrew Burke, Michael O’Donnell, Patrick Whitlow, Robert Siegel, Alfredo Trento, Donald Glower, Ted Feldman, Elyse Foster. EVEREST II Randomized Clinical Trial: Clinical Benefti by MR Grade in Patients One Year following Successful MitraClip Therapy. J Am Coll Cardiol.2010;56(13)(Suppl B): Abstract No 107. 102. Mehran Khorsandi, Henry Bourang, Michael Shenoda, Sepehr Fariabi, Rajendra Makkar, Saibal Kar. Coronary Bifurcation Lesions Treated with the Novel Advanced Bifurcation Systems TM Dedicated Stent: Animal Experience. J Am Coll Cardiol.2010;56(13)(Suppl B): Abstract No 134. 103. Mehran Khorsandi, Alex Abizaid, Sameer Dani, Michael Shenoda, Henry Bourang, Ricardo Costa, Saibal Kar, Rajendra Makkar. Coronary Bifurcation Lesions Treated with the Novel Advanced Bifurcation-SystemTM Dedicated Stent: Preliminary Results of the Prospective Multicenter First in Man Experience. J Am Coll Cardiol.2010;56(13)(Suppl B): Abstract No 142. 104. Saibal Kar, David Holmes, Shephal K Doshi, Petr Neuzil, Vivek Y Reddy. The Safety of Percutaneous Left Atrial Appendage Closure in Stroke Prevention in Atrial Fibrillation Patients: Is there Evidence for a Learning Curve. J Am Coll Cardiol.2010;56(13)(Suppl B): Abstract No 472. 105. 106 TCT 2010 Saibal Kar on behalf of the EVEREST II investigators. MitraClip Therapy Demonstrates Continued Clinical Benefit and Favorable Left Ventricular Remodeling at Two Years in High Risk Surgical Patients with Significant Mitral Regurgitation: Analysis of the EVEREST II High Risk Registry. J Am Coll Cardiol 2011;57(issue 14 suppl 1): E1308 106. Saibal Kar, Mamta Buch, Brett Wertmann, Asma Hussaini, Rajendra Makkar, Robert Siegel. The Safety and Efficacy of Percutaneous Left Atrial Appendage Closure for Stroke Prevention in Atrial Fibrillation Patients. The Experience of a Large Volume Single Center in the PROTECT AF study. ACC Poster Session, New Orleans, April 5, 2011. 107. David Holmes Jr, Saibal Kar, Shephal Doshi, Petr Neuzil, Vivek Reddy.The Safety of Percutaneous Left Atrial Appendage Closure for Stroke Prevention in Atrial Fibrillation(AF) Patients: Is there Evidence for a Learning Curve. J Am Coll Cardiol 2011;57(use 14, Suppl 1): E1682. 108. Mehran Khorsandi, Alex Abizaid, Sameer Dani, Sepher Fariabi, Henry Bourang, Ricardo Costa, Saibal Kar, Raj Makkar. Advanced Bifurcation Systems™ Novel Modular Platform in Treatment of Coronary Bifurcation Disease,Initial Resuls of the Multicenter, First-in-Human Feasibility Trial. J Am Coll Cardiol 2011;57(issue 14, suppl 1):E1995. 107. Saibal Kar, Michael Rinaldi, Scott Lim, Ted Feldman. EVEREST II Realism: A Continued Access Study to Evaluate the Safety and Effectiveness of the MitraClip Device: Demographics and Procedural Outcomes. Catheterization and Cardiovascular Interventions 2011;77:abstract E34 108. Rinaldi M, Kar S, Lim S, Feldman T. EVEREST II Realism: A Continued Access Study ot Evaluate the Safty and Effectiveness of the MitraClip Device: Analysis of a 6 MonthPatient Cohort. Page 59 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Catheterization and Cardiovascular Interventions 2011;77:S134. SCAI 2011 109. Ibebuogu U, Makkar R, Harrison D, Kwarteng C, Mirocha J, Hussaini A, Singh S, Dohad S, Cercek B, Khorsandi M, Kar S. Comparison Between Transradial and Transfemoral Percutaneous Coronary Intervention in Acute ST-elevation Myocardial Infarction. Catheterization and Cardiovascular Interventions 2011;77:S27. Saibal Kar, Radial artery study. SCAI 2011. 