INTERNATIONAL SCHOOL OF IMMUNOLOGY 2011 28 March – 1 April SOCIEDADE PORTUGUESA DE IMUNOLOGIA TAVIRA VILA GALÉ ALBACORA Programme in detail Sunday, 27th March 2011 20.30 WELCOME Margarida Correia-Neves Monday, 28th March 2011 9.00 – 13.00 MORNING SESSION - HEMATOPOIESIS Lecturer: Ana Cumano Host: Henrique Veiga-Fernandes Student Presentations P1. “Retinoic Acid in Enteric Lymphoid Organogenesis” Manuela Ferreira (Portugal) P2. “TLRs as new players in lymphocyte development” Alessandra Granato (France) P3. “Classifying the neonatal innate and adaptive immune functions in response to pathogens and microbial components can provide increased strategy for vaccine development” Brian Mozeleski (France) P4. “Thymic atrophy upon infection with a high virulent strain of Mycobacterium avium” Palmira Barreira-Silva (Portugal) Coffee break at 10.30-11.00h 13.00 14.30 – 18.30 LUNCH AFTERNOON SESSION - B CELL DIFFERENTIATION AND ACTIVATION Lecturer: Paulo Vieira Host: Vasco M. Barreto Student Presentations P5. “B1 cells of the NOD mouse display abnormal immunophenotypes: possible role on type 1 diabetes early steps” Joana Côrte-Real (Portugal) P6. “Antibodies against sand fly saliva: a suitable tool for epidemiological studies” Iva Rohousova (Czech Republic) 9 INTERNATIONAL SCHOOL OF IMMUNOLOGY 2011 28 March – 1 April SOCIEDADE PORTUGUESA DE IMUNOLOGIA TAVIRA VILA GALÉ ALBACORA P7. “Are early immune responses in Plasmodium falciparum infected individuals in ethnic groups with different susceptibility to malaria subject to epigenetic regulation?” Pablo Giusti (Sweden) P8. “Ablation of IL-10 signaling through TLR2 led to enhanced Group B Streptococcus control” Elva B. Andrade (Portugal) Coffee break at 16.00-16.30h 18.30 – 20.30 INTERACTION BETWEEN LECTURERS, HOSTS AND STUDENTS 20.30 DINNER Tuesday, 29th March 2011 9.00 – 13.00 MORNING SESSION – DENDRITIC CELLS Lecturer: Caetano Reis e Sousa Host: Margarida Saraiva Student Presentations P9. “A role for Heme oxygenase-1 in dendritic cell biology” Ivo Marguti (Portugal) P10. “The role of Heme oxygenase‐1 in dendritic cells and T cells modulation during the ischemia and reperfusion injury development” Marianne T. Amano (Brazil) P11. “Role of TLR2, TLR4 and MyD88 in an experimental model of tubulointerstitial nephritis” Matheus Correa-Costa (Brazil) P12. “TLR2, TLR4 and MyD88 and Th1/Th2 balance and in the development of renal fibrosis” Tárcio T. Braga (Brazil) P13. “Interaction of antithymocyte globulins with dendritic cell antigens” Judith Leitner (Austria) Coffee break at 10.30-11.00h 13.00 14.30 – 18.30 LUNCH AFTERNOON SESSION - T CELL DIFFERENTIATION AND TOLERANCE Lecturer: Christophe Benoist Host: Nuno L. Alves Student Presentations 9 INTERNATIONAL SCHOOL OF IMMUNOLOGY 2011 28 March – 1 April SOCIEDADE PORTUGUESA DE IMUNOLOGIA TAVIRA VILA GALÉ ALBACORA P14. “Role of diacylglycerol in the control of T cell development and homeostasis” María Almena (Spain) P15. “Aire-regulated gene expression mainly occurs on transcriptional level and is promoter-independent” Julia Maslovskaja (Estonia) P16. “Antigen-specific T cell responses in a humanized mouse model that is tolerant to coagulation factor VIIa” Christine Lenk (Austria) P17. “Is T cell recirculation back to the thymus essential to mount an immune response to infection in this organ?” Cláudia Nóbrega (Portugal) P18. “Intrathymic transplantation of bone marrow derived progenitors provides long-term thymopoiesis” Rita Vicente (France) Coffee break at 16.00-16.30h 18.30 – 20.30 INTERACTION BETWEEN LECTURERS, HOSTS AND STUDENTS 20.30 DINNER Wednesday, 30th March 2011 9.00 – 13.00 MORNING SESSION – γδ T CELL DIFFERENTIATION AND ACTIVATION Lecturer: Adrian C. Hayday Host: Bruno Silva-Santos Student Presentations P19. “Pre- and post-transcriptional mechanisms of functional differentiation of γδ T cells in vivo” Nina Schmolka (Portugal) P20. “Understanding the dual role of murine γδ T cells in tumour surveillance and tumour progression” Margarida Rei (UK) P21. “CCL25 induces the migration of α4β7+ γδ T lymphocytes during allergic reaction and modulates IL-17 production” Maria F. S. Costa (Brazil) P22. “Investigation of PI3Kδ and PI3Kγ function in IL-17A