110. Khorsandi M, Abizaid A, Dani S, Bourang H, Costa R, Kar S, Makkar R. Advanced bifurcation systems mother-daughter platform, a novel system in treatment of coronary bifurcation lesions:preliminary results of the prospective, multicenter first-in-man experience. Eurointerventions 2011;(Vol 7 Suppl M):M127 111. Kar S, Holmes D, Doshi S, Neuzil P, Reddy V. The safety of percutaneous left atrial appendage closure for stroke prevention in atrial fibrillation patients: is there evidence for a learning curve? Eurointerventions 2011;(Vol 7, Suppl M): M231 112. Kar S, Reddy V, Turi Z, Doshi S, Sieveret H, Buchbinder M, Holmes D. Left atrial appendage closure and the Protect AF trial: results at 1500 patient-years of follow-up. Eurointerventions 2011;(Vol 7 Suppl M):M232. 113. Mehran J Khorsandi, Alex Abizaid, Sameer Dani, Henry Bourang, Ricardo Costa, Saibal Kar, Raj Makkar. Advanced Bifurcation Systems Mother-Daughter Platform in Treatment of Complex Coronary Bifurcations: Prospective Mutlicenter First-in-Man Feasibility Experience. J Am Coll Cardiol 2012; 59(Suppl A):A20 (abstract No 2524. 114. Shahryar Chowdhury, Girish Shirali, Ziyad Hijazi, Saibal Kar, Raj Makkar, John Rhodes, Michael Mullen, Qi-Ling Cao, Jodi Akin. Early Echocardiographic Changes after Percutaneous Implantation of the Edwards SAPIEN Transcatheter Heart Valve in the Pulmonic Position. J Am Coll Cardiol 2012;59(Suppl A);A197, abstract no 1136-134. 115, Takeji Saito, Masaki Izumo, Yoko Fukuoka, Azusa Furugen, JUN TANAKA, Kenji Harada, Swaminatha Gurudevan, Kirsten Tolstrup, Robert Siegel, Saibal Kar, Takahiro Shiota. The Evaluation of Iatrogenic Atrial Septal Defect After Catheter-based Mitral Valve Clip Repair:Two-and Three-dimensional Echocardiographic Study. J Am Coll Cardiol 2012;59(Suppl A);A271(abstract no 1091-16 116. R David Anderson, Puja Mehta, Janet Wei, Delia Johnson, John Petersen, Eileen Handberg, Chrisandra Shufelt, Saibal Kar, Bruce Samuels, Babak Azarbal, Kamlesh Kowthawade, Sheryl Kelsey, Barry Sharaf, Leslie Shaw, Carl Pepine, C Noel Bairey Merz. J m Coll Cardiol 2012;59(Suppl A):A365( Abstract No 1200-138 117. Saibal Kar, Shephal Doshi, David Holmes, Sven Mobius-Winkler, Vivek Reddy, Gerhard Schuler, Peter Sick, Horst Sievert. Watchman Left Atrial Appendage Closure in atrial fibrillation Patients 75 years or greater: a Sub-Analysis of the PROTECT AF Study. J Am Coll Cardiol. 2012;60(17_S): B 26 118. Anita Asgar, Paul Khairy, Raoul Bonan, Anique Ducharme, Saibal Kar. Safety and Efficacy of the MitraClip For The Treatment of Patients With A Dilated Left Ventricle And Functional Mitral Regurgitation. J Am Coll Cardiol.2012;60(17_S): B27-B28 119. Asma Hussaini, Wen Loong Yeow, Takashi Matsumoto, Mamoo Nakamura, Hassan Jlaihawi, Raj Page 60 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Makkar, Saibal Kar. Large 22 to 24 Fr femoral vein hemostasis with a subcutaneous stitch or a double Perclose closure is effective and safe. J Am Coll Cardiol.2012;60(17_S): B 120 120. D Scott Lim, Saibal Kar, Patrick Whitlow, Michael Argenziano, Alfredo Trento, Gorav Ailawadi, Donald Glower, Ted Feldman.Effectiveness of Transcatheter Mitral Valve Repair in Degenerative Mitral Regurgitation in High Surgical Risk Patients. J Am Coll Cardiol.2012;60(17_S):B 229 121. Takashi Matsumoto, Wen Loong Yeow, Asma Hussaini, Mamoo Nakamura, Moody Makar, Swaminatha V. Gurudevan, Robert Siegel, Saibal Kar. Procedural success is improved with a 2nd MitraClip placement without additional complications. J Am Coll Cardiol.2012;60(17_S): B 231-B232 122. Wen Loong Yeow, Mamoo Nakamura, Takashi Matsumoto, Hassan Jlaihawi, Asma Hussaini, Moody Makar, Swaminath V. Gurudevan, Robert Siegel, Saibal Kar.The MitraClip Procedure For Functional Mitral Regurgitation Results in A Significant Change In Procedural Hemodynamics. J Am Coll Cardiol.2012;60(17_S): B 231-B232 123. Jun Tanaka, Takashi Matsumoto, Wen Loong Yeoew, Kenji Harada, Javier Berdejo, Kentaro, Shibayama, Kazumasa Harada, Saibal Kar, Takahiro Shiota. Evaluation of Mitral Valve Area after MitraClip Procedure: A Real-Time 3D Transesophageal Echocardiographic Study. J Am Coll Cardiol 2013;61(10 Suppl A):A217 124. Puja Mehta, Tara Sedlak, Tanya Kenkre, B Delia Johnson, Chrisandra Shufelt, John Petersen, Babak Azarbal, Bruce Samuels, R. Anderson, Leslee Shaw, Saibal Kar, Eileen Handberg, Sheryl Kelsey, Carl Pepine, C. Noel Bairey Merz. Angina and Anti-anginal Therapy in Women with Signs, and Symptoms of Ischemia and No Obstructive Coronary Artery Disease.J Am Coll Cardiol 2013;61(10 Suppl A):A366 Abstract No 1115-98 125. Takashi Matsumoto, Wen-Loong Yeow, Asma Hussaini, Mane Arabyan, Amin Manuchehry, Mamoo Nakamura, Moody Makar, Swaminatha Gurudevan, Takahiro Shiota, Alfredo Trento, Saibal Kar. Preoperative Pulmonary Hypertension Has an Adverse Effect in Patients with Functional Mitral Regurgitation Undergoing the MitraClip Procedure. J Am Coll Cardiol 2013;61(10 Suppl A):A473; Abstract No 2114-248B 126. Mane Arabyan, Wen-Loong Yeow, Takashi Matsumoto, Asma Hussaini, Takahiro Shiota, Swaminatha Gurudevan, Vinny Ram, Rehan Kanji, Alfredo Trento, Saibal Kar. High Mortality in Screened Patients with Functional Mitral Regurgitation Awaiting MitraClip Procedure.J Am Coll Cardiol 2013;61(10 Suppl A):A481. Abstract No 1111-77 127. Wen-Loong Yeow, Takashi Matsumoto, Robert Siegel, Asma Hussaini, Mamoo Nakamura, Moody Makar, Amin Manuchehry, Rehan Kanji, Alfredo Trento, Saibal Kar. Acute Changes in Cardiac Output following MitraClip Procedure Are a Powerful Predictor of Clinical Outcomes. J Am Coll Cardiol 2013;61(10 Suppl A):A481. Abstract No 1111-78 128. Scott Lim, Saibal Kar, Peter Fail, Brian Whisenant, William Gray, Tanvir Bajwa, Michael Rinaldi, Robert Kipperman, John Williams, Richard Smalling, James Hermiller, Paul Grayburn, Gorav Allawadi, Neil Weissman, Elyse Foster, Donald Glower, Ted Felman. The EVEREST II High Surgical Risk Cohort: Effectiveness of Transcatheter Reduction of Significant Mitral Regurgitation in High Surgical Risk Patients. J Am Coll Cardiol 2013;61(10 Suppl A):A489. Abstract No. 922-5 129. Saibal Kar, D Lim, Richard Smalling, Brian Whisenant, Chidambaram Rammohan, Peter Fail, Michael Rinaldi, James Hermiller, Howard Herrmann, Robert Kipperman, John Williams, Carlos Ruiz, William Gray, James Slater, Neil Weisman, Elyse Foster, Ted Feldman.J Am Coll Cardiol 2013;61(10 Suppl A):A489. Abstract No.922-6 Page 61 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI 127. Kar S, Hou D, Russ J, Werner D, Swanson L, Tischler B, Huibregtse B, Virmani R.Biology response following watchman and Amplatzer cardiac plug implantation in a canine let atrialappendage model. EuroPCR2013, Paris, May 24, 2013. 