production in the context of psoriasis” Anne Roller (Switzerland) Coffee break at 10.30-11.00h 13.00 LUNCH 9 INTERNATIONAL SCHOOL OF IMMUNOLOGY 2011 28 March – 1 April SOCIEDADE PORTUGUESA DE IMUNOLOGIA TAVIRA VILA GALÉ ALBACORA 14.30 – 18.30 AFTERNOON SESSION – NATURAL KILLER CELLS Lecturer: Lewis L. Lanier Host: Paulo Rodrigues-Santos Student Presentations P23. “Microbial ligands and cellular receptors involved in direct recognition of M. bovis, bacillus of Calmette and Guérin by human NK cells” Anna Aulicino (Italy) P24. “Ral GTPases in cell-mediated cytotoxicity” Jesús Sánchez-Ruiz (Spain) P25. “Class I antigen presentation in sea bass (Dicentrarchus labrax, L): identification of key antigen processing and presentation genes” Rute D. Pinto (Portugal) P26. “Helicobacter pylori HP986 acts via TNFR1 to induce simultaneously proinflammatory and proapoptotic responses” Suhail A. Ansari (India) P27. “Pregnancy-associated Malaria Phenotype induced by Plasmodium berghei mutants” Lurdes Rodrigues-Duarte (Portugal) Coffee break at 16.00-16.30h 18.30 – 20.30 INTERACTION BETWEEN LECTURERS, HOSTS AND STUDENTS 20.30 DINNER Thursday, 31th March 2011 9.00 – 13.00 MORNING SESSION – T CELL ACTIVATION AND IMMUNE RESPONSE TO INFECTION Lecturer: Anne O’Garra Host: Michael Parkhouse Student Presentations P28. “Biomarkers of protection in the host response to BCG‐vaccination and Mycobacterium tuberculosis” Ruth E. Thom (UK) P29. “Interleukin 12 is expressed differently after infection with Mycobacterium tuberculosis or M. bovis BCG” Maria Teixeira-Coelho (Portugal) P30. “The role of adaptive immunity in Mycobacterium ulcerans infection” Alexandra G. Fraga (Portugal) 9 INTERNATIONAL SCHOOL OF IMMUNOLOGY 2011 28 March – 1 April SOCIEDADE PORTUGUESA DE IMUNOLOGIA TAVIRA VILA GALÉ ALBACORA P31. “Polarized endosomal tubulation in human dendritic cells upon cognate interaction with CD8+ T-cells” Ewaldus B. Compeer (The Netherlands) Coffee break at 10.30-11.00h 13.00 14.30 – 18.30 LUNCH AFTERNOON SESSION – ALLERGY Lecturer: Catherine M. Hawrylowicz Host: M. Francisca Moraes-Fontes Student Presentations P32. “STUB1 is a negative regulator of FOXP3 by ubiquitination mediated degradation” Zuojia Chen (China) P33. “The effect of ionizing radiation on the quantitative and functional parameters of regulatory T Cells in mice” Andrea Balogh (Hungary) P34. “Induction and expansion of regulatory T cells during pregnancy” Ana Teles (Germany) P35. “Toll‐Like Receptors 2, 4, 9 and Myd88 expression correlates with disease activity in experimental autoimmune encephalomyelitis” Emina Savic (Serbia) Coffee break at 16.00-16.30h 18.30 – 20.30 INTERACTION BETWEEN LECTURERS, HOSTS AND STUDENTS 20.30 DINNER Friday, 1st April 2011 9.00 – 13.00 MORNING SESSION – TRANSPLANTATION Lecturer: Herman Waldmann Host: Luís Graça Student Presentations P36. “Towards the generation of human TFPI transgenic pigs with improved features for xenotransplantation” Ana C. Cunha (Portugal) P37. “Identifying the role of CD4+ T cells in the development of inhibitory antibodies against coagulation factor VIII in Hemophilia A: How translational research is applied to advance future patient care” 9 INTERNATIONAL SCHOOL OF IMMUNOLOGY 2011 28 March – 1 April SOCIEDADE PORTUGUESA DE IMUNOLOGIA TAVIRA VILA GALÉ ALBACORA Christoph Hofbauer (Austria) P38. “Establishing a mouse model reporter for aryl hydrocarbon receptor in the immune system” Ella Rosenzweig (UK) P39. “Role of the Fms-Like tyrosine kinase 3 ligand induced dendritic cells for development of antigen induced arthritis” Mattias Svensson (Sweden) Coffee break at 10.30-11.00h 13.00 14.30 – 18.30 LUNCH AFTERNOON SESSION – PRIMARY IMMUNODEFICIENCIES Lecturer: Steven Holland Host: Laura Marques Student Presentations P40. “Long‐term impact of thymectomy performed in early infancy” Susana Lopes-Silva (Portugal) P41. “Naïve CD4+ T-cell disturbances and HIV/AIDS” Rita Tendeiro (Portugal) P42. “HIV 2 impact on lymphoid tissues” Susana M. Fernandes (Portugal) P43. “Regulation of IL-1β release by human neutrophils” María L. Gabelloni (Argentina) Coffee break at 16.00-16.30h 18.30 FINAL KEYNOTE António Coutinho CLOSING REMARKS Ana E. Sousa 20.30 FAREWELL DINNER 9