128. Reddy VY, Doshi SK, Sievert H, Buchbinder M, Neuzil P, Huber K, Kar S, Halperin J, Whisenant B, Swarup V, Holmes D. Long Term Results of PROTECT AF:The Mortality Effects of Left Atrial Appendage Closure versus Warfarin For Stroke Prophylaxis in AF. Heart Rhythm Society Meeting, Denver, Colorado, US, May 9, 2013 129 Saibal Kar, MD, Shephal Doshi, Vijay Swarup, Kenneth Tucker, Brian Whisenant, Rodney Horton, Vivek Reddy, Maurice Buchbinder, Horst Sievert, David Holmes. Long Term Efficacy of Left Atrial Appendage Closure with WATCHMAN® Device. European Society of Cardiology, Amsterdam, Sept 1, 2013 130. Alfredo Trento, Wen Loong Yeow, Takashi Matsumoto, Asma Hussaini, Swaminatha V. Gurudevan,Takahiro Shiota, Saibal Kar. Outcomes of surgery are preserved following the MitraClip Procedure. Transcatheter Therapeutics, San Francisco, October 29, 2013. J Am Coll Cardiol. 2013;62(18_S):B28-B29. 131. Saibal Kar, Shephal Doshi, Vjendra Swarup, K. Tucker, Brian Whisenant, Rodney Horton, Vivek Reddy, Maurice Buchbinder, David Holmes Jr. Long Term Event Rates of Left Atrial Appendage Closure with WATCHMAN Device Stratified by CHADS2 Score. Transcatheter Therapeutics, Sanf Francisco, Oct 2013. J Am Coll Cardiol 2013;62(18_S):B31 132 Wen Loong Yeow, Takashi Matsumoto, Asma Hussaini, Robert Siegel, Pooja Khanolkar, Alfredo Trento, Swaminatha V. Gurudevan, Moody Makar, Saibal Kar. Tethering Area is an Important Predictor of Recurrent Mitral Regurgitation Following the MitraClip Procedure. Transcatheter Therapeutics, San Francisco, October 2013. J Am Coll Cardiol. 2013;62(18_S):B215 133. Takashi Matsumoto, Jun Tanaka, Wen Loong Yeow, Asma Hussaini, Mamoo Nakamura, Moody Makar, Alfredo Trento, Takahiro Shiota, Saibal Kar. Three-dimensional color Doppler transesophageal echocardiography is helpful in determining the number of MitraClip devices. Transcatheter Therapeutics, San Francisco, Oct 2013. J Am Coll Cardiol 2013;62(18_1):B214 134. Saibal Kar, Scott Lim, Vivek Rajagopal, Tanvir Bajwa, Ramon Quesada, John Carroll, Elyse Foster, Neil Weissman, Alfredo Trento, Michael Mack, Donald Glower, Ted Feldman. Percutaneous Leaflet Therapy of Severe Primary Mitral Regurgitation: Totality of Evidence From the EVEREST II Randomized, Continued Access, and High Risk Clinical Programs. Transcatheter Therapeutics, San Francisco, Oct 2013. J Am Coll Cardiol 2013;62(18_S):B29. 135. Michael Rinaldi, Saibal Kar, D. Scott Lim, James Hermiller Jr, Richard Smalling, James Slater, Elyse Foster, Ted Feldman. Percutaneous Reduction of Severe Mitral Regurgitation in Elderly High Surgical Risk Patients. J Am Coll Cardiol 2013;62(18_S):B30. 136. Dongming Hou, Saibal Kar, Russell M. Jones, Dennis Werner, Lynne Swanson, Brian Tischler, Barbara A. Huibregtse, Renu Virmani. Anatomical Effect on Left Atrial After Transcatheter Left Atrial Appendage Devices: Watchman and Amplatzer Cardiac Plug in a Canine Model. J Am Coll Cardiol 2013;62(18_S):B242. OTHER ACTIVITIES Performed Interventional procedures on children In Ciudad Obregon, Mexico as a part of charity. April 2-4, 2005 Page 62 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI The devices were donated by AGA Co. The other sponsors were Liga’s Children Heart Program And Rotary Club.( I went as a team of 3 doctors, Myself, Dr Siegel, and Dr Watanabe,) Our work was mentioned in the local media, and we are trying to make this mission and annual event Performed Interventional procedures on children December 9-11, 2005 In Ciudad Obregon, Mexico as a part of charity. The devices were donated by AGA Co. The other sponsors were Liga’s Children Heart Program And Rotary Club.( I went as a team of 3 doctors, Myself, Dr Siegel, and Dr Wong, and Dr Ryan Berg,) Our work was mentioned in the local media, and we are trying to make this mission and annual event Performed Interventional procedures on 4 children December 9-11, 2006 In Ciudad Obregon, Mexico as a part of charity. The devices were donated by AGA Co. The other sponsors were Liga’s Children Heart Program And Rotary Club.( I went as a team of 3 doctors, Myself, Dr Siegel, and Dr Fernando Mendoza, Dr ). This is an inspiring experience. We also taught the physicians to do the procedures. Faculty Controversies in the Treatment of Cardiovascular Disease, October 6th to 7th, 2005. Los Angeles, CA PROCTORSHIP 1. Savacor/St Jude Medical Dr Iain Melton, Christchurch Hospital, March 2005, May 2006 Dr Stewart, Greenlane Hospital, Auckland, New Zealand, November 2005, May 2006 Dr Anthony Walton, Alfred Hospital, July 15, 2005, November 2005, May 2006 Dr Charles Love, Dept of Cardiology, OSU, Columbus, Ohio, November 7, 2005 Dr Paul Terstein, and Dr Johnson, Scripps Green Hospital, San Diego, CA 2. NMT Medical Dr Paul Ho, Kaiser Hospital, Honolulu, Hawaii, Sept 2005 Dr. Richard Heuser, Phoenix, Arizona Dr. Sanjiv Goyal, Las Robles Hospital, Thousand Oaks, CA Dr Vishwa Dev, Las Robles Hospital, Thousand Oaks, CA Dr Neal Klein, Phoenix, Arizona Dr Joseph Ruggio Dr John Badado, Sunrise Hospital, Las Vegas, Nevada Dr Steve Bailey, San Antonio Hospital, Texas Dr Geoffrey Kuntz, Alberquque, New Mexico. Dr Marko Noc, December 6-8, Medicor, Izola, Slovenia, -EU. 3. AGA Medical Dr Arthur Lussararian Dr Aijaz Hashmi, Loma Linda University. Dr Asan Chowdhury, Las Vegas. Dr Ulrich Luft and Dr Molly Szerlip…..University of Tuscon, Arizona : Atrial Septal Defect Closure. January 23, 2010. Dr Jim Joy, El Camino Hospital, CA. Post MI Ventricular Septal defect closure Dr Marko Noc, Medicor, Izola, Slovenia, EU. 4 complex Atrial Septal Defect closures. May 14, 2011 Page 63 of 65 Curriculum Vitae 4. Saibal Kar, M.D, FAHA, FACC, FSCAI Percutaneous Mitral Valve Repair (evalve Inc) Ziyad Hijazi, Sept 2, 2009. Dr Michael Mack, (one case)October 28, 2009, October 14, 2010. Dr Darren Walters (2 cases) Dr David Muller (1 case) Dr David Muller, (1 case), St Vincent Hospital, Sydney, Australia, August 13, 2012 Prof Teguh Santoso (4 cases). Medistra Hospital, Jakarta, Indonesia. February 23, 24, 2013 Dr Ravinay Bhindi and Dr Peter Jensen(3 cases), Northshore Private Hospital, Sydney, Australia, March 28,2013 Prof Teguh Santoso(2 cases), Medistra Hospital, Jakarta, Indonesia, April 21, 2013 Dr Ravinay Bhindi and Dr Peter Jensen(1case), Northshore Private Hospital, Sydney, Australia, October 17,2013 Dr Anthony Walton, Dr Stephen Duffy (2 cases), Alfred Hospital, Melbourne, Australia, October 18, 2013 Prof Teguh Santoso (3 cases). Medistra Hospital, Jakarta, Indonesia, November 16, 2013 5. Atrial appendage occlusion ( Watchman Device)) Prof Gerhard Schuller, ( 4 cases)Liepzig Heart Center, Liepzig, Germany, Aug 4, 2009 Dr Jeffrey Allison, (3 cases) Monash Medical Center, Melbourne, Australia, Nov 24, 2009 Dr Karen Phillips, (3 cases), Greenslopes Hospital, Brisbane, Australia, Nov 25, 2009. Dr Paul Sparks, (3 cases), Royal Melbourne Hospital, Melbourne, Australia, Nov 27, 2009. Dr Halkin Amir, Dr Raphael Rosso, Dr Itzhak Herz,(2 cases) Ichilov Medical Center, Tel-Aviv, Israel, May 30, 2010. Prof Michael Glikson, Dr Victor Guetta, Sheba Medical Center, Tel Hashomer, Israel. June 1, 2010 (3 cases) Dr Pak, Severence Hospital, Seoul, Korea( 2 cases) Dr Young-Keun On, Samsung Medical Center, Seoul, Korea (one case) . Dr Young Hoon Kim, Korea University Medical Center, Seoul, Korea (one case) Dr Matthew Price and Dr Gibson, Scripps Green Hospital, La Jolla, CA ( two cases), April 2011 Dr James Stewart, Mercy Hospital, Auckland, New Zealand (2 cases) Sept 7, 2011 Dr Teguh Santoso, Jakarta, Indonesia, (9 cases), January 14, 15th, 2012 Dr Alexander Black, Geelong Hospital (2 cases), Australia February 16, 2012 Dr Darren Walters, Prince Charles Hospital (3 cases), Brisbane, Australia, February 17, 2012 Prof Teguh Santoso, Medistra HospitalJakarta, Indonesia (5 cases), February 26, 2012 Dr. Gi-Byung Nam, Dr Won-Jang Kim (2 cases), ASAN Medical Center, Seoul, Korea, September 18, 2012 Dr Cheol-Woong Yu, Dr Rakyung Choy, Dr Sangwon Park, (2 cases), Sejong General Hospital, Seoul, Korea Dr Gabriel Yip, and Dr Yat Yin Lam. Grantham Hospital, Hongkong, (2 cases), October, 19, 2012 St Mary Hospital, Seoul, Korea, November 22, 2012 Dr Jason Chan, Dr Michael Lee Queen Elizabeth Hospital, Hongkong ( 2 cases). February 25, 2013 Dr Michael Neuyen, and Dr Andrew Liu, (3 cases), Fremantle Hospital, Western Australia, March 26, 2013 Dr Gregory Szto(2 cases). Peninsula Private Hospital, Frankston, Australia, March 27, 2013. Dr Rodney Teperman (2 cases), Peninsula Private Hospital, Frankston, Victoria, Australia. March 27, 2013 Dr ……………….. (2 cases), Hospital, Kuala Lumpur, Malaysia, November 12. 2013 Dr (2 cases), Hospital, Bangkok, Thailand, November 13, 2013. Dr (2 cases) Police Hospital, Bangkok, Thailand, November 13, 2013 Dr (1 case), Hospital, Bangkok, Thailand, November 15, 2013 6. Coherex PFO closure device Dr Marko Noc, Medicor, Izola, Slovenia.(4 cases) Dec 5, 6, 2009 and Sept 12, 2010 (5 cases) 7. Coherex WaveCrest Left Atrial Appendage Occluder Page 64 of 65 Curriculum Vitae Saibal Kar, M.D, FAHA, FACC, FSCAI Dr Karen Phillips, Dr Julie Humphries (2 cases), Greenslopes Hospital, Brisbance, Australia, Sept 26, 2011. Dr Ian Meredith, Dr Jeffrey Allison, Dr Richard Harper (2 cases), Monash Medical Center, Melbourne, Australia, Sept 28, 2011 Dr Marko Noc,(3 cases). Medicor, Izola, Slovenia Dr David Muller (1 case), St Vincent Hosptial, Sydney, Australia. August 14, 2012 Dr Marko Noc (2 cases), Medicor, Izola, Slovenia, September 30, 2012 L Dr Marko Noc (1 case), Medicor, Izola, Slovenia, December 15, 2012 8. Percutaneous Mitral Valvuloplasty Dr Hirsh Naik, West Valley Hospital, Phoenix, One case, January 6, 2012 Course Directors 1. 2. Atrial Septal Defect Closure Course, July 7-8, 2011, Cedars Sinai Medical Center, Los Angeles, CA. 1st International Symposium on Left Atrial Appendage. Kansas City. US., March 1-2, 2013 Page 65 